Department of Health and Human Services August 2011 – Federal Register Recent Federal Regulation Documents

National Center for Research Resources; Notice of Closed Meetings
Document Number: 2011-22301
Type: Notice
Date: 2011-08-31
Agency: Department of Health and Human Services, National Institutes of Health
National Center for Research Resources; Amended Notice of Meeting
Document Number: 2011-22300
Type: Notice
Date: 2011-08-31
Agency: Department of Health and Human Services, National Institutes of Health
National Institute on Aging; Notice of Closed Meetings
Document Number: 2011-22299
Type: Notice
Date: 2011-08-31
Agency: Department of Health and Human Services, National Institutes of Health
Center for Scientific Review; Notice of Closed Meeting
Document Number: 2011-22298
Type: Notice
Date: 2011-08-31
Agency: Department of Health and Human Services, National Institutes of Health
Center for Scientific Review; Notice of Closed Meetings
Document Number: 2011-22297
Type: Notice
Date: 2011-08-31
Agency: Department of Health and Human Services, National Institutes of Health
Statement of Organization, Functions and Delegations of Authority
Document Number: 2011-22261
Type: Notice
Date: 2011-08-31
Agency: Department of Health and Human Services, Health Resources and Services Administration
Supplement to the FY2010 Single-Source Cooperative Agreement With the World Health Organization (WHO)
Document Number: 2011-22214
Type: Notice
Date: 2011-08-31
Agency: Department of Health and Human Services
In FY 2011, HHS/ASPR/BARDA plans to supplement the FY2010 ``Single-Source Cooperative Agreement with the World Health Organization (WHO) to Continue Development of Sustainable Influenza Vaccine Production Capacity in Under Resourced Nations''. BARDA currently funds the development of vaccine manufacturing capacity in ten developing and emerging-economy countries worldwide via a cooperative agreement with the World Health Organization (WHO). The amount of Single Source Award is $6,021,535. The project period is September 1, 2011, through August 31, 2012.
National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meeting
Document Number: 2011-22213
Type: Notice
Date: 2011-08-31
Agency: Department of Health and Human Services, National Institutes of Health
National Center for Research Resources Notice of Closed Meeting
Document Number: 2011-22211
Type: Notice
Date: 2011-08-31
Agency: Department of Health and Human Services, National Institutes of Health
National Institute of Allergy and Infectious Diseases; Notice of Closed Meetings
Document Number: 2011-22210
Type: Notice
Date: 2011-08-31
Agency: Department of Health and Human Services, National Institutes of Health
Center for Scientific Review; Notice of Closed Meetings
Document Number: 2011-22209
Type: Notice
Date: 2011-08-31
Agency: Department of Health and Human Services, National Institutes of Health
National Institute on Aging; Notice of Closed Meetings
Document Number: 2011-22208
Type: Notice
Date: 2011-08-31
Agency: Department of Health and Human Services, National Institutes of Health
Office of the Director, National Institutes of Health; Notice of Meeting
Document Number: 2011-22207
Type: Notice
Date: 2011-08-31
Agency: Department of Health and Human Services, National Institutes of Health
Center for Scientific Review; Amended Notice of Meeting
Document Number: 2011-22204
Type: Notice
Date: 2011-08-31
Agency: Department of Health and Human Services, National Institutes of Health
Award of an Urgent Single-Source Grant to Survivors of Torture International (SOTI) in San Diego, CA; Correction
Document Number: 2011-22196
Type: Notice
Date: 2011-08-30
Agency: Department of Health and Human Services, Office of Refugee Resettlement, Refugee Resettlement Office, Children and Families Administration
The Office of Refugee Resettlement, ACF, HHS published a document in the Federal Register of August 16, 2011 (76 FR 50744), concerning the issuance of an urgent single-source grant to Survivors of Torture, International (SOTI), San Diego, CA. The document contained incorrect information in citing the statutory authority for making this award. Correction: In the Federal Register of August 16, 2011 (76 FR 50744), ORR omitted the primary authority for issuing this award. The notice should have included the following: Awards announced in this notice are authorized by the Torture Victims Relief Act (TVRA) of 1998,'' Public Law 105-320 (22 U.S.C. 2152 note), reauthorized by Public Law 109-165 in January 2006. Section 5 (a) of the TVRA of 1998 provides for ``Assistance for Treatment of Torture Victims. The Secretary of Health and Human Services may provide grants to programs in the United States to cover the cost of the following services: (1) Services for the rehabilitation of victims of torture, including treatment of the physical and psychological effects of torture. (2) Social and legal services for victims of torture. (3) Research and training for health care providers outside of treatment centers, or programs for the purpose of enabling such providers to provide the services described in paragraph (1).'' And by Section 412 (c)(1)(A) of the Immigration and Nationality Act (INA) (8 U.S.C. 1522(c)(1)(A), as amended, and the Refugee Assistance Extension Act of 1986, Public Law 99-605, Nov 6, 1986, 100 Stat. 3449.
Agency Information Collection Request; 30-Day Public Comment Request
Document Number: 2011-22168
Type: Notice
Date: 2011-08-30
Agency: Department of Health and Human Services
Agency Information Collection Request. 30-Day Public Comment Request
Document Number: 2011-22166
Type: Notice
Date: 2011-08-30
Agency: Department of Health and Human Services
Draft Guidance for Industry on Tablet Scoring: Nomenclature, Labeling, and Data for Evaluation; Availability
Document Number: 2011-22146
Type: Notice
Date: 2011-08-30
Agency: Food and Drug Administration, Department of Health and Human Services
The Food and Drug Administration (FDA) is announcing the availability of a draft guidance for industry entitled ``Tablet Scoring: Nomenclature, Labeling, and Data for Evaluation.'' This draft guidance provides recommendations to sponsors of new drug applications (NDAs) and abbreviated new drug applications (ANDAs) regarding what criteria should be met to facilitate the evaluation and labeling of tablets that have been scored. (A scoring feature facilitates tablet splitting, which is the practice of breaking or cutting a higher- strength tablet into smaller portions.) Specifically, this draft guidance recommends guidelines to follow, data to provide, and criteria to meet and detail in an application to approve a scored tablet; and nomenclature and labeling for approved scored tablets. This guidance does not address specific finished-product release testing, where additional requirements may be appropriate for scored tablets.
Determination That TALWIN COMPOUND (Aspirin; Pentazocine Hydrochloride) Tablets, 325 Milligrams; Equivalent to 12.5 Milligram Base, Were Not Withdrawn From Sale for Reasons of Safety or Effectiveness
Document Number: 2011-22145
Type: Notice
Date: 2011-08-30
Agency: Food and Drug Administration, Department of Health and Human Services
The Food and Drug Administration (FDA) has determined that TALWIN COMPOUND (aspirin; pentazocine hydrochloride (HCl)) tablets, 325 milligrams (mg); equivalent to (EQ) 12.5 mg base, were not withdrawn from sale for reasons of safety or effectiveness. This determination will allow FDA to approve abbreviated new drug applications (ANDAs) for aspirin; pentazocine HCl tablets, 325 mg; EQ 12.5 mg base, if all other legal and regulatory requirements are met.
FDA's Public Database of Products With Orphan-Drug Designation: Replacing Non-Informative Code Names With Descriptive Identifiers
Document Number: 2011-22144
Type: Notice
Date: 2011-08-30
Agency: Food and Drug Administration, Department of Health and Human Services
The Food and Drug Administration (FDA), Office of Orphan Products Development, is announcing that it has replaced non- informative code names with descriptive identifiers on its public database of products that have received orphan-drug designation. The Orphan Drug Act mandates that FDA provide notice to the public respecting the designation of a drug as an orphan-drug. FDA typically provides public notice by publishing a drug's generic or trade name upon orphan designation. Where a designated drug does not have a generic or trade name, publishing a non-informative code name does not meet the statutory disclosure requirement because the public would not be able to identify the drug that has received orphan designation.
Determination That OPANA ER (Oxymorphone Hydrochloride) Extended-Release Tablets, 7.5 Milligrams and 15 Milligrams, Were Not Withdrawn From Sale for Reasons of Safety or Effectiveness
Document Number: 2011-22143
Type: Notice
Date: 2011-08-30
Agency: Food and Drug Administration, Department of Health and Human Services
The Food and Drug Administration (FDA) has determined that OPANA ER (oxymorphone hydrochloride (HCl)) extended-release tablets, 7.5 milligrams (mg) and 15 mg, were not withdrawn from sale for reasons of safety or effectiveness. This determination means that FDA will not begin procedures to withdraw approval of abbreviated new drug applications (ANDAs) that refer to these drug products, and it will allow FDA to continue to approve ANDAs for oxymorphone HCl extended- release tablets, 7.5 mg and 15 mg, if all other legal and regulatory requirements are met.
Effective Date of Requirement for Premarket Approval for Cardiovascular Permanent Pacemaker Electrode; Correction
Document Number: 2011-22107
Type: Proposed Rule
Date: 2011-08-30
Agency: Food and Drug Administration, Department of Health and Human Services
The Food and Drug Administration (FDA) is correcting a proposed rule that appeared in the Federal Register of August 8, 2011 (76 FR 48058). The document proposed to require the filing of a premarket approval application or a notice of completion of a product development protocol for the class III preamendments device: Cardiovascular permanent pacemaker electrode. The document was published with an incorrect Internet address for the first reference in the References section. This document corrects that error.
Advisory Committee; Change of Name and Function; Technical Amendment
Document Number: 2011-22105
Type: Rule
Date: 2011-08-30
Agency: Food and Drug Administration, Department of Health and Human Services
The Food and Drug Administration (FDA) is amending the standing advisory committees' regulations to change the name and function of the Anesthetic and Life Support Drugs Advisory Committee. This action is being taken to reflect changes made to the charter for this advisory committee.
Agency Information Collection Activities: Submission for OMB Review; Comment Request
Document Number: 2011-22097
Type: Notice
Date: 2011-08-30
Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Administration
Agency Information Collection Activities: Submission for OMB Review; Comment Request
Document Number: 2011-22096
Type: Notice
Date: 2011-08-30
Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Administration
Agency Information Collection Activities: Submission for OMB Review; Comment Request
Document Number: 2011-22095
Type: Notice
Date: 2011-08-30
Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Administration
Availability of Final Toxicological Profile for RDX
Document Number: 2011-22080
Type: Notice
Date: 2011-08-30
Agency: Agency for Toxic Substances and Disease Registry, Department of Health and Human Services
This notice announces the availability of one toxicological profile, prepared by ATSDR for the Department of Defense, on Royal Demolition eXplosive (RDX), chemical name hexahydro-1,3,5-trinitro- 1,3,5-triazine, also known as cyclonite.
Proposed Information Collection Activity; Comment Request
Document Number: 2011-22078
Type: Notice
Date: 2011-08-30
Agency: Department of Health and Human Services, Children and Families Administration
Fee for Using a Priority Review Voucher in Fiscal Year 2012
Document Number: 2011-22062
Type: Notice
Date: 2011-08-30
Agency: Food and Drug Administration, Department of Health and Human Services
The Food and Drug Administration (FDA) is announcing the fee rates for using a tropical disease priority review voucher for fiscal year (FY) 2012. The Federal Food, Drug, and Cosmetic Act (the FD&C Act), as amended by the Food and Drug Administration Amendments Act of 2007 (FDAAA), authorizes FDA to determine and collect priority review user fees for certain applications for approval of drug or biological products when those applications use a priority review voucher awarded by the Secretary of Health and Human Services. These vouchers are awarded to the sponsors of certain tropical disease product applications, submitted after September 27, 2007, upon FDA approval of such applications. The amount of the fee to be submitted to FDA with applications using a priority review voucher is determined each FY based on the average cost incurred by FDA in the review of a human drug application subject to priority review in the previous FY. This notice establishes the priority review fee rate for FY 2012.
Delegation of Authorities
Document Number: 2011-22042
Type: Notice
Date: 2011-08-30
Agency: Department of Health and Human Services
National Institutes of Health
Document Number: 2011-21980
Type: Notice
Date: 2011-08-29
Agency: Department of Health and Human Services, National Institutes of Health
Under the provisions of Section 3507(a)(l)(D) of the Paperwork Reduction Act of 1995 for the opportunity for public comment on the proposed data collection projects, the Center for Scientific Review (CSR), National Institutes of Health (NIH), has submitted to the Office of Management and Budget (OMB) a request to review and approve the information collection listed below. This proposed information collection was previously published in the Federal Register on July 22, 2011 (Vol. 76, No. 141, p. 44020) and allowed 60-days for public comment. There was one public comment received during this time. The purpose of this notice is to allow 30 days for public comment. The National Institutes of Health may not conduct or sponsor and the respondent is not required to respond to, an information collection that has been extended, revised, or implemented on or after October 1, 1995, unless it displays a currently valid OMB control number. Proposed Collection: Title: Extension of Generic Clearance for Voluntary Partner and Customer Satisfaction Surveys. Type of Information Collection Request: Extension. Need and Use of Information Collection: The information collected in these surveys will be used by the Center for Scientific Review management and personnel: (1) To assess the quality of the modified operations and processes now used by CSR to review grant applications; (2) To assess the quality of service provided by CSR to our customers; (3) To enable identification of the most promising biomedical research that will have the greatest impact on improving public health by using a peer review process that is fair unbiased from outside influence, timely, and (4) To develop new modes of operation based on customer need and customer feedback about the efficacy of implemented modifications. These surveys will almost certainly lead to quality improvement activities to enhance and/or streamline CSR's operations. The major mechanism by which CSR will request input is through surveys. The major initiatives ongoing at the present time include: Shortening the review and application process, shortening the grant application, recruiting the best reviewers by developing additional review modes, improving study section alignment to ensure the best reviews, and others. Surveys will be collected via Internet. Information gathered from these surveys will be presented to, and used directly by, CSR management to enhance the operations, processes, organization of, and services provided by the Center. Frequency of Response: The participants will respond once, unless there is a compelling reason for a subsequent survey. Affected public: Universities, not-forprofit institutions, business or other forprofit, small businesses and organizations, and individuals. Type of Respondents: Adult scientific professionals.
National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings
Document Number: 2011-21979
Type: Notice
Date: 2011-08-29
Agency: Department of Health and Human Services, National Institutes of Health
National Institute of Biomedical Imaging and Bioengineering; Notice of Closed Meeting
Document Number: 2011-21978
Type: Notice
Date: 2011-08-29
Agency: Department of Health and Human Services, National Institutes of Health
National Institute of Allergy and Infectious Diseases; Notice of Closed Meetings
Document Number: 2011-21976
Type: Notice
Date: 2011-08-29
Agency: Department of Health and Human Services, National Institutes of Health
National Institute of Allergy and Infectious Diseases Notice of Closed Meetings
Document Number: 2011-21975
Type: Notice
Date: 2011-08-29
Agency: Department of Health and Human Services, National Institutes of Health
National Eye Institute Notice of Closed Meeting
Document Number: 2011-21974
Type: Notice
Date: 2011-08-29
Agency: Department of Health and Human Services, National Institutes of Health
National Cancer Institute Notice of Meeting
Document Number: 2011-21973
Type: Notice
Date: 2011-08-29
Agency: Department of Health and Human Services, National Institutes of Health
Draft Guidance for Industry on Oversight of Clinical Investigations: A Risk-Based Approach to Monitoring; Availability
Document Number: 2011-21972
Type: Notice
Date: 2011-08-29
Agency: Food and Drug Administration, Department of Health and Human Services
The Food and Drug Administration (FDA) is announcing the availability of a draft guidance for industry entitled ``Oversight of Clinical Investigations: A Risk-Based Approach to Monitoring.'' This guidance is intended to assist sponsors in developing risk-based monitoring strategies and plans for clinical investigations of human drugs, biologics, medical devices, and combinations thereof. The overarching goal of this guidance is to enhance human subject protection and the quality of clinical trial data. The guidance is intended to make clear that sponsors can use a variety of approaches to meet their monitoring responsibilities when conducting investigational new drug (IND) or investigational device exemption (IDE) studies.
Center For Scientific Review; Notice of Closed Meetings
Document Number: 2011-21970
Type: Notice
Date: 2011-08-29
Agency: Department of Health and Human Services, National Institutes of Health
Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Meeting
Document Number: 2011-21967
Type: Notice
Date: 2011-08-29
Agency: Department of Health and Human Services, National Institutes of Health
Center for Scientific Review; Notice of Closed Meetings
Document Number: 2011-21963
Type: Notice
Date: 2011-08-29
Agency: Department of Health and Human Services, National Institutes of Health
National Institute of Mental Health; Notice of Workshop
Document Number: 2011-21961
Type: Notice
Date: 2011-08-29
Agency: Department of Health and Human Services, National Institutes of Health
Submission for OMB Review; Comment Request
Document Number: 2011-21868
Type: Notice
Date: 2011-08-29
Agency: Department of Health and Human Services, Administration for Children and Families, Children and Families Administration
Submission for OMB Review; Comment Request
Document Number: 2011-21863
Type: Notice
Date: 2011-08-29
Agency: Department of Health and Human Services, Administration for Children and Families, Children and Families Administration
Agency Information Collection Activities: Proposed Collection: Comment Request
Document Number: 2011-21942
Type: Notice
Date: 2011-08-26
Agency: Department of Health and Human Services, Health Resources and Services Administration
Agency Information Collection Activities: Submission for OMB Review; Comment Request
Document Number: 2011-21932
Type: Notice
Date: 2011-08-26
Agency: Centers for Medicare & Medicaid Services, Department of Health and Human Services
Agency Information Collection Activities: Proposed Collection; Comment Request
Document Number: 2011-21903
Type: Notice
Date: 2011-08-26
Agency: Centers for Medicare & Medicaid Services, Department of Health and Human Services
Food Safety Modernization Act Domestic and Foreign Facility Reinspections, Recall, and Importer Reinspection User Fee Rates for Fiscal Year 2012; Correction
Document Number: 2011-21895
Type: Notice
Date: 2011-08-26
Agency: Food and Drug Administration, Department of Health and Human Services
The Food and Drug Administration (FDA) is correcting a notice that appeared in the Federal Register of August 1, 2011 (76 FR 45820). The document announced the fiscal year 2012 fee rates for certain domestic and foreign facility reinspections, failure to comply with a recall order, and importer reinspections that are mandated in the FDA Food Safety Modernization Act (FSMA). The document was published with two typographical errors. This document corrects those errors.
Board of Scientific Counselors, Office of Public Health Preparedness and Response (BSC, OPHPR)
Document Number: 2011-21887
Type: Notice
Date: 2011-08-26
Agency: Centers for Disease Control and Prevention, Department of Health and Human Services
Negotiated Rulemaking Committee on Designation of Medically Underserved Populations and Health Professional Shortage Areas; Notice of Meeting
Document Number: 2011-21883
Type: Proposed Rule
Date: 2011-08-26
Agency: Department of Health and Human Services
In accordance with section 10(a)(2) of the Federal Advisory Committee Act (Pub. L. 92-463), notice is hereby given of the following meeting of the Negotiated Rulemaking Committee on Designation of Medically Underserved Populations and Health Professional Shortage Areas.