Sunshine Act Meeting, 31784 [2017-14450]
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31784
Federal Register / Vol. 82, No. 130 / Monday, July 10, 2017 / Notices
inhibitory nucleic acids to cells in a
targeted and efficient manner are
disclosed in this invention. The
complexes and methods are based on
utilizing a cell surface receptor targeting
ligand and a nucleic acid binding
domain that binds an inhibitory nucleic
acid, to efficiently deliver the inhibitory
oligonucleotide to the cell that
expresses the cell surface receptor
targeting ligand. The compositions can
be used to silence gene expression in a
cell or to deliver agents to a target cell,
thereby treating or preventing a disease
or disorder.
The invention has broad utility as the
cell surface receptor targeting ligand
could be any molecule such as,
cytokines, chemokines, antibodies or
growth factors, that binds to a unique
cellular receptor or cell surface antigen.
Cytokines are small secreted proteins
which mediate and regulate immunity,
inflammation, and hematopoiesis.
Chemokines are a family of small
cytokines that are secreted by cells.
They act on their target cells by binding
specific membrane receptors. TARC/
CCL17 and RANTES/CCL5 are examples
of chemokines whose receptors are
CCR4 and CCR5, respectively.
The complexes of this invention
could inactivate immune cells by
delivering oligonucleotides. For
example, the TARC-nucleic acid
binding domain complex referred to as
TARC-arp, has been shown to deliver siFoxP3 oligonucleotide into CCR4expressing cancer cells that will
specifically only inactivate FoxP3
expression. Chemokine-based gene
silencing can be therapeutically used to
modulate immune cells and improve
outcome of diseases, such as by
inactivating Tregs to block cancer
escape and metastasis.
This notice is made in accordance
with 35 U.S.C. 209 and 37 CFR part 404.
The prospective Exclusive Patent
License will be royalty bearing and may
be granted unless within fifteen (15)
days from the date of this published
notice, the National Cancer Institute
receives written evidence and argument
that establishes that the grant of the
license would not be consistent with the
requirements of 35 U.S.C. 209 and 37
CFR part 404.
Complete applications for a license in
the prospective field of use that are filed
in response to this notice will be treated
as objections to the grant of the
contemplated Exclusive Patent License
Agreement. Comments and objections
submitted to this notice will not be
made available for public inspection
and, to the extent permitted by law, will
not be released under the Freedom of
Information Act, 5 U.S.C. 552.
VerDate Sep<11>2014
16:08 Jul 07, 2017
Jkt 241001
Dated: June 27, 2017.
Richard U. Rodriguez,
Associate Director, Technology Transfer
Center, National Cancer Institute.
[FR Doc. 2017–14370 Filed 7–7–17; 8:45 am]
BILLING CODE 4140–01–P
INTERNATIONAL TRADE
COMMISSION
[USITC SE–17–027]
Sunshine Act Meeting
United
States International Trade Commission.
TIME AND DATE: July 12, 2017 at 11:00
a.m.
PLACE: Room 101, 500 E Street SW.,
Washington, DC 20436, Telephone:
(202) 205–2000.
STATUS: Open to the public.
MATTERS TO BE CONSIDERED:
1. Agendas for future meetings: None.
2. Minutes.
3. Ratification List.
4. Vote in Inv. No. 731–TA–410
(Fourth Review) (Light-Walled
Rectangular Pipe from Taiwan). The
Commission is currently scheduled to
complete and file its determination and
views of the Commission by July 25,
2017.
5. Vote in Inv. No. 731–TA–703
(Fourth Review) (Furfuryl Alcohol from
China). The Commission is currently
scheduled to complete and file its
determination and views of the
Commission by July 28, 2017.
6. Outstanding action jackets: None.
In accordance with Commission
policy, subject matter listed above, not
disposed of at the scheduled meeting,
may be carried over to the agenda of the
following meeting.
AGENCY HOLDING THE MEETING:
By order of the Commission.
Issued: July 5, 2017.
William R. Bishop,
Supervisory Hearings and Information
Officer.
[FR Doc. 2017–14450 Filed 7–6–17; 11:15 am]
BILLING CODE 7020–02–P
UNITED STATES INTERNATIONAL
TRADE COMMISSION
[USITC SE–17–028]
Sunshine Act Meeting
United
States International Trade Commission.
TIME AND DATE: July 14, 2017 at 11:00
a.m.
PLACE: Room 101, 500 E Street SW.,
Washington, DC 20436, Telephone:
(202) 205–2000.
AGENCY HOLDING THE MEETING:
PO 00000
Frm 00035
Fmt 4703
Sfmt 4703
STATUS:
Open to the public.
MATTERS TO BE CONSIDERED:
1. Agendas for future meetings: none.
2. Minutes.
3. Ratification List.
4. Vote in Inv. Nos. 701–TA–579–580
and 731–TA–1369–1373
(Preliminary)(Fine Denier Polyester
Staple Fiber from China, India, Korea,
Taiwan, and Vietnam). The Commission
is currently scheduled to complete and
file its determinations on July 17, 2017;
views of the Commission are currently
scheduled to be completed and filed on
July 24, 2017.
5. Vote in Inv. Nos. 701–TA–581 and
731–TA–1374–1376 (Preliminary)
(Citric Acid and Certain Citrate Salts
from Belgium, Colombia, and Thailand).
The Commission is currently scheduled
to complete and file its determinations
on July 17, 2017; views of the
Commission are currently scheduled to
be completed and filed on July 24, 2017.
6. Outstanding action jackets: None.
In accordance with Commission
policy, subject matter listed above, not
disposed of at the scheduled meeting,
may be carried over to the agenda of the
following meeting.
By order of the Commission.
Issued: July 5, 2017.
William R. Bishop,
Supervisory Hearings and Information
Officer.
[FR Doc. 2017–14449 Filed 7–6–17; 11:15 am]
BILLING CODE 7020–02–P
DEPARTMENT OF JUSTICE
[OMB Number 1122–0029]
Agency Information Collection
Activities; Proposed eCollection
eComments Requested; Extension of a
Currently Approved Collection
Office on Violence Against
Women, Department of Justice.
ACTION: 30-day notice.
AGENCY:
The Department of Justice,
Office on Violence Against Women
(OVW) will be submitting the following
information collection request to the
Office of Management and Budget
(OMB) for review and approval in
accordance with the Paperwork
Reduction Act of 1995. The proposed
information collection was previously
published on May 18, 2017, allowing for
a 60 day comment period.
DATES: Comments are encouraged and
will be accepted for 30 days until
August 9, 2017.
FOR FURTHER INFORMATION CONTACT:
Written comments and/or suggestion
SUMMARY:
E:\FR\FM\10JYN1.SGM
10JYN1
Agencies
[Federal Register Volume 82, Number 130 (Monday, July 10, 2017)]
[Notices]
[Page 31784]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2017-14450]
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INTERNATIONAL TRADE COMMISSION
[USITC SE-17-027]
Sunshine Act Meeting
AGENCY HOLDING THE MEETING: United States International Trade
Commission.
TIME AND DATE: July 12, 2017 at 11:00 a.m.
PLACE: Room 101, 500 E Street SW., Washington, DC 20436, Telephone:
(202) 205-2000.
STATUS: Open to the public.
MATTERS TO BE CONSIDERED:
1. Agendas for future meetings: None.
2. Minutes.
3. Ratification List.
4. Vote in Inv. No. 731-TA-410 (Fourth Review) (Light-Walled
Rectangular Pipe from Taiwan). The Commission is currently scheduled to
complete and file its determination and views of the Commission by July
25, 2017.
5. Vote in Inv. No. 731-TA-703 (Fourth Review) (Furfuryl Alcohol
from China). The Commission is currently scheduled to complete and file
its determination and views of the Commission by July 28, 2017.
6. Outstanding action jackets: None.
In accordance with Commission policy, subject matter listed above,
not disposed of at the scheduled meeting, may be carried over to the
agenda of the following meeting.
By order of the Commission.
Issued: July 5, 2017.
William R. Bishop,
Supervisory Hearings and Information Officer.
[FR Doc. 2017-14450 Filed 7-6-17; 11:15 am]
BILLING CODE 7020-02-P