Advisory Committee for Women's Services; Notice of Meeting, 54583-54584 [2016-19422]
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Federal Register / Vol. 81, No. 158 / Tuesday, August 16, 2016 / Notices
Agenda: To review and evaluate grant
applications.
Place: National Cancer Institute Shady
Grove, 9609 Medical Center Drive, Room
7W030, Rockville, MD 20850, (Telephone
Conference Call).
Contact Person: Nadeem Khan, Ph.D.,
Scientific Review Officer, Research
Technology and Contract Review Branch,
Division of Extramural Activities, National
Cancer Institute, 9609 Medical Center Drive,
Room 7W260, Rockville, MD 20892–9750,
240–276–5856, nadeem.khan@nih.gov.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.392, Cancer Construction;
93.393, Cancer Cause and Prevention
Research; 93.394, Cancer Detection and
Diagnosis Research; 93.395, Cancer
Treatment Research; 93.396, Cancer Biology
Research; 93.397, Cancer Centers Support;
93.398, Cancer Research Manpower; 93.399,
Cancer Control, National Institutes of Health,
HHS)
Dated: August 10, 2016.
Melanie J. Gray,
Program Analyst, Office of Federal Advisory
Committee Policy.
[FR Doc. 2016–19416 Filed 8–15–16; 8:45 am]
BILLING CODE 4140–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
Government-Owned Inventions;
Availability for Licensing
National Institutes of Health.
ACTION: Notice.
AGENCY:
The invention listed below is
owned by an agency of the U.S.
Government and is available for
licensing and/or co-development in the
U.S. in accordance with 35 U.S.C. 209
and 37 CFR part 404 to achieve
expeditious commercialization of
results of federally-funded research and
development. Foreign patent
applications are filed on selected
inventions to extend market coverage
for companies and may also be available
for licensing and/or co-development.
ADDRESSES: Invention Development and
Marketing Unit, Technology Transfer
Center, National Cancer Institute, 9609
Medical Center Drive, Mail Stop 9702,
Rockville, MD 20850–9702.
FOR FURTHER INFORMATION CONTACT:
Information on licensing and codevelopment research collaborations,
and copies of the U.S. patent
applications listed below may be
obtained by contacting: Attn. Invention
Development and Marketing Unit,
Technology Transfer Center, National
Cancer Institute, 9609 Medical Center
Drive, Mail Stop 9702, Rockville, MD
20850–9702, Tel. 240–276–5515 or
asabaliauskas on DSK3SPTVN1PROD with NOTICES
SUMMARY:
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Email ncitechtransfer@mail.nih.gov. A
signed Confidential Disclosure
Agreement may be required to receive
copies of the patent applications.
SUPPLEMENTARY INFORMATION:
Technology description follows.
Title of invention: Human Monoclonal
Antibodies Targeting Glypican-2 in
Neuroblastoma.
Keywords: Glypican-2, GPC2,
Antibody, Immunotoxin, Recombinant
Immunotoxin, RIT, Chimeric Antigen
Receptor, CAR, Antibody-drug
Conjugate, ADC, bispecific antibody,
neuroblastoma.
Description of Technology:
Neuroblastoma is a rare pediatric cancer
that affects one in every hundred
thousand children under the age of
fifteen in the United States. Current
standards of care are chemotherapy and
surgery, followed by stem-cell
treatments, radiation and antiganglioside antibody therapy, which
yield an average three-year survival rate
of 10–45%. This demonstrates a need
for more effective therapies.
Glypican-2 (GPC2) is a cell surface
protein that has been shown to be
preferentially expressed on numerous
pediatric cancers, including
neuroblastoma. Due to this preferential
expression, GPC2 represents a potential
candidate for targeted therapy.
Researchers at the National Cancer
Institute’s Laboratory of Molecular
Biology (NCI LMB) have developed and
isolated several single domain
monoclonal human antibodies against
GPC2. This technology covers the naked
GPC2 antibodies as well as their use as
targeting domains in recombinant
immunotoxins (RITs) and chimeric
antigen receptors (CARs). RITs (using
clones LH1, LH4, or LH7) and CARs
(using LH7) have shown specific killing
activity against GPC2-expressing cells,
suggesting that these candidates may be
further developed as therapeutics.
The technology has been validated
with in-vitro studies (human anti-GPC2
RITs and CARs can bind to, and kill,
GPC2-positive tumor cells) and the
researchers are currently developing
mouse models to further develop GPC2targeted therapies.
Potential Commercial Applications:
—Therapeutic applications include:
Unconjugated antibodies, and use as
targeting moieties for
immunoconjugates such as CARs,
ADCs, immunotoxins, and bispecific
antibodies
—Diagnostic agent for detecting and
monitoring target-expressing
malignancies
Value Proposition:
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—First to market potential—No current
clinical trials with GPC2-targeted
therapies
—Human antibody with high specificity
and binding to targets results in less
non-specific cell killing, therefore
fewer potential side-effects for the
patient
—Small size of single domain
antibodies enhances stability,
solubility, and target recognition
Development Stage: In-vitro.
Inventor(s): Mitchell Ho (NCI), et al.
Intellectual Property: US Provisional
Application 62/369,861 (HHS Reference
No. E–211–2016/0–US–01) filed August
2, 2016, entitled ‘‘Human Monoclonal
Antibodies Targeting Glypican-2 in
Neuroblastoma.’’
Collaboration Opportunity:
Researchers at the NCI seek parties
interested in licensing or co-developing
GPC2 antibodies and/or conjugates.
Contact Information: Requests for
copies of the patent application or
inquiries about licensing, research
collaborations, and co-development
opportunities should be sent to John D.
Hewes, Ph.D., email: john.hewes@
nih.gov.
Dated: August 8, 2016.
John D. Hewes,
Technology Transfer Specialist, Technology
Transfer Center, National Cancer Institute.
[FR Doc. 2016–19419 Filed 8–15–16; 8:45 am]
BILLING CODE 4140–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Substance Abuse and Mental Health
Services Administration
Advisory Committee for Women’s
Services; Notice of Meeting
Pursuant to Public Law 92–463,
notice is hereby given of a meeting of
the Substance Abuse and Mental Health
Services Administration’s (SAMHSA)
Advisory Committee for Women’s
Services (ACWS) on August 24, 2016.
The meeting will include discussions
on child welfare and substance use
disorders among families; improving the
health of women and girls; recoveryoriented systems of care and what they
mean for women; accountable health
communities and how they relate to
behavioral health; and a conversation
with the SAMHSA Deputy of
Operations and the Chief of Staff.
The meeting is open to the public and
will be held at SAMHSA, 5600 Fishers
Lane, Rockville, MD 20857, in
Conference Room 5N76. Attendance by
the public will be limited to space
available. Interested persons may
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Federal Register / Vol. 81, No. 158 / Tuesday, August 16, 2016 / Notices
present data, information, or views,
orally or in writing, on issues pending
before the committee. Written
submissions should be forwarded to the
contact person (below) on or before
August 19, 2016. Oral presentations
from the public will be scheduled at the
conclusion of the meeting. Individuals
interested in making oral presentations
are encouraged to notify the contact
person on or before August 19, 2016.
Five minutes will be allotted for each
presentation.
The meeting may be accesed via
telephone. To attend on site, obtain the
call-in number and access code, submit
written or brief oral comments, or
request special accommodations for
persons with disabilities, please register
on-line at https://nac.samhsa.gov/
Registration/meetingsRegistration.aspx,
or communicate with SAMHSA’s
Designated Federal Officer, Ms. Nadine
Benton (see contact information below).
Substantive meeting information and
a roster of Committee members may be
obtained either by accessing the
SAMHSA Committees’ Web site https://
www.samhsa.gov/about-us/advisorycouncils/advisory-committee-womensservices-acws or by contacting Ms.
Benton.
Committee Name: Substance Abuse and
Mental Health Services Administration
Advisory Committee for Women’s Services
(ACWS).
Date/Time/Type: Wednesday, August 24,
2016, from: 9:00 a.m. to 5:00 p.m. EDT, open.
Place: SAMHSA, 5600 Fishers Lane,
Conference Room 5N76, Rockville, Maryland
20857.
Contact: Nadine Benton, Designated
Federal Official, SAMHSA’s Advisory
Committee for Women’s Services, 5600
Fishers Lane, Rockville, Maryland 20857,
Telephone: (240) 276–0127, Fax: (240) 276–
2252, Email: nadine.benton@samhsa.hhs.gov.
Summer King,
Statistician, Substance Abuse and Mental
Health, Services Administration.
[FR Doc. 2016–19422 Filed 8–15–16; 8:45 am]
BILLING CODE 4162–20–P
DEPARTMENT OF HOMELAND
SECURITY
Coast Guard
asabaliauskas on DSK3SPTVN1PROD with NOTICES
[Docket No. USCG–2016–0437]
Update to Alternative Planning Criteria
(APC) National Guidelines
Coast Guard, DHS.
Extension of comment period
and notice of public meeting.
AGENCY:
ACTION:
Representatives from the U.S.
Coast Guard’s Office of Marine
SUMMARY:
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Environmental Response Policy and
Seventeenth District will meet on
September 21, 2016, in Anchorage,
Alaska. The meeting will be used as an
opportunity to discuss Alternative
Planning Criteria (APC) as they relate to
oil spill preparedness pursuant to vessel
response plan requirements. The
meeting will be open to the public. In
addition, the comment period for the
notice published May 27, 2016, is
extended.
DATES: The comment period for the
notice published May 27, 2016 (81 FR
33685) is extended. Comments and
related material must be submitted on or
before Friday, September 23, 2016. The
Coast Guard will meet Wednesday,
September 21, 2016, from 8:30 a.m. to
3:00 p.m. Please note that the meeting
may close early if all comments have
been heard.
ADDRESSES: The meeting will be held in
the Robert Atwood Room (Room 104) on
the first floor of the Robert B. Atwood
Building, 550 W. 7th Avenue,
Anchorage, AK 99501. Parking will be
available in the adjacent Lilly Pacillo
Parking Garage. Parking tickets can be
validated at the Atwood Building’s
Security Desk.
For information on facilities or
services for individuals with
disabilities, or to request special
assistance at the meeting, contact the
person listed in FOR FURTHER
INFORMATION CONTACT below, as soon as
possible.
To view the APC Guidelines, as well
as public comments and any documents
mentioned in this notice, go to https://
www.regulations.gov and type ‘‘USCG–
2016–0437,’’ and click ‘‘Search.’’ Then
click ‘‘Open Docket Folder.’’
FOR FURTHER INFORMATION CONTACT: CDR
Scott Stoermer, USCG Headquarters,
2703 Martin Luther King Jr. Ave SE.,
Stop 7516, Washington, DC 20593,
scott.a.stoermer@uscg.mil, (202) 372–
2234.
SUPPLEMENTARY INFORMATION: This
public meeting is part of the public
comment period already announced
regarding the draft National APC Policy
(81 FR 33685). To facilitate public
participation, we are extending the
comment period and holding a public
meeting, and we invite public comment
on the issues as listed in the ‘‘Agenda’’
section below. Comments previously
submitted do not need to be submitted
again.
Submitting Written Comments
If you submit a written comment,
please include the docket number,
indicate the specific material to which
each comment applies, and provide a
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reason for each suggestion or
recommendation.
We encourage you to submit
comments through the Federal
eRulemaking Portal at https://
www.regulations.gov. If your material
cannot be submitted using https://
www.regulations.gov, contact the person
in the FOR FURTHER INFORMATION
CONTACT section of this document for
alternate instructions. Documents
mentioned in this notice, and all public
comments, are in our online docket at
https://www.regulations.gov and can be
viewed by following that Web site’s
instructions. Additionally, if you go to
the online docket and sign up for email
alerts, you will be notified when
comments are posted or a final rule is
published.
We accept anonymous comments. All
comments received will be posted
without change to https://
www.regulations.gov and will include
any personal information you have
provided. For more about privacy and
the docket, you may review a Privacy
Act notice regarding the Federal Docket
Management System in the March 24,
2005, issue of the Federal Register (70
FR 15086).
Public Meeting
A public comment period will be held
during the meeting on September 21,
2016, from 12:00 p.m. to 3:00 p.m.
Speakers are requested to limit their
comments to 3 minutes. Please note that
the public comment period may end
before the time indicated, following the
last call for comments. Contact the
individual listed below to pre-register as
a speaker. Pre-registration is not
required to speak at the meeting as
attendees will be able to note their
desire to speak via the on-site meeting
attendance/registration form. Written
comments may also be brought to the
meeting and will be included as part of
the docket. Written comments
submitted to the docket via https://
www.regulations.gov do not need to be
brought to the meeting.
The U.S. Coast Guard Office of Marine
Environmental Response Policy is
developing national-level policy to
clarify APC submissions and processes
pursuant to Title 33 Code of Federal
Regulations, Part 155.1065 and
155.5067. While not a regulatory or rulemaking activity, the Coast Guard is
aware of the impact of the policy related
to APC and its critical role in tank and
non-tank vessel response preparedness.
The goals of this public meeting are to:
(1) Inform public entities of the status of
Alternative Planning Criteria policy; (2)
Inform public entities of the comments
from earlier comment period(s); (3)
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Agencies
[Federal Register Volume 81, Number 158 (Tuesday, August 16, 2016)]
[Notices]
[Pages 54583-54584]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2016-19422]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
Substance Abuse and Mental Health Services Administration
Advisory Committee for Women's Services; Notice of Meeting
Pursuant to Public Law 92-463, notice is hereby given of a meeting
of the Substance Abuse and Mental Health Services Administration's
(SAMHSA) Advisory Committee for Women's Services (ACWS) on August 24,
2016.
The meeting will include discussions on child welfare and substance
use disorders among families; improving the health of women and girls;
recovery-oriented systems of care and what they mean for women;
accountable health communities and how they relate to behavioral
health; and a conversation with the SAMHSA Deputy of Operations and the
Chief of Staff.
The meeting is open to the public and will be held at SAMHSA, 5600
Fishers Lane, Rockville, MD 20857, in Conference Room 5N76. Attendance
by the public will be limited to space available. Interested persons
may
[[Page 54584]]
present data, information, or views, orally or in writing, on issues
pending before the committee. Written submissions should be forwarded
to the contact person (below) on or before August 19, 2016. Oral
presentations from the public will be scheduled at the conclusion of
the meeting. Individuals interested in making oral presentations are
encouraged to notify the contact person on or before August 19, 2016.
Five minutes will be allotted for each presentation.
The meeting may be accesed via telephone. To attend on site, obtain
the call-in number and access code, submit written or brief oral
comments, or request special accommodations for persons with
disabilities, please register on-line at https://nac.samhsa.gov/Registration/meetingsRegistration.aspx, or communicate with SAMHSA's
Designated Federal Officer, Ms. Nadine Benton (see contact information
below).
Substantive meeting information and a roster of Committee members
may be obtained either by accessing the SAMHSA Committees' Web site
https://www.samhsa.gov/about-us/advisory-councils/advisory-committee-womens-services-acws or by contacting Ms. Benton.
Committee Name: Substance Abuse and Mental Health Services
Administration Advisory Committee for Women's Services (ACWS).
Date/Time/Type: Wednesday, August 24, 2016, from: 9:00 a.m. to
5:00 p.m. EDT, open.
Place: SAMHSA, 5600 Fishers Lane, Conference Room 5N76,
Rockville, Maryland 20857.
Contact: Nadine Benton, Designated Federal Official, SAMHSA's
Advisory Committee for Women's Services, 5600 Fishers Lane,
Rockville, Maryland 20857, Telephone: (240) 276-0127, Fax: (240)
276-2252, Email: nadine.benton@samhsa.hhs.gov.
Summer King,
Statistician, Substance Abuse and Mental Health, Services
Administration.
[FR Doc. 2016-19422 Filed 8-15-16; 8:45 am]
BILLING CODE 4162-20-P