Technology Innovation Program (TIP) Seeks White Papers, 76339-76341 [E8-29745]

Download as PDF Federal Register / Vol. 73, No. 242 / Tuesday, December 16, 2008 / Notices Dated: December 8, 2008. Patrick Gallagher, Deputy Director. [FR Doc. E8–29746 Filed 12–15–08; 8:45 am] BILLING CODE 3510–13–P DEPARTMENT OF COMMERCE National Institute of Standards and Technology Technology Innovation Program (TIP) Seeks White Papers AGENCY: National Institute of Standards and Technology (NIST), Department of Commerce. ACTION: Notice. sroberts on PROD1PC70 with NOTICES SUMMARY: The National Institute of Standards and Technology’s (NIST) Technology Innovation Program (TIP) announces that it is seeking white papers from any interested party, including academia; federal, state, and local governments; industry; national laboratories; and professional organizations/societies. White papers will be used to identify and select areas of critical national need to be addressed in future TIP competitions. DATES: The due dates for submission of white papers are January 15, 2009, March 9, 2009, May 11, 2009, and July 13, 2009. ADDRESSES: White papers must be submitted to TIP as follows: Paper submission: Send to National Institute of Standards and Technology, Technology Innovation Program, 100 Bureau Drive, Stop 4750, Gaithersburg, MD 20899–4750. Attention: Critical National Needs Ideas. Electronic (e-mail) submission: tipwhitepaper@nist.gov. FOR FURTHER INFORMATION CONTACT: Thomas Wiggins at 301–975–5416 or by e-mail at thomas.wiggins@nist.gov. SUPPLEMENTARY INFORMATION: Background Information. The Technology Innovation Program (TIP) at the National Institute of Standards and Technology (NIST) was established for the purpose of assisting U.S. businesses and institutions of higher education or other organizations, such as national laboratories and nonprofit research institutions, to support, promote, and accelerate innovation in the United States through high-risk, high-reward research in areas of Critical National Need. The TIP statutory authority is Section 3012 of the America Creating Opportunities to Meaningfully Promote Excellence in Technology, Education, and Science (COMPETES) Act, Pub. L. 110–69 (August 9, 2007), 15 U.S.C.A. VerDate Aug<31>2005 17:09 Dec 15, 2008 Jkt 217001 278n (2008). The TIP implementing regulations are published at 15 CFR Part 296 (73 FR 35913 (June 25, 2008)). TIP holds competitions for funding based on areas of critical national need. TIP identifies and selects topics for areas of critical national need based on input from within NIST, the TIP Advisory Board, the science and technology communities, and from the public. TIP is interested in receiving input on the identification and definition of problems that are sufficiently large in magnitude that they have the potential to inhibit the growth and well-being of our nation today. This announcement explains the requirements and process for submitting white papers to TIP by interested parties. White papers from experts in our sister federal agencies are welcomed and also valuable, and will enable TIP to complement the efforts of other mission agencies and avoid duplication of their efforts, as well as leverage resources to benefit the nation. The key concepts, enumerated below, are the foundation of TIP and should form the basis of an effective white paper: a. An area of critical national need means an area that justifies government attention because the magnitude of the problem is large and the associated societal challenges that need to be overcome are not being addressed, but could be addressed through high-risk, high-reward research. b. A societal challenge is a problem or issue confronted by society that when not addressed could negatively affect the overall function and quality of life of the Nation, and as such, justifies government action. A societal challenge is associated with barriers preventing the successful development of solutions to the area of critical national need. TIP’s mission is to tackle the technical issues that can be addressed through high-risk, high-reward research. The results of the high-risk, high-reward research should have the potential for transformational results. c. A transformational result is a potential project outcome that enables disruptive changes over and above current methods and strategies. Transformational results have the potential to radically improve our understanding of systems and technologies, challenging the status quo of research approaches and applications. The white papers are expected to contain: A description of an area of critical national need and the associated societal challenge(s) (what is the problem, why is it a problem, and why is it challenging), why government PO 00000 Frm 00010 Fmt 4703 Sfmt 4703 76339 support is needed, and what could happen if that support is not provided in the proposed timeframe, and a high level discussion of potential technical solutions and an indication of the types of entities or groups who might be interested in developing proposal submissions to fund these solutions. Do not include ideas for specific proposals in the white paper. White papers must not contain proprietary information. Information contained in these white papers will be considered and combined with information from other resources— including the vision of the Administration, NIST, other government agencies, technical communities, the TIP Advisory Board, and other stakeholders—to select the scope of future competitions and to shape TIP’s collaborative outreach. White papers are a valuable resource that adds to TIP’s understanding of the significance and scope of critical national needs and associated societal challenges. For detailed instructions on how to prepare and submit white papers, refer to ‘‘A Guide for Preparing and Submitting White Papers on Areas of Critical National Need.’’ The Guide is available on the TIP Web site at https://www.nist.gov/tip/ guide_for_white_papers.pdf. In this call for white papers, TIP is seeking information in all areas of critical national need, but also seeks information to assist TIP in further defining several topic areas under development. White papers that address any of the following areas may further develop the definition and scope of the critical national need suggested by these topic areas, and should additionally identify and explain specific societal challenges within these critical national need areas that require a technical solution. White papers may discuss any critical national need area of interest to the submitter, or may address any of the following topic areas: Civil Infrastructure: Civil infrastructure constitutes the basic fabric of the world in which we live and work. It is the combination of fundamental systems that support a community, region, or country. The civil infrastructure includes systems for transportation (airport facilities, roads, bridges, rail, waterway locks); and systems for water distribution and flood control (water distribution systems, storm and waste water collection, dams, and levees). New construction approaches and materials to improve the infrastructure and for mitigating the expense of repairing or replacing existing infrastructure appear to be areas with the potential for specific societal E:\FR\FM\16DEN1.SGM 16DEN1 sroberts on PROD1PC70 with NOTICES 76340 Federal Register / Vol. 73, No. 242 / Tuesday, December 16, 2008 / Notices challenges within this area of critical national need. Examples could include challenges such as: advanced materials for repair and rehabilitation of existing infrastructure, advanced inspection and monitoring technologies that assist public safety officials in determining the condition of structures, or areas of sustainability of infrastructure construction. Complex networks and complex systems: Society is increasingly dependent on complex networks like those used for energy delivery, telecommunication, transportation, and finance over which we have very imperfect control. No single organization and no collection of organizations have the ability to effectively control these multi-scale, distributed, highly interactive networks. Complex network theory will also be important in modeling neural systems, molecular physiological response to disease, and environmental systems. The current technical and mathematical methodologies that underpin our ability to simulate and model physical systems are unable to predict and control the behavior of complex systems. Stability and control of these networks can have far reaching consequences to our quality of life. Examples could include challenges such as: theoretical advances and/or proof-of-concept applications; or capabilities that can potentially address and advance the use of complex network analyses in the following areas—sustainable manufacturing models, resource management and environmental impacts (energy, water, agriculture), intelligent transportation systems, biological systems, communications networks, security systems, personalized healthcare, and others. Energy: From agriculture to manufacturing, all endeavors require energy as input. Escalating energy demands throughout the world can lead to national security challenges, financially challenge national economies, and contribute to environmental alterations. Although heavily supported projects exist in energy research, there remain technical roadblocks that affect full deployment of new and emerging energy technologies. Examples could include challenges such as: technologies for improved manufacturing of critical components for alternative energy production; replacement of fossil-fuel derived fuels with non-food, renewably produced fuels; or improved technologies for stable connections of many power sources to the electrical grid. VerDate Aug<31>2005 17:09 Dec 15, 2008 Jkt 217001 Ensuring Future Water Supply: As the Nation’s population and economy grow, greater demands are being placed on freshwater resources. At the same time, temporary or permanent drought conditions and water access rights affect regional freshwater availability. Water needs threaten to outstrip available freshwater, now and in the future. Water quality, both in terms of decontamination and disinfection of water supplies, is also being pressured by emerging contaminants that must either be removed from distributed water or converted to harmless forms of waste. Food contaminations are often traced back to water contaminations, either in the field or in processing. Municipal waste streams and irrigation runoff waste resources that are not recovered. Examples could include challenges such as: means to provide future fresh water supplies without undue consumption of energy resources; means that determine and assure the safety of water and food from waterborne contamination; or means to economically recover resources from wastewater streams and lower the energy cost of producing freshwater and potable water from marginalized water resources. Manufacturing: Manufacturing is a vital part of our nation’s economy, which now is facing increasing global competitiveness challenges, regulations and controls over environmental and resource issues, and other economic pressures. Technical advances have at times been able to address productivity and other issues, but the recent pressures on the manufacturing community have hindered their ability to focus the necessary resources on longer term solutions that could lead to economic growth in this sector which the nation needs. Examples could include challenges such as: manufacturing systems that have shorter innovation cycles, more flexibility, and are rapidly reconfigurable; accelerating commodization of next generation, highperformance materials, such as nanomaterials, composites, and alloys to specification, in a consistent, efficient and effective manner; or life cycle assessment tools, an aid toward sustainable manufacturing; and better robotics solutions. Nanomaterials/nanotechnology: The unique properties of nanomaterials provide extraordinary promise. There is a need for greater understanding and solutions to overcome the barriers associated with manufacturing nanomaterials and their incorporation into products, while maintaining the PO 00000 Frm 00011 Fmt 4703 Sfmt 4703 unique functionality of the nanomaterial. Although many processes are achievable in the laboratory, the scale-up to industrial production without compromising the quality of the produced material can be highly problematic. Examples could include challenges such as: methods required for manufacturing nanomaterials with prespecified functionality and morphology; methods for inspection and real-time monitoring the processing of nanomaterials; or methods for incorporation of nanomaterial into products without compromising the material’s required properties. Personalized Medicine: Healthcare spending per capita in the United States is high and rising and currently approved drugs work only in a fraction of the population. Doctors are unable to select optimal drug treatments and dosages based on the patient’s unique genetics, physiology, and metabolic processes, resulting in a trial and error component in treatment. As a consequence, significant expenditures go for drugs that are ineffective on subsets of patients, and a clearer understanding of which patients may suffer side effects from prescribed medicine is lacking. The key to patient response lies in greater understanding of both genetic variability and environmental influences on disease mechanisms. Examples could include challenges such as: cost effective advanced tools and techniques for genomics and proteomics research that provide greater understanding of complex biological systems, biomarker identification, and targeted drug and vaccine delivery systems; improved and low cost diagnostic and therapeutic systems; or better methods of integration and analysis of biological data, especially when combined with environmental and patient history data. Sustainable Chemistry: The products and processes created through chemical transformations underpin virtually every facet of our economy today, from healthcare to materials to energy. Many industrial-scale chemical processes, however, can have significant negative impacts on the environment that require costly waste prevention controls. These chemical processes also can pose safety risks to human health that might be mitigated through new chemicals. In addition, many processes are highly energy intensive which contributes to increasing costs. Sustainable chemistry seeks to lessen such impacts by the use of safer materials in chemical processes, by substitution of new products with similar properties to existing products, E:\FR\FM\16DEN1.SGM 16DEN1 Federal Register / Vol. 73, No. 242 / Tuesday, December 16, 2008 / Notices and by reducing the energy intensity of the unit operations within the chemical manufacturing industry. Examples could include challenges such as: novel, advanced process chemistries and technologies that are inherently safer and cleaner, while creating products and processes with attributes superior to conventional methods; advanced chemical separations; and energy and material efficient technologies for chemical processing. Dated: December 11, 2008. Patrick Gallagher, Deputy Director. [FR Doc. E8–29745 Filed 12–15–08; 8:45 am] Rowena.forest@noaa.gov, P.O. Box 159 Olema, CA 94950, (415) 663–0314 x105. SUPPLEMENTARY INFORMATION: NOAA established the Advisory Council for Cordell Bank in 2002. The Council has members representing education, research, conservation, maritime activity, and community-at-large. The government seats are held by representatives from the National Marine Fisheries Service, the United States Coast Guard, and the managers of the Gulf of the Farallones, Monterey Bay and Channel Islands National Marine Sanctuaries. The Council holds four regular meetings per year, and one annual retreat. Authority: 16 U.S.C. Sections 1431, et seq. BILLING CODE 3510–13–P (Federal Domestic Assistance Catalog Number 11.429 Marine Sanctuary Program) DEPARTMENT OF COMMERCE Dated: December 8, 2008. Daniel J. Basta, Director, Office of National Marine Sanctuaries, National Ocean Services, National Oceanic and Atmospheric Administration. [FR Doc. E8–29649 Filed 12–15–08; 8:45 am] National Oceanic and Atmospheric Administration Availability of Seats for the Cordell Bank National Marine Sanctuary Advisory Council BILLING CODE 3510–NK–M Office of National Marine Sanctuaries (ONMS), National Ocean Service (NOS), National Oceanic and Atmospheric Administration, Department of Commerce (DOC). ACTION: Notice and request for applications. sroberts on PROD1PC70 with NOTICES AGENCY: DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration (NOAA) [Docket No. 0811251527–81528–01] SUMMARY: The ONMS is seeking applicants for the following vacant seats on the Cordell Bank National Marine Sanctuary Advisory Council (Council): Conservation Alternate and Primary, Maritime Activities Alternate and Primary. Applicants are chosen based upon their particular expertise and experience in relation to the seat for which they are applying; community and professional affiliations; philosophy regarding the protection and management of marine resources; and possibly the length of residence in the area affected by the Sanctuary. Applicants who are chosen as members should expect to serve 2–3 year terms, pursuant to the Council’s Charter. DATES: Applications are due by January 30th, 2009. ADDRESSES: Application kits may be obtained on the Cordell Bank Web site at: https://cordellbank.noaa.gov, and from Cordell Bank National Marine Sanctuary, Rowena Forest, P.O. Box 159, Olema, CA 94950. Completed applications should be sent to the above mailing address or faxed to (415) 663– 0315. FOR FURTHER INFORMATION CONTACT: Rowena Forest/CBNMS, VerDate Aug<31>2005 17:09 Dec 15, 2008 Jkt 217001 RIN 0648–ZC03 NOAA Bay Watershed Education and Training (B–WET) Program AGENCY: Office of Education (OED), Office of the Under Secretary (USEC), National Oceanic and Atmospheric Administration (NOAA), Commerce. ACTION: Notice of funding availability. SUMMARY: NOAA B–WET is an environmental education program that promotes locally relevant, experiential learning in the K–12 environment. Funded projects provide meaningful watershed educational experiences for students, related professional development for teachers, and helps to support regional education and environmental priorities in the Pacific Northwest, the northern Gulf of Mexico and New England. DATES: Proposals must be submitted by 5 p.m. Eastern Time on January 26, 2009. See Sections IV C and F of this announcement for more information on submission requirements. ADDRESSES: Electronic application packages are strongly encouraged and are available at: https://www.grants.gov/. Paper application packages are available PO 00000 Frm 00012 Fmt 4703 Sfmt 4703 76341 on the NOAA Grants Management Web site at: https://www.ago.noaa.gov/ago/ grants/forms.cfm. If the applicant has difficulty accessing Grants.gov or downloading the required forms from the NOAA Web site, the applicant should contact: Bronwen Rice, B–WET National Coordinator, by phone at 202– 482–6797 or e-mail at bronwen.rice@noaa.gov. Grants.gov requires applicants to register with the system prior to submitting an application. This registration process can take several weeks and involves multiple steps. In order to allow sufficient time for this process, you should register as soon as you decide to apply, even if you are not yet ready to submit your proposal. If an applicant has problems downloading the application forms from Grants.gov, contact Grants.gov Customer Support at 1–800–518–4726 or support@grants.gov. For non-Windows computer systems, please see https://www.grants.gov/ MacSupport for information on how to download and submit an application through Grants.gov. FOR FURTHER INFORMATION CONTACT: For the Pacific Northwest, please contact Seaberry Nachbar at 831–647–4201, or via e-mail at seaberry.nachbar@noaa.gov. For the northern Gulf of Mexico, Stephanie Bennett at 808–522–7481, or via e-mail at stephanie.bennett@noaa.gov. For New England, Shannon Sprague, at 410–267–5664, or via e-mail at shannon.sprague@noaa.gov. Questions about this opportunity may also be directed to Bronwen Rice, B–WET National Coordinator, by phone at 202– 482–6797 or e-mail at bronwen.rice@noaa.gov. The NOAA Bay Watershed Education and Training (B–WET) Program is an environmental education program that supports experiential learning through local competitive grant awards in specific geographic regions. Prior to 2008 NOAA B–WET Programs were established for the Chesapeake Bay, California, and the Hawaiian Islands. As of 2008, three new programs are in place in New England, the northern Gulf of Mexico, and the Pacific Northwest. In FY09, it is anticipated that funds will be available for each of these three regions. Proposals are currently being solicited from the Pacific Northwest region, the northern Gulf of Mexico region, and the New England region. For the purposes of this solicitation, these three regions are defined as follows: a. Pacific Northwest—the states of Oregon and Washington; SUPPLEMENTARY INFORMATION: E:\FR\FM\16DEN1.SGM 16DEN1

Agencies

[Federal Register Volume 73, Number 242 (Tuesday, December 16, 2008)]
[Notices]
[Pages 76339-76341]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E8-29745]


-----------------------------------------------------------------------

DEPARTMENT OF COMMERCE

National Institute of Standards and Technology


Technology Innovation Program (TIP) Seeks White Papers

AGENCY: National Institute of Standards and Technology (NIST), 
Department of Commerce.

ACTION: Notice.

-----------------------------------------------------------------------

SUMMARY: The National Institute of Standards and Technology's (NIST) 
Technology Innovation Program (TIP) announces that it is seeking white 
papers from any interested party, including academia; federal, state, 
and local governments; industry; national laboratories; and 
professional organizations/societies. White papers will be used to 
identify and select areas of critical national need to be addressed in 
future TIP competitions.

DATES: The due dates for submission of white papers are January 15, 
2009, March 9, 2009, May 11, 2009, and July 13, 2009.

ADDRESSES: White papers must be submitted to TIP as follows:
    Paper submission: Send to National Institute of Standards and 
Technology, Technology Innovation Program, 100 Bureau Drive, Stop 4750, 
Gaithersburg, MD 20899-4750. Attention: Critical National Needs Ideas.
    Electronic (e-mail) submission: tipwhitepaper@nist.gov.

FOR FURTHER INFORMATION CONTACT: Thomas Wiggins at 301-975-5416 or by 
e-mail at thomas.wiggins@nist.gov.

SUPPLEMENTARY INFORMATION:
    Background Information. The Technology Innovation Program (TIP) at 
the National Institute of Standards and Technology (NIST) was 
established for the purpose of assisting U.S. businesses and 
institutions of higher education or other organizations, such as 
national laboratories and nonprofit research institutions, to support, 
promote, and accelerate innovation in the United States through high-
risk, high-reward research in areas of Critical National Need. The TIP 
statutory authority is Section 3012 of the America Creating 
Opportunities to Meaningfully Promote Excellence in Technology, 
Education, and Science (COMPETES) Act, Pub. L. 110-69 (August 9, 2007), 
15 U.S.C.A. 278n (2008). The TIP implementing regulations are published 
at 15 CFR Part 296 (73 FR 35913 (June 25, 2008)).
    TIP holds competitions for funding based on areas of critical 
national need. TIP identifies and selects topics for areas of critical 
national need based on input from within NIST, the TIP Advisory Board, 
the science and technology communities, and from the public. TIP is 
interested in receiving input on the identification and definition of 
problems that are sufficiently large in magnitude that they have the 
potential to inhibit the growth and well-being of our nation today. 
This announcement explains the requirements and process for submitting 
white papers to TIP by interested parties. White papers from experts in 
our sister federal agencies are welcomed and also valuable, and will 
enable TIP to complement the efforts of other mission agencies and 
avoid duplication of their efforts, as well as leverage resources to 
benefit the nation.
    The key concepts, enumerated below, are the foundation of TIP and 
should form the basis of an effective white paper:
    a. An area of critical national need means an area that justifies 
government attention because the magnitude of the problem is large and 
the associated societal challenges that need to be overcome are not 
being addressed, but could be addressed through high-risk, high-reward 
research.
    b. A societal challenge is a problem or issue confronted by society 
that when not addressed could negatively affect the overall function 
and quality of life of the Nation, and as such, justifies government 
action. A societal challenge is associated with barriers preventing the 
successful development of solutions to the area of critical national 
need. TIP's mission is to tackle the technical issues that can be 
addressed through high-risk, high-reward research. The results of the 
high-risk, high-reward research should have the potential for 
transformational results.
    c. A transformational result is a potential project outcome that 
enables disruptive changes over and above current methods and 
strategies. Transformational results have the potential to radically 
improve our understanding of systems and technologies, challenging the 
status quo of research approaches and applications.
    The white papers are expected to contain: A description of an area 
of critical national need and the associated societal challenge(s) 
(what is the problem, why is it a problem, and why is it challenging), 
why government support is needed, and what could happen if that support 
is not provided in the proposed timeframe, and a high level discussion 
of potential technical solutions and an indication of the types of 
entities or groups who might be interested in developing proposal 
submissions to fund these solutions. Do not include ideas for specific 
proposals in the white paper.
    White papers must not contain proprietary information.
    Information contained in these white papers will be considered and 
combined with information from other resources--including the vision of 
the Administration, NIST, other government agencies, technical 
communities, the TIP Advisory Board, and other stakeholders--to select 
the scope of future competitions and to shape TIP's collaborative 
outreach. White papers are a valuable resource that adds to TIP's 
understanding of the significance and scope of critical national needs 
and associated societal challenges.
    For detailed instructions on how to prepare and submit white 
papers, refer to ``A Guide for Preparing and Submitting White Papers on 
Areas of Critical National Need.'' The Guide is available on the TIP 
Web site at https://www.nist.gov/tip/guide_for_white_papers.pdf.
    In this call for white papers, TIP is seeking information in all 
areas of critical national need, but also seeks information to assist 
TIP in further defining several topic areas under development. White 
papers that address any of the following areas may further develop the 
definition and scope of the critical national need suggested by these 
topic areas, and should additionally identify and explain specific 
societal challenges within these critical national need areas that 
require a technical solution. White papers may discuss any critical 
national need area of interest to the submitter, or may address any of 
the following topic areas:
    Civil Infrastructure: Civil infrastructure constitutes the basic 
fabric of the world in which we live and work. It is the combination of 
fundamental systems that support a community, region, or country. The 
civil infrastructure includes systems for transportation (airport 
facilities, roads, bridges, rail, waterway locks); and systems for 
water distribution and flood control (water distribution systems, storm 
and waste water collection, dams, and levees). New construction 
approaches and materials to improve the infrastructure and for 
mitigating the expense of repairing or replacing existing 
infrastructure appear to be areas with the potential for specific 
societal

[[Page 76340]]

challenges within this area of critical national need.
    Examples could include challenges such as: advanced materials for 
repair and rehabilitation of existing infrastructure, advanced 
inspection and monitoring technologies that assist public safety 
officials in determining the condition of structures, or areas of 
sustainability of infrastructure construction.
    Complex networks and complex systems: Society is increasingly 
dependent on complex networks like those used for energy delivery, 
telecommunication, transportation, and finance over which we have very 
imperfect control. No single organization and no collection of 
organizations have the ability to effectively control these multi-
scale, distributed, highly interactive networks. Complex network theory 
will also be important in modeling neural systems, molecular 
physiological response to disease, and environmental systems. The 
current technical and mathematical methodologies that underpin our 
ability to simulate and model physical systems are unable to predict 
and control the behavior of complex systems. Stability and control of 
these networks can have far reaching consequences to our quality of 
life.
    Examples could include challenges such as: theoretical advances 
and/or proof-of-concept applications; or capabilities that can 
potentially address and advance the use of complex network analyses in 
the following areas--sustainable manufacturing models, resource 
management and environmental impacts (energy, water, agriculture), 
intelligent transportation systems, biological systems, communications 
networks, security systems, personalized healthcare, and others.
    Energy: From agriculture to manufacturing, all endeavors require 
energy as input. Escalating energy demands throughout the world can 
lead to national security challenges, financially challenge national 
economies, and contribute to environmental alterations. Although 
heavily supported projects exist in energy research, there remain 
technical roadblocks that affect full deployment of new and emerging 
energy technologies.
    Examples could include challenges such as: technologies for 
improved manufacturing of critical components for alternative energy 
production; replacement of fossil-fuel derived fuels with non-food, 
renewably produced fuels; or improved technologies for stable 
connections of many power sources to the electrical grid.
    Ensuring Future Water Supply: As the Nation's population and 
economy grow, greater demands are being placed on freshwater resources. 
At the same time, temporary or permanent drought conditions and water 
access rights affect regional freshwater availability. Water needs 
threaten to outstrip available freshwater, now and in the future. Water 
quality, both in terms of decontamination and disinfection of water 
supplies, is also being pressured by emerging contaminants that must 
either be removed from distributed water or converted to harmless forms 
of waste. Food contaminations are often traced back to water 
contaminations, either in the field or in processing. Municipal waste 
streams and irrigation runoff waste resources that are not recovered.
    Examples could include challenges such as: means to provide future 
fresh water supplies without undue consumption of energy resources; 
means that determine and assure the safety of water and food from 
waterborne contamination; or means to economically recover resources 
from wastewater streams and lower the energy cost of producing 
freshwater and potable water from marginalized water resources.
    Manufacturing: Manufacturing is a vital part of our nation's 
economy, which now is facing increasing global competitiveness 
challenges, regulations and controls over environmental and resource 
issues, and other economic pressures. Technical advances have at times 
been able to address productivity and other issues, but the recent 
pressures on the manufacturing community have hindered their ability to 
focus the necessary resources on longer term solutions that could lead 
to economic growth in this sector which the nation needs.
    Examples could include challenges such as: manufacturing systems 
that have shorter innovation cycles, more flexibility, and are rapidly 
reconfigurable; accelerating commodization of next generation, high-
performance materials, such as nanomaterials, composites, and alloys to 
specification, in a consistent, efficient and effective manner; or life 
cycle assessment tools, an aid toward sustainable manufacturing; and 
better robotics solutions.
    Nanomaterials/nanotechnology: The unique properties of 
nanomaterials provide extraordinary promise. There is a need for 
greater understanding and solutions to overcome the barriers associated 
with manufacturing nanomaterials and their incorporation into products, 
while maintaining the unique functionality of the nanomaterial. 
Although many processes are achievable in the laboratory, the scale-up 
to industrial production without compromising the quality of the 
produced material can be highly problematic.
    Examples could include challenges such as: methods required for 
manufacturing nanomaterials with pre-specified functionality and 
morphology; methods for inspection and real-time monitoring the 
processing of nanomaterials; or methods for incorporation of 
nanomaterial into products without compromising the material's required 
properties.
    Personalized Medicine: Healthcare spending per capita in the United 
States is high and rising and currently approved drugs work only in a 
fraction of the population. Doctors are unable to select optimal drug 
treatments and dosages based on the patient's unique genetics, 
physiology, and metabolic processes, resulting in a trial and error 
component in treatment. As a consequence, significant expenditures go 
for drugs that are ineffective on subsets of patients, and a clearer 
understanding of which patients may suffer side effects from prescribed 
medicine is lacking. The key to patient response lies in greater 
understanding of both genetic variability and environmental influences 
on disease mechanisms.
    Examples could include challenges such as: cost effective advanced 
tools and techniques for genomics and proteomics research that provide 
greater understanding of complex biological systems, biomarker 
identification, and targeted drug and vaccine delivery systems; 
improved and low cost diagnostic and therapeutic systems; or better 
methods of integration and analysis of biological data, especially when 
combined with environmental and patient history data.
    Sustainable Chemistry: The products and processes created through 
chemical transformations underpin virtually every facet of our economy 
today, from healthcare to materials to energy. Many industrial-scale 
chemical processes, however, can have significant negative impacts on 
the environment that require costly waste prevention controls. These 
chemical processes also can pose safety risks to human health that 
might be mitigated through new chemicals. In addition, many processes 
are highly energy intensive which contributes to increasing costs. 
Sustainable chemistry seeks to lessen such impacts by the use of safer 
materials in chemical processes, by substitution of new products with 
similar properties to existing products,

[[Page 76341]]

and by reducing the energy intensity of the unit operations within the 
chemical manufacturing industry.
    Examples could include challenges such as: novel, advanced process 
chemistries and technologies that are inherently safer and cleaner, 
while creating products and processes with attributes superior to 
conventional methods; advanced chemical separations; and energy and 
material efficient technologies for chemical processing.

    Dated: December 11, 2008.
Patrick Gallagher,
Deputy Director.
[FR Doc. E8-29745 Filed 12-15-08; 8:45 am]
BILLING CODE 3510-13-P
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