Proposed Information Collection Activity; Comment Request, 55798-55799 [06-8110]
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55798
Federal Register / Vol. 71, No. 185 / Monday, September 25, 2006 / Notices
ESTIMATED ANNUALIZED BURDEN HOURS
BILLING CODE 4163–18–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Administration for Children and
Families
Proposed Information Collection
Activity; Comment Request
Proposed Projects
Title: DHHS/ACF/ASPE/DOL
Enhanced Services for the Hard-toEmploy Demonstration and Evaluation:
Rhode Island 15-Month Survey
Amendment.
OMB No. 0970–0276.
Description: The Enhanced Services
for the Hard-to-Employe Demonstration
and Evaluation Project (HtE) seeks to
learn what works in this area to date
and is explicitly designed to build on
past research by rigorously testing a
wide variety of approaches to promote
employment and improve family
functioning and child well-being. The
1
1
10/60
1.10
5,180
4,300
3,000
4,000
HtE project is designed to help
Temporary Assistance for Needy
Families (TANF) recipients, former
TANF recipients, or low-income parents
who are hard-to-employ. The project is
sponsored by the Office of Planning,
Research and Evaluation (OPRE) of the
Administration for Children and
Families (ACF), the Office of the
Assistant Secretary for Planning and
Evaluation (ASPE) in the U.S.
Department of Health and Human
Services (HHS), and the U.S.
Department of Labor (DOL).
The evaluation involves an
experimental, random assignment
design in four sites, testing a diverse set
of strategies to promote employment for
low-income parents who face serious
obstacles to employment. The four
include: (1) Intensive care management
to facilitate the use of evidence-based
treatment for major depression among
parents receiving Medicaid in Rhode
Island; (2) job readiness training,
worksite placements, job coaching, job
development and other training
opportunities for recent parolees in New
York City; (3) pre-employment services
and transitional employment for longterm TANF participants in Philadelphia;
and (4) home- and center-based care,
enhanced with self-sufficiency services,
Number of responses per
respondent
13,333
300
1. Screening interview only .........................................................................................................
2. Screener, family, and sample person interviews only ............................................................
3. Screener, family, and sample person interviews and MEC examination (including pilot
studies) .....................................................................................................................................
4. Second dietary recall interview ...............................................................................................
5. Telephone Interview (FCBS) ...................................................................................................
6. Follow-up, special studies, and tests of procedures ...............................................................
Dated: September 19, 2006.
Joan F. Karr,
Acting Reports Clearance Officer, Centers for
Disease Control and Prevention.
[FR Doc. 06–8164 Filed 9–22–06; 8:45 am]
Average burden per response
(hours)
Number of respondents per
year
Burden category
1
1
1
1
5.9
30/60
20/60
5.9
for low-income families who have
young children or are expecting in
Kansas and Missouri.
Materials for follow-up surveys for
each of these sites were previously
submitted to OMB and were approved.
The purpose of this submission is to add
physiological measures to the follow-up
effort to the Rhode Island study.
Respondents: The respondents to this
component of the Rhode Island followup survey will be low-income parents
and their children from the Rhode
Island site currently participating in the
HtE Project. As described in the prior
OMB submission, these parents are
Medicaid recipients between the ages of
18 and 45 receiving Medicaid through
the managed care provider United
Behavioral Health (UBH) in Rhode
Island who meet study criteria with
regard to their risk for depression.
Children are the biological, adopted,
and step-children of these parents,
between the ages of 1 and 18 years of
age.
The annual burden estimates are
detailed below, and the substantive
content of each component will be
detailed in the supporting statement
attached to the forthcoming 30-day
notice.
ANNUAL BURDEN ESTIMATES
Number of respondents
Instrument
Number of responses per
respondent
Average burden hours per response
400
160
242
8
8
8
5 minutes or .08 hrs ..............
5 minutes or .08 hrs ..............
5 minutes or .08 hrs ..............
rwilkins on PROD1PC63 with NOTICES
RI 15-month, parent physiological component .......................
RI 15-month young child physiological component ................
RI 15-month youth physiological component ..........................
Estimated Total Annual Burden
Hours: 534.65.
In compliance with the requirements
of Section 3506(c)(2)(A) of the
Paperwork Reduction Act of 1995, the
Administration for Children and
Families is soliciting public comment
on the specific aspects of the
information collection described above.
VerDate Aug<31>2005
17:46 Sep 22, 2006
Jkt 208001
Copies of the proposed collection of
information can be obtained and
comments may be forwarded by writing
to the Administration for Children and
Families, Office of Administration,
Office of Information Services, 370
L’Enfant Promenade, SW., Washington,
DC 20447, Attn: ACF Reports Clearance
Officer. E-mail address:
PO 00000
Frm 00025
Fmt 4703
Sfmt 4703
Total burden
hours
266.66
106.66
161.33
infocollection@acf.hhs.gov. All requests
should be identified by the title of the
information collection.
The Department specifically requests
comments on: (a) Whether the proposed
collection of information is necessary
for the proper performance of the
functions of the agency, including
whether the information shall have
E:\FR\FM\25SEN1.SGM
25SEN1
Federal Register / Vol. 71, No. 185 / Monday, September 25, 2006 / Notices
practical utility; (b) the accuracy of the
agency’s estimate of the burden of the
proposed collection of information; (c)
the quality, utility, and clarity of the
information to be collected; and (d)
ways to minimize the burden of the
collection of information on
respondents, including through the use
of automated collection techniques or
other forms of information technology.
Consideration will be given to
comments and suggestions submitted
within 60 days of this publication.
Dated: September 19, 2006.
Robert Sargis,
Reports Clearance Officer.
[FR Doc. 06–8110 Filed 9–22–06; 8:45 am]
BILLING CODE 4184–01–M
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Food and Drug Administration
[Docket No. 2006E–0031]
Determination of Regulatory Review
Period for Purposes of Patent
Extension; CLOLAR
AGENCY:
Food and Drug Administration,
HHS.
rwilkins on PROD1PC63 with NOTICES
ACTION:
Notice.
SUMMARY: The Food and Drug
Administration (FDA) has determined
the regulatory review period for
CLOLAR and is publishing this notice of
that determination as required by law.
FDA has made the determination
because of the submission of an
application to the Director of Patents
and Trademarks, Department of
Commerce, for the extension of a patent
which claims that human drug product.
ADDRESSES: Submit written comments
and petitions to the Division of Dockets
Management (HFA–305), Food and Drug
Administration, 5630 Fishers Lane, rm.
1061, Rockville, MD 20852. Submit
electronic comments to https://
www.fda.gov/dockets/ecomments.
FOR FURTHER INFORMATION CONTACT:
Beverly Friedman, Office of Regulatory
Policy (HFD–007), Food and Drug
Administration, 5600 Fishers Lane,
Rockville, MD 20857, 301–594–2041.
SUPPLEMENTARY INFORMATION: The Drug
Price Competition and Patent Term
Restoration Act of 1984 (Public Law 98–
417) and the Generic Animal Drug and
Patent Term Restoration Act (Public
Law 100–670) generally provide that a
patent may be extended for a period of
up to 5 years so long as the patented
item (human drug product, animal drug
product, medical device, food additive,
or color additive) was subject to
VerDate Aug<31>2005
17:46 Sep 22, 2006
Jkt 208001
regulatory review by FDA before the
item was marketed. Under these acts, a
product’s regulatory review period
forms the basis for determining the
amount of extension an applicant may
receive.
A regulatory review period consists of
two periods of time: A testing phase and
an approval phase. For human drug
products, the testing phase begins when
the exemption to permit the clinical
investigations of the human drug
product becomes effective and runs
until the approval phase begins. The
approval phase starts with the initial
submission of an application to market
the human drug product and continues
until FDA grants permission to market
the drug product. Although only a
portion of a regulatory review period
may count toward the actual amount of
extension that the Director of Patents
and Trademarks may award (for
example, half the testing phase must be
subtracted as well as any time that may
have occurred before the patent was
issued), FDA’s determination of the
length of a regulatory review period for
a human drug product will include all
of the testing phase and approval phase
as specified in 35 U.S.C. 156(g)(1)(B).
FDA recently approved for marketing
the human drug product CLOLAR
(clofarabine). CLOLAR is indicated for
the treatment of pediatric patients 1 to
21 years old with relapsed or refractory
acute lymphoblastic leukemia after at
least two prior regimens. Subsequent to
this approval, the Patent and Trademark
Office received a patent term restoration
application for CLOLAR (U.S. Patent
No. 5,661,136) from Southern Research
Institute, and the Patent and Trademark
Office requested FDA’s assistance in
determining this patent’s eligibility for
patent term restoration. In a letter dated
February 24, 2006, FDA advised the
Patent and Trademark Office that this
human drug product had undergone a
regulatory review period and that the
approval of CLOLAR represented the
first permitted commercial marketing or
use of the product. Shortly thereafter,
the Patent and Trademark Office
requested that FDA determine the
product’s regulatory review period.
FDA has determined that the
applicable regulatory review period for
CLOLAR is 2,200 days. Of this time,
1,926 days occurred during the testing
phase of the regulatory review period,
while 274 days occurred during the
approval phase. These periods of time
were derived from the following dates:
1. The date an exemption under
section 505(i) of the Federal Food, Drug,
and Cosmetic Act (the act) (21 U.S.C.
355(i)) became effective: December 22,
1998. The applicant claims February 10,
PO 00000
Frm 00026
Fmt 4703
Sfmt 4703
55799
1999, as the date the investigational new
drug application (IND) became effective.
However, FDA records indicate that the
IND effective date was December 22,
1998, the date FDA removed the clinical
hold on the application.
2. The date the application was
initially submitted with respect to the
human drug product under section
505(b) of the act: March 30, 2004. The
applicant claims September 26, 2003, as
the date the new drug application
(NDA) for CLOLAR (NDA 21–673) was
initially submitted. However, FDA
records indicate that NDA 21–673 was
submitted in its entirety on March 30,
2004.
3. The date the application was
approved: December 28, 2004. FDA has
verified the applicant’s claim that NDA
21–673 was approved on December 28,
2004.
This determination of the regulatory
review period establishes the maximum
potential length of a patent extension.
However, the U.S. Patent and
Trademark Office applies several
statutory limitations in its calculations
of the actual period for patent extension.
In its application for patent extension,
this applicant seeks 1,303 days of patent
term extension.
Anyone with knowledge that any of
the dates as published are incorrect may
submit to the Division of Dockets
Management (see ADDRESSES) written or
electronic comments and ask for a
redetermination by November 24, 2006.
Furthermore, any interested person may
petition FDA for a determination
regarding whether the applicant for
extension acted with due diligence
during the regulatory review period by
March 26, 2007. To meet its burden, the
petition must contain sufficient facts to
merit an FDA investigation. (See H.
Rept. 857, part 1, 98th Cong., 2d sess.,
pp. 41–42, 1984.) Petitions should be in
the format specified in 21 CFR 10.30.
Comments and petitions should be
submitted to the Division of Dockets
Management. Three copies of any
mailed information are to be submitted,
except that individuals may submit one
copy. Comments are to be identified
with the docket number found in
brackets in the heading of this
document. Comments and petitions may
be seen in the Division of Dockets
Management between 9 a.m. and 4 p.m.,
Monday through Friday.
Dated: September 1, 2006.
Jane A. Axelrad,
Associate Director for Policy, Center for Drug
Evaluation and Research.
[FR Doc. 06–8115 Filed 9–22–06; 8:45 am]
BILLING CODE 4160–01–S
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Agencies
[Federal Register Volume 71, Number 185 (Monday, September 25, 2006)]
[Notices]
[Pages 55798-55799]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 06-8110]
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
Administration for Children and Families
Proposed Information Collection Activity; Comment Request
Proposed Projects
Title: DHHS/ACF/ASPE/DOL Enhanced Services for the Hard-to-Employ
Demonstration and Evaluation: Rhode Island 15-Month Survey Amendment.
OMB No. 0970-0276.
Description: The Enhanced Services for the Hard-to-Employe
Demonstration and Evaluation Project (HtE) seeks to learn what works in
this area to date and is explicitly designed to build on past research
by rigorously testing a wide variety of approaches to promote
employment and improve family functioning and child well-being. The HtE
project is designed to help Temporary Assistance for Needy Families
(TANF) recipients, former TANF recipients, or low-income parents who
are hard-to-employ. The project is sponsored by the Office of Planning,
Research and Evaluation (OPRE) of the Administration for Children and
Families (ACF), the Office of the Assistant Secretary for Planning and
Evaluation (ASPE) in the U.S. Department of Health and Human Services
(HHS), and the U.S. Department of Labor (DOL).
The evaluation involves an experimental, random assignment design
in four sites, testing a diverse set of strategies to promote
employment for low-income parents who face serious obstacles to
employment. The four include: (1) Intensive care management to
facilitate the use of evidence-based treatment for major depression
among parents receiving Medicaid in Rhode Island; (2) job readiness
training, worksite placements, job coaching, job development and other
training opportunities for recent parolees in New York City; (3) pre-
employment services and transitional employment for long-term TANF
participants in Philadelphia; and (4) home- and center-based care,
enhanced with self-sufficiency services, for low-income families who
have young children or are expecting in Kansas and Missouri.
Materials for follow-up surveys for each of these sites were
previously submitted to OMB and were approved. The purpose of this
submission is to add physiological measures to the follow-up effort to
the Rhode Island study.
Respondents: The respondents to this component of the Rhode Island
follow-up survey will be low-income parents and their children from the
Rhode Island site currently participating in the HtE Project. As
described in the prior OMB submission, these parents are Medicaid
recipients between the ages of 18 and 45 receiving Medicaid through the
managed care provider United Behavioral Health (UBH) in Rhode Island
who meet study criteria with regard to their risk for depression.
Children are the biological, adopted, and step-children of these
parents, between the ages of 1 and 18 years of age.
The annual burden estimates are detailed below, and the substantive
content of each component will be detailed in the supporting statement
attached to the forthcoming 30-day notice.
Annual Burden Estimates
----------------------------------------------------------------------------------------------------------------
Number of
Instrument Number of responses per Average burden hours Total burden
respondents respondent per response hours
----------------------------------------------------------------------------------------------------------------
RI 15-month, parent physiological 400 8 5 minutes or .08 hrs... 266.66
component.
RI 15-month young child physiological 160 8 5 minutes or .08 hrs... 106.66
component.
RI 15-month youth physiological 242 8 5 minutes or .08 hrs... 161.33
component.
----------------------------------------------------------------------------------------------------------------
Estimated Total Annual Burden Hours: 534.65.
In compliance with the requirements of Section 3506(c)(2)(A) of the
Paperwork Reduction Act of 1995, the Administration for Children and
Families is soliciting public comment on the specific aspects of the
information collection described above. Copies of the proposed
collection of information can be obtained and comments may be forwarded
by writing to the Administration for Children and Families, Office of
Administration, Office of Information Services, 370 L'Enfant Promenade,
SW., Washington, DC 20447, Attn: ACF Reports Clearance Officer. E-mail
address: infocollection@acf.hhs.gov. All requests should be identified
by the title of the information collection.
The Department specifically requests comments on: (a) Whether the
proposed collection of information is necessary for the proper
performance of the functions of the agency, including whether the
information shall have
[[Page 55799]]
practical utility; (b) the accuracy of the agency's estimate of the
burden of the proposed collection of information; (c) the quality,
utility, and clarity of the information to be collected; and (d) ways
to minimize the burden of the collection of information on respondents,
including through the use of automated collection techniques or other
forms of information technology. Consideration will be given to
comments and suggestions submitted within 60 days of this publication.
Dated: September 19, 2006.
Robert Sargis,
Reports Clearance Officer.
[FR Doc. 06-8110 Filed 9-22-06; 8:45 am]
BILLING CODE 4184-01-M