Center for Substance Abuse Treatment; Notice of Meeting, 47845 [05-16164]
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Federal Register / Vol. 70, No. 156 / Monday, August 15, 2005 / Notices
alterations in expression of the TGFb
receptors I and II (TbRI and TbRII) are
also observed during pancreatic cancer
progression. These observations are
consistent with an integral role of the
TGFb pathway components in pancreas
biology and disease progression.
However, the molecular details and the
target cell population of TGFb signals
during pancreas development and
disease are not known.
SMAD proteins are downstream
mediators of signals from TGFb 1,2,3
and activin, and SMAD proteins have
been implicated as important factors in
cellular proliferation, differentiation
and migration. This invention identifies
another important regulatory role for the
TGFb-signaling pathway in insulin
production. The inventors have shown
that low levels of TGFb can suppress
insulin production through the actions
of the SMAD signaling proteins. Small
molecule regulators of SMADdependent signaling may lead to better
insulin production and allow better
glucose regulation. Thus, controlled
administration of TGFb signaling
regulators may be useful in the
treatment of diabetes, hyperglycemia
and related complications.
In addition to licensing, the
technology is available for further
development through collaborative
research opportunities with the
inventors.
Anti-Marinobufagenin Antibodies and
Methods for Their Use
Alexei Bagrov et al. (NIA).
U.S. Provisional Application No. 60/
694,733 filed 27 Jun 2005 (HHS
Reference No. E–092–2004/0–US–01).
Licensing Contact: Fatima Sayyid; 301–
435–4521; sayyidf@mail.nih.gov.
Pre-eclampsia is associated with
increased blood levels of
marinobufagenin (MBG), a steroid that
increases blood pressure by inhibiting a
membrane enzyme, Na/K ATPase, in the
vascular wall. Pre-eclampsia
complicates up to 10% of pregnancies
in the U.S. and is a significant factor in
causing maternal and fetal mortality and
morbidity worldwide.
The present invention relates to
compositions and methods for detecting
the presence of MBG in a biological
sample. It also relates to methods for the
use of monoclonal antibodies or antigen
binding fragments as prophylactic,
therapeutic, and diagnostic agents for
the detection, inhibition and treatment
of hypertension.
In addition to licensing, the
technology is available for further
development through collaborative
research opportunities with the
inventors.
VerDate jul<14>2003
13:17 Aug 12, 2005
Jkt 205001
Dated: August 5, 2005.
Steven M. Ferguson,
Director, Division of Technology Development
and Transfer, Office of Technology Transfer,
National Institutes of Health.
[FR Doc. 05–16138 Filed 8–12–05; 8:45 am]
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Substance Abuse and Mental Health
Services Administration
Center for Substance Abuse
Treatment; Notice of Meeting
Pursuant to Public Law 92–463,
notice is hereby given of a
Teleconference Meeting of the Center
for Substance Abuse Treatment (CSAT)
National Advisory Council to be held
August 15, 2005.
The meeting will include the review,
discussion and evaluation of grant
applications reviewed by Initial Review
Groups. Therefore, the meeting will be
closed to the public as determined by
the SAMHSA Administrator, in
accordance with Title 5 U.S.C.
552b(c)(6) and 5 U.S.C. App. 2, 10(d).
Substantive program information and
a roster of Council members may be
obtained by accessing the SAMHSA
Advisory Council Web site (https://
www.samhsa.gov) as soon as possible
after the meeting, or by communicating
with the contact whose name and
telephone number are listed below.
Committee Name: Substance Abuse and
Mental Health Services Administration,
Center for Substance Abuse Treatment
National Advisory Council.
Meeting Date: August 15, 2005.
Place: 1 Choke Cherry Road, 5th Floor
Conference Room, Rockville, MD 20857.
Type: Closed: August 15, 2005–11 a.m.–12
p.m.
Contact: Cynthia Graham, M.S., NAC
Executive Secretary, SAMHSA/CSAT
National Advisory Council, 1 Choke Cherry
Road, Room 5–1036, Rockville, MD 20857.
Telephone: (240) 276–1692. FAX: (240) 276–
1690. E-mail:
cynthia.graham@samhsa.hhs.gov.
This notice is being published less than 15
days prior to the meeting due to the urgent
need to meet timing limitations imposed by
the Department and the review and funding
cycle.
Dated: August 10, 2005.
Toian Vaughn,
Committee Management Officer, Substance
Abuse and Mental Health, Services
Administration.
[FR Doc. 05–16164 Filed 8–12–05; 8:45 am]
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47845
DEPARTMENT OF THE INTERIOR
Fish and Wildlife Service
Information Collection Renewal To Be
Sent to the Office of Management and
Budget (OMB) for Approval Under the
Paperwork Reduction Act; OMB
Control Number 1018–0119; Policy for
Evaluating Conservation Efforts When
Making Listing Decisions
Fish and Wildlife Service,
Interior.
ACTION: Notice; request for comments.
AGENCY:
SUMMARY: We (Fish and Wildlife
Service, Service) plan to send OMB a
request to renew approval for
information collections associated with
our Policy for Evaluation of
Conservation Efforts When Making
Listing Decisions (PECE). We use the
information that we collect as part of the
basis for identifying conservation efforts
that can contribute to a decision to not
list a species under the Endangered
Species Act (ESA) or to list a species as
threatened rather than endangered.
DATES: You must submit comments on
or before October 14, 2005.
ADDRESSES: Send your comments on
this information collection to Hope
Grey, Information Collection Clearance
Officer, Fish and Wildlife Service, MS
222–ARLSQ, 4401 North Fairfax Drive
Arlington, Virginia 22203 (mail);
hope_grey@fws.gov (e-mail); or (703)
358–2269 (fax).
FOR FURTHER INFORMATION CONTACT: To
request a copy of the information
collection requirements or explanatory
material, contact Hope Grey,
Information Collection Clearance
Officer, at the above addresses or by
telephone at (703) 358–2482. For
information related to the Policy for
Evaluation of Conservation Efforts
When Making Listing Decisions, please
visit our Web site at https://
www.fws.gov/endangered/listing/pecefinal.pdf.
The OMB
regulations at 5 CFR 1320, which
implement provisions of the Paperwork
Reduction Act of 1995 (44 U.S.C. 3501
et seq.), require that interested members
of the public and affected agencies have
an opportunity to comment on
information collection and
recordkeeping activities (see 5 CFR
1320.8(d)). We will ask OMB to renew
approval of the collection of information
for certain types of conservation
agreements, conservation plans, and
similar documents in relation to PECE
(68 FR 15100, March 28, 2003). The
current OMB control number for this
SUPPLEMENTARY INFORMATION:
E:\FR\FM\15AUN1.SGM
15AUN1
]]>Agencies
[Federal Register Volume 70, Number 156 (Monday, August 15, 2005)]
[Notices]
[Page 47845]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 05-16164]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
Substance Abuse and Mental Health Services Administration
Center for Substance Abuse Treatment; Notice of Meeting
Pursuant to Public Law 92-463, notice is hereby given of a
Teleconference Meeting of the Center for Substance Abuse Treatment
(CSAT) National Advisory Council to be held August 15, 2005.
The meeting will include the review, discussion and evaluation of
grant applications reviewed by Initial Review Groups. Therefore, the
meeting will be closed to the public as determined by the SAMHSA
Administrator, in accordance with Title 5 U.S.C. 552b(c)(6) and 5
U.S.C. App. 2, 10(d).
Substantive program information and a roster of Council members may
be obtained by accessing the SAMHSA Advisory Council Web site (https://
www.samhsa.gov) as soon as possible after the meeting, or by
communicating with the contact whose name and telephone number are
listed below.
Committee Name: Substance Abuse and Mental Health Services
Administration, Center for Substance Abuse Treatment National
Advisory Council.
Meeting Date: August 15, 2005.
Place: 1 Choke Cherry Road, 5th Floor Conference Room,
Rockville, MD 20857.
Type: Closed: August 15, 2005-11 a.m.-12 p.m.
Contact: Cynthia Graham, M.S., NAC Executive Secretary, SAMHSA/
CSAT National Advisory Council, 1 Choke Cherry Road, Room 5-1036,
Rockville, MD 20857. Telephone: (240) 276-1692. FAX: (240) 276-1690.
E-mail: cynthia.graham@samhsa.hhs.gov.
This notice is being published less than 15 days prior to the
meeting due to the urgent need to meet timing limitations imposed by
the Department and the review and funding cycle.
Dated: August 10, 2005.
Toian Vaughn,
Committee Management Officer, Substance Abuse and Mental Health,
Services Administration.
[FR Doc. 05-16164 Filed 8-12-05; 8:45 am]
BILLING CODE 4162-20-P
