Wisconsin Administrative Code
Department of Natural Resources
NR 100-199 - Environmental Protection General
Chapter NR 149 - Laboratory Accreditation
Subchapter VII - Quality Systems
Section NR 149.40 - Standard operating procedures

Universal Citation: WI Admin Code ยง NR 149.40

Current through August 26, 2024

(1) A laboratory shall maintain written standard operating procedures that document or reference activities needed to maintain its quality systems and that enable performing or reproducing an analysis in its entirety as performed at the laboratory. Each laboratory shall develop, maintain, and keep current its standard operating procedures for both sample preparation and analysis.

Note: Sample preparation includes digestions, distillations, extractions, concentrations, dilutions, and clean-up performed on samples prior to the determinative analytical step.

(2) Standard operating procedures may be documents written by laboratory personnel or may consist entirely of copies of published documents, manuals, or procedures if the laboratory follows the chosen source exactly.

(3) Standard operating procedures may consist, in part, of copies of published documents, manuals, or procedures if all the following conditions are met:

(a) Modifications to the published source are described in writing in additional documents.

(b) Clarifications, changes, or choices are completely described in additional documents, when published sources offer multiple options, ambiguous directives, or insufficient detail to perform or reproduce an analysis.

(4) Standard operating procedures shall indicate the dates of issue or revision.

(5) When the standard operating procedure is written by the laboratory, each standard operating procedure shall include, address, or refer to all the following elements, if applicable:

(a) Identification of the referenced method.

(b) For multi-analyte methods, a list of analytes.

(c) Potential interferences and how the interferences are treated.

(d) Equipment and analytical instruments.

(e) Consumable supplies, reagents, and standards.

(f) Sample preservation, storage, and hold time.

(g) Quality control samples and frequency of the analysis. (h) Calibration and standardization.

(i) Procedure for analysis.

(j) Data assessment and acceptance criteria for quality control measures.

(k) Corrective actions and contingencies for handling out of control or unacceptable data.

Disclaimer: These regulations may not be the most recent version. Wisconsin may have more current or accurate information. We make no warranties or guarantees about the accuracy, completeness, or adequacy of the information contained on this site or the information linked to on the state site. Please check official sources.
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