Mississippi Administrative Code
Title 15 - Mississippi Department of Health
Part 8 - Office of Health Policy and Planning
Subpart 90 - Planning and Resource Development
Chapter 05 - Acute Care Facilities and Services Overview
Section 15-8-90-05-507 - Stereotactic Radiosurgery

Despite its name, stereotactic radiosurgery is a non-surgical procedure that uses highly focused x-rays (or in some cases, gamma rays) to treat certain types of tumors, inoperable lesions, and as a postoperative treatment to eliminate any leftover tumor tissue. Stereotactic radiosurgery treatment involves the delivery of a single high-dose - or in some cases, smaller multiple doses - of radiation beams that converge on the specific area of the brain where the tumor or other abnormality resides.

Stereotactic radiosurgery was once limited to the GammaKnife® for treating intra-cranial lesions and functional issues. With the introduction of CyberKnife® and other LINAC-based radiosurgery systems, there has been rapid growth in total-body radiosurgery. The modified LINAC radiosurgery modality is now being used to treat lung, liver, pancreas, prostate, and other body areas. Some modified full-body LINAC models use full-body frames as a guiding tool and others do not. Therefore, the term "stereotactic radiosurgery" will refer to radiosurgery regardless of whether a full-body frame is used or not. A full course of radiosurgery requires only one to five (5) treatments versus thirty (30) to forty (40) for radiotherapy.

Three (3) basic types of stereotactic radiosurgery are in common use, each of which uses different instruments and sources of radiation:

Cobalt 60 Based (Gamma Knife), which uses 201 beams of highly focused gamma rays. Because of its incredible accuracy, the Gamma Knife is ideal for treating small to medium size lesions.

Linear accelerator (LINAC) based machines, prevalent throughout the world, deliver high-energy x-ray photons or electrons in curving paths around the patient's head. The linear accelerator can perform radiosurgery on larger tumors in a single session or during multiple sessions (fractionated stereotactic radiotherapy). Multiple manufacturers make linear accelerator machines, which have names such as: Axess®, Clinac®, Cyberknife®, Novalis®, Peacock®, TomoTherapy®, Trilogy®, or X-Knife®. According to Accuray, the CyberKnife® is the world's only robotic radiosurgery system designed to treat tumors anywhere in the body non-invasively and with sub-millimeter accuracy.

Particle beam (photon) or cyclotron based machines are in limited use in North America.

Table 5-5 presents the facilities offering megavoltage therapeutic radiation therapy.