Michigan Administrative Code
Department - State Police
Forensic Science Division
Alcohol and Drug Testing of Biological and Nonbiological Specimens
Section R. 325.2673 - Acceptable analytical methods
Current through Vol. 24-04, March 15, 2024
Rule 3. The following are acceptable analytical methods for determining the presence or concentration, or both, of alcohol and other drugs in blood, urine, or other various matrices or media.
(a) Liquid chromatography/mass spectrometry method using a High Performance Liquid Chromatograph/Ultra High Performance Liquid Chromatograph (HPLC/UHPLC) and mass analyzer system including, but not limited to, a quadrupole mass spectrometer, ion trap, time of flight mass spectrometer, magnetic or electromagnetic analyzer, or any hybrid combination thereof, demonstrating satisfactory accuracy, precision, sensitivity, and a suitable column for the identification or quantitation, or both, of drugs or compounds other than ethanol.
(b) Gas chromatograph method using a gas chromatograph that has satisfactory accuracy, precision, sensitivity, and a suitable column for direct injection or head-space gas chromatography for ethyl alcohol and other volatiles.
(c) Gas chromatography/mass spectrometry method using a gas chromatograph and mass spectrometer that have satisfactory accuracy, precision, sensitivity, and a suitable column for direct injection or head-space gas chromatography for identification or quantitation, or both, of drugs or compounds other than ethanol.
(d) Spectrophotometric methods as follows:
(e) Enzymatic and immunological methods as follows:
(f) Analyzers as follows:
(g) Analyzers or kits employing indicator-labeled immunoassays in which an indicator is attached to an antigen or antibody to demonstrate that antigen-antibody binding has occurred, thereby allowing measurement of a drug or other compound in a sample. These include the following: