Current through Register Vol. 50, No. 9, September 20, 2024
A. Electrodiagnostic (EDX) studies are well
established and widely accepted for evaluation of patients suspected of having
CTS. The results are highly sensitive and specific for the diagnosis. Studies
may confirm the diagnosis or direct the examiner to alternative disorders.
Studies require clinical correlation due to the occurrence of false positive
and false negative results. Symptoms of CTS may occur with normal EDX studies,
especially early in the clinical course. EDX findings in CTS reflect slowing of
median motor and sensory conduction across the carpal tunnel region due to
demyelination. Axonal loss, when present, is demonstrated by needle
electromyography in median nerve-supplied thenar muscles. Findings include
fibrillations, fasciculations, neurogenic recruitment and polyphasic units
(reinnervation).
1. Needle electromyography
of a sample of muscles innervated by the C5 to T1 spinal roots, including a
thenar muscle innervated by the median nerve of the symptomatic limb, is
frequently required.
2. The
following EDX studies are not recommended to confirm a clinical diagnosis of
CTS:
a. Low sensitivity and specificity
compared to other EDX studies: multiple median F wave parameters, median motor
nerve residual latency, and sympathetic skin response
b. Investigational studies: evaluation of the
effect on median NCS of limb ischemia, dynamic hand exercises, and brief or
sustained wrist positioning
3. To assure accurate testing, temperature
should be maintained at 30-34C preferably recorded from the hand/digits. For
temperature below 30C the hand should be warmed.
4. All studies must include normative values
for their laboratories.
5. Positive
Findings Any of these nerve conduction study findings must be accompanied by
median nerve symptoms to establish the diagnosis.
a. Slowing of median distal sensory and/or
motor conduction through the carpal tunnel region
b. Electromyographic changes in the median
thenar muscles in the absence of proximal abnormalities
c. Suggested guidelines for the upper limits
of normal latencies:
i. Median distal motor
latency (DML)-4.5msec/8cm
ii.
Median distal sensory peak latency (DSL)-3.6msec/14cm
iii. Median intrapalmar peak latency
(palm-wrist)-2.2msec/8cm
iv.
Median-ulnar palmar sensory latency difference greater than 0.3msec
6. Because laboratories
establish their own norms, a degree of variability from the suggested guideline
values is acceptable.
7. In all
cases, normative values are to be provided with the neurodiagnostic
evaluation.
8. Suggested grading
scheme by electrodiagnostic criteria for writing a consultation or report may
be:
a. Mild CTS-prolonged (relative or
absolute) median sensory or mixed action potential distal latency (orthodromic,
antidromic, or palmar).
b. Moderate
CTS-abnormal median sensory latencies as above, and prolongation (relative or
absolute) of median motor distal latency.
c. Severe CTS-prolonged median motor and
sensory distal latencies, with either absent or sensory or palmar potential, or
low amplitude or absent thenar motor action potential. Needle examination
reveals evidence of acute and chronic denervation with axonal loss.
9. Frequency of Studies/Maximum
Number of Studies:
a. Indications for Initial
Testing
i. patients who do not improve
symptomatically or functionally with conservative measures for carpal tunnel
syndrome over a three to four week period;
ii. patients in whom the diagnosis is in
question;
iii. patients for whom
surgery is contemplated;
iv. to
rule out other nerve entrapments or a radiculopathy.
b. repeated studies may be performed:
i. to determine disease progression. 8-12
weeks is most useful when the initial studies were normal and CTS is still
suspected.
ii. for inadequate
improvement with non-surgical treatment for 8-12 weeks ;
iii. for persistent or recurrent symptoms
following carpal tunnel release, post-op three to six months, unless an earlier
evaluation is required by the surgeon.
B. Imaging Studies
1. Radiographic Imaging . Not generally
required for most CTS diagnoses. However, it may be necessary to rule out other
pathology in the cervical spine, shoulder, elbow, wrist or hand. Wrist and
elbow radiographs would detect degenerative joint disease, particularly
scapholunate dissociation and thumb carpometacarpal abnormalities which
occasionally occur with CTS.
2.
Magnetic Resonance Imaging (MRI). Considered experimental and not recommended
for diagnosis of Carpal Tunnel Syndrome. Trained neuroradiologists have not
identified a single MRI parameter that is highly sensitive and specific. MRI is
less accurate than standard electrodiagnostic testing, and its use as a
diagnostic tool is not recommended.
3. Sonography . This tool has not been
sufficiently studied to define its diagnostic performance relative to
electrodiagnostic studies. It is not a widely applied test. Sonography may
detect synovial thickening in CTS caused by rheumatoid arthritis. It may be
useful if space-occupying lesions, such as, lipomas, hemangiomas, fibromas, and
ganglion cysts, are suspected. Its routine use in CTS is not
recommended.
C.
Adjunctive testing . Clinical indications for the use of tests and measurements
are predicated on the history and systems review findings, signs observed on
physical examination, and information derived from other sources and
records.They are not designed to be the definitive indicator of dysfunction.
1. Electromyography . is a generally
accepted, well-established procedure. It is indicated when acute and/or chronic
neurogenic changes in the thenar eminence are associated with the conduction
abnormalities discussed above.
2.
Electroneurometer is not recommended as a diagnostic tool because it requires
patient participation, cannot distinguish between proximal and distal lesions,
and does not have well-validated reference values.
3. Portable Automated Electrodiagnostic.
Device measures distal median nerve motor latency and F-wave latency at the
wrist and has been tested in one research setting. It performed well in this
setting following extensive calibration of the device. Motor nerve latency
compared favorably with conventional electrodiagnostic testing, but F-wave
latency added little to diagnostic accuracy. It remains an investigational
instrument whose performance in a primary care setting is as yet not
established, and is not recommended as a substitute for conventional
electrodiagnostic testing in clinical decision-making.
4. Quantitative Sensory Testing (QST) may be
used as a screening tool in clinical settings pre- and post-operatively.
Results of tests and measurements of sensory integrity are integrated with the
history and systems review findings and the results of other tests and
measures. QST has been divided into two types of testing:
a. Threshold tests measure topognosis, the
ability to exactly localize a cutaneous sensation, and pallesthesia, the
ability to sense mechanical using vibration discrimination testing (quickly
adapting fibers); Semmes-Wienstein monofilament testing (slowly adapting
fibers);
b. Density Tests also
measure topognosis and pallesthesia using static two-point discrimination
(slowly adapting fibers); moving two-point discrimination (quickly adapting
fibers).
5. Pinch and
Grip Strength Measurements are Not generally accepted as a diagnostic tool for
CTS. Strength is defined as the muscle force exerted by a muscle or group of
muscles to overcome a resistance under a specific set of circumstances. Pain,
the perception of pain secondary to abnormal sensory feedback, and/or the
presence of abnormal sensory feedback affecting the sensation of the power used
in grip/pinch may cause a decrease in the force exerted and thereby not be a
true indicator of strength. When all five handle settings of the dynamometer
are used, a bell-shaped curve, reflecting maximum strength at the most
comfortable handle setting, should be present. These measures provide a method
for quantifying strength that can be used to follow a patient's progress and to
assess response to therapy. In the absence of a bell-shaped curve, clinical
reassessment is indicated.
6.
Laboratory Tests . In one study of carpal tunnel patients seen by specialists,
nine percent of patients were diagnosed with diabetes, seven percent with
hypothyroidism, and 15 percent with chronic inflammatory disease including
spondyloarthropathy, arthritis, and systemic lupus erythematosis. Up to two
thirds of the patients were not aware of their concurrent disease. Estimates of
the prevalence of hypothyroidism in the general population vary widely, but
data collected from the Colorado Thyroid Disease Prevalence Study revealed
subclinical hypothyroidism in 8.5 percent of participants not taking thyroid
medication. The prevalence of chronic joint symptoms in the Behavioral Risk
Factor Surveillance System (BRFSS) from the Centers for Disease Control (CDC)
was 12.3 percent. If after two to three weeks, the patient is not improving the
physician should strongly consider the following laboratory studies: thyroid
function studies, rheumatoid screens, chemical panels, and others, if
clinically indicated. Laboratory testing may be required periodically to
monitor patients on chronic medications.
D. Special tests are generally well-accepted
tests and are performed as part of a skilled assessment of the patients'
capacity to return to work, his/her strength capacities, and physical work
demand classifications and tolerance.
1.
Personality/Psychological/Psychiatric/ Psychosocial Evaluations .
a. These are generally accepted and
well-established diagnostic procedures with selective use in the upper
extremity population, but have more widespread use in subacute and chronic
upper extremity populations. Diagnostic testing procedures may be useful for
patients with symptoms of depression, delayed recovery, chronic pain, recurrent
painful conditions, disability problems, and for preoperative evaluation.
Psychological/psychosocial and measures have been shown to have predictive
value for postoperative response, and therefore should be strongly considered
for use pre-operatively when the surgeon has concerns about the relationship
between symptoms and findings, or when the surgeon is aware of indications of
psychological complication or risk factors for psychological complication (e.g.
childhood psychological trauma). Psychological testing should provide
differentiation between pre-existing conditions versus injury caused
psychological conditions, including depression and posttraumatic stress
disorder. Psychological testing should incorporate measures that have been
shown, empirically, to identify comorbidities or risk factors that are linked
to poor outcome or delayed recovery;
b. Formal psychological or psychosocial
evaluation should be performed on patients not making expected progress within
6 to 12 weeks following injury and whose subjective symptoms do not correlate
with objective signs and test results. In addition to the customary initial
exam, the evaluation of the injured worker should specifically address the
following areas:
i. employment
history;
ii. interpersonal
relationships-both social and work;
iii. patient activities;
iv. current perception of the medical
system;
v. current
perception/attitudes toward employer/job;
vi. results of current treatment;
vii. risk factors and psychological
comorbidities that may influence outcome and that may require
treatment;
viii. childhood history,
including history of childhood psychological trauma, abuse and family history
of disability.
c.
Personality/psychological/psychosocial evaluations consist of two components,
clinical interview and psychological testing. Results should help clinicians
with a better understanding of the patient in a number of ways. Thus the
evaluation result will determine the need for further psychosocial
interventions; and in those cases, Diagnostic and Statistical Manual of Mental
Disorders (DSM) diagnosis should be determined and documented. The evaluation
should also include examination of both psychological comorbidities and
psychological risk factors that are empirically associated with poor outcome
and/or delayed recovery. An individual with a Ph.D., Psy.D, or psychiatric
M.D./D.O. credentials should perform initial evaluations, which are generally
completed within one to two hours. A professional fluent in the primary
language of he patient is preferred. When such a provider is not available,
services of a professional language interpreter should be provided.
d. Frequency: one-time visit for the clinical
interview. If psychometric testing is indicated as a part of the initial
evaluation, time for such testing shall be allotted at least, six hours of
professional time or whatever is deemed appropriate by the health care
professional.
i. Job site evaluation is a
comprehensive analysis of the physical, mental and sensory components of a
specific job. These components may include, but are not limited to: postural
tolerance (static and dynamic); aerobic requirements; range of motion;
torque/force; lifting/carrying; cognitive demands; social interactions; visual
perceptual; environmental requirements of a job; repetitiveness; and essential
functions of a job. Job descriptions provided by the employer are helpful but
should not be used as a substitute for direct observation.
(a). Frequency: One time with additional
visits as needed for follow-up per job site.
ii. Functional Capacity evaluation is a
comprehensive or modified evaluation of the various aspects of function as they
relate to the worker's ability to return to work. Areas such as endurance,
lifting (dynamic and static), postural tolerance, specific range of motion,
coordination and strength, worker habits, employability and financial status,
as well as psychosocial aspects of competitive employment may be evaluated.
Components of this evaluation may include: musculoskeletal screen;
cardiovascular profile/aerobic capacity; coordination; lift/carrying analysis;
job-specific activity tolerance; maximum voluntary effort; pain
assessment/psychological screening; and non-material and material handling
activities.
(a). Frequency: Can be used
initially to determine baseline status. Additional evaluations can be performed
to monitor and assess progress and aid in determining the endpoint for
treatment.
iii.
Vocational Assessment : The vocational assessment should provide valuable
guidance in the determination of future rehabilitation program goals. It should
clarify rehabilitation goals, which optimize both patient motivation and
utilization of rehabilitation resources. If prognosis for return to former
occupation is determined to be poor, except in the most extenuating
circumstances, vocational assessment should be implemented within 3 to 12
months post-injury. Declaration of MMI should not be delayed solely due to lack
of attainment of a vocational assessment.
(a).
Frequency: One time with additional visits as needed for follow-up
iv. Work Tolerance Screening: is a
determination of an individual's tolerance for performing a specific job as
based on a job activity or task. It may include a test or procedure to
specifically identify and quantify work-relevant cardiovascular, physical
fitness and postural tolerance. It may also address ergonomic issues affecting
the patient's return-to-work potential. May be used when a full FCE is not
indicated.
(a) . Frequency: One time for
evaluation. May monitor improvements in strength every three to four weeks up
to a total of six evaluations.
AUTHORITY
NOTE: Promulgated in accordance with
R.S.
23:1203.1.