Kentucky Administrative Regulations
Title 810 - PUBLIC PROTECTION CABINET - KENTUCKY HORSE RACING COMMISSION
Chapter 8 - Medication Guidelines
Section 810 KAR 8:025E - Drug, medication, and substance withdrawal guidelines
Current through Register Vol. 50, No. 9, March 1, 2024
RELATES TO: KRS 230.215, 230.225, 230.240, 230.260, 230.265, 230.290, 230.320, 230.370
NECESSITY, FUNCTION, AND CONFORMITY: KRS 230.215(2) authorizes the Kentucky Horse Racing Commission to promulgate administrative regulations prescribing conditions under which all legitimate horse racing and wagering thereon is conducted in Kentucky. KRS 230.240(2) requires the commission to promulgate administrative regulations restricting or prohibiting the administration of drugs or stimulants or other improper acts to horses prior to the horse participating in a race. This administrative regulation establishes the withdrawal guidelines for permitted drugs, medications, and substances that may be administered to race horses competing in Kentucky.
Section 1. The Kentucky Horse Racing Commission Withdrawal Guidelines Thoroughbred; Standardbred; Quarter Horse, Appaloosa, and Arabian.
Substance |
Brand Name |
Recommended Minimum Withdrawal |
Administration Specifications |
Aceproma-zine |
Prom-Ace |
48 hours |
0.05 mg/kg via IV administration |
Acetylcyste-ine |
Muco-myst |
24 hours |
Inhalation |
Albuterol |
Proventil |
72 hours |
720 mcg via inhalation |
Beclome-thasone |
Beclo-vent |
24 hours |
Inhalation only |
Butorphanol |
Tor-bugesic |
48 hours |
0.1 mg/kg via IV administration |
Cetirizine |
Zyrtec |
48 hours |
0.4 mg/ml orally twice daily for 5 doses |
Cimetadine |
Tagamet |
24 hours |
20 mg/kg orally twice daily for 7 doses |
Clenbuterol |
Ventip-ulmin |
21 days |
0.8 mcg/kg orally Pursuant to 810 KAR 8:010 Section 10, clenbuterol shall be prohibited unless the prescription is made for a specific horse based on a specific diagnosis. The veterinarian shall provide a copy of the treatment sheet to the Equine Medical Director or de-signee for review within twenty-four (24) hours of administration. A horse administered clenbuterol shall be placed on the veterinarian's list for at least twenty-one (21) days after the last administration. The horse shall meet all conditions for removal from the list, including negative blood and urine sampling. |
Cromolyn sodium |
Intal |
24 hours |
Inhalation |
Dantrolene |
Dantri-um |
48 hours |
500 mg orally |
Detomidine |
Dor-mosedan |
48 hours |
5 mg via IV administration |
Dexame-thasone |
Azium |
72 hours IV PO, with no other cortico-steroids administered. 5 days if other corticosteroids have been administered. |
IV, PO, IM, pursuant to the European Horserace Scientific Liaison Committee. |
DMSO |
48 hours |
Topical, IV, or oral administration up to 60 ml |
|
Ergonovine |
48 hours |
No dose specified |
|
Fenoterol |
48 hours |
Via inhalation, no dose specified |
|
Furosemide 2-year-olds beginning in 2020 Stakes horses beginning in 2021 |
Salix |
24 hours |
Administration shall be prohibited at less than 24 hours, and limited to a maximum 500 mg single dose via IV administration |
Furosemide |
Salix |
4 hours |
150-500 mg single IV dose administered by KHRC veterinarian. See 810 KAR 8:010 Section 6. |
Guaifenesin |
48 hours |
2 g orally twice daily for 5 doses |
|
Glyco-pyrrolate |
Robinol |
48 hours |
1 mg |
Griseofulvin |
Fulvacin |
24 hours |
No dose specified |
Hyaluronic Acid |
Legend |
24 hours |
IV administration only; no dose specified |
Hydroxyzine |
Atarax |
96 hours |
No dose specified |
Ipratropium |
48 hours |
Via inhalation, no dose specified |
|
Isoxsuprine |
Vasodi-lan |
48 hours |
No dose specified |
Ketocona-zole |
Nizoral |
24 hours |
No dose specified |
Lidocaine |
72 hours |
200 mg total dose SQ |
|
Mepivacaine |
Carbo-caine |
72 hours |
0.07 mg/kg SQ |
Methocar-bamol |
Robaxin |
48 hours |
15 mg/kg single IV |
Methyler-gonovine |
Mether-gine |
48 hours |
No dose specified |
Misoprostol |
Cytotec |
24 hours |
No dose specified |
Omeprazole |
Gas-trogard |
24 hours |
2.2 g orally once daily for 4 days |
Omeprazole |
Gas-trogard |
24 hours |
2.2 g orally once daily for 4 days |
Pentoxyfyl-line |
Trental |
48 hours |
No dose specified |
Phenytoin |
Dilantin |
96 hours |
No dose specified |
Ponazur-il/Diclazuril/S ulfadiazine-Pyrimetham-ine |
Mar-quis/Prot azil |
24 hours |
Oral |
Procaine Penicillin |
48 hours |
17 mg/kg IM Procaine penicillin treatments shall be reported to the stewards no later than twenty-four (24) hours after the last injection is administered. Horses so treated may be required to be under commission-approved, continuous surveillance for the six-hour interval prior to the post time for the race in which the horse is entered. The owner of the horse shall be responsible for all costs associated with the surveillance. Prospective surveillance arrangements shall be submitted to the stewards no later than close of business on the day of entry. |
|
PSGAG |
Ad-equan |
24 hours |
Via IM administration |
Ranitidine |
Zantac |
24 hours |
8 mg/kg orally twice daily for 7 doses |
Reserpine |
Serpasil |
7 days |
No dose specified |
Romifidine |
Sedivet |
72 hours |
50 mg via IV administration |
Salmeterol |
48 hours |
Via inhalation, no dose specified |
|
Sucralfate |
Carafate |
24 hours |
No dose specified |
Terbutaline |
48 hours |
No dose specified |
|
Xylazine |
Rompun |
48 hours |
200 mg via IV administration |
Substance |
Brand Name |
Recommended Minimum Withdrawal |
Administration Specifications |
Phenylbut-azone |
Butazol-idin |
48 hours-single elected NSAID. If this is not the single elected NSAID, then 7 days, pursuant to the European Horserace Scientific Liaison Committee. |
4.4 mg/kg via IV administration |
Flunixin |
Bana-mine |
48 hours-single elected NSAID. If this is not the single elected NSAID, then 6 days, pursuant to the European Horserace Scientific Liaison Committee. |
1.1 mg/kg via IV administration |
Ketoprofen |
Ketofen |
48 hours-single elected NSAID, If this is not the single elected NSAID, then 4 days, pursuant to the European Horserace Scientific Liaison Committee. |
2.2 mg/kg via IV administration |
Diclofenac |
Surpass |
7 days, pursuant to the European Horserace Scientific Liaison Committee. |
5 inch ribbon of Surpass every 12 hours to one site |
Firocoxib |
Equioxx |
15 days, pursuant to the European Horserace Scientific Liaison Committee. |
0.1 mg/kg once daily for 4 days |
Substance |
Brand Name |
Recommended Minimum Withdrawal |
Administration Specifications |
Anthemintics (except thi-azide products |
72 hours |
||
Non-androgenic reproductive hormones |
Including HCG, Regu-mate, GnRH, in fillies and mares only |
24 hours |
|
Proprionibacterium acnes suspension or comparable immunostimulants |
24 hours |
||
Electrolytes, vitamins, minerals |
24 hours |
Via IV or IM administration |
|
Antibiotics |
24 hours |
||
Any injectable other than furosemide |
24 hours |
810 KAR 8:010 specifically prohibits any injections at less than 24 hours to post time for any substance. |
|
Intra-articular injections, other than corticosteroids |
72 hours |
Section 2.
Substance |
Threshold |
Acepromazine |
10 nanograms per ml in urine of hydroxyethylpromazine sulfox-ide (HEPS) |
Albuterol |
1 nanogram per ml in urine |
Boldenone Male horses other than geldings |
15 nanograms per ml in urine of boldenone, free and conjugated OR 25 picograms per ml in serum or plasma of boldenone, free |
Boldenone Geldings and female Horses |
1 nanogram per mil in urine of boldenone, free and conjugated |
Butorphanol |
2 nanograms per ml in serum or plasma of butorphanol, free OR 300 nanograms per ml in urine of total butorphanol |
Cetirizine |
6 nanograms per ml in serum or plasma |
Cimetadine |
400 nanograms per ml in serum or plasma |
Clenbuterol |
Limit of detection in both urine and blood |
Dantrolene |
0.1 nanograms per ml of serum or plasma of 5-OH dantrolene |
Detomidine |
2 nanogram per ml in urine of carboxydetomidine OR 1 nanogram per ml of detomidine in serum or plasma |
Diclofenac |
5 nanograms per ml in serum or plasma |
DMSO |
10 micrograms per ml in serum or plasma |
Firocoxib |
20 nanograms per ml in serum or plasma |
Flunixin |
5 nanograms per ml in serum or plasma |
Furosemide |
For horses eligible to race on furosemide, 100 nanograms per ml in serum or plasma AND Urine specific gravity of less than 1.010 OR 1 nanogram per ml in serum or plasma for 2-year-olds beginning in 2020 or stakes horses beginning in 2021, see 810 KAR 8:010 |
Glycopyrrolate |
3 picograms per ml in serum or plasma |
Guaifenesin |
12 nanograms per ml in serum or plasma |
Ketoprofen |
2 nanograms per ml of serum or plasma |
Lidocaine |
20 picograms per ml in serum or plasma of Total 3-OH-lidocaine |
Mepivacaine |
10 nanograms per ml in urine of OH-mepivicaine OR Limit of detection in serum or plasma |
Methocarbamol |
1 nanogram per ml in serum or plasma |
Methylprednisolone |
100 picograms per ml in serum or plasma |
Nandrolone Male horses other than geldings |
45 nanograms per ml in urine of 5a-estrane-3ß, 17a-diol OR In urine a ratio of 5a estrane-3ß, 17 a-diol to 5a estrene-3ß, 17 a-diol of > 1:1 |
Nandrolone Geldings and female horses |
1 nanogram per ml in urine of nandrolone, free and conjugated OR 50 picograms per ml of procaine in blood, serum, or plasma of nandrolone, free |
Omeprazole |
10 nanograms per ml omeprazole sulfide in serum or plasma |
Phenylbutazone |
0.3 micrograms per ml in serum or plasma |
Prednisolone |
10 nanograms per ml free Prednisolone in urine |
Procaine Penicillin Horses reported to have been treated with procaine penicillin |
25 nanograms per ml of procaine in serum or plasma Procaine penicillin treatments shall be reported to the stewards no later than 24 hours after the last injection is administered. Horses so treated may be required to be under KHRC approved, continuous surveillance for the six hour interval prior to the post time for the race in which the horse is entered. The owner of the horse shall be responsible for all costs associated with the surveillance. Prospective surveillance arrangements shall be submitted to the stewards no later than close of business on the day of entry. |
Procaine Penicillin Horses not reported to have been treated with procaine penicillin |
Limit of detection for procaine in serum or plasma Procaine penicillin treatments shall be reported to the stewards no later than 24 hours after the last injection is administered. Horses so treated may be required to be under KHRC approved, continuous surveillance for the six hour interval prior to the post time for the race in which the horse is entered. The owner of the horse shall be responsible for all costs associated with the surveillance. Prospective surveillance arrangements shall be submitted to the stewards no later than close of business on the day of entry. |
Ranitidine |
40 nanograms per ml in serum or plasma |
Testosterone Geldings |
20 nanograms per ml in urine of testosterone, free and conjugated OR 25 picograms per ml in serum or plasma of testosterone, free |
Testosterone Female horses (unless in foal) |
55 nanograms per ml in urine of testosterone, free and conjugated OR 100 picograms per ml in serum or plasma of testosterone, free |
Xylazine |
200 picograms per ml in serum or plasma |
STATUTORY AUTHORITY: KRS 230.215(2), 230.225, 230.240(2), 230.260, 230.320, 230.370