Current through Register Vol. 48, No. 38, September 20, 2024
a) Non-Steroidal Anti-Inflammatories (NSAID):
Threshold Levels
1) Only one non-steroidal
anti-inflammatory drug (NSAID) may be present in a horse's body while it is
participating in a race. The presence of more than one NSAID greater than the
threshold level is forbidden and will result in the purse being
redistributed.
2) Subject to the
prohibition contained in Section
603.40 (24
hour ban), the only foreign substances that now meet the criteria established
in Section 603.60 are cimetidine, furosemide, omeprazole sulfide, and
ranitidine.
3) Laboratory reports
of phenylbutazone in a concentration greater than or equal to 0.3 mcg/ml in
serum or plasma, flunixin in a concentration greater than or equal to 5 ng/ml
in serum or plasma, and ketoprofen in a concentration greater than or equal to
2 ng/ml in serum or plasma shall be treated as Class 4 drugs, category "C"
penalty, as defined in the Association of Racing Commissioners International
Uniform Classification Guidelines for Foreign Substances (ARCI, 1510 Newtown
Pike, Suite 210, Lexington KY 40511; January 2020 version
14.1; this incorporation
includes no later amendments or editions).
4) A finding by the Board's laboratory of any
amount of oxyphenbutazone in the absence of phenylbutazone shall be treated as
a Class 4 drug, as defined in the ARCI Guidelines for Foreign Substances
(incorporated by reference in subsection (a)(3)).
5) The detection of one or more additional
NSAIDs in blood and/or urine constitutes a stacking violation in addition to
the violation associated with the detection of each additional NSAID.
6) If the phenylbutazone, flunixin or
ketoprofen overage is due to the negligence of the veterinarian attending the
horse, the veterinarian shall be subject to the same penalties as are set forth
in the ARCI Guidelines for Foreign Substances (incorporated by reference in
subsection (a)(3)).
7) Penalties
for violations of this Section shall be based on the following criteria:
A) previous warnings and rulings for
violations of this Section;
B) the
age and experience of the violator;
C) whether the violator has ever been the
subject of a medication ruling in this or any other racing
jurisdiction;
D) what action, if
any, was taken to avoid the violation;
E) the purse of the race.
b) The following
foreign substances may be administered externally to a horse entered to a race:
Leg paints and liniment that do not contain any "caine" derivatives,
pharmacodynamic and/or chemotherapeutic agents, and that can be applied
topically without penetrating the skin.
c) Subject to the prohibition contained in
Section
603.40
(24-hour ban), the following foreign substances, commonly referred to as
anti-bacterial, anti-fungal, or anti-protozoal drugs, may be present in the
body of a horse participating in a race.
1)
Anti-Bacterials
Amikacin
Ampicillin
Ampicillin sodium
Azolsulfamide
Chloramphenicol
Doxycycline
Enrofloxacin (Baytril)
Erythromycin sulfate
Gentamicin sulfate
Kanamycin sulfate
Methenamine
Metronidazole
Neomycin sulfate
Nitrofurantoin
Oxytetracycline
Penicillin G. Benzathine
Penicillin G. Potassium
Sulfadimethozine
Sulfadimethoxine
Sulfamethoxazole
Sulfametranidazole
Sulfapyridine
Sulfathiazole
Tetracycline
Trimethoprim
2) Anti-Fungals
Amphotericin B
Griseofulvin
Neomycin Undecyclenate
Nystatin
3)
Anti-Protozoals
Nitazoxanide (Navigator)
Ponazuril (Marquis)
Pyrimethamine (Daraprim)
d) This listing of anti-bacterial,
anti-fungal and anti-protozoal drugs is all inclusive and shall not include any
other anti-bacterial, anti-fungal or anti-protozoal drug, except as provided in
subsection (f).
e) A foreign
substance of accepted therapeutic value may be administered as prescribed by a
veterinarian when threshold levels and guidelines for its use have been
approved by the Board and this Part has been duly amended. The Board shall give
due consideration to threshold levels and guidelines, when making additions to
the permitted list, that have been established by the ARCI Guidelines for
Foreign Substances (incorporated by reference in subsection (a)(3)).
f) Subject to the prohibition contained in
Section
603.40 (24
hour ban), the use of the following therapeutic medications shall be permitted.
The official test samples may contain the following therapeutic medications in
concentrations less than the following threshold levels:
1) Acepromazine - 10 ng/ml as
2-(1-hydroxyethyl) promazine sulfoxide (HEPS) in urine.
2) Albuterol - 1 ng/ml in urine.
3) Betamethasone (harness racing only) - 10
pg/ml in serum or plasma.
4)
Butorphanol - 300 ng/ml of total butorphanol in urine.
5) Cetirizine - 6 ng/ml in serum or
plasma.
6) Cimetidine - 400 ng/ml
in serum or plasma.
7) Clenbuterol
- 140 pg/ml in urine in thoroughbred and quarter horse breeds; and Limit of
Detection (which is not less than 10 pg/ml) in serum or plasma in the
standardbred breed.
8) Dantrolene -
100 pg/ml of 5-hydroxydantrolene in serum or plasma.
9) Detomidine - Level of Detection for
detomidine in serum or plasma.
10)
Dexamethasone (harness racing only) - 5 pg/ml in serum or plasma.
11) Diclofenac - Level of Detection if
found.
12) Dimethyl sulfoxide
(DMSO) - 10 mcg/ml in serum or plasma.
13) Firocoxib - Level of Detection if
found.
14) Furosemide - 100 ng/ml
in serum or plasma.
15)
Glycopyrrlate - 3 pg/ml in serum or plasma.
16) Guaifenesin - 12 ng/ml in serum or
plasma.
17) Isoflupredone (harness
racing only) - 100 pg/ml in serum or plasma.
18) Lidocaine - 20 pg/ml of total
3-hydroxylidocaine in serum or plasma.
19) Mepivacaine - 10 ng total
hydroxymepivacaine/ml in urine.
20)
Methocarbamol - 1 ng/ml in serum or plasma.
21) Methylprednisolone - 100 pg/ml in serum
or plasma.
22) Omeprazole sulfide -
10 ng/ml in serum or plasma.
23)
Prednisolone (harness racing only) - 1 ng/ml in serum or plasma.
24) Procaine penicillin - 25 ng/ml of
procaine in serum or plasma. Procaine penicillin must be reported to the Board
at time of administration and shall not be administered after the horse is
entered to race.
25) Ranitidine -
40 ng/ml in serum or plasma.
26)
Triamcinolone acetonide (harness racing only) - 100 pg/ml in serum or
plasma.
27) Xylazine - 200 pg/ml in
serum or plasma.
g)
Laboratory reports of the therapeutic medications listed in subsection (f)
greater than or equal to their respective threshold level shall be treated as
they are defined and classified in the Association of Racing Commissioners
International Uniform Classification Guidelines for Foreign Substances
(incorporated by reference in subsection (a)(3)).
h) Official test samples may contain any of
the following drug substances, or their metabolites, in a concentration less
than the threshold level:
1) Isoxsuprine -
shall be less than 1,000 ng/ml in urine.
2) Pyrilamine - shall be less than 50 ng/ml
of O-desmethyl pyrilamine in urine.
i) The provisions of this Section shall be
applied retroactively when substantively applicable, including all actions
pending before the Board without regard to when the cause of action accrued;
provided, however, that this subsection shall not operate to affect rights of
individuals that have fully vested.
j) To help licensees determine the test
levels of substances contained in this Section, the Board laboratory will test,
at the sole expense of the licensee for the actual cost of processing the
sample, all equine urine, serum or plasma samples submitted to it that are
accompanied by a certification indicating time, method and route of
administration.
