California Code of Regulations
Title 27 - Environmental Protection
Division 4 - Office of Environmental Health Hazard Assessment
Chapter 1 - Safe Drinking Water and Toxic Enforcement Act of 1986
Article 9 - Miscellaneous
Section 27001 - Chemicals Known to the State to Cause Cancer or Reproductive Toxicity

Universal Citation: 27 CA Code of Regs 27001

Current through Register 2024 Notice Reg. No. 38, September 20, 2024

(a) The Safe Drinking Water and Toxic Enforcement Act of 1986 requires that the Governor revise and republish at least once per year the list of chemicals known to the State to cause cancer or reproductive toxicity. The identification number indicated in the following list is the Chemical Abstracts Service (CAS) Registry Number. No CAS number is given when several substances are presented as a single listing. The date refers to the initial appearance of the chemical on the list.

(b) Chemicals known to the state to cause cancer.

Chemical CAS Number Date
A-alpha-C (2-Amino-9H-pyrido[2,3-b]indole) 26148-68-5 January 1, 1990
Acetaldehyde 75-07-0 April 1, 1988
Acetamide 60-35-5 January 1, 1990
Acetochlor 34256-82-1 January 1, 1989
2-Acetylaminofluorene 53-96-3 July 1, 1987
Acifluorfen sodium 62476-59-9 January 1, 1990
Acrylamide 79-06-1 January 1, 1990
Acrylonitrile 107-13-1 July 1, 1987
Actinomycin D 50-76-0 October 1, 1989
AF-2;[2-(2-furyl)-3-(5-nitro-2-furyl)]acrylamide 3688-53-7 July 1, 1987
Aflatoxins -- January 1, 1988
Alachlor 15972-60-8 January 1, 1989
Alcoholic beverages -- April 29, 2011
Alcoholic beverages, when associated with alcohol abuse -- July 1, 1988
Aldrin 309-00-2 July 1, 1988
Aloe vera, non-decolorized whole leaf extract December 4, 2015
2-Aminoanthraquinone 117-79-3 October 1, 1989
p-Aminoazobenzene 60-09-3 January 1, 1990
o-Aminoazotoluene 97-56-3 July 1, 1987
4-Aminobiphenyl (4-amino-diphenyl) 92-67-1 February 27, 1987
2-Amino-4-chlorophenol 95-85-2 September 13, 2019
1-Amino-2,4-dibromoanthraquinone 81-49-2 August 26, 1997
3-Amino-9-ethylcarbazole hydrochloride 6109-97-3 July 1, 1989
2-Aminofluorene 153-78-6 January 29, 1999
1-Amino-2-methylanthraquinone 82-28-0 October 1, 1989
2-Amino-5-(5-nitro-2-furyl)-1,3,4-thiadiazole 712-68-5 July 1, 1987
4-Amino-2-nitrophenol 119-34-6 January 29, 1999
Amitrole 61-82-5 July 1, 1987
Amsacrine 51264-14-3 August 7, 2009
Analgesic mixtures containing phenacetin -- February 27, 1987
Androstenedione 63-05-8 May 3, 2011
Aniline 62-53-3 January 1, 1990
Aniline hydrochloride 142-04-1 May 15, 1998
o-Anisidine 90-04-0 July 1, 1987
o-Anisidine hydrochloride 134-29-2 July 1, 1987
Anthracene 120-12-7 August 11, 2023
Anthraquinone 84-65-1 September 28, 2007
Antimony oxide (Antimony trioxide) 1309-64-4 October 1, 1990
Aramite 140-57-8 July 1, 1987
Areca nut -- February 3, 2006
Aristolochic acids -- July 9, 2004
Arsenic (inorganic arsenic compounds) -- February 27, 1987
Asbestos 1332-21-4 February 27, 1987
Auramine 492-80-8 July 1, 1987
Azacitidine 320-67-2 January 1, 1992
Azaserine 115-02-6 July 1, 1987
Azathioprine 446-86-6 February 27, 1987
Azobenzene 103-33-3 January 1, 1990
Benthiavalicarb-isopropyl 177406-68-7 July 1, 2008
Benz[a]anthracene 56-55-3 July 1, 1987
Benzene 71-43-2 February 27, 1987
Benzidine [and its salts] 92-87-5 February 27, 1987
Benzidine-based dyes -- October 1, 1992
Benzo[b]fluoranthene 205-99-2 July 1, 1987
Benzo[j]fluoranthene 205-82-3 July 1, 1987
Benzo[k]fluoranthene 207-08-9 July 1, 1987
Benzofuran 271-89-6 October 1, 1990
Benzophenone 119-61-9 June 22, 2012
Benzo[a]pyrene 50-32-8 July 1, 1987
Benzotrichloride 98-07-7 July 1, 1987
Benzyl chloride 100-44-7 January 1, 1990
Benzyl violet 4B 1694-09-3 July 1, 1987
Beryllium and beryllium compounds -- October 1, 1987
Betel quid with tobacco -- January 1, 1990
Betel quid without tobacco -- February 3, 2006
2,2-Bis(bromomethyl)-1,3-propanediol 3296-90-0 May 1, 1996
Bis(2-chloroethyl)ether 111-44-4 April 1, 1988
N,N-Bis(2-chloroethyl)-2-naphthylamine (Chlornapazine) 494-03-1 February 27, 1987
Bischloroethyl nitrosourea (BCNU) (Carmustine) 154-93-8 July 1, 1987
Bis(chloromethyl)ether 542-88-1 February 27, 1987
Bis(2-chloro-l-methylethyl)ether, technical grade -- October 29, 1999
Bitumens, extracts of steam-refined and air refined -- January 1, 1990
Bracken fern -- January 1, 1990
Bromate 15541-45-4 May 31, 2002
Bromochloroacetic acid 5589-96-8 April 6, 2010
1-Bromo-3-chloropropane 109-70-6 January 27, 2023
Bromodichloroacetic acid 71133-14-7 July 29, 2016
Bromodichloromethane 75-27-4 January 1, 1990
Bromoethane 74-96-4 December 22, 2000
Bromoform 75-25-2 April 1, 1991
1-Bromopropane (1-BP) 106-94-5 August 5, 2016
2-Bromopropane 45-26-3 August 11, 2023
1,3-Butadiene 106-99-0 April 1, 1988
1,4-Butanediol dimethanesulfonate (Busulfan) 55-98-1 February 27, 1987
Butylated hydroxyanisole 25013-16-5 January 1, 1990
1-Butyl glycidyl ether 2426-08-6 January 27, 2023
beta-Butyrolactone 3068-88-0 July 1, 1987
Cacodylic acid 75-60-5 May 1, 1996
Cadmium and cadmium compounds -- October 1, 1987
Caffeic acid 331-39-5 October 1, 1994
Captafol 2425-06-1 October 1, 1988
Captan 133-06-2 January 1, 1990
Carbaryl 63-25-2 February 5, 2010
Carbazole 86-74-8 May 1, 1996
Carbon black (airborne, unbound particles of respirable size) 1333-86-4 February 21, 2003
Carbon-black extracts -- January 1, 1990
Carbon tetrachloride 56-23-5 October 1, 1987
N-Carboxymethyl-N-nitrosourea 60391-92-6 January 25, 2002
Catechol 120-80-9 July 15, 2003
Ceramic fibers (airborne particles of respirable size) -- July 1, 1990
Certain combined chemotherapy for lymphomas -- February 27, 1987
Chloral 75-87-6 September 13, 2013
Chloral hydrate 302-17-0 September 13, 2013
Chlorambucil 305-03-3 February 27, 1987
Chloramphenicol sodium succinate 982-57-0 September 27, 2013
Chlordane 57-74-9 July 1, 1988
Chlordecone (Kepone) 143-50-0 January 1, 1988
Chlordimeform 6164-98-3 January 1, 1989
Chlorendic acid 115-28-6 July 1, 1989
Chlorinated paraffins (Average chain length, C12; approximately 60 percent chlorine by weight) 108171-26-2 July 1, 1989
p-Chloroaniline 106-47-8 October 1, 1994
p-Chloroaniline hydrochloride 20265-96-7 May 15, 1998
Chloroethane (Ethyl chloride) 75-00-3 July 1, 1990
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) (Lomustine) 13010-47-4 January 1, 1988
1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea (Methyl-CCNU) 13909-09-6 October 1, 1988
Chloroform 67-66-3 October 1, 1987
Chloromethyl methyl ether (technical grade) 107-30-2 February 27, 1987
3-Chloro-2-methylpropene 563-47-3 July 1, 1989
1-Chloro-4-nitrobenzene 100-00-5 October 29, 1999
2-Chloronitrobenzene 88-73-3 September 13, 2019
4-Chloro-o-phenylenediamine 95-83-0 January 1, 1988
Chloroprene 126-99-8 June 2, 2000
Chlorothalonil 1897-45-6 January 1, 1989
p-Chloro-o-toluidine 95-69-2 January 1, 1990
p-Chloro-o-toluidine, strong acid salts of -- May 15, 1998
5-Chloro-o-toluidine and its strong acid salts -- October 24, 1997
Chlorotrianisene 569-57-3 September 1, 1996
p-chloro-?,?,?-trifluorotoluene (para-Chlorobenzotrifluoride, PCBTF) June 28, 2019
Chlorozotocin 54749-90-5 January 1, 1992
Chromium (hexavalent compounds) -- February 27, 1987
Chrysene 218-01-9 January 1, 1990
C. I. Acid Red 114 6459-94-5 July 1, 1992
C.I. Basic Red 9 monohydrochloride 569-61-9 July 1, 1989
C.I. Direct Blue 15 2429-74-5 August 26, 1997
C.I. Direct Blue 218 28407-37-6 August 26, 1997
C.I. Disperse Yellow 3 2832-40-8 February 8, 2013
C.I. Solvent Yellow 14 842-07-9 May 15, 1998
Ciclosporin (Cyclosporin A; Cyclosporine) 59865-13-3 January 1, 1992
79217-60-0
Cidofovir 113852-37-2 January 29, 1999
Cinnamyl anthranilate 87-29-6 July 1, 1989
Cisplatin 15663-27-1 October 1, 1988
Citrus Red No. 2 6358-53-8 October 1, 1989
Clofibrate 637-07-0 September 1, 1996
Clomiphene citrate 50-41-9 May 24, 2013
CMNP (pyrazachlor) 6814-58-0 August 25, 2015
Coal-tar pitch -- November 17, 2023
Cobalt metal powder 7440-48-4 July 1, 1992
Cobalt [II] oxide 1307-96-6 July 1, 1992
Cobalt sulfate 10124-43-3 May 20, 2005
Cobalt sulfate heptahydrate 10026-24-1 June 2, 2000
Coconut oil diethanolamine condensate (cocamide diethanolamine) -- June 22, 2012
Coke oven emissions -- February 27, 1987
Conjugated estrogens -- February 27, 1987
Creosotes -- October 1, 1988
p-Cresidine 120-71-8 January 1, 1988
Cumene 98-82-8 April 6, 2010
Cupferron 135-20-6 January 1, 1988
Cycasin 14901-08-7 January 1, 1988
Cyclopenta[cd]pyrene 27208-37-3 April 29, 2011
Cyclophosphamide (anhydrous) 50-18-0 February 27, 1987
Cyclophosphamide (hydrated) 6055-19-2 February 27, 1987
Cytembena 21739-91-3 May 15, 1998
D&C Orange No. 17 3468-63-1 July 1, 1990
D&C Red No. 8 2092-56-0 October 1, 1990
D&C Red No. 9 5160-02-1 July 1, 1990
D&C Red No. 19 81-88-9 July 1, 1990
Dacarbazine 4342-03-4 January 1, 1988
Daminozide 1596-84-5 January 1, 1990
Dantron (Chrysazin; 1,8-Dihydroxyanthraquinone) 117-10-2 January 1, 1992
Daunomycin 20830-81-3 January 1, 1988
DDD (Dichlorodiphenyldichloroethane) 72-54-8 January 1, 1989
DDE (Dichlorodiphenyldichloroethylene) 72-55-9 January 1, 1989
DDT (Dichlorodiphenyltrichloroethane) 50-29-3 October 1, 1987
DDVP (Dichlorvos) 62-73-7 January 1, 1989
N,N'-Diacetylbenzidine 613-35-4 October 1, 1989
2,4-Diaminoanisole 615-05-4 October 1, 1990
2,4-Diaminoanisole sulfate 39156-41-7 January 1, 1988
4,4'-Diaminodiphenyl ether (4,4'-Oxydianiline) 101-80-4 January 1, 1988
2,4-Diaminotoluene 95-80-7 January 1, 1988
Diazoaminobenzene 136-35-6 May 20, 2005
Dibenz[a,h]acridine 226-36-8 January 1, 1988
Dibenz[a,j]acridine 224-42-0 January 1, 1988
Dibenzanthracenes -- December 26, 2014
Dibenz[a,c]anthracene 215-58-7 December 26, 2014
Dibenz[a,h]anthracene 53-70-3 January 1, 1988
Dibenz[a,j]anthracene 224-41-9 December 26, 2014
7H-Dibenzo[c,g]carbazole 194-59-2 January 1, 1988
Dibenzo[a,e]pyrene 192-65-4 January 1, 1988
Dibenzo[a,h]pyrene 189-64-0 January 1, 1988
Dibenzo[a,i]pyrene 189-55-9 January 1, 1988
Dibenzo[a,l]pyrene 191-30-0 January 1, 1988
Dibromoacetic acid 631-64-1 June 17, 2008
Dibromoacetonitrile 3252-43-5 May 3, 2011
1,2-Dibromo-3-chloropropane (DBCP) 96-12-8 July 1, 1987
2,3-Dibromo-1-propanol 96-13-9 October 1, 1994
Dichloroacetic acid 79-43-6 May 1, 1996
p-Dichlorobenzene 106-46-7 January 1, 1989
3,3'-Dichlorobenzidine 91-94-1 October 1, 1987
3,3'-Dichlorobenzidine dihydrochloride 612-83-9 May 15, 1998
1,4-Dichloro-2-butene 764-41-0 January 1, 1990
3,3'-Dichloro-4,4'-diaminodiphenyl ether 28434-86-8 January 1, 1988
1,1-Dichloroethane 75-34-3 January 1, 1990
Dichloromethane (Methylene chloride) 75-09-2 April 1, 1988
1,4-Dichloro-2-nitrobenzene 89-61-2 September 13, 2019
2,4-Dichloro-1-nitrobenzene 661-06-3 September 13, 2019
1,2-Dichloropropane 78-87-5 January 1, 1990
1,3-Dichloro-2-propanol (1,3-DCP) 96-23-1 October 8, 2010
1,3-Dichloropropene 542-75-6 January 1, 1989
Diclofop-methyl 51338-27-3 April 6, 2010
Dieldrin 60-57-1 July 1, 1988
Diepoxybutane 1464-53-5 January 1, 1988
Diesel engine exhaust -- October 1, 1990
Diethanolamine 111-42-2 June 22, 2012
Di(2-ethylhexyl)phthalate (DEHP) 117-81-7 January 1, 1988
1,2-Diethylhydrazine 1615-80-1 January 1, 1988
Diethylstilbestrol (DES) 56-53-1 February 27, 1987
Diethyl sulfate 64-67-5 January 1, 1988
Diglycidyl resorcinol ether (DGRE) 101-90-6 July 1, 1989
Dihydrosafrole 94-58-6 January 1, 1988
Diisononyl phthalate (DINP) -- December 20, 2013
Diisopropyl sulfate 2973-10-6 April 1, 1993
3,3'-Dimethoxybenzidine (o-Dianisidine) 119-90-4 January 1, 1988
3,3'-Dimethoxybenzidine dihydrochloride (o-Dianisidine dihydrochloride) 20325-40-0 October 1, 1990
3,3'-Dimethoxybenzidine-based dyes metabolized to 3,3'-dimethoxybenzidine -- June 11, 2004
N,N-Dimethylacetamide 127-19-5 September 13, 2019
4-Dimethylaminoazobenzene 60-11-7 January 1, 1988
trans-2-[(Dimethylamino)methylimino]-5-[2-(5-nitro-2-furyl)vinyl]-1,3,4-oxadiazole 55738-54-0 January 1, 1988
7,12-Dimethylbenz(a)anthracene 57-97-6 January 1, 1990
3,3'-Dimethylbenzidene (ortho-Tolidine) 119-93-7 January 1, 1988
3,3'-Dimethylbenzidine-based dyes metabolized to 3,3'-dimethylbenzidine -- June 11, 2004
3,3'-Dimethylbenzidine dihydrochloride 612-82-8 April 1, 1992
Dimethylcarbamoyl chloride 79-44-7 January 1, 1988
N,N-Dimethylformamide 68-12-2 October 27, 2017
1,1-Dimethylhydrazine (UDMH) 57-14-7 October 1, 1989
1,2-Dimethylhydrazine 540-73-8 January 1, 1988
Dimethyl Hydrogen Phosphite 868-85-9 August 11, 2023
2,6-Dimethyl-N-nitrosomorpholine (DMNM) 1456-28-6 February 8, 2013
Dimethyl sulfate 77-78-1 January 1, 1988
N,N-Dimethyl-p-toluidine 99-97-8 May 2, 2014
Dimethylvinylchloride 513-37-1 July 1, 1989
3,7-Dinitrofluoranthene 105735-71-5 August 26, 1997
3,9-Dinitrofluoranthene 22506-53-2 August 26, 1997
1,3-Dinitropyrene 75321-20-9 November 2, 2012
1,6-Dinitropyrene 42397-64-8 October 1, 1990
1,8-Dinitropyrene 42397-65-9 October 1, 1990
Dinitrotoluene mixture, 2,4-/2,6- -- May 1, 1996
2,4-Dinitrotoluene 121-14-2 July 1, 1988
2,6-Dinitrotoluene 606-20-2 July 1, 1995
Di-n-propyl isocinchomeronate (MGK Repellent 326) 136-45-8 May 1, 1996
1,4-Dioxane 123-91-1 January 1, 1988
Diphenylhydantoin (Phenytoin) 57-41-0 January 1, 1988
Diphenylhydantoin (Phenytoin), sodium salt 630-93-3 January 1, 1988
Direct Black 38 (technical grade) 1937-37-7 January 1, 1988
Direct Blue 6 (technical grade) 2602-46-2 January 1, 1988
Direct Brown 95 (technical grade) 16071-86-6 October 1, 1988
Disperse Blue 1 2475-45-8 October 1, 1990
Diuron 330-54-1 May 31, 2002
Doxorubicin hydrochloride (Adriamycin) 25316-40-9 July 1, 1987
Emissions from combustion of coal -- August 7, 2013
Emissions from high-temperature unrefined rapeseed oil -- January 3, 2014
Epichlorohydrin 106-89-8 October 1, 1987
Epoxiconazole 135319-73-2 April 15, 2011
Erionite 12510-42-8/ October 1, 1988
66733-21-9
Estradiol 17B 50-28-2 January 1, 1988
Estragole 140-67-0 October 29, 1999
Estrogens, steroidal -- August 19, 2005
Estrogen-progestogen (combined) used as menopausal therapy -- November 4, 2011
Estrone 53-16-7 January 1, 1988
Estropipate 7280-37-7 August 26, 1997
Ethinylestradiol 57-63-6 January 1, 1988
Ethoprop 13194-48-4 February 27, 2001
Ethyl acrylate 140-88-5 July 1, 1989
Ethylbenzene 100-41-4 June 11, 2004
Ethyl-4,4'-dichlorobenzilate 510-15-6 January 1, 1990
Ethylene dibromide 106-93-4 July 1, 1987
Ethylene dichloride (1,2-Dichloroethane) 107-06-2 October 1, 1987
Ethyleneimine (Aziridine) 151-56-4 January 1, 1988
Ethylene oxide 75-21-8 July 1, 1987
Ethylene thiourea 96-45-7 January 1, 1988
2-Ethylhexyl acrylate 103-11-7 December 17, 2021
Ethyl methanesulfonate 62-50-0 January 1, 1988
Etoposide 33419-42-0 November 4, 2011
Etoposide in combination with cisplatin and bleomycin -- November 4, 2011
Fenoxycarb 72490-01-8 June 2, 2000
Fluoro-edenite fibrous amphibole -- November 17, 2023
Folpet 133-07-3 January 1, 1989
Formaldehyde (gas) 50-00-0 January 1, 1988
2-(2-Formylhydrazino)-4-(5-nitro-2-furyl)thiazole 3570-75-0 January 1, 1988
Fumonisin B1 116355-83-0 November 14, 2003
Furan 110-00-9 October 1, 1993
Furazolidone 67-45-8 January 1, 1990
Furfuryl alcohol 98-00-0 September 30, 2016
Furmecyclox 60568-05-0 January 1, 1990
Fusarin C 79748-81-5 July 1, 1995
Gallium arsenide 1303-00-0 August 1, 2008
Ganciclovir 82410-32-0 August 26, 1997
Gasoline engine exhaust (condensates/extracts) -- October 1, 1990
Gemfibrozil 25812-30-0 December 22, 2000
Gentian violet (Crystal violet) 548-62-9 November 23, 2018
Glass wool fibers (inhalable and biopersistent) -- July 1, 1990
Glu-P-1 (2-Amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole) 67730-11-4 January 1, 1990
Glu-P-2 (2-Aminodipyrido[1,2-a:3', 2'-d]imidazole) 67730-10-3 January 1, 1990
Glycidaldehyde 765-34-4 January 1, 1988
Glycidol 556-52-5 July 1, 1990
Glycidyl methacrylate 106-91-2 January 27, 2023
Glyphosate 1071-83-6 July 7, 2017
Goldenseal root powder December 4, 2015
Griseofulvin 126-07-8 January 1, 1990
Gyromitrin (Acetaldehyde methylformylhydrazone) 16568-02-8 January 1, 1988
HC Blue 1 2784-94-3 July 1, 1989
Heptachlor 76-44-8 July 1, 1988
Heptachlor epoxide 1024-57-3 July 1, 1988
Herbal remedies containing plant species of the genus Aristolochia -- July 9, 2004
Hexachlorobenzene 118-74-1 October 1, 1987
Hexachlorobutadiene 87-68-3 May 3, 2011
Hexachlorocyclohexane (technical grade) -- October 1, 1987
Hexachlorodibenzodioxin 34465-46-8 April 1, 1988
Hexachloroethane 67-72-1 July 1, 1990
2,4-Hexadienal (89% trans, trans isomer; 11% cis, trans isomer) -- March 4, 2005
Hexamethylphosphoramide 680-31-9 January 1, 1988
Hydrazine 302-01-2 January 1, 1988
Hydrazine sulfate 10034-93-2 January 1, 1988
Hydrazobenzene (1,2-Diphenylhydrazine) 122-66-7 January 1, 1988
1-Hydroxyanthraquinone 129-43-1 May 27, 2005
Imazalil 35554-44-0 May 20, 2011
Indeno [1,2,3-cd]pyrene 193-39-5 January 1, 1988
Indium phosphide 22398-80-7 February 27, 2001
Indium tin oxide 50926-11-9 March 19, 2021
IQ (2-Amino-3-methylimidazo[4,5-f] quinoline) 76180-96-6 April 1, 1990
Iprodione 36734-19-7 May 1, 1996
Iprovalicarb 140923-17-7 June 1, 2007
140923-25-7
Iron dextran complex 9004-66-4 January 1, 1988
Isobutyl nitrite 542-56-3 May 1, 1996
Isoprene 78-79-5 May 1, 1996
Isopyrazam 881685-58-1 July 24, 2012
Isoxaflutole 141112-29-0 December 22, 2000
Kresoxim-methyl 143390-89-0 February 3, 2012
Lactofen 77501-63-4 January 1, 1989
Lasiocarpine 303-34-4 April 1, 1988
Lead acetate 301-04-2 January 1, 1988
Lead and lead compounds -- October 1, 1992
Lead phosphate 7446-27-7 April 1, 1988
Lead subacetate 1335-32-6 October 1, 1989
Leather dust -- April 29, 2011
Leucomalachite green 129-73-7 April 21, 2023
Lindane and other hexachlorocyclohexane isomers -- October 1, 1989
Lynestrenol 52-76-6 February 27, 2001
Malathion 121-75-5 May 20, 2016
Malonaldehyde, sodium salt 24382-04-5 May 3, 2011
Mancozeb 8018-01-7 January 1, 1990
Maneb 12427-38-2 January 1, 1990
Marijuana smoke -- June 19, 2009
Me-A-alpha-C (2-Amino-3-methyl-9H-pyrido[2,3-b]indole) 68006-83-7 January 1, 1990
Medroxyprogesterone acetate 71-58-9 January 1, 1990
Megestrol acetate 595-33-5 March 28, 2014
MeIQ (2-Amino-3,4-dimethylimidazo[4,5-f]quinoline) 77094-11-2 October 1, 1994
MeIQx (2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline) 77500-04-0 October 1, 1994
Melphalan 148-82-3 February 27, 1987
Mepanipyrim 110235-47-7 July 1, 2008
2-Mercaptobenzothiazole 149-30-4 October 27, 2017
Merphalan 531-76-0 April 1, 1988
Mestranol 72-33-3 April 1, 1988
Metam potassium 137-41-7 December 31, 2010
Metham sodium 137-42-8 November 6, 1998
5-Methoxypsoralen with ultraviolet A therapy 484-20-8 October 1, 1988
8-Methoxypsoralen with ultraviolet A therapy 298-81-7 February 27, 1987
Methyl acrylate 96-33-3 December 17, 2021
2-Methylaziridine (Propyleneimine) 75-55-8 January 1, 1988
Methylazoxymethanol 590-96-5 April 1, 1988
Methylazoxymethanol acetate 592-62-1 April 1, 1988
Methyl carbamate 598-55-0 May 15, 1998
3-Methylcholanthrene 56-49-5 January 1, 1990
5-Methylchrysene 3697-24-3 April 1, 1988
4,4'-Methylene bis(2-chloroaniline) 101-14-4 July 1, 1987
4,4'-Methylene bis(N,N-dimethyl)benzenamine 101-61-1 October 1, 1989
4,4'-Methylene bis(2-methylaniline) 838-88-0 April 1, 1988
4,4'-Methylenedianiline 101-77-9 January 1, 1988
4,4'-Methylenedianiline dihydrochloride 13552-44-8 January 1, 1988
Methyleugenol 93-15-2 November 16, 2001
Methylhydrazine and its salts -- July 1, 1992
2-Methylimidazole 693-98-1 June 22, 2012
4-Methylimidazole 822-36-6 January 7, 2011
Methyl iodide 74-88-4 April 1, 1988
Methyl isobutyl ketone 108-10-1 November 4, 2011
Methylmercury compounds -- May 1, 1996
Methyl methanesulfonate 66-27-3 April 1, 1988
2-Methyl-1-nitroanthraquinone (of uncertain purity) 129-15-7 April 1, 1988
N-Methyl-N'-nitro-N-nitrosoguanidine 70-25-7 April 1, 1988
N-Methylolacrylamide 924-42-5 July 1, 1990
[ALPHA]-Methyl styrene (alpha-Methylstyrene) 98-83-9 November 2, 2012
Methylthiouracil 56-04-2 October 1, 1989
Metiram 9006-42-2 January 1, 1990
Metronidazole 443-48-1 January 1, 1988
Michler's ketone 90-94-8 January 1, 1988
Mirex 2385-85-5 January 1, 1988
Mitomycin C 50-07-7 April 1, 1988
Mitoxantrone hydrochloride 70476-82-3 January 23, 2015
Molybdenum trioxide 1313-27-5 March 19, 2021
MON 4660 (dichloroacetyl-1-oxa-4-azaspiro(4,5)-decane) 71526-07-3 March 22, 2011
MON 13900 (furilazole) 121776-33-8 March 22, 2011
3-Monochloropropane-1,2-diol (3-MCPD) 96-24-2 October 8, 2010
Monocrotaline 315-22-0 April 1, 1988
MOPP (vincristine-prednisone-nitrogen mustard-procarbazine mixture) 113803-47-7 November 4, 2011
5-(Morpholinomethyl)-3-[(5-nitrofurfuryl-idene)-amino]-2-oxazolidinone 139-91-3 April 1, 1988
Mustard Gas 505-60-2 February 27, 1987
MX (3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone) 77439-76-0 December 22, 2000
beta-Myrcene 123-35-3 March 27, 2015
Nafenopin 3771-19-5 April 1, 1988
Nalidixic acid 389-08-2 May 15, 1998
Naphthalene 91-20-3 April 19, 2002
1-Naphthylamine 134-32-7 October 1, 1989
2-Naphthylamine 91-59-8 February 27, 1987
Nickel (Metallic) 7440-02-0 October 1, 1989
Nickel acetate 373-02-4 October 1, 1989
Nickel carbonate 3333-67-3 October 1, 1989
Nickel carbonyl 13463-39-3 October 1, 1987
Nickel compounds -- May 7, 2004
Nickel hydroxide 12054-48-7; October 1, 1989
12125-56-3
Nickelocene 1271-28-9 October 1, 1989
Nickel oxide 1313-99-1 October 1, 1989
Nickel refinery dust from the pyrometallurgical process -- October 1, 1987
Nickel subsulfide 12035-72-2 October 1, 1987
Niridazole 61-57-4 April 1, 1988
Nitrapyrin 1929-82-4 October 5, 2005
Nitrilotriacetic acid 139-13-9 January 1, 1988
Nitrilotriacetic acid, trisodium salt monohydrate 18662-53-8 April 1, 1989
5-Nitroacenaphthene 602-87-9 April 1, 1988
o-Nitroanisole 91-23-6 October 1, 1992
para-Nitroanisole 100-17-4 September 13, 2019
Nitrobenzene 98-95-3 August 26, 1997
4-Nitrobiphenyl 92-93-3 April 1, 1988
6-Nitrochrysene 7496-02-8 October 1, 1990
Nitrofen (technical grade) 1836-75-5 January 1, 1988
2-Nitrofluorene 607-57-8 October 1, 1990
Nitrofurazone 59-87-0 January 1, 1990
1-[(5-Nitrofurfurylidene)-amino]-2-imidazolidinone 555-84-0 April 1, 1988
N-[4-(5-Nitro-2-furyl)-2-thiazolyl]acetamide 531-82-8 April 1, 1988
Nitrogen mustard (Mechlorethamine) 51-75-2 January 1, 1988
Nitrogen mustard hydrochloride (Mechlorethamine hydrochloride) 55-86-7 April 1, 1988
Nitrogen mustard N-oxide 126-85-2 April 1, 1988
Nitrogen mustard N-oxide hydrochloride 302-70-5 April 1, 1988
Nitromethane 75-52-5 May 1, 1997
2-Nitropropane 79-46-9 January 1, 1988
1-Nitropyrene 5522-43-0 October 1, 1990
4-Nitropyrene 57835-92-4 October 1, 1990
N-Nitrosodi-n-butylamine 924-16-3 October 1, 1987
N-Nitrosodiethanolamine 1116-54-7 January 1, 1988
N-Nitrosodiethylamine 55-18-5 October 1, 1987
N-Nitrosodimethylamine 62-75-9 October 1, 1987
p-Nitrosodiphenylamine 156-10-5 January 1, 1988
N-Nitrosodiphenylamine 86-30-6 April 1, 1988
N-Nitrosodi-n-propylamine 621-64-7 January 1, 1988
N-Nitroso-N-ethylurea 759-73-9 October 1, 1987
N-Nitrosohexamethyleneimine 932-83-2 November 23, 2018
3-(N-Nitrosomethylamino)propionitrile 60153-49-3 April 1, 1990
4-(N-Nitrosomethylamino)-1-(3-pyridyl)1-butanone 64091-91-4 April 1, 1990
N-Nitrosomethyl-n-butylamine 7068-83-9 December 26, 2014
N-Nitrosomethyl-n-decylamine 75881-22-0 December 26, 2014
N-Nitrosomethyl-n-dodecylamine 55090-44-3 December 26, 2014
N-Nitrosomethylethylamine 10595-95-6 October 1, 1989
N-Nitrosomethyl-n-heptylamine 16338-99-1 December 26, 2014
N-Nitrosomethyl-n-hexylamine 28538-70-7 December 26, 2014
N-Nitrosomethyl-n-nonylamine 75881-19-5 December 26, 2014
N-Nitrosomethyl-n-octylamine 34423-54-6 December 26, 2014
N-Nitrosomethyl-n-pentylamine 13256-07-0 December 26, 2014
N-Nitrosomethyl-n-propylamine 924-46-9 December 26, 2014
N-Nitrosomethyl-n-tetradecylamine 75881-20-8 December 26, 2014
N-Nitrosomethyl-n-undecylamine 68107-26-6 December 26, 2014
N-Nitroso-N-methylurea 684-93-5 October 1, 1987
N-Nitroso-N-methylurethane 615-53-2 April 1, 1988
N-Nitrosomethylvinylamine 4549-40-0 January 1, 1988
N-Nitrosomorpholine 59-89-2 January 1, 1988
N-Nitrosonornicotine 16543-55-8 January 1, 1988
N-Nitrosopiperidine 100-75-4 January 1, 1988
N-Nitrosopyrrolidine 930-55-2 October 1, 1987
N-Nitrososarcosine 13256-22-9 January 1, 1988
o-Nitrotoluene 88-72-2 May 15, 1998
Norethisterone (Norethindrone) 68-22-4 October 1, 1989
Norethynodrel 68-23-5 February 27, 2001
Ochratoxin A 303-47-9 July 1, 1990
Oil Orange SS 2646-17-5 April 1, 1988
Oral contraceptives, combined -- October 1, 1989
Oral contraceptives, sequential -- October 1, 1989
Oryzalin 19044-88-3 September 12, 2008
Oxadiazon 19666-30-9 July 1, 1991
Oxazepam 604-75-1 October 1, 1994
Oxymetholone 434-07-1 January 1, 1988
Oxythioquinox (Chinomethionat) 2439-01-2 August 20, 1999
Palygorskite fibers (>5?m in length) 12174-11-7 December 28, 1999
Panfuran S 794-93-4 January 1, 1988
Parathion 56-38-2 May 20, 2016
Pentabromodiphenyl ether mixture [DE-71 (technical grade)] -- July 7, 2017
Pentachlorophenol 87-86-5 January 1, 1990
Pentachlorophenol and by-products of its synthesis (complex mixture) -- October 21, 2016
Pentosan polysulfate sodium -- April 18, 2014
Perfluorooctane sulfonic acid (PFOS) and its salts and transformation and degradation precursors -- December 24, 2021
Perfluorooctanoic Acid (PFOA) 335-67-1 February 25, 2022
Phenacetin 62-44-2 October 1, 1989
Phenazopyridine 94-78-0 January 1, 1988
Phenazopyridine hydrochloride 136-40-3 January 1, 1988
Phenesterin 3546-10-9 July 1, 1989
Phenobarbital 50-06-6 January 1, 1990
Phenolphthalein 77-09-8 May 15, 1998
Phenoxybenzamine 59-96-1 April 1, 1988
Phenoxybenzamine hydrochloride 63-92-3 April 1, 1988
o-Phenylenediamine and its salts 95-54-5 May 15, 1998
Phenyl glycidyl ether 122-60-1 October 1, 1990
Phenylhydrazine and its salts -- July 1, 1992
o-Phenylphenate, sodium 132-27-4 January 1, 1990
o-Phenylphenol 90-43-7 August 4, 2000
PhiP(2-Amino-1-methyl-6-phenylimidazol[4,5-b]pyridine) 105650-23-5 October 1, 1994
Pioglitazone 111025-46-8 April 18, 2014
Pirimicarb 23103-98-2 July 1, 2008
Polybrominated biphenyls -- January 1, 1988
Polychlorinated biphenyls -- October 1, 1989
Polychlorinated biphenyls (containing 60 or more percent chlorine by molecular weight) -- January 1, 1988
Polychlorinated dibenzo-p-dioxins -- October 1, 1992
Polychlorinated dibenzofurans -- October 1, 1992
Polygeenan 53973-98-1 January 1, 1988
Ponceau MX 3761-53-3 April 1, 1988
Ponceau 3R 3564-09-8 April 1, 1988
Potassium bromate 7758-01-2 January 1, 1990
Primidone 125-33-7 August 20, 1999
Procarbazine 671-16-9 January 1, 1988
Procarbazine hydrochloride 366-70-1 January 1, 1988
Procymidone 32809-16-8 October 1, 1994
Progesterone 57-83-0 January 1, 1988
Pronamide 23950-58-5 May 1, 1996
Propachlor 1918-16-7 February 27, 2001
1,3-Propane sultone 1120-71-4 January 1, 1988
Propargite 2312-35-8 October 1, 1994
beta-Propiolactone 57-57-8 January 1, 1988
Propoxur 114-26-1 August 11, 2006
Propylene glycol mono-t-butyl ether 57018-52-7 June 11, 2004
Propylene oxide 75-56-9 October 1, 1988
Propylthiouracil 51-52-5 January 1, 1988
Pulegone 89-82-7 April 18, 2014
Pymetrozine 123312-89-0 March 22, 2011
Pyridine 110-86-1 May 17, 2002
Quinoline and its strong acid salts -- October 24, 1997
Radionuclides -- July 1, 1989
Reserpine 50-55-5 October 1, 1989
Residual (heavy) fuel oils -- October 1, 1990
Resmethrin 10453-86-8 July 1, 2008
Riddelliine 23246-96-0 December 3, 2004
Safrole 94-59-7 January 1, 1988
Salted fish, Chinese-style -- April 29, 2011
Sedaxane 874967-67-6 July 1, 2016
Selenium sulfide 7446-34-6 October 1, 1989
Shale-oils 68308-34-9 April 1, 1990
Silica, crystalline (airborne particles of respirable size) -- October 1, 1988
Silicon carbide whiskers -- November 17, 2023
Soots, tars, and mineral oils (untreated and mildly treated oils and used engine oils) -- February 27, 1987
Spirodiclofen 148477-71-8 October 8, 2010
Spironolactone 52-01-7 May 1, 1997
Stanozolol 10418-03-8 May 1, 1997
Sterigmatocystin 10048-13-2 April 1, 1988
Streptozotocin (streptozocin) 18883-66-4 January 1, 1988
Strong inorganic acid mists containing sulfuric acid -- March 14, 2003
Styrene 100-42-5 April 22, 2016
Styrene oxide 96-09-3 October 1, 1988
Sulfallate 95-06-7 January 1, 1988
Sulfasalazine (Salicylazosulfapyridine) 599-79-1 May 15, 1998
Talc containing asbestiform fibers -- April 1, 1990
Tamoxifen and its salts 10540-29-1 September 1, 1996
Teriparatide 52232-67-4 August 14, 2015
Terrazole 2593-15-9 October 1, 1994
Testosterone and its esters 58-22-0 April 1, 1988
Tetrabromobisphenol A 79-94-7 October 27, 2017
3,3',4,4'-Tetrachloroazobenzene 14047-09-7 July 24, 2012
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) 1746-01-6 January 1, 1988
1,1,1,2-Tetrachloroethane 630-20-6 September 13, 2013
1,1,2,2-Tetrachloroethane 79-34-5 July 1, 1990
Tetrachloroethylene (Perchloroethylene) 127-18-4 April 1, 1988
p-?,?,?-Tetrachlorotoluene 5216-25-1 January 1, 1990
Tetrachlorvinphos 22248-79-9 May 20, 2016
Tetrafluoroethylene 116-14-3 May 1, 1997
Tetrahydrofuran 109-99-9 December 17, 2021
Tetranitromethane 509-14-8 July 1, 1990
Thioacetamide 62-55-5 January 1, 1988
4,4'-Thiodianiline 139-65-1 April 1, 1988
Thiodicarb 59669-26-0 August 20, 1999
Thiouracil 141-90-2 June 11, 2004
Thiourea 62-56-6 January 1, 1988
Thorium dioxide 1314-20-1 February 27, 1987
Titanium dioxide (airborne, unbound particles of respirable size) -- September 2, 2011
Tobacco, oral use of smokeless products -- April 1, 1988
Tobacco smoke -- April 1, 1988
Toluene diisocyanate 26471-62-5 October 1, 1989
o-Toluidine 95-53-4 January 1, 1988
o-Toluidine hydrochloride 636-21-5 January 1, 1988
Toxaphene (Polychorinated camphenes) 8001-35-2 January 1, 1988
Toxins derived from Fusarium moniliforme (Fusarium verticillioides) -- August 7, 2009
Treosulfan 299-75-2 February 27, 1987
Triamterene 396-01-0 April 18, 2014
S,S,S-Tributyl phosphorotrithioate (Tribufos, DEF) 78-48-8 February 25, 2011
Trichlormethine (Trimustine hydrochloride) 817-09-4 January 1, 1992
Trichloroacetic acid 76-03-9 September 13, 2013
1,1,1-Trichloroethane 71-55-6 April 21, 2023
Trichloroethylene 79-01-6 April 1, 1988
2,4,6-Trichlorophenol 88-06-2 January 1, 1988
1,2,3-Trichloropropane 96-18-4 October 1, 1992
2,4,5-Trimethylaniline and its strong acid salts -- October 24, 1997
Trimethylolpropane triacrylate, technical grade -- December 17, 2021
Trimethyl phosphate 512-56-1 May 1, 1996
TRIM® VX -- May 25, 2018
2,4,6-Trinitrotoluene (TNT) 118-96-7 December 19, 2008
Triphenyltin hydroxide 76-87-9 July 1, 1992
Tris(1-aziridinyl)phosphine sulfide (Thiotepa) 52-24-4 January 1, 1988
Tris(2-chloroethyl)phosphate 115-96-8 April 1, 1992
Tris(2,3-dibromopropyl)phosphate 126-72-7 January 1, 1988
Tris(1,3-dichloro-2-propyl) phosphate (TDCPP) 13674-87-8 October 28, 2011
Trp-P-1 (Tryptophan-P-1) 62450-06-0 April 1, 1988
Trp-P-2 (Tryptophan-P-2) 62450-07-1 April 1, 1988
Trypan blue (commercial grade) 72-57-1 October 1, 1989
Unleaded gasoline (wholly vaporized) -- April 1, 1988
Uracil mustard 66-75-1 April 1, 1988
Urethane (Ethyl carbamate) 51-79-6 January 1, 1988
Vanadium pentoxide (orthorhombic crystalline form) 1314-62-1 February 11, 2005
Vinclozolin 50471-44-8 August 20, 1999
Vinyl bromide 593-60-2 October 1, 1988
Vinyl chloride 75-01-4 February 27, 1987
4-Vinylcyclohexene 100-40-3 May 1, 1996
4-Vinyl-1-cyclohexene diepoxide (Vinyl cyclohexene dioxide) 106-87-6 July 1, 1990
Vinyl fluoride 75-02-5 May 1, 1997
Vinylidene chloride (1,1-Dichloroethylene) 75-35-4 December 29, 2017
Vinyl trichloride (1,1,2-Trichloroethane) 79-00-5 October 1, 1990
Wood dust -- December 18, 2009
2,6-Xylidine (2,6-Dimethylaniline) 87-62-7 January 1, 1991
Zalcitabine 7481-89-2 August 7, 2009
Zidovudine (AZT) 30516-87-1 December 18, 2009
Zileuton 111406-87-2 December 22, 2000

(c) Chemicals known to the state to cause reproductive toxicity.

Chemical Type of Reproductive Toxicity CAS Number Date
Abiraterone acetate developmental, female, male 154229-18-2 April 8, 2016
Acetazolamide developmental 59-66-5 August 20, 1999
Acetohydroxamic acid developmental 546-88-3 April 1, 1990
Acrylamide developmental, male 79-06-1 February 25, 2011
Actinomycin D developmental 50-76-0 October 1, 1992
All-trans retinoic acid developmental 302-79-4 January 1, 1989
Alprazolam developmental 28981-97-7 July 1, 1990
Altretamine developmental, male 645-05-6 August 20, 1999
Amantadine hydrochloride developmental 665-66-7 February 27, 2001
Amikacin sulfate developmental 39831-55-5 July 1, 1990
Aminoglutethimide developmental 125-84-8 July 1, 1990
Aminoglycosides developmental -- October 1, 1992
Aminopterin developmental, female 54-62-6 July 1, 1987
Amiodarone hydrochloride developmental, female, male 19774-82-4 August 26, 1997
Amitraz developmental 33089-61-1 March 30, 1999
Amoxapine developmental 14028-44-5 May 15, 1998
Anabolic steroids female, male -- April 1, 1990
Angiotensin converting enzyme (ACE) inhibitors developmental -- October 1, 1992
Anisindione developmental 117-37-3 October 1, 1992
Arsenic (inorganic oxides) developmental -- May 1, 1997
Aspirin (NOTE: It is especially important not to use aspirin during the last three months of pregnancy, unless specifically directed to do so by a physician because it may cause problems in the unborn child or complications during delivery.) developmental, female 50-78-2 July 1, 1990
Atenolol developmental 29122-68-7 August 26, 1997
Atrazine developmental, female 1912-24-9 July 15, 2016
Auranofin developmental 34031-32-8 January 29, 1999
Avermectin B1 (Abamectin) developmental 71751-41-2 December 3, 2010
Azathioprine developmental 446-86-6 September 1, 1996
Barbiturates developmental -- October 1, 1992
Beclomethasone dipropionate developmental 5534-09-8 May 15, 1998
Benomyl developmental, male 17804-35-2 July 1, 1991
Benzene developmental, male 71-43-2 December 26, 1997
Benzodiazepines developmental -- October 1, 1992
Benzphetamine hydrochloride developmental 5411-22-3 April 1, 1990
Bevacizumab developmental 216974-75-3 March 8, 2019
Bischloroethyl nitrosourea (BCNU) (Carmustine) developmental 154-93-8 July 1, 1990
Bisphenol A (BPA) female 80-05-7 May 11, 2015
Bisphenol A (BPA) developmental 80-05-7 December 18, 2020
Bisphenol S (BPS) female 80-09-1 December 29, 2023
Bromacil lithium salt developmental 53404-19-6 May 18, 1999
male January 17, 2003
1-Bromopropane (1-BP) developmental, female, male 106-94-5 December 7, 2004
2-Bromopropane (2-BP) female, male 75-26-3 May 31, 2005
Bromoxynil developmental 1689-84-5 October 1, 1990
Bromoxynil octanoate developmental 1689-99-2 May 18, 1999
Butabarbital sodium developmental 143-81-7 October 1, 1992
1,3-Butadiene developmental, female, male 106-99-0 April 16, 2004
1,4-Butanediol dimethanesulfonate (Busulfan) developmental 55-98-1 January 1, 1989
Butyl benzyl phthalate (BBP) developmental 85-68-7 December 2, 2005
Cadmium developmental, male -- May 1, 1997
Cannabis (marijuana) smoke developmental -- January 3, 2020
Carbamazepine developmental 298-46-4 January 29, 1999
Carbaryl developmental, female, male 63-25-2 August 7, 2009
Carbon disulfide developmental, female, male 75-15-0 July 1, 1989
Carbon monoxide developmental 630-08-0 July 1, 1989
Carboplatin developmental 41575-94-4 July 1, 1990
Chenodiol developmental 474-25-9 April 1, 1990
Chlorambucil developmental 305-03-3 January 1, 1989
Chlorcyclizine hydrochloride developmental 1620-21-9 July 1, 1987
Chlordecone (Kepone) developmental 143-50-0 January 1, 1989
Chlordiazepoxide developmental 58-25-3 January 1, 1992
Chlordiazepoxide hydrochloride developmental 438-41-5 January 1, 1992
1-(2-Chloroethyl)-3-cyclohexyl-l-nitrosourea (CCNU) (Lomustine) developmental 13010-47-4 July 1, 1990
Chloroform developmental 67-66-3 August 7, 2009
2-Chloropropionic acid male 598-78-7 August 7, 2009
Chlorpyrifos developmental 2921-88-2 December 15, 2017
Chromium (hexavalent compounds) developmental, female, male -- December 19, 2008
Cidofovir developmental, female, male 113852-37-2 January 29, 1999
Cladribine developmental 4291-63-8 September 1, 1996
Clarithromycin developmental 81103-11-9 May 1, 1997
Clobetasol propionate developmental, female 25122-46-7 May 15, 1998
Clomiphene citrate developmental 50-41-9 April 1, 1990
Clorazepate dipotassium developmental 57109-90-7 October 1, 1992
Cocaine developmental, female 50-36-2 July 1, 1989
Codeine phosphate developmental 52-28-8 May 15, 1998
Colchicine developmental, male 64-86-8 October 1, 1992
Conjugated estrogens developmental -- April 1, 1990
Cyanazine developmental 21725-46-2 April 1, 1990
Cycloate developmental 1134-23-2 March 19, 1999
Cycloheximide developmental 66-81-9 January 1, 1989
Cyclophosphamide (anhydrous) developmental, female, male 50-18-0 January 1, 1989
Cyclophosphamide (hydrated) developmental, female, male 6055-19-2 January 1, 1989
Cyhexatin developmental 13121-70-5 January 1, 1989
Cytarabine developmental 147-94-4 January 1, 1989
Dacarbazine developmental 4342-03-4 January 29, 1999
Danazol developmental 17230-88-5 April 1, 1990
Daunorubicin hydrochloride developmental 23541-50-6 July 1, 1990
2,4-D butyric acid male 94-82-6 June 18, 1999
o,p'-DDT developmental, female, male 789-02-6 May 15, 1998
p,p'-DDT developmental, female, male 50-29-3 May 15, 1998
Demeclocycline hydrochloride (internal use) developmental 64-73-3 January 1, 1992
Des-ethyl atrazine (DEA) developmental, female 6190-65-4 July 15, 2016
Des-isopropyl atrazine (DIA) developmental, female 1007-28-9 July 15, 2016
2,4-Diamino-6-chloro-s-triazine (DACT) developmental, female 3397-62-4 July 15, 2016
Diazepam developmental 439-14-5 January 1, 1992
Diazoxide developmental 364-98-7 February 27, 2001
1,2-Dibromo-3-chloropropane (DBCP) male 96-12-8 February 27, 1987
Dichloroacetic acid developmental, male 79-43-6 August 7, 2009
1,1-Dichloro-2,2-bis(p-chlorophenyl)-ethylene (DDE) developmental, male 72-55-9 March 30, 2010
Dichlorophene developmental 97-23-4 April 27, 1999
Dichlorphenamide developmental 120-97-8 February 27, 2001
Diclofop methyl developmental 51338-27-3 March 5, 1999
Dicumarol developmental 66-76-2 October 1, 1992
Di(2-ethylhexyl)phthalate (DEHP) developmental, male 117-81-7 October 24, 2003
Diethylstilbestrol (DES) developmental 56-53-1 July 1, 1987
Diflunisal developmental, female 22494-42-4 January 29, 1999
Dihydroergotamine mesylate developmental 6190-39-2 May 1, 1997
Di-isodecyl phthalate (DIDP) developmental 68515-49-1/ April 20, 2007
26761-40-0
Diltiazem hydrochloride developmental 33286-22-5 February 27, 2001
N,N-Dimethylacetamide developmental, male 127-19-5 May 21, 2010
Di-n-butyl phthalate (DBP) developmental, female, male 84-74-2 December 2, 2005
Di-n-hexyl phthalate (DnHP) female, male 84-75-3 December 2, 2005
m-Dinitrobenzene male 99-65-0 July 1, 1990
o-Dinitrobenzene male 528-29-0 July 1, 1990
p-Dinitrobenzene male 100-25-4 July 1, 1990
Dinitrotoluene (technical grade) female, male -- August 20, 1999
2,4-Dinitrotoluene male 121-14-2 August 20, 1999
2,6-Dinitrotoluene male 606-20-2 August 20, 1999
Dinocap developmental 39300-45-3 April 1, 1990
Dinoseb developmental, male 88-85-7 January 1, 1989
Diphenylhydantoin (Phenytoin) developmental 57-41-0 July 1, 1987
Disodium cyanodithioimidocarbonate developmental 138-93-2 March 30, 1999
Doxorubicin hydrochloride (Adriamycin) developmental, male 25316-40-9 January 29, 1999
Doxycycline (internal use) developmental 564-25-0 July 1, 1990
Doxycycline calcium (internal use) developmental 94088-85-4 January 1, 1992
Doxycycline hyclate (internal use) developmental 24390-14-5 October 1, 1991
Doxycycline monohydrate (internal use) developmental 17086-28-1 October 1, 1991
Endrin developmental 72-20-8 May 15, 1998
Environmental tobacco smoke (ETS) developmental -- June 9, 2006
Epichlorohydrin male 106-89-8 September 1, 1996
Ergotamine tartrate developmental 379-79-3 April 1, 1990
Estropipate developmental 7280-37-7 August 26, 1997
Ethionamide developmental 536-33-4 August 26, 1997
Ethyl alcohol in alcoholic beverages developmental -- October 1, 1987
Ethyl dipropylthiocarbamate developmental 759-94-4 April 27, 1999
Ethylene dibromide developmental, male 106-93-4 May 15, 1998
Ethylene glycol (ingested) developmental 107-21-1 June 19, 2015
Ethylene glycol monoethyl ether developmental, male 110-80-5 January 1, 1989
Ethylene glycol monoethyl ether acetate developmental, male 111-15-9 January 1, 1993
Ethylene glycol monomethyl ether developmental, male 109-86-4 January 1, 1989
Ethylene glycol monomethyl ether acetate developmental, male 110-49-6 January 1, 1993
Ethylene oxide female 75-21-8 February 27, 1987
developmental, male August 7, 2009
Ethylene thiourea developmental 96-45-7 January 1, 1993
Etodolac developmental, female 41340-25-4 August 20, 1999
Etoposide developmental 33419-42-0 July 1, 1990
Etretinate developmental 54350-48-0 July 1, 1987
Fenoxaprop ethyl developmental 66441-23-4 March 26, 1999
Filgrastim developmental 121181-53-1 February 27, 2001
Fluazifop butyl developmental 69806-50-4 November 6, 1998
Flunisolide developmental, female 3385-03-3 May 15, 1998
Fluorouracil developmental 51-21-8 January 1, 1989
Fluoxymesterone developmental 76-43-7 April 1, 1990
Flurazepam hydrochloride developmental 1172-18-5 October 1, 1992
Flurbiprofen developmental, female 5104-49-4 August 20, 1999
Flutamide developmental 13311-84-7 July 1, 1990
Fluticasone propionate developmental 80474-14-2 May 15, 1998
Fluvalinate developmental 69409-94-5 November 6, 1998
Ganciclovir developmental, male 82410-32-0 August 26, 1997
Ganciclovir sodium developmental, male 107910-75-8 August 26, 1997
Gemfibrozil female, male 25812-30-0 August 20, 1999
Goserelin acetate developmental, female, male 65807-02-5 August 26, 1997
Halazepam developmental 23092-17-3 July 1, 1990
Halobetasol propionate developmental 66852-54-8 August 20, 1999
Haloperidol developmental, female 52-86-8 January 29, 1999
Halothane developmental 151-67-7 September 1, 1996
Heptachlor developmental 76-44-8 August 20, 1999
Hexachlorobenzene developmental 118-74-1 January 1, 1989
Hexafluoroacetone male 684-16-2 August 1, 2008
Hexamethylphosphoramide developmental, male 680-31-9 October 1, 1994
n-Hexane male 110-54-3 December 15, 2017
2,5-Hexanedione male 110-13-4 December 4, 2015
Histrelin acetate developmental -- May 15, 1998
Hydramethylnon developmental, male 67485-29-4 March 5, 1999
Hydrogen cyanide (HCN) male -- July 5, 2013
and cyanide salts (CN salts)
Hydroxyurea developmental 127-07-1 May 1, 1997
Idarubicin hydrochloride developmental, male 57852-57-0 August 20, 1999
Ifosfamide developmental 3778-73-2 July 1, 1990
Iodine-131 developmental 10043-66-0 January 1, 1989
Isotretinoin developmental 4759-48-2 July 1, 1987
Lead developmental, female, male -- February 27, 1987
Leuprolide acetate developmental, female, male 74381-53-6 August 26, 1997
Levodopa developmental 59-92-7 January 29, 1999
Levonorgestrel implants female 797-63-7 May 15, 1998
Linuron developmental 330-55-2 March 19, 1999
Lithium carbonate developmental 554-13-2 January 1, 1991
Lithium citrate developmental 919-16-4 January 1, 1991
Lorazepam developmental 846-49-1 July 1, 1990
Lovastatin developmental 75330-75-5 October 1, 1992
Mebendazole developmental 31431-39-7 August 20, 1999
Medroxyprogesterone acetate developmental 71-58-9 April 1, 1990
Megestrol acetate developmental 595-33-5 January 1, 1991
Melphalan developmental 148-82-3 July 1, 1990
Menotropins developmental 9002-68-0 April 1, 1990
Meprobamate developmental 57-53-4 January 1, 1992
Mercaptopurine developmental 6112-76-1 July 1, 1990
Mercury and mercury compounds developmental -- July 1, 1990
Methacycline hydrochloride developmental 3963-95-9 January 1, 1991
Metham sodium developmental 137-42-8 May 15, 1998
Methanol developmental 67-56-1 March 16, 2012
Methazole developmental 20354-26-1 December 1, 1999
Methimazole developmental 60-56-0 July 1, 1990
Methotrexate developmental 59-05-2 January 1, 1989
Methotrexate sodium developmental 15475-56-6 April 1, 1990
Methyl bromide as a structural fumigant developmental 74-83-9 January 1, 1993
Methyl chloride developmental 74-87-3 March 10, 2000
male August 7, 2009
Methyl isobutyl ketone (MIBK) developmental 108-10-1 March 28, 2014
Methyl isocyanate (MIC) developmental, male 624-83-9 November 12, 2010
Methyl mercury developmental -- July 1, 1987
Methyl-n-butyl ketone male 591-78-6 August 7, 2009
developmental December 4, 2015
N-Methylpyrrolidone developmental 872-50-4 June 15, 2001
Methyltestosterone developmental 58-18-4 April 1, 1990
Metiram developmental 9006-42-2 March 30, 1999
Midazolam hydrochloride developmental 59467-96-8 July 1, 1990
Minocycline hydrochloride (internal use) developmental 13614-98-7 January 1, 1992
Misoprostol developmental 59122-46-2 April 1, 1990
Mitoxantrone hydrochloride developmental 70476-82-3 July 1, 1990
Molinate developmental, female, male 2212-67-1 December 11, 2009
Myclobutanil developmental, male 88671-89-0 April 16, 1999
Nabam developmental 142-59-6 March 30, 1999
Nafarelin acetate developmental 86220-42-0 April 1, 1990
Neomycin sulfate (internal use) developmental 1405-10-3 October 1, 1992
Netilmicin sulfate developmental 56391-57-2 July 1, 1990
Nickel carbonyl developmental 13463-39-3 September 1, 1996
Nickel (soluble compounds) developmental, male -- October 26, 2018
Nicotine developmental 54-11-5 April 1, 1990
Nifedipine developmental, female, male 21829-25-4 January 29, 1999
Nimodipine developmental 66085-59-4 April 24, 2001
Nitrapyrin developmental 1929-82-4 March 30, 1999
Nitrobenzene male 98-95-3 March 30, 2010
Nitrofurantoin male 67-20-9 April 1, 1991
Nitrogen mustard (Mechlorethamine) developmental 51-75-2 January 1, 1989
Nitrogen mustard hydrochloride (Mechlorethamine hydrochloride) developmental 55-86-7 July 1, 1990
Nitrous oxide developmental, female 10024-97-2 August 1, 2008
Norethisterone (Norethindrone) developmental 68-22-4 April 1, 1990
Norethisterone acetate (Norethindrone acetate) developmental 51-98-9 October 1, 1991
Norethisterone (Norethindrone)/Ethinyl estradiol developmental 68-22-4/57-63-6 April 1, 1990
Norethisterone (Norethindrone)/Mestranol developmental 68-22-4/72-33-3 April 1, 1990
Norgestrel developmental 6533-00-2 April 1, 1990
Oxadiazon developmental 19666-30-9 May 15, 1998
Oxazepam developmental 604-75-1 October 1, 1992
Oxydemeton methyl female, male 301-12-2 November 6, 1998
Oxymetholone developmental 434-07-1 May 1, 1997
Oxytetracycline (internal use) developmental 79-57-2 January 1, 1991
Oxytetracycline hydrochloride (internal use) developmental 2058-46-0 October 1, 1991
Oxythioquinox (Chinomethionat) developmental 2439-01-2 November 6, 1998
Paclitaxel developmental, female, male 33069-62-4 August 26, 1997
Paramethadione developmental 115-67-3 July 1, 1990
Penicillamine developmental 52-67-5 January 1, 1991
Pentobarbital sodium developmental 57-33-0 July 1, 1990
Pentostatin developmental 53910-25-1 September 1, 1996
Perfluorononanoic acid (PFNA) and its salts male - December 31, 2021
Perfluorooctane 9ulfonate (PFOS) developmental 1763-23-1 November 10, 2017
Perfluorooctanoic acid (PFOA) developmental 335-67-1 November 10, 2017
Pertuzumab developmental 380610-27-5 January 27, 2017
Phenacemide developmental 63-98-9 July 1, 1990
Phenprocoumon developmental 435-97-2 October 1, 1992
Phenylphosphine male 638-21-1 August 7, 2009
Pimozide developmental, female 2062-78-4 August 20, 1999
Pipobroman developmental 54-91-1 July 1, 1990
Plicamycin developmental 18378-89-7 April 1, 1990
Polybrominated biphenyls developmental -- October 1, 1994
Polychlorinated biphenyls developmental -- January 1, 1991
Potassium dimethyldithiocarbamate developmental 128-03-0 March 30, 1999
Pravastatin sodium developmental 81131-70-6 March 3, 2000
Prednisolone sodium phosphate developmental 125-02-0 August 20, 1999
Procarbazine hydrochloride developmental 366-70-1 July 1, 1990
Propargite developmental 2312-35-8 June 15, 1999
Propazine developmental, female 139-40-2 July 15, 2016
Propylthiouracil developmental 51-52-5 July 1, 1990
Pyrimethamine developmental 58-14-0 January 29, 1999
Quazepam developmental 36735-22-5 August 26, 1997
Quizalofop-ethyl male 76578-14-8 December 24, 1999
Resmethrin developmental 10453-86-8 November 6, 1998
Retinol/retinyl esters, when in daily dosages in excess of 10,000 IU, or 3,000 retinol equivalents. (NOTE: Retinol/retinyl esters are required and essential for maintenance of normal reproductive function. The recommended daily level during pregnancy is 8,000 IU.) developmental -- July 1, 1989
Ribavirin developmental 36791-04-5 April 1, 1990
male 36791-04-5 February 27, 2001
Rifampin developmental, female 13292-46-1 February 27, 2001
Secobarbital sodium developmental 309-43-3 October 1, 1992
Sermorelin acetate developmental -- August 20, 1999
Simazine developmental, female 122-34-9 July 15, 2016
Sodium dimethyldithiocarbamate developmental 128-04-1 March 30, 1999
Sodium fluoroacetate male 62-74-8 November 6, 1998
Streptomycin sulfate developmental 3810-74-0 January 1, 1991
Streptozocin (streptozotocin) developmental, female, male 18883-66-4 August 20, 1999
Sulfasalazine (Salicylazosulfapyridine) male 599-79-1 January 29, 1999
Sulfur dioxide developmental 7446-09-5 July 29, 2011
Sulindac developmental, female 38194-50-2 January 29, 1999
Tamoxifen citrate developmental 54965-24-1 July 1, 1990
Temazepam developmental 846-50-4 April 1, 1990
Teniposide developmental 29767-20-2 September 1, 1996
Terbacil developmental 5902-51-2 May 18, 1999
Testosterone cypionate developmental 58-20-8 October 1, 1991
Testosterone enanthate developmental 315-37-7 April 1, 1990
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) developmental 1746-01-6 April 1, 1991
Tetracycline (internal use) developmental 60-54-8 October 1, 1991
Tetracyclines (internal use) developmental -- October 1, 1992
Tetracycline hydrochloride (internal use) developmental 64-75-5 January 1, 1991
[DELTA]9-Tetrahydrocannabinol ([DELTA]9-THC; delta-9-THC) developmental -- January 3, 2020
Thalidomide developmental 50-35-1 July 1, 1987
Thioguanine developmental 154-42-7 July 1, 1990
Thiophanate methyl female, male 23564-05-8 May 18, 1999
Tobacco smoke (primary) developmental, female, male -- April 1, 1988
Tobramycin sulfate developmental 49842-07-1 July 1, 1990
Toluene developmental 108-88-3 January 1, 1991
Topiramate developmental 97240-79-4 November 27, 2015
Triadimefon developmental, female, male 43121-43-3 March 30, 1999
Triazolam developmental 28911-01-5 April 1, 1990
Tributyltin methacrylate developmental 2155-70-6 December 1, 1999
Trichloroethylene developmental, male 79-01-6 January 31, 2014
Trientine hydrochloride developmental 38260-01-4 February 27, 2001
Triforine developmental 26644-46-2 June 18, 1999
Trilostane developmental 13647-35-3 April 1, 1990
Trimethadione developmental 127-48-0 January 1, 1991
Trimetrexate glucuronate developmental 82952-64-5 August 26, 1997
Triphenyltin hydroxide developmental 76-87-9 March 15, 2002
Uracil mustard developmental, female, male 66-75-1 January 1, 1992
Urethane developmental 51-79-6 October 1, 1994
Urofollitropin developmental 97048-13-0 April 1, 1990
Valproate (Valproic acid) developmental 99-66-1 July 1, 1987
Vinblastine sulfate developmental 143-67-9 July 1, 1990
Vinclozolin developmental 50471-44-8 May 15, 1998
Vincristine sulfate developmental 2068-78-2 July 1, 1990
4-Vinylcyclohexene female 100-40-3 August 7, 2009
Vinyl cyclohexene dioxide (4-Vinyl-l-cyclohexene diepoxide) female 106-87-6 August 1, 2008
Visomodegib developmental, female, male 879085-55-9 January 27, 2017
Warfarin developmental 81-81-2 July 1, 1987
Zileuton developmental, female 111406-87-2 December 22, 2000
Date: December 29, 2023

Note: Authority cited: Section 25249.8, Health and Safety Code. Reference: Section 25249.8, Health and Safety Code.

Note: Authority cited: Section 25249.8, Health and Safety Code. Reference: Section 25249.8, Health and Safety Code.

Disclaimer: These regulations may not be the most recent version. California may have more current or accurate information. We make no warranties or guarantees about the accuracy, completeness, or adequacy of the information contained on this site or the information linked to on the state site. Please check official sources.
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