Supplemental Evidence and Data Request on Mindfulness-Based Interventions for Mental Health and Wellbeing in Children and Adolescents: A Systematic Review, 54822-54824 [2024-14573]
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Federal Register / Vol. 89, No. 127 / Tuesday, July 2, 2024 / Notices
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[FR Doc. 2024–14575 Filed 7–1–24; 8:45 am]
BILLING CODE P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Agency for Healthcare Research and
Quality
Supplemental Evidence and Data
Request on Mindfulness-Based
Interventions for Mental Health and
Wellbeing in Children and
Adolescents: A Systematic Review
Agency for Healthcare Research
and Quality (AHRQ), HHS.
ACTION: Request for supplemental
evidence and data submission.
AGENCY:
The Agency for Healthcare
Research and Quality (AHRQ) is seeking
scientific information submissions from
the public. Scientific information is
being solicited to inform our review on
Mindfulness-Based Interventions for
Mental Health and Wellbeing in
Children and Adolescents: A Systematic
Review, which is currently being
conducted by AHRQ’s Evidence-based
Practice Centers (EPC) Program. Access
to published and unpublished pertinent
scientific information will improve the
quality of this review.
DATES: Submission Deadline on or
before August 1, 2024.
ADDRESSES:
Email submissions: epc@ahrq.hhs.gov
Print submissions:
Mailing Address: Center for Evidence
and Practice Improvement, Agency for
Healthcare Research and Quality,
ATTN: EPC SEADs Coordinator, 5600
Fishers Lane, Mail Stop 06E53A,
Rockville, MD 20857.
Shipping Address (FedEx, UPS, etc.):
Center for Evidence and Practice
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Improvement, Agency for Healthcare
Research and Quality, ATTN: EPC
SEADs Coordinator, 5600 Fishers Lane,
Mail Stop 06E77D, Rockville, MD
20857.
FOR FURTHER INFORMATION CONTACT:
Kelly Carper, telephone: 301–427–1656
or email: epc@ahrq.hhs.gov.
SUPPLEMENTARY INFORMATION: The
Agency for Healthcare Research and
Quality has commissioned the
Evidence-based Practice Centers (EPC)
Program to complete a review of the
evidence for Mindfulness-Based
Interventions for Mental Health and
Wellbeing in Children and Adolescents:
A Systematic Review. AHRQ is
conducting this review pursuant to
section 902 of the Public Health Service
Act, 42 U.S.C. 299a.
The EPC Program is dedicated to
identifying as many studies as possible
that are relevant to the questions for
each of its reviews. In order to do so, we
are supplementing the usual manual
and electronic database searches of the
literature by requesting information
from the public (e.g., details of studies
conducted). We are looking for studies
that report on Mindfulness-Based
Interventions for Mental Health and
Wellbeing in Children and Adolescents:
A Systematic Review. The entire
research protocol is available online at:
https://effectivehealthcare.ahrq.gov/
products/ped-mindfulness/protocol
This is to notify the public that the
EPC Program would find the following
information on Mindfulness-Based
Interventions for Mental Health and
Wellbeing in Children and Adolescents:
A Systematic Review helpful:
D A list of completed studies that
your organization has sponsored for this
topic. In the list, please indicate
whether results are available on
ClinicalTrials.gov along with the
ClinicalTrials.gov trial number.
D For completed studies that do not
have results on ClinicalTrials.gov, a
summary, including the following
elements, if relevant: study number,
study period, design, methodology,
indication and diagnosis, inclusion and
exclusion criteria, primary and
secondary outcomes, baseline
characteristics, number of patients
screened/eligible/enrolled/lost to
follow-up/withdrawn/analyzed,
effectiveness/efficacy, and safety results.
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D A list of ongoing studies that your
organization has sponsored for this
topic. In the list, please provide the
ClinicalTrials.gov trial number or, if the
trial is not registered, the protocol for
the study including, if relevant, a study
number, the study period, design,
methodology, indication and diagnosis,
inclusion and exclusion criteria, and
primary and secondary outcomes.
D Description of whether the above
studies constitute ALL Phase II and
above clinical trials sponsored by your
organization for this topic and an index
outlining the relevant information in
each submitted file.
Your contribution is very beneficial to
the Program. Materials submitted must
be publicly available or able to be made
public. Materials that are considered
confidential; marketing materials; study
types not included in the review; or
information on topics not included in
the review cannot be used by the EPC
Program. This is a voluntary request for
information, and all costs for complying
with this request must be borne by the
submitter.
The draft of this review will be posted
on AHRQ’s EPC Program website and
available for public comment for a
period of 4 weeks. If you would like to
be notified when the draft is posted,
please sign up for the email list at:
https://effectivehealthcare.ahrq.gov/
email-updates.
The review will answer the following
questions. This information is provided
as background. AHRQ is not requesting
that the public provide answers to these
questions.
Key Questions (KQ)
KQ 1. What are the benefits and harms
of mindfulness-based interventions
in the general child and adolescent
populations?
KQ 2. What are the benefits and harms
of mindfulness-based interventions
in children and adolescents
diagnosed with anxiety and/or
depression?
KQ 3. What are the benefits and harms
of mindfulness-based interventions
in children and adolescents with a
chronic condition who are at risk
for elevated symptoms of anxiety
and/or depression?
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Federal Register / Vol. 89, No. 127 / Tuesday, July 2, 2024 / Notices
54823
PICOTS (POPULATIONS, INTERVENTIONS, COMPARATORS, OUTCOMES, TIMING, AND SETTING)
Inclusion criteria
Exclusion criteria
Population ..................................
KQ 1. Children and adolescents aged 3 to 18 years without
known anxiety and/or depression.
KQ 2. Children and adolescents aged 3 to 18 years with a diagnosis of depression and/or anxiety.
KQ 3. Children and adolescents aged 3 to 18 years with a
chronic condition who are at risk for elevated symptoms of or
being diagnosed with anxiety and/or depression.
Definition of chronic physical conditions: Medical physical conditions (i.e., conditions that primarily affect the body’s systems
and functions) that persist for one year or longer and require
ongoing medical attention, limit activities of daily living, or
both.
Interventions ..............................
KQ 1–3 ..........................................................................................
In addition to the minimum requirements identified above:
• Mindfulness-based intervention, provided alone or in addition
to other therapies.
• Mindfulness is the primary component for multicomponent
interventions (as a part of behavioral and similar non-pharmacological strategies), meaning that the intervention must be
centered around mindfulness (e.g., the majority of the sessions or focus are mindfulness-based).
• A mindfulness instructor (e.g., therapist, teacher) must have
some training in providing mindfulness. We do not specify the
required minimum training.
• Clear specification of repeated practice (e.g., more than one
session with an instructor, or repeated self-directed exercises
after at least one initial session with an instructor).
Examples of other therapies include structured mindfulness programs and mindfulness-based therapies such as:
• Mindfulness-based Stress Reduction ........................................
• Mindfulness-based Cognitive Therapy ......................................
• Acceptance and Commitment Therapy .....................................
Components of programs, if they are intentionally used to promote mindfulness principles and meet other criteria, may include:
• Relaxation techniques ...............................................................
• Meditation ..................................................................................
• Mindful breathing .......................................................................
• Guided imagery .........................................................................
• Visualization ...............................................................................
KQ 1. Usual care, enhanced usual care, waitlist control, sham,
attention control, or no active intervention.
KQ 2–3. Usual care, enhanced usual care, waitlist control,
sham, attention control, no active intervention, or conventional
therapies (i.e., pharmacotherapy for anxiety and/or depression
[see Table 2], behavioral interventions b).
KQ 1–3 ..........................................................................................
Primary outcomes (children and adolescents outcomes) .............
• Quality of life (e.g., PedsQL, KIDSCREEN, CHQ, ITQOL,
PQ–LES–Q).
• General and social functioning (e.g., SDQ, SSIS, CGI–I,
CGAS), including behavior problems (e.g., ECBI, CBCL,
SDQ), coping skills (e.g., CSI–CA, CCSC, RSQ), executive
functioning (e.g., BRIEF), academic performance (e.g., WIAT,
Woodcock-Johnson Tests of Achievement).
• Disability (e.g., VABS, FDI, days of missed school).
• Depression (e.g., CDI, BDI, MFQ, CES–D, CDRS–R, RADS,
PHQ–A, PI–ED), diagnosis (KQs 2 and 3 only), and remission
and response (KQs 1 and 3).
• Anxiety (e.g., SCARED, MASC, SCAS, CAIS, GAD–7, PHQ–
A, PI–ED), diagnosis (KQs 2 and 3 only), and remission and
response (KQs 1 and 3).
• Any reported adverse events or unintended negative consequences attributed to treatment.
Additional outcomes (children and adolescents outcomes).
• Acceptance of experiences in the present moment (e.g.,
CAMM).
• Autonomic arousal (e.g., SCL, HRV).
• Executive functioning (e.g., BRIEF).
• Subjective well-being (e.g., PANAS–C, SLSS).
• Substance use.
Studies with ≥20% of participants in the following groups and do
not report findings by population.
• In institutions (e.g., psychiatric inpatients, long-term care facilities).
• Diagnosed with advanced neurodevelopmental disorders
(e.g., severe autism spectrum disorders [for example, level 3
on DSM–5], severe attention-deficit/hyperactivity disorder
[e.g., based on DSM–5 definition], severe learning disorders
[e.g., more than 2 standard deviations below the mean in one
or more areas of cognitive processing related to the specific
learning disorder]).
• With major behavioral or emotional dysregulation (e.g., conduct disorder, oppositional defiant disorder, disruptive mood
dysregulation disorder).a
• With substance use disorder.
We will exclude studies with MBIs designed and/or administered
only to parents/caregivers, as well as interventions administered by parents/caregivers.
We will exclude studies designed to treat test or sports performance anxiety, anxiety associated with medical/dental procedures and with interventions for specific high-risk exposures
such as for post-sexual assault or another traumatic event.
Pharmacologic interventions or traditional psychotherapies alone
(e.g., cognitive-behavioral therapy, play therapy, dialectical
behavior therapy, parent-child interaction therapy) and integrative therapies alone including acupuncture/acupressure,
expressive therapies, exercise, yoga, Tai Chi, biofeedback,
hypnotherapy, massage, chiropractic care, homeopathy, diets
(e.g., gluten-free diet), traditional Chinese medicine, and
Ayurveda.
Comparators ..............................
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Outcomes ..................................
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Other interventions not listed in the ‘‘included’’ list.
Other mindfulness-based interventions (i.e., comparative effectiveness of MBIs).
Other outcomes, parent/caregiver outcomes.
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54824
Federal Register / Vol. 89, No. 127 / Tuesday, July 2, 2024 / Notices
PICOTS (POPULATIONS, INTERVENTIONS, COMPARATORS, OUTCOMES, TIMING, AND SETTING)—Continued
Inclusion criteria
Timing ........................................
Setting ........................................
Study Design .............................
Exclusion criteria
• Psychological flexibility (e.g., AFQ–Y, AAQ).
• Healthcare utilization.
• A minimum of 4 weeks since the beginning of the intervention
or baseline assessment (if the intervention start cannot be determined) for all outcomes except for harms.
• We will extract harms reported at any followup, regardless of
the duration since the intervention start or baseline assessment.
KQ 1–3 ..........................................................................................
• Administered in outpatient health care or community settings
(e.g., schools, residential).
• Trials conducted in countries rated as ‘‘very high’’ on the
2019 Human Development Index (as defined by the United
Nations Development Program).
• Randomized controlled trials (individually or site-randomized),
with individually randomized trials reporting outcomes for a
minimum of 10 participants per treatment arm.
• Period 1 data from crossover RCTs.
• Published in English-language.
• Published in 2010 or later.
Mid-intervention assessment times.
In-patient, ED/EMS, and psychiatric subacute settings (e.g., partial hospitalization programs, intensive outpatient programs).
Other study designs.
Abbreviations: AAQ = Acceptance and Action Questionnaire; AFQ–Y = Avoidance and Fusion Questionnaire for Youth; BDI = Beck Depression Inventory; BRIEF =
Behavior Rating Inventory of Executive Function; CAIS = Child Anxiety Impact Scale; CAMM = Child and Adolescent Mindfulness Measure; CBCL = Child Behavior
Checklist; CCSC = Children’s Coping Strategies Checklist; CDI = Children’s Depression Inventory; CDRS–R = Children’s Depression Rating Scale–Revised; CES–D
= Center for Epidemiologic Studies Depression Scale; CGAS = Children’s Global Assessment Scale; CGI–I = Clinical Global Impression-Improvement Scale; CHQ =
Child Health Questionnaire; CSI–CA = Coping Strategies Inventory for Children and Adolescents; ED/EMS = emergency department/emergency medical services;
ECBI = Eyberg Child Behavior Inventory; FDI = Functional Disability Inventory Child Form; GAD–7 = Generalized Anxiety Disorder scale; HRV = heart rate variability;
ITQOL = Infant/Toddler Quality of Life Questionnaire; KQ = Key Question; MASC = Multidimensional Anxiety Scale for Children; MFQ = Mood and Feelings Questionnaire; NA = not applicable; PedsQL = Pediatric Quality of Life Inventory; PHQ–A = Patient Health Questionnaire for Adolescents; PICOTS = population, interventions,
comparators, outcomes, timing, and setting; PI–ED = Paediatric Index of Emotional Distress; PQ–LES–Q = Perceived Quality of Life Scale; RADS = Reynolds Adolescent Depression Scale; RSQ = Responses to Stress Questionnaire; SCARED = Screen for Child Anxiety Related Emotional Disorders; SCAS = Spence Children’s
Anxiety Scale; SCL = Skin Conductance Level; SDQ = Strengths and Difficulties Questionnaire; SLSS = Students’ Life Satisfaction Scale; SSIS = Social Skills Improvement System; PANAS–C = Positive and Negative Affect Schedule for Children; SWLS = Satisfaction with Life Scale; VABS = Vineland Adaptive Behavior
Scales; WIAT = Wechsler Individual Achievement Test; WISC = Wechsler Intelligence Scale for Children.
a These are reviewed in other AHRQ systematic reviews.
b We defined behavioral interventions as nonpharmacologic strategies intended to enhance outcomes by modifying behavior and/or ways of thinking (e.g.,cognitive
behavioral therapy, coping skills training, behavioral therapy, biofeedback, dialectical behavioral therapy).
Dated: June 27, 2024.
Marquita Cullom,
Associate Director.
[FR Doc. 2024–14573 Filed 7–1–24; 8:45 am]
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Centers for Medicare & Medicaid
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[Document Identifiers: CMS–10849 and
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Agency Information Collection
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The Centers for Medicare &
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an opportunity for the public to
comment on CMS’ intention to collect
information from the public. Under the
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60 days for public comment on the
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To obtain copies of a supporting
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]]>Agencies
[Federal Register Volume 89, Number 127 (Tuesday, July 2, 2024)]
[Notices]
[Pages 54822-54824]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2024-14573]
=======================================================================
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
Agency for Healthcare Research and Quality
Supplemental Evidence and Data Request on Mindfulness-Based
Interventions for Mental Health and Wellbeing in Children and
Adolescents: A Systematic Review
AGENCY: Agency for Healthcare Research and Quality (AHRQ), HHS.
ACTION: Request for supplemental evidence and data submission.
-----------------------------------------------------------------------
SUMMARY: The Agency for Healthcare Research and Quality (AHRQ) is
seeking scientific information submissions from the public. Scientific
information is being solicited to inform our review on Mindfulness-
Based Interventions for Mental Health and Wellbeing in Children and
Adolescents: A Systematic Review, which is currently being conducted by
AHRQ's Evidence-based Practice Centers (EPC) Program. Access to
published and unpublished pertinent scientific information will improve
the quality of this review.
DATES: Submission Deadline on or before August 1, 2024.
ADDRESSES:
Email submissions: [email protected]
Print submissions:
Mailing Address: Center for Evidence and Practice Improvement,
Agency for Healthcare Research and Quality, ATTN: EPC SEADs
Coordinator, 5600 Fishers Lane, Mail Stop 06E53A, Rockville, MD 20857.
Shipping Address (FedEx, UPS, etc.): Center for Evidence and
Practice Improvement, Agency for Healthcare Research and Quality, ATTN:
EPC SEADs Coordinator, 5600 Fishers Lane, Mail Stop 06E77D, Rockville,
MD 20857.
FOR FURTHER INFORMATION CONTACT: Kelly Carper, telephone: 301-427-1656
or email: [email protected].
SUPPLEMENTARY INFORMATION: The Agency for Healthcare Research and
Quality has commissioned the Evidence-based Practice Centers (EPC)
Program to complete a review of the evidence for Mindfulness-Based
Interventions for Mental Health and Wellbeing in Children and
Adolescents: A Systematic Review. AHRQ is conducting this review
pursuant to section 902 of the Public Health Service Act, 42 U.S.C.
299a.
The EPC Program is dedicated to identifying as many studies as
possible that are relevant to the questions for each of its reviews. In
order to do so, we are supplementing the usual manual and electronic
database searches of the literature by requesting information from the
public (e.g., details of studies conducted). We are looking for studies
that report on Mindfulness-Based Interventions for Mental Health and
Wellbeing in Children and Adolescents: A Systematic Review. The entire
research protocol is available online at: https://effectivehealthcare.ahrq.gov/products/ped-mindfulness/protocol
This is to notify the public that the EPC Program would find the
following information on Mindfulness-Based Interventions for Mental
Health and Wellbeing in Children and Adolescents: A Systematic Review
helpful:
[ssquf] A list of completed studies that your organization has
sponsored for this topic. In the list, please indicate whether results
are available on ClinicalTrials.gov along with the ClinicalTrials.gov
trial number.
[ssquf] For completed studies that do not have results on
ClinicalTrials.gov, a summary, including the following elements, if
relevant: study number, study period, design, methodology, indication
and diagnosis, inclusion and exclusion criteria, primary and secondary
outcomes, baseline characteristics, number of patients screened/
eligible/enrolled/lost to follow-up/withdrawn/analyzed, effectiveness/
efficacy, and safety results.
[ssquf] A list of ongoing studies that your organization has
sponsored for this topic. In the list, please provide the
ClinicalTrials.gov trial number or, if the trial is not registered, the
protocol for the study including, if relevant, a study number, the
study period, design, methodology, indication and diagnosis, inclusion
and exclusion criteria, and primary and secondary outcomes.
[ssquf] Description of whether the above studies constitute ALL
Phase II and above clinical trials sponsored by your organization for
this topic and an index outlining the relevant information in each
submitted file.
Your contribution is very beneficial to the Program. Materials
submitted must be publicly available or able to be made public.
Materials that are considered confidential; marketing materials; study
types not included in the review; or information on topics not included
in the review cannot be used by the EPC Program. This is a voluntary
request for information, and all costs for complying with this request
must be borne by the submitter.
The draft of this review will be posted on AHRQ's EPC Program
website and available for public comment for a period of 4 weeks. If
you would like to be notified when the draft is posted, please sign up
for the email list at: https://effectivehealthcare.ahrq.gov/email-updates.
The review will answer the following questions. This information is
provided as background. AHRQ is not requesting that the public provide
answers to these questions.
Key Questions (KQ)
KQ 1. What are the benefits and harms of mindfulness-based
interventions in the general child and adolescent populations?
KQ 2. What are the benefits and harms of mindfulness-based
interventions in children and adolescents diagnosed with anxiety and/or
depression?
KQ 3. What are the benefits and harms of mindfulness-based
interventions in children and adolescents with a chronic condition who
are at risk for elevated symptoms of anxiety and/or depression?
[[Page 54823]]
PICOTS (Populations, Interventions, Comparators, Outcomes, Timing, and
Setting)
------------------------------------------------------------------------
Inclusion criteria Exclusion criteria
------------------------------------------------------------------------
Population.................. KQ 1. Children and Studies with >=20%
adolescents aged 3 of participants in
to 18 years without the following
known anxiety and/ groups and do not
or depression. report findings by
KQ 2. Children and population.
adolescents aged 3 In
to 18 years with a institutions (e.g.,
diagnosis of psychiatric
depression and/or inpatients, long-
anxiety. term care
KQ 3. Children and facilities).
adolescents aged 3 Diagnosed
to 18 years with a with advanced
chronic condition neurodevelopmental
who are at risk for disorders (e.g.,
elevated symptoms severe autism
of or being spectrum disorders
diagnosed with [for example, level
anxiety and/or 3 on DSM-5], severe
depression. attention-deficit/
Definition of hyperactivity
chronic physical disorder [e.g.,
conditions: Medical based on DSM-5
physical conditions definition], severe
(i.e., conditions learning disorders
that primarily [e.g., more than 2
affect the body's standard deviations
systems and below the mean in
functions) that one or more areas
persist for one of cognitive
year or longer and processing related
require ongoing to the specific
medical attention, learning
limit activities of disorder]).
daily living, or With major
both. behavioral or
emotional
dysregulation
(e.g., conduct
disorder,
oppositional
defiant disorder,
disruptive mood
dysregulation
disorder).\a\
With
substance use
disorder.
We will exclude
studies with MBIs
designed and/or
administered only
to parents/
caregivers, as well
as interventions
administered by
parents/caregivers.
We will exclude
studies designed to
treat test or
sports performance
anxiety, anxiety
associated with
medical/dental
procedures and with
interventions for
specific high-risk
exposures such as
for post-sexual
assault or another
traumatic event.
Interventions............... KQ 1-3.............. Pharmacologic
In addition to the interventions or
minimum traditional
requirements psychotherapies
identified above:. alone (e.g.,
Mindfulness- cognitive-
based intervention, behavioral therapy,
provided alone or play therapy,
in addition to dialectical
other therapies. behavior therapy,
Mindfulness parent-child
is the primary interaction
component for therapy) and
multicomponent integrative
interventions (as a therapies alone
part of behavioral including
and similar non- acupuncture/
pharmacological acupressure,
strategies), expressive
meaning that the therapies,
intervention must exercise, yoga, Tai
be centered around Chi, biofeedback,
mindfulness (e.g., hypnotherapy,
the majority of the massage,
sessions or focus chiropractic care,
are mindfulness- homeopathy, diets
based). (e.g., gluten-free
A diet), traditional
mindfulness Chinese medicine,
instructor (e.g., and Ayurveda.
therapist, teacher)
must have some
training in
providing
mindfulness. We do
not specify the
required minimum
training.
Clear
specification of
repeated practice
(e.g., more than
one session with an
instructor, or
repeated self-
directed exercises
after at least one
initial session
with an instructor).
Examples of other
therapies include
structured
mindfulness
programs and
mindfulness-based
therapies such as:.
Mindfulness-
based Stress
Reduction.
Mindfulness-
based Cognitive
Therapy.
Acceptance
and Commitment
Therapy.
Components of
programs, if they
are intentionally
used to promote
mindfulness
principles and meet
other criteria, may
include:.
Relaxation
techniques.
Meditation.
Mindful
breathing.
Guided
imagery.
Visualization.
Comparators................. KQ 1. Usual care, Other interventions
enhanced usual not listed in the
care, waitlist ``included'' list.
control, sham, Other mindfulness-
attention control, based interventions
or no active (i.e., comparative
intervention. effectiveness of
KQ 2-3. Usual care, MBIs).
enhanced usual
care, waitlist
control, sham,
attention control,
no active
intervention, or
conventional
therapies (i.e.,
pharmacotherapy for
anxiety and/or
depression [see
Table 2],
behavioral
interventions \b\).
Outcomes.................... KQ 1-3.............. Other outcomes,
Primary outcomes parent/caregiver
(children and outcomes.
adolescents
outcomes).
Quality of
life (e.g., PedsQL,
KIDSCREEN, CHQ,
ITQOL, PQ-LES-Q).
General and
social functioning
(e.g., SDQ, SSIS,
CGI-I, CGAS),
including behavior
problems (e.g.,
ECBI, CBCL, SDQ),
coping skills
(e.g., CSI-CA,
CCSC, RSQ),
executive
functioning (e.g.,
BRIEF), academic
performance (e.g.,
WIAT, Woodcock-
Johnson Tests of
Achievement).
Disability
(e.g., VABS, FDI,
days of missed
school).
Depression
(e.g., CDI, BDI,
MFQ, CES-D, CDRS-R,
RADS, PHQ-A, PI-
ED), diagnosis (KQs
2 and 3 only), and
remission and
response (KQs 1 and
3).
Anxiety
(e.g., SCARED,
MASC, SCAS, CAIS,
GAD-7, PHQ-A, PI-
ED), diagnosis (KQs
2 and 3 only), and
remission and
response (KQs 1 and
3).
Any
reported adverse
events or
unintended negative
consequences
attributed to
treatment.
Additional outcomes
(children and
adolescents
outcomes).
Acceptance
of experiences in
the present moment
(e.g., CAMM).
Autonomic
arousal (e.g., SCL,
HRV).
Executive
functioning (e.g.,
BRIEF).
Subjective
well-being (e.g.,
PANAS-C, SLSS).
Substance
use.
[[Page 54824]]
Psychological
flexibility (e.g.,
AFQ-Y, AAQ).
Healthcare
utilization.
Timing...................... A minimum Mid-intervention
of 4 weeks since assessment times.
the beginning of
the intervention or
baseline assessment
(if the
intervention start
cannot be
determined) for all
outcomes except for
harms.
We will
extract harms
reported at any
followup,
regardless of the
duration since the
intervention start
or baseline
assessment.
Setting..................... KQ 1-3.............. In-patient, ED/EMS,
and psychiatric
Administered in subacute settings
outpatient health (e.g., partial
care or community hospitalization
settings (e.g., programs, intensive
schools, outpatient
residential). programs).
Trials
conducted in
countries rated as
``very high'' on
the 2019 Human
Development Index
(as defined by the
United Nations
Development
Program).
Study Design................ Randomized Other study designs.
controlled trials
(individually or
site-randomized),
with individually
randomized trials
reporting outcomes
for a minimum of 10
participants per
treatment arm.
Period 1
data from crossover
RCTs.
Published
in English-language.
Published
in 2010 or later.
------------------------------------------------------------------------
Abbreviations: AAQ = Acceptance and Action Questionnaire; AFQ-Y =
Avoidance and Fusion Questionnaire for Youth; BDI = Beck Depression
Inventory; BRIEF = Behavior Rating Inventory of Executive Function;
CAIS = Child Anxiety Impact Scale; CAMM = Child and Adolescent
Mindfulness Measure; CBCL = Child Behavior Checklist; CCSC =
Children's Coping Strategies Checklist; CDI = Children's Depression
Inventory; CDRS-R = Children's Depression Rating Scale-Revised; CES-D
= Center for Epidemiologic Studies Depression Scale; CGAS = Children's
Global Assessment Scale; CGI-I = Clinical Global Impression-
Improvement Scale; CHQ = Child Health Questionnaire; CSI-CA = Coping
Strategies Inventory for Children and Adolescents; ED/EMS = emergency
department/emergency medical services; ECBI = Eyberg Child Behavior
Inventory; FDI = Functional Disability Inventory Child Form; GAD-7 =
Generalized Anxiety Disorder scale; HRV = heart rate variability;
ITQOL = Infant/Toddler Quality of Life Questionnaire; KQ = Key
Question; MASC = Multidimensional Anxiety Scale for Children; MFQ =
Mood and Feelings Questionnaire; NA = not applicable; PedsQL =
Pediatric Quality of Life Inventory; PHQ-A = Patient Health
Questionnaire for Adolescents; PICOTS = population, interventions,
comparators, outcomes, timing, and setting; PI-ED = Paediatric Index
of Emotional Distress; PQ-LES-Q = Perceived Quality of Life Scale;
RADS = Reynolds Adolescent Depression Scale; RSQ = Responses to Stress
Questionnaire; SCARED = Screen for Child Anxiety Related Emotional
Disorders; SCAS = Spence Children's Anxiety Scale; SCL = Skin
Conductance Level; SDQ = Strengths and Difficulties Questionnaire;
SLSS = Students' Life Satisfaction Scale; SSIS = Social Skills
Improvement System; PANAS-C = Positive and Negative Affect Schedule
for Children; SWLS = Satisfaction with Life Scale; VABS = Vineland
Adaptive Behavior Scales; WIAT = Wechsler Individual Achievement Test;
WISC = Wechsler Intelligence Scale for Children.
\a\ These are reviewed in other AHRQ systematic reviews.
\b\ We defined behavioral interventions as nonpharmacologic strategies
intended to enhance outcomes by modifying behavior and/or ways of
thinking (e.g.,cognitive behavioral therapy, coping skills training,
behavioral therapy, biofeedback, dialectical behavioral therapy).
Dated: June 27, 2024.
Marquita Cullom,
Associate Director.
[FR Doc. 2024-14573 Filed 7-1-24; 8:45 am]
BILLING CODE 4160-90-P
