Interagency Coordinating Committee on the Validation of Alternative Methods Communities of Practice Webinar on Implementing Computational Approaches for Regulatory Safety Assessments; Notice of Public Webinar; Registration Information, 2963-2964 [2024-00758]

Download as PDF Federal Register / Vol. 89, No. 11 / Wednesday, January 17, 2024 / Notices guidelines may be formally referenced as ‘‘the poverty guidelines updated periodically in the Federal Register by the U.S. Department of Health and Human Services under the authority of 42 U.S.C. 9902(2).’’ Some federal programs use a percentage multiple of the guidelines (for example, 125 percent or 185 percent of the guidelines), as noted in relevant authorizing legislation or program regulations. Non-Federal organizations that use the poverty guidelines under their own authority in non-federallyfunded activities also may choose to use a percentage multiple of the guidelines. The poverty guidelines do not make a distinction between farm and non-farm families, or between aged and non-aged units. (Only the Census Bureau poverty thresholds have separate figures for aged and non-aged one-person and twoperson units.) 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[FR Doc. 2024–00796 Filed 1–16–24; 8:45 am] BILLING CODE 4150–05–P DEPARTMENT OF HEALTH AND HUMAN SERVICES lotter on DSK11XQN23PROD with NOTICES1 National Institutes of Health Interagency Coordinating Committee on the Validation of Alternative Methods Communities of Practice Webinar on Implementing Computational Approaches for Regulatory Safety Assessments; Notice of Public Webinar; Registration Information AGENCY: National Institutes of Health, HHS. ACTION: Notice. VerDate Sep<11>2014 18:14 Jan 16, 2024 Jkt 262001 The Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) announces the public webinar ‘‘Implementing Computational Approaches for Regulatory Safety Assessments.’’ The webinar is organized on behalf of ICCVAM by the National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM). Interested persons may participate via the web meeting platform. Time will be allotted for questions from the audience. Information about the webinar and registration are available at https:// ntp.niehs.nih.gov/go/commprac-2024. DATES: Webinar: January 29, 2024, 10 a.m. to approximately 12 noon EST. Registration for Webinar: January 10, 2024, until 12:00 noon EST January 29, 2024. Registration to view the webinar is required. ADDRESSES: Webinar web page: https:// ntp.niehs.nih.gov/go/commprac-2024. FOR FURTHER INFORMATION CONTACT: Dr. Helena Hogberg, Staff Scientist, NICEATM, email: helena.hogbergdurdock@nih.gov, telephone: (984) 287– 3150. SUPPLEMENTARY INFORMATION: Background: ICCVAM promotes the development and validation of toxicity testing methods that protect human health and the environment while replacing, reducing, or refining animal use. ICCVAM also provides guidance to test method developers and facilitates collaborations that promote the development of new test methods. To address these goals, ICCVAM will hold a Communities of Practice webinar on ‘‘Implementing Computational Approaches for Regulatory Safety Assessments.’’ Computational toxicology methods can be useful for generating bioactivity predictions for chemicals for which limited toxicity data are available. They can also help users understand and interpret large, diverse bioactivity data sets, or predict how a chemical might behave in the body. However, users with limited experience with such methods may find it difficult to use them or interpret their outputs, or even understand how the methods could be applied in a specific context. This webinar will discuss how to establish confidence in computational approaches for regulatory applications. Ongoing activities and key insights will be described in three presentations by speakers from the U.S. government and the private sector focusing on applications of tools such as structurebased models to predict chemical SUMMARY: PO 00000 Frm 00046 Fmt 4703 Sfmt 4703 2963 bioactivity and pharmacokinetic models to support understanding of chemical metabolism and disposition. The preliminary agenda and additional information about presentations will be posted at https://ntp.niehs.nih.gov/go/ commprac-2024 as they become available. Webinar and Registration: This webinar is open to the public with time scheduled for questions by participants following each presentation. Registration for the webinar is required. Registration will open on or before January 10, 2024, and remain open through 12 noon EST on January 29, 2024. Registration is available at https:// ntp.niehs.nih.gov/go/commprac-2024. Interested individuals are encouraged to visit this web page to stay abreast of the most current webinar information. Registrants will receive instructions on how to access and participate in the webinar in the email confirming their registration. TTY users should contact the Federal TTY Relay Service at 800– 877–8339. Requests should be made at least five business days in advance of the event. Background Information on ICCVAM and NICEATM: ICCVAM is an interagency committee composed of representatives from 17 Federal regulatory and research agencies that require, use, generate, or disseminate toxicological and safety testing information. ICCVAM conducts technical evaluations of new, revised, and alternative safety testing methods and integrated testing strategies with regulatory applicability. ICCVAM also promotes the scientific validation and regulatory acceptance of testing methods that more accurately assess the safety and hazards of chemicals and products and replace, reduce, or refine animal use. The ICCVAM Authorization Act of 2000 (42 U.S.C. 285l–3) establishes ICCVAM as a permanent interagency committee of the National Institute of Environmental Health Sciences and provides the authority for ICCVAM involvement in activities relevant to the development of alternative test methods. Additional information about ICCVAM can be found at https:// ntp.niehs.nih.gov/go/iccvam. NICEATM administers ICCVAM, provides support for ICCVAM-related activities, and conducts and publishes analyses and evaluations of data from new, revised, and alternative testing approaches. NICEATM and ICCVAM work collaboratively to evaluate new and improved testing approaches applicable to the needs of U.S. Federal agencies. NICEATM and ICCVAM welcome the public nomination of new, E:\FR\FM\17JAN1.SGM 17JAN1 2964 Federal Register / Vol. 89, No. 11 / Wednesday, January 17, 2024 / Notices revised, and alternative test methods and strategies for validation studies and technical evaluations. Additional information about NICEATM can be found at https://ntp.niehs.nih.gov/go/ niceatm. Dated: January 10, 2024. Richard P. Woychik, Director, National Institute of Environmental Health Sciences and National Toxicology Program, National Institutes of Health. Dated: January 11, 2024. Lauren A. Fleck, Program Analyst, Office of Federal Advisory Committee Policy. [FR Doc. 2024–00794 Filed 1–16–24; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health [FR Doc. 2024–00758 Filed 1–16–24; 8:45 am] National Cancer Institute; Notice of Closed Meetings BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Neurological Disorders and Stroke; Notice of Closed Meeting lotter on DSK11XQN23PROD with NOTICES1 Pursuant to section 1009 of the Federal Advisory Committee Act, as amended, notice is hereby given of the following meeting. The meeting will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: National Institute of Neurological Disorders and Stroke Special Emphasis Panel; NINDS R35 Overflow Meeting. Date: January 19, 2024. Time: 11:00 a.m. to 1:00 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, Neuroscience Center, 6001 Executive Boulevard, Rockville, MD 20852. Contact Person: DeAnna Lynn Adkins, Ph.D., Scientific Review Officer, Scientific Review Branch, Division of Extramural Activities, NINDS/NIH NSC, 6001 Executive Blvd., Rockville, MD 20852, 301–496–9223, deanna.adkins@nih.gov. This notice is being published less than 15 days prior to the meeting due to the timing limitations imposed by the review and funding cycle. (Catalogue of Federal Domestic Assistance Program Nos. 93.853, Clinical Research Related to Neurological Disorders; 93.854, Biological Basis Research in the Neurosciences, National Institutes of Health, HHS.) VerDate Sep<11>2014 18:14 Jan 16, 2024 Jkt 262001 Pursuant to section 1009 of the Federal Advisory Committee Act, as amended, notice is hereby given of the following meetings. The meetings will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications/ contract proposals and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications/ contract proposals, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: National Cancer Institute Special Emphasis Panel TEP–8: SBIR Contract Review. Date: February 14, 2024. Time: 11:00 a.m. to 5:00 p.m. Agenda: To review and evaluate contract proposals. Place: National Cancer Institute, Shady Grove, 9609 Medical Center Drive, Room 7W254, Rockville, Maryland 20850 (Virtual Meeting). Contact Person: Susan Lynn Spence, Ph.D., Scientific Review Officer, Research Technology and Contract Review Branch, Division of Extramural Activities, National Cancer Institute, NIH, 9609 Medical Center Drive, Room 7W254, Rockville, Maryland 20850, 240–620–0819, susan.spence@ nih.gov. Name of Committee: National Cancer Institute Special Emphasis Panel; TEP–6A: SBIR Contract Review. Date: February 22–23, 2024. Time: 10:00 a.m. to 5:00 p.m. Agenda: To review and evaluate contract proposals. Place: National Cancer Institute Shady Grove, 9609 Medical Center Drive, Room 7W254, Rockville, Maryland 20850 (Virtual Meeting). Contact Person: Susan Lynn Spence, Ph.D., Scientific Review Officer, Research Technology and Contract Review Branch, Division of Extramural Activities, National Cancer Institute, NIH, 9609 Medical Center Drive, Room 7W254, Rockville, Maryland 20850, 240–620–0819, susan.spence@ nih.gov. PO 00000 Frm 00047 Fmt 4703 Sfmt 4703 Name of Committee: National Cancer Institute Special Emphasis Panel; Human Tumor Atlas (HTA) Research Centers (U01). Date: February 29, 2024. Time: 9:00 a.m. to 6:00 p.m. Agenda: To review and evaluate grant applications. Place: National Cancer Institute at Shady Grove, 9609 Medical Center Drive, Room 7W240, Rockville, Maryland 20850 (Virtual Meeting). Contact Person: Hasan Siddiqui, Ph.D., Scientific Review Officer, Special Review Branch, Division of Extramural Activities, National Cancer Institute, NIH, 9609 Medical Center Drive, Room 7W240, Rockville, Maryland 20850, 240–276–5122, hasan.siddiqui@nih.gov. Name of Committee: National Cancer Institute Special Emphasis Panel; TEP–6B: SBIR Contract Review. Date: March 1, 2024. Time: 11:00 a.m. to 5:00 p.m. Agenda: To review and evaluate contract proposals. Place: National Cancer Institute Shady Grove, 9609 Medical Center Drive, Room 7W254, Rockville, Maryland 20850 (Virtual Meeting). Contact Person: Susan Lynn Spence, Ph.D., Scientific Review Officer, Research Technology and Contract Review Branch, Division of Extramural Activities, National Cancer Institute, NIH, 9609 Medical Center Drive, Room 7W254, Rockville, Maryland 20850, 240–620–0819, susan.spence@ nih.gov. Name of Committee: National Cancer Institute Special Emphasis Panel; SEP 11: NCI Clinical and Translational Cancer Research. Date: March 7, 2024. Time: 11:00 a.m. to 3:00 p.m. Agenda: To review and evaluate grant applications. Place: National Cancer Institute at Shady Grove, 9609 Medical Center Drive, Room 7W602, Rockville, Maryland 20850 (Virtual Meeting). Contact Person: Delia Tang, M.D., Scientific Review Officer, Resources and Training Review Branch, Division of Extramural Activities, National Cancer Institute, NIH, 9609 Medical Center Drive, Room 7W602, Rockville, Maryland 20850, 240–276–6456, tangd@mail.nih.gov. Name of Committee: National Cancer Institute Special Emphasis Panel; Translational Research Toward Development of a Kaposi Sarcoma Herpesvirus (KSHV) Vaccine (U01). Date: March 12, 2024. Time: 10:00 a.m. to 5:00 p.m. Agenda: To review and evaluate grant applications. Place: National Cancer Institute at Shady Grove, 9609 Medical Center Drive, Room 7W264, Rockville, Maryland 20850 (Virtual Meeting). Contact Person: Ombretta Salvucci, Ph.D., Scientific Review Officer, Special Review Branch, Division of Extramural Activities, National Cancer Institute, NIH, 9609 Medical Center Drive, Room 7W264, Rockville, Maryland 20850, 240–276–7286, salvucco@ mail.nih.gov. E:\FR\FM\17JAN1.SGM 17JAN1

Agencies

[Federal Register Volume 89, Number 11 (Wednesday, January 17, 2024)]
[Notices]
[Pages 2963-2964]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2024-00758]


-----------------------------------------------------------------------

DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Interagency Coordinating Committee on the Validation of 
Alternative Methods Communities of Practice Webinar on Implementing 
Computational Approaches for Regulatory Safety Assessments; Notice of 
Public Webinar; Registration Information

AGENCY: National Institutes of Health, HHS.

ACTION: Notice.

-----------------------------------------------------------------------

SUMMARY: The Interagency Coordinating Committee on the Validation of 
Alternative Methods (ICCVAM) announces the public webinar 
``Implementing Computational Approaches for Regulatory Safety 
Assessments.'' The webinar is organized on behalf of ICCVAM by the 
National Toxicology Program Interagency Center for the Evaluation of 
Alternative Toxicological Methods (NICEATM). Interested persons may 
participate via the web meeting platform. Time will be allotted for 
questions from the audience. Information about the webinar and 
registration are available at https://ntp.niehs.nih.gov/go/commprac-2024.

DATES: 
    Webinar: January 29, 2024, 10 a.m. to approximately 12 noon EST.
    Registration for Webinar: January 10, 2024, until 12:00 noon EST 
January 29, 2024. Registration to view the webinar is required.

ADDRESSES: Webinar web page: https://ntp.niehs.nih.gov/go/commprac-2024.

FOR FURTHER INFORMATION CONTACT: Dr. Helena Hogberg, Staff Scientist, 
NICEATM, email: [email protected], telephone: (984) 287-
3150.

SUPPLEMENTARY INFORMATION: 
    Background: ICCVAM promotes the development and validation of 
toxicity testing methods that protect human health and the environment 
while replacing, reducing, or refining animal use. ICCVAM also provides 
guidance to test method developers and facilitates collaborations that 
promote the development of new test methods. To address these goals, 
ICCVAM will hold a Communities of Practice webinar on ``Implementing 
Computational Approaches for Regulatory Safety Assessments.''
    Computational toxicology methods can be useful for generating 
bioactivity predictions for chemicals for which limited toxicity data 
are available. They can also help users understand and interpret large, 
diverse bioactivity data sets, or predict how a chemical might behave 
in the body. However, users with limited experience with such methods 
may find it difficult to use them or interpret their outputs, or even 
understand how the methods could be applied in a specific context.
    This webinar will discuss how to establish confidence in 
computational approaches for regulatory applications. Ongoing 
activities and key insights will be described in three presentations by 
speakers from the U.S. government and the private sector focusing on 
applications of tools such as structure-based models to predict 
chemical bioactivity and pharmacokinetic models to support 
understanding of chemical metabolism and disposition. The preliminary 
agenda and additional information about presentations will be posted at 
https://ntp.niehs.nih.gov/go/commprac-2024 as they become available.
    Webinar and Registration: This webinar is open to the public with 
time scheduled for questions by participants following each 
presentation. Registration for the webinar is required. Registration 
will open on or before January 10, 2024, and remain open through 12 
noon EST on January 29, 2024. Registration is available at https://ntp.niehs.nih.gov/go/commprac-2024. Interested individuals are 
encouraged to visit this web page to stay abreast of the most current 
webinar information. Registrants will receive instructions on how to 
access and participate in the webinar in the email confirming their 
registration. TTY users should contact the Federal TTY Relay Service at 
800-877-8339. Requests should be made at least five business days in 
advance of the event.
    Background Information on ICCVAM and NICEATM: ICCVAM is an 
interagency committee composed of representatives from 17 Federal 
regulatory and research agencies that require, use, generate, or 
disseminate toxicological and safety testing information. ICCVAM 
conducts technical evaluations of new, revised, and alternative safety 
testing methods and integrated testing strategies with regulatory 
applicability. ICCVAM also promotes the scientific validation and 
regulatory acceptance of testing methods that more accurately assess 
the safety and hazards of chemicals and products and replace, reduce, 
or refine animal use.
    The ICCVAM Authorization Act of 2000 (42 U.S.C. 285l-3) establishes 
ICCVAM as a permanent interagency committee of the National Institute 
of Environmental Health Sciences and provides the authority for ICCVAM 
involvement in activities relevant to the development of alternative 
test methods. Additional information about ICCVAM can be found at 
https://ntp.niehs.nih.gov/go/iccvam.
    NICEATM administers ICCVAM, provides support for ICCVAM-related 
activities, and conducts and publishes analyses and evaluations of data 
from new, revised, and alternative testing approaches. NICEATM and 
ICCVAM work collaboratively to evaluate new and improved testing 
approaches applicable to the needs of U.S. Federal agencies. NICEATM 
and ICCVAM welcome the public nomination of new,

[[Page 2964]]

revised, and alternative test methods and strategies for validation 
studies and technical evaluations. Additional information about NICEATM 
can be found at https://ntp.niehs.nih.gov/go/niceatm.

    Dated: January 10, 2024.
Richard P. Woychik,
Director, National Institute of Environmental Health Sciences and 
National Toxicology Program, National Institutes of Health.
[FR Doc. 2024-00758 Filed 1-16-24; 8:45 am]
BILLING CODE 4140-01-P

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