Diabetic Foot Infections: Developing Drugs for Treatment; Draft Guidance for Industry; Availability, 71578-71580 [2023-22842]
Download as PDF
71578
Federal Register / Vol. 88, No. 199 / Tuesday, October 17, 2023 / Notices
Dated: October 11, 2023.
Lauren K. Roth,
Associate Commissioner for Policy.
[FR Doc. 2023–22843 Filed 10–16–23; 8:45 am]
BILLING CODE 4164–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA–2023–P–3682]
Determination That ZOFRAN ODT
(Ondansetron) Orally Disintegrating
Tablets, 4 Milligrams and 8 Milligrams,
Were Not Withdrawn From Sale for
Reasons of Safety or Effectiveness
AGENCY:
Food and Drug Administration,
HHS.
ACTION:
Notice.
The Food and Drug
Administration (FDA or the Agency) has
determined that ZOFRAN ODT
(ondansetron) orally disintegrating
tablets, 4 milligrams (mg) and 8 mg,
were not withdrawn from sale for
reasons of safety or effectiveness. This
determination means that FDA will not
begin procedures to withdraw approval
of abbreviated new drug applications
(ANDAs) that refer to these drug
products, and it will allow FDA to
continue to approve ANDAs that refer to
the products as long as they meet
relevant legal and regulatory
requirements.
SUMMARY:
FOR FURTHER INFORMATION CONTACT:
Veniqua Stewart, Center for Drug
Evaluation and Research, Food and
Drug Administration, 10903 New
Hampshire Ave., Bldg. 51, Rm. 6219,
Silver Spring, MD 20993–0002, 301–
796–3267, Veniqua.stewart@
fda.hhs.gov.
Section
505(j) of the Federal Food, Drug, and
Cosmetic Act (FD&C Act) (21 U.S.C.
355(j)) allows the submission of an
ANDA to market a generic version of a
previously approved drug product. To
obtain approval, the ANDA applicant
must show, among other things, that the
generic drug product: (1) has the same
active ingredient(s), dosage form, route
of administration, strength, conditions
of use, and (with certain exceptions)
labeling as the listed drug, which is a
version of the drug that was previously
approved, and (2) is bioequivalent to the
listed drug. ANDA applicants do not
have to repeat the extensive clinical
testing otherwise necessary to gain
approval of a new drug application
(NDA).
lotter on DSK11XQN23PROD with NOTICES1
SUPPLEMENTARY INFORMATION:
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Jkt 262001
Section 505(j)(7) of the FD&C Act
requires FDA to publish a list of all
approved drugs. FDA publishes this list
as part of the ‘‘Approved Drug Products
With Therapeutic Equivalence
Evaluations,’’ which is known generally
as the ‘‘Orange Book.’’ Under FDA
regulations, drugs are removed from the
list if the Agency withdraws or
suspends approval of the drug’s NDA or
ANDA for reasons of safety or
effectiveness or if FDA determines that
the listed drug was withdrawn from sale
for reasons of safety or effectiveness (21
CFR 314.162).
A person may petition the Agency to
determine, or the Agency may
determine on its own initiative, whether
a listed drug was withdrawn from sale
for reasons of safety or effectiveness.
This determination may be made at any
time after the drug has been withdrawn
from sale, but must be made prior to
approving an ANDA that refers to the
listed drug (§ 314.161 (21 CFR 314.161)).
FDA may not approve an ANDA that
does not refer to a listed drug.
ZOFRAN ODT (ondansetron) orally
disintegrating tablets, 4 mg and 8 mg,
are the subject of NDA 020781, held by
Sandoz Inc., and initially approved on
January 27, 1999. ZOFRAN ODT is
indicated for the prevention of nausea
and vomiting associated with: highly
emetogenic cancer chemotherapy,
including cisplatin greater than or equal
to 50 mg/m2; initial and repeat courses
of moderately emetogenic cancer
chemotherapy; and radiotherapy in
patients receiving either total body
irradiation, single high-dose fraction to
the abdomen, or daily fractions to the
abdomen. ZOFRAN ODT is also
indicated for the prevention of
postoperative nausea and/or vomiting.
ZOFRAN ODT (ondansetron) orally
disintegrating tablets, 4 mg and 8 mg,
are currently listed in the ‘‘Discontinued
Drug Product List’’ section of the Orange
Book.
Sun Pharmaceutical Industries
Limited submitted a citizen petition
dated August 24, 2023 (Docket No.
FDA–2023–P–3682), under 21 CFR
10.30, requesting that the Agency
determine whether ZOFRAN ODT
(ondansetron) orally disintegrating
tablets, 4 mg and 8 mg, were withdrawn
from sale for reasons of safety or
effectiveness.
After considering the citizen petition
and reviewing Agency records and
based on the information we have at this
time, FDA has determined under
§ 314.161 that ZOFRAN ODT
(ondansetron) orally disintegrating
tablets, 4 mg and 8 mg, were not
withdrawn from sale for reasons of
safety or effectiveness. The petitioner
PO 00000
Frm 00052
Fmt 4703
Sfmt 4703
has identified no data or other
information suggesting that ZOFRAN
ODT (ondansetron) orally disintegrating
tablets, 4 mg and 8 mg, were withdrawn
for reasons of safety or effectiveness. We
have carefully reviewed our files for
records concerning the withdrawal of
ZOFRAN ODT (ondansetron) orally
disintegrating tablets, 4 mg and 8 mg,
from sale. We have also independently
evaluated relevant literature and data
for possible postmarketing adverse
events. We have reviewed the available
evidence and determined that these
drug products were not withdrawn from
sale for reasons of safety or
effectiveness.
Accordingly, the Agency will
continue to list ZOFRAN ODT
(ondansetron) orally disintegrating
tablets, 4 mg and 8 mg, in the
‘‘Discontinued Drug Product List’’
section of the Orange Book. The
‘‘Discontinued Drug Product List’’
delineates, among other items, drug
products that have been discontinued
from marketing for reasons other than
safety or effectiveness. FDA will not
begin procedures to withdraw approval
of approved ANDAs that refer to these
drug products. Additional ANDAs for
these drug products may also be
approved by the Agency as long as they
meet all other legal and regulatory
requirements for the approval of
ANDAs. If FDA determines that labeling
for these drug products should be
revised to meet current standards, the
Agency will advise ANDA applicants to
submit such labeling.
Dated: October 10, 2023.
Lauren K. Roth,
Associate Commissioner for Policy.
[FR Doc. 2023–22844 Filed 10–16–23; 8:45 am]
BILLING CODE 4164–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA–2023–D–4067]
Diabetic Foot Infections: Developing
Drugs for Treatment; Draft Guidance
for Industry; Availability
AGENCY:
Food and Drug Administration,
HHS.
ACTION:
Notice of availability.
The Food and Drug
Administration (FDA or Agency) is
announcing the availability of a draft
guidance for industry entitled ‘‘Diabetic
Foot Infections: Developing Drugs for
Treatment.’’ The purpose of this draft
guidance is to assist sponsors in the
SUMMARY:
E:\FR\FM\17OCN1.SGM
17OCN1
Federal Register / Vol. 88, No. 199 / Tuesday, October 17, 2023 / Notices
clinical development of drugs for the
treatment of diabetic foot infections
(DFI) without concomitant bone and
joint involvement.
DATES: Submit either electronic or
written comments on the draft guidance
by December 18, 2023 to ensure that the
Agency considers your comment on this
draft guidance before it begins work on
the final version of the guidance.
ADDRESSES: You may submit comments
on any guidance at any time as follows:
Electronic Submissions
Submit electronic comments in the
following way:
• Federal eRulemaking Portal:
https://www.regulations.gov. Follow the
instructions for submitting comments.
Comments submitted electronically,
including attachments, to https://
www.regulations.gov will be posted to
the docket unchanged. Because your
comment will be made public, you are
solely responsible for ensuring that your
comment does not include any
confidential information that you or a
third party may not wish to be posted,
such as medical information, your or
anyone else’s Social Security number, or
confidential business information, such
as a manufacturing process. Please note
that if you include your name, contact
information, or other information that
identifies you in the body of your
comments, that information will be
posted on https://www.regulations.gov.
• If you want to submit a comment
with confidential information that you
do not wish to be made available to the
public, submit the comment as a
written/paper submission and in the
manner detailed (see ‘‘Written/Paper
Submissions’’ and ‘‘Instructions’’).
lotter on DSK11XQN23PROD with NOTICES1
Written/Paper Submissions
Submit written/paper submissions as
follows:
• Mail/Hand Delivery/Courier (for
written/paper submissions): Dockets
Management Staff (HFA–305), Food and
Drug Administration, 5630 Fishers
Lane, Rm. 1061, Rockville, MD 20852.
• For written/paper comments
submitted to the Dockets Management
Staff, FDA will post your comment, as
well as any attachments, except for
information submitted, marked, and
identified, as confidential, if submitted
as detailed in ‘‘Instructions.’’
Instructions: All submissions received
must include the Docket No. FDA–
2023–D–4067 for ‘‘Diabetic Foot
Infections: Developing Drugs for
Treatment.’’ Received comments will be
placed in the docket and, except for
those submitted as ‘‘Confidential
Submissions,’’ publicly viewable at
VerDate Sep<11>2014
17:02 Oct 16, 2023
Jkt 262001
https://www.regulations.gov or at the
Dockets Management Staff between 9
a.m. and 4 p.m., Monday through
Friday, 240–402–7500.
• Confidential Submissions—To
submit a comment with confidential
information that you do not wish to be
made publicly available, submit your
comments only as a written/paper
submission. You should submit two
copies total. One copy will include the
information you claim to be confidential
with a heading or cover note that states
‘‘THIS DOCUMENT CONTAINS
CONFIDENTIAL INFORMATION.’’ The
Agency will review this copy, including
the claimed confidential information, in
its consideration of comments. The
second copy, which will have the
claimed confidential information
redacted/blacked out, will be available
for public viewing and posted on
https://www.regulations.gov. Submit
both copies to the Dockets Management
Staff. If you do not wish your name and
contact information to be made publicly
available, you can provide this
information on the cover sheet and not
in the body of your comments and you
must identify this information as
‘‘confidential.’’ Any information marked
as ‘‘confidential’’ will not be disclosed
except in accordance with 21 CFR 10.20
and other applicable disclosure law. For
more information about FDA’s posting
of comments to public dockets, see 80
FR 56469, September 18, 2015, or access
the information at: https://
www.govinfo.gov/content/pkg/FR-201509-18/pdf/2015-23389.pdf.
Docket: For access to the docket to
read background documents or the
electronic and written/paper comments
received, go to https://
www.regulations.gov and insert the
docket number, found in brackets in the
heading of this document, into the
‘‘Search’’ box and follow the prompts
and/or go to the Dockets Management
Staff, 5630 Fishers Lane, Rm. 1061,
Rockville, MD 20852, 240–402–7500.
You may submit comments on any
guidance at any time (see 21 CFR
10.115(g)(5)).
Submit written requests for single
copies of the draft guidance to the
Division of Drug Information, Center for
Drug Evaluation and Research, Food
and Drug Administration, 10001 New
Hampshire Ave., Hillandale Building,
4th Floor, Silver Spring, MD 20993–
0002. Send one self-addressed adhesive
label to assist that office in processing
your requests. See the SUPPLEMENTARY
INFORMATION section for electronic
access to the draft guidance document.
FOR FURTHER INFORMATION CONTACT:
Mayurika Ghosh, Center for Drug
PO 00000
Frm 00053
Fmt 4703
Sfmt 4703
71579
Evaluation and Research, Food and
Drug Administration, 10903 New
Hampshire Ave., Bldg. 22, Rm. 6219,
Silver Spring, MD 20993, 301–796–
4776.
SUPPLEMENTARY INFORMATION:
I. Background
FDA is announcing the availability of
a draft guidance for industry entitled
‘‘Diabetic Foot Infections: Developing
Drugs for Treatment.’’
The purpose of this draft guidance is
to assist sponsors in the clinical
development of drugs for the treatment
of DFI without concomitant bone and
joint involvement. Specifically, this
guidance addresses FDA’s current
thinking regarding the overall
development program and clinical trial
designs for the development of drugs to
support an indication for treatment of
DFI.
This draft guidance is being issued
consistent with FDA’s good guidance
practices regulation (21 CFR 10.115).
The draft guidance, when finalized, will
represent the current thinking of FDA
on ‘‘Diabetic Foot Infections:
Developing Drugs for Treatment.’’ It
does not establish any rights for any
person and is not binding on FDA or the
public. You can use an alternative
approach if it satisfies the requirements
of the applicable statutes and
regulations.
II. Paperwork Reduction Act of 1995
While this guidance contains no
collection of information, it does refer to
previously approved FDA collections of
information. The previously approved
collections of information are subject to
review by the Office of Management and
Budget (OMB) under the Paperwork
Reduction Act of 1995 (PRA) (44 U.S.C.
3501–3521). The collections of
information in 21 CFR part 314 have
been approved under OMB control
number 0910–0001. The collections of
information in 21 CFR part 312 have
been approved under OMB control
number 0910–0014. The collections of
information in 21 CFR 201.56 and
201.57 relating to prescription product
labeling requirements have been
approved under OMB control number
0910–0572.
III. Electronic Access
Persons with access to the internet
may obtain the draft guidance at https://
www.fda.gov/drugs/guidancecompliance-regulatory-information/
guidances-drugs, https://www.fda.gov/
regulatory-information/search-fdaguidance-documents, or https://
www.regulations.gov.
E:\FR\FM\17OCN1.SGM
17OCN1
71580
Federal Register / Vol. 88, No. 199 / Tuesday, October 17, 2023 / Notices
Dated: October 11, 2023.
Lauren K. Roth,
Associate Commissioner for Policy.
Intended Recipient of the Award: The
University of Kentucky.
Amount of Non-Competitive Award:
One award for $250,000.
Project Period: September 1, 2023, to
August 31, 2024.
CFDA Number: 93.155.
Award Instrument: Supplement.
Authority: Social Security Act section
711(b) (42 U.S.C. 912(b)).
Announcing funding
supplement for Rural Health and
Economic Development Analysis
Program.
ACTION:
[FR Doc. 2023–22842 Filed 10–16–23; 8:45 am]
BILLING CODE 4164–01–P
HRSA provided additional
award funds to the Rural Health and
Economic Development Analysis
Program recipient to produce a research
project that quantifies the relationships
between health care and economic
factors in rural communities.
SUMMARY:
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Health Resources and Services
Administration
FOR FURTHER INFORMATION CONTACT:
Rural Health and Economic
Development Analysis Program
Health Resources and Services
Administration (HRSA), Department of
Health and Human Services.
AGENCY:
Karis Tyner, Federal Office of Rural
Health Policy, HRSA, at ktyner@
hrsa.gov and (240) 645–5756.
SUPPLEMENTARY INFORMATION:
TABLE 1—RECIPIENT AND AWARD AMOUNT
Grant No.
Award recipient name
City, state
5 U1ZRH33331 .......................
The University of Kentucky ......................................................
Lexington, KY .........................
Justification: This funding will
provide a one-time supplement to the
University of Kentucky via the Rural
Health and Economic Development
Analysis Program with a budget period
of September 2023 through August
2024. This supplement will allow the
University of Kentucky to build on past
and ongoing projects supported by
HRSA to improve health care in rural
areas by advancing the knowledge base
regarding the economic impacts of local
health care sectors on rural economies.
Carole Johnson,
Administrator.
[FR Doc. 2023–22814 Filed 10–16–23; 8:45 am]
BILLING CODE 4165–15–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Announcement of Solicitation of
Written Comments on Healthy People
2030 Objectives
Office of Disease Prevention
and Health Promotion, Office of the
Assistant Secretary of Health, Office of
the Secretary, Department of Health and
Human Services.
ACTION: Notice.
AGENCY:
The U.S. Department of
Health and Human Services (HHS)
solicits written comments from the
public on the current Healthy People
2030 objectives, and written comments
from the public proposing additional
new core, developmental, or research
objectives or topics to be included in
Healthy People 2030. Public comment
lotter on DSK11XQN23PROD with NOTICES1
SUMMARY:
VerDate Sep<11>2014
17:02 Oct 16, 2023
Jkt 262001
informed the development of Healthy
People 2030. HHS will provide
opportunities for public input
periodically throughout the decade to
ensure Healthy People 2030 reflects
current public health priorities and
public input. The updated set of
Healthy People 2030 objectives and
topics will be incorporated on https://
health.gov/healthypeople. This updated
set will reflect further review and
deliberation by Federal Healthy People
topic area workgroups, the Federal
Interagency Workgroup on Healthy
People 2030, and other Federal subject
matter experts.
DATES: Written comments will be
accepted through 11:59 p.m. ET,
November 20, 2023.
ADDRESSES: Written comments should
be submitted by email to
HP2030Comment@hhs.gov.
FOR FURTHER INFORMATION CONTACT: Erik
Orta, Office of Disease Prevention and
Health Promotion, U.S. Department of
Health and Human Services, 1101
Wootton Parkway, Suite 420, Rockville,
MD 20852; Phone: 240–268–0823;
Email: HP2030@hhs.gov.
SUPPLEMENTARY INFORMATION: Since
1980, Healthy People has provided a
comprehensive set of national health
promotion and disease prevention
objectives with 10-year targets aimed at
improving the health of all. Healthy
People 2030 objectives present a picture
of the nation’s health at the beginning
of the decade, establish national goals
and targets to be achieved by the year
2030, and monitor progress over time.
The U.S. Department of Health and
PO 00000
Frm 00054
Fmt 4703
Sfmt 4703
Supplemental
award amount
$250,000
Human Services (HHS) is soliciting the
submission of written comments
regarding the current Healthy People
2030 objectives. The public is also
invited to submit proposals for
additional new core, developmental, or
research objectives that meet the criteria
outlined below.
Healthy People 2030 is the product of
an extensive collaborative process that
relies on input from a diverse array of
individuals and organizations, both
within and outside the Federal
Government, with a common interest in
improving the nation’s health. Public
comments were a cornerstone of
Healthy People 2030’s development.
During the first phase of planning for
Healthy People 2030, HHS asked for the
public’s comments on the initiative’s
vision, mission, and overarching goals.
Those comments helped set the
framework for Healthy People 2030. The
public was also invited to submit
comments on proposed Healthy People
2030 objectives, which helped shape the
current set of Healthy People 2030
objectives. HHS most recently solicited
comments on one new objective during
the 2022 public comment period from
October 24, 2022, through December 2,
2022, and three new proposed
objectives during the 2021 public
comment period from December 3,
2021, through January 10, 2022. These
new objectives, which were developed
by Healthy People 2030 subject matter
experts, meet specific criteria, and
reflect public input, are now accessible
on https://health.gov/healthypeople.
While there are no new objectives
being proposed at this time, the public
E:\FR\FM\17OCN1.SGM
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Agencies
[Federal Register Volume 88, Number 199 (Tuesday, October 17, 2023)]
[Notices]
[Pages 71578-71580]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2023-22842]
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA-2023-D-4067]
Diabetic Foot Infections: Developing Drugs for Treatment; Draft
Guidance for Industry; Availability
AGENCY: Food and Drug Administration, HHS.
ACTION: Notice of availability.
-----------------------------------------------------------------------
SUMMARY: The Food and Drug Administration (FDA or Agency) is announcing
the availability of a draft guidance for industry entitled ``Diabetic
Foot Infections: Developing Drugs for Treatment.'' The purpose of this
draft guidance is to assist sponsors in the
[[Page 71579]]
clinical development of drugs for the treatment of diabetic foot
infections (DFI) without concomitant bone and joint involvement.
DATES: Submit either electronic or written comments on the draft
guidance by December 18, 2023 to ensure that the Agency considers your
comment on this draft guidance before it begins work on the final
version of the guidance.
ADDRESSES: You may submit comments on any guidance at any time as
follows:
Electronic Submissions
Submit electronic comments in the following way:
Federal eRulemaking Portal: https://www.regulations.gov.
Follow the instructions for submitting comments. Comments submitted
electronically, including attachments, to https://www.regulations.gov
will be posted to the docket unchanged. Because your comment will be
made public, you are solely responsible for ensuring that your comment
does not include any confidential information that you or a third party
may not wish to be posted, such as medical information, your or anyone
else's Social Security number, or confidential business information,
such as a manufacturing process. Please note that if you include your
name, contact information, or other information that identifies you in
the body of your comments, that information will be posted on https://www.regulations.gov.
If you want to submit a comment with confidential
information that you do not wish to be made available to the public,
submit the comment as a written/paper submission and in the manner
detailed (see ``Written/Paper Submissions'' and ``Instructions'').
Written/Paper Submissions
Submit written/paper submissions as follows:
Mail/Hand Delivery/Courier (for written/paper
submissions): Dockets Management Staff (HFA-305), Food and Drug
Administration, 5630 Fishers Lane, Rm. 1061, Rockville, MD 20852.
For written/paper comments submitted to the Dockets
Management Staff, FDA will post your comment, as well as any
attachments, except for information submitted, marked, and identified,
as confidential, if submitted as detailed in ``Instructions.''
Instructions: All submissions received must include the Docket No.
FDA-2023-D-4067 for ``Diabetic Foot Infections: Developing Drugs for
Treatment.'' Received comments will be placed in the docket and, except
for those submitted as ``Confidential Submissions,'' publicly viewable
at https://www.regulations.gov or at the Dockets Management Staff
between 9 a.m. and 4 p.m., Monday through Friday, 240-402-7500.
Confidential Submissions--To submit a comment with
confidential information that you do not wish to be made publicly
available, submit your comments only as a written/paper submission. You
should submit two copies total. One copy will include the information
you claim to be confidential with a heading or cover note that states
``THIS DOCUMENT CONTAINS CONFIDENTIAL INFORMATION.'' The Agency will
review this copy, including the claimed confidential information, in
its consideration of comments. The second copy, which will have the
claimed confidential information redacted/blacked out, will be
available for public viewing and posted on https://www.regulations.gov.
Submit both copies to the Dockets Management Staff. If you do not wish
your name and contact information to be made publicly available, you
can provide this information on the cover sheet and not in the body of
your comments and you must identify this information as
``confidential.'' Any information marked as ``confidential'' will not
be disclosed except in accordance with 21 CFR 10.20 and other
applicable disclosure law. For more information about FDA's posting of
comments to public dockets, see 80 FR 56469, September 18, 2015, or
access the information at: https://www.govinfo.gov/content/pkg/FR-2015-09-18/pdf/2015-23389.pdf.
Docket: For access to the docket to read background documents or
the electronic and written/paper comments received, go to https://www.regulations.gov and insert the docket number, found in brackets in
the heading of this document, into the ``Search'' box and follow the
prompts and/or go to the Dockets Management Staff, 5630 Fishers Lane,
Rm. 1061, Rockville, MD 20852, 240-402-7500.
You may submit comments on any guidance at any time (see 21 CFR
10.115(g)(5)).
Submit written requests for single copies of the draft guidance to
the Division of Drug Information, Center for Drug Evaluation and
Research, Food and Drug Administration, 10001 New Hampshire Ave.,
Hillandale Building, 4th Floor, Silver Spring, MD 20993-0002. Send one
self-addressed adhesive label to assist that office in processing your
requests. See the SUPPLEMENTARY INFORMATION section for electronic
access to the draft guidance document.
FOR FURTHER INFORMATION CONTACT: Mayurika Ghosh, Center for Drug
Evaluation and Research, Food and Drug Administration, 10903 New
Hampshire Ave., Bldg. 22, Rm. 6219, Silver Spring, MD 20993, 301-796-
4776.
SUPPLEMENTARY INFORMATION:
I. Background
FDA is announcing the availability of a draft guidance for industry
entitled ``Diabetic Foot Infections: Developing Drugs for Treatment.''
The purpose of this draft guidance is to assist sponsors in the
clinical development of drugs for the treatment of DFI without
concomitant bone and joint involvement. Specifically, this guidance
addresses FDA's current thinking regarding the overall development
program and clinical trial designs for the development of drugs to
support an indication for treatment of DFI.
This draft guidance is being issued consistent with FDA's good
guidance practices regulation (21 CFR 10.115). The draft guidance, when
finalized, will represent the current thinking of FDA on ``Diabetic
Foot Infections: Developing Drugs for Treatment.'' It does not
establish any rights for any person and is not binding on FDA or the
public. You can use an alternative approach if it satisfies the
requirements of the applicable statutes and regulations.
II. Paperwork Reduction Act of 1995
While this guidance contains no collection of information, it does
refer to previously approved FDA collections of information. The
previously approved collections of information are subject to review by
the Office of Management and Budget (OMB) under the Paperwork Reduction
Act of 1995 (PRA) (44 U.S.C. 3501-3521). The collections of information
in 21 CFR part 314 have been approved under OMB control number 0910-
0001. The collections of information in 21 CFR part 312 have been
approved under OMB control number 0910-0014. The collections of
information in 21 CFR 201.56 and 201.57 relating to prescription
product labeling requirements have been approved under OMB control
number 0910-0572.
III. Electronic Access
Persons with access to the internet may obtain the draft guidance
at https://www.fda.gov/drugs/guidance-compliance-regulatory-information/guidances-drugs, https://www.fda.gov/regulatory-information/search-fda-guidance-documents, or https://www.regulations.gov.
[[Page 71580]]
Dated: October 11, 2023.
Lauren K. Roth,
Associate Commissioner for Policy.
[FR Doc. 2023-22842 Filed 10-16-23; 8:45 am]
BILLING CODE 4164-01-P