National Institute of Dental and Craniofacial Research; Amended Notice of Meeting, 60695 [2023-19017]
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Federal Register / Vol. 88, No. 170 / Tuesday, September 5, 2023 / Notices
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FOR FURTHER INFORMATION CONTACT:
Sheila Garrity, JD, MPH, MBA, Director,
Office of Research Integrity, 1101
Wootton Parkway, Suite 240, Rockville,
MD 20852, (240) 453–8200.
SUPPLEMENTARY INFORMATION: Notice is
hereby given that the Office of Research
Integrity (ORI) has taken final action in
the following case:
Ivana Frech, Ph.D. (formerly Ivana De
Domenico), University of Utah: Based
on the evidence and findings of an
investigation conducted by UU, ORI’s
oversight review of UU’s investigation,
and additional analysis conducted by
ORI during its oversight review, ORI
found that Ivana Frech, Ph.D. (formerly
Ivana De Domenico), former Assistant
Professor, Department of Internal
Medicine, UU School of Medicine,
engaged in research misconduct under
42 CFR part 93 in research supported by
PHS funds, specifically NIDDK, NIH,
grants R01 DK070947, R01 DK090257,
and R01 DK030534, NIGMS, NIH, grant
P50 GM082545, NIAID, NIH, grant R01
AI051174, and NHLBI, NIH, grant R01
HL026922.
ORI found by a preponderance of the
evidence that Respondent intentionally,
knowingly, or recklessly falsified and/or
fabricated western blot and
autoradiogram images related to
mechanisms of cellular iron regulation
by reusing, relabeling, and manipulating
images to falsely report data in eight (8)
figures included in the following three
(3) PHS-supported published papers:
• Two Distinct Modes of ESCRT–III
Recognition are Required for VPS4
Functions in Lysosomal Protein
Targeting and HIV–1 Budding. Dev Cell.
2008 Jul;15(1):62–73. doi: 10.1016/
j.devcel.2008.05.014 (hereafter referred
to as ‘‘Dev. Cell 2008’’).
• The Role of Ubiquitination in
Hepcidin-independent and Hepcidindependent Degradation of Ferroportin.
Cell Metab. 2011 Nov 2;14(5):635–46.
doi: 10.1016/j.cmet.2011.09.008
(hereafter referred to as ‘‘Cell Met. Nov.
2011’’) Retracted: Cell Met. 2012 Jun
6;15(6):927. doi: 10.1016/
j.cmet.2012.04.107.
• Decoupling Ferritin Synthesis from
Free Cytosolic Iron Results in Ferritin
Secretion. Cell Metab. 2011 Jan
5;13(1):57–67. doi: 10.1016/
j.cmet.2010.12.003 (hereafter referred to
as ‘‘Cell Met. Jan. 2011’’). Retracted: Cell
Met. 2012 Jun 6;15(6):927. doi: 10.1016/
j.cmet.2012.04.012.
ORI found that these acts constitute a
significant departure from accepted
practices of the relevant research
community. Specifically, ORI found by
a preponderance of the evidence that
Respondent engaged in research
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60695
misconduct by intentionally,
knowingly, or recklessly falsifying and/
or fabricating:
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
• a western blot image in Figure 5B
(right bottom panel) of Dev. Cell 2008
by reusing and relabeling an image of
three western blot bands to represent
the results of different experiments
• western blot images in Figure 1C (top
and bottom panels) of Cell Met. Nov.
2011 by reusing and relabeling an
image of western blot bands to
represent the results of two different
experiments
• western blot images in Figures 1D and
3 of Cell Met. Nov. 2011 by reusing
and relabeling one image to represent
the results of two different
experiments
• western blot images in Figures 2Aii
and 2B of Cell Met. Nov. 2011 by
reusing and relabeling one image as
representing the results of two
different experiments
• western blot images in Figures 2Aii
and 5 of Cell Met. Nov. 2011 by
reusing and relabeling one image as
representing the results of two
different experiments
• images in Figure 4B (top and bottom
left panels) of Cell Met. Jan. 2011 by
reusing and relabeling an image of an
autoradiogram to misrepresent the
reported experimental conditions and
results
National Institutes of Health
The following administrative actions
have been implemented:
(1) For a period of three (3) years,
beginning on August 21, 2023,
Respondent is debarred from
participating in ‘‘covered transactions’’
as defined in 42 CFR 180.200 and
procurement transactions covered under
the Federal Acquisition Regulation (48
CFR chapter 1).
(2) Respondent is prohibited from
serving in any advisory capacity to PHS
including, but not limited to, service on
any PHS advisory committee, board,
and/or peer review committee, or as a
consultant for a period of three (3) years,
beginning on August 21, 2023.
(3) In accordance with 42 CFR
93.407(a)(1) and 93.411(b), HHS will
send to the journal Developmental Cell
a notice of ORI’s findings and the need
for retraction or correction of Dev Cell.
2008 Jul;15(1):62–73. doi: 10.1016/
j.devcel.2008.05.014.
Dated: August 30, 2023.
Sheila Garrity,
Director, Office of Research Integrity, Office
of the Assistant Secretary for Health.
[FR Doc. 2023–19086 Filed 9–1–23; 8:45 am]
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National Institute of Dental and
Craniofacial Research; Amended
Notice of Meeting
Notice is hereby given of a change in
the meeting of the National Advisory
Dental and Craniofacial Research
Council, September 12, 2023, 4:45 p.m.
to September 13, 2023, 3:30 p.m.,
National Institutes of Health, Natcher
Building, 45 Center Drive, Bethesda, MD
20892, which was published in the
Federal Register on August 17, 2023, FR
Document 2023–17712, 88 FR 56028.
The National Advisory Dental and
Craniofacial Research Council Open and
Closed Sessions meeting room has
changed from the Natcher Building, 45
Center Drive, Bethesda, MD 20892, and
will now be held at the John Edward
Porter Neuroscience Research Center
Building, 35 Convent Drive Room 620/
630, Bethesda, MD 20892. Meeting
times remain the same. The meeting is
partially closed to the public.
Dated: August 29, 2023.
Melanie J. Pantoja,
Program Analyst, Office of Federal Advisory
Committee Policy.
[FR Doc. 2023–19017 Filed 9–1–23; 8:45 am]
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DEPARTMENT OF HOMELAND
SECURITY
[Docket Number DHS–2023–0020]
Agency Information Collection
Activities: Generic Clearance for
Improving Customer Experience (OMB
Circular A–11, Section 280
Implementation), 1601–0029
Department of Homeland
Security (DHS).
ACTION: 30-Day notice and request for
comments.
AGENCY:
The Department of Homeland
Security, DHS will submit the following
information collection request (ICR) to
the Office of Management and Budget
(OMB) for review and clearance in
accordance with the Paperwork
Reduction Act. DHS previously
published this information collection
request (ICR) in the Federal Register on
June 23, 2023, for a 60-day public
comment period. No comments were
received by DHS. The purpose of this
notice is to allow additional 30-days for
public comments.
DATES: Comments are encouraged and
will be accepted until October 5, 2023.
SUMMARY:
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Agencies
[Federal Register Volume 88, Number 170 (Tuesday, September 5, 2023)]
[Notices]
[Page 60695]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2023-19017]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health
National Institute of Dental and Craniofacial Research; Amended
Notice of Meeting
Notice is hereby given of a change in the meeting of the National
Advisory Dental and Craniofacial Research Council, September 12, 2023,
4:45 p.m. to September 13, 2023, 3:30 p.m., National Institutes of
Health, Natcher Building, 45 Center Drive, Bethesda, MD 20892, which
was published in the Federal Register on August 17, 2023, FR Document
2023-17712, 88 FR 56028.
The National Advisory Dental and Craniofacial Research Council Open
and Closed Sessions meeting room has changed from the Natcher Building,
45 Center Drive, Bethesda, MD 20892, and will now be held at the John
Edward Porter Neuroscience Research Center Building, 35 Convent Drive
Room 620/630, Bethesda, MD 20892. Meeting times remain the same. The
meeting is partially closed to the public.
Dated: August 29, 2023.
Melanie J. Pantoja,
Program Analyst, Office of Federal Advisory Committee Policy.
[FR Doc. 2023-19017 Filed 9-1-23; 8:45 am]
BILLING CODE 4140-01-P