Request for Public Comment on Two Draft Immediately Dangerous to Life or Health (IDLH) Values, for Hydrogen Bromide and Hydrogen Iodide, 40826-40827 [2023-13251]
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Federal Register / Vol. 88, No. 119 / Thursday, June 22, 2023 / Notices
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[FR Doc. 2023–13288 Filed 6–21–23; 8:45 am]
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Centers for Disease Control and
Prevention
[Docket Number CDC–2019–0093, NIOSH–
156–E]
ddrumheller on DSK120RN23PROD with NOTICES1
Request for Public Comment on Two
Draft Immediately Dangerous to Life or
Health (IDLH) Values, for Hydrogen
Bromide and Hydrogen Iodide
Centers for Disease Control and
Prevention (CDC), Department of Health
and Human Services (HHS).
ACTION: Request for comment.
AGENCY:
The National Institute for
Occupational Safety and Health
(NIOSH) in the Centers for Disease
Control and Prevention (CDC), an
SUMMARY:
VerDate Sep<11>2014
18:01 Jun 21, 2023
Jkt 259001
Operating Division of the Department of
Health and Human Services (HHS),
requests public comment and technical
review on two (2) draft Immediately
Dangerous to Life or Health (IDLH)
Value Profiles regarding the chemicals
hydrogen bromide (CAS# 10035–10–6)
and hydrogen iodide (CAS# 10034–85–
2).
DATES: Electronic or written comments
must be received by August 21, 2023.
ADDRESSES: You may submit comments,
identified by docket number CDC–
2019–0093 and docket number NIOSH–
156–E, by either of the following
methods:
• Federal eRulemaking Portal:
https://www.regulations.gov. Follow the
instructions for submitting comments.
• Mail: National Institute for
Occupational Safety and Health, NIOSH
Docket Office, 1090 Tusculum Avenue,
MS C–34, Cincinnati, Ohio 45226–1998.
Instructions: All information received
in response to this notice must include
the agency name and docket number
(CDC–2019–0093; NIOSH–156–E). All
relevant comments, including any
personal information provided, will be
posted without change to https://
www.regulations.gov. Do not submit
comments by email. CDC does not
accept comments by email. For access to
the docket to read background
documents or comments received, go to
https://www.regulations.gov.
FOR FURTHER INFORMATION CONTACT: R.
Todd Niemeier, Ph.D., National Institute
for Occupational Safety and Health,
MS–C15, 1090 Tusculum Avenue,
Cincinnati, OH 45226. Telephone: (513)
533–8166.
SUPPLEMENTARY INFORMATION: NIOSH is
requesting public comment and
including technical review on two (2)
draft IDLH Value Profiles. To facilitate
the review of these documents, NIOSH
requests comment on the following
specific questions for each draft Profile:
1. Does this document clearly outline
the health hazards associated with acute
(or short-term) exposures to the
chemical? If not, what specific
information is missing from the
document?
2. Are the rationale and logic behind
the derivation of an IDLH value for a
specific chemical clearly explained? If
not, what specific information is needed
to clarify the basis of the IDLH value?
3. Are the conclusions supported by
the data?
4. Are the tables clear and
appropriate?
5. Is the document organized
appropriately? If not, what
improvements are needed?
PO 00000
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Fmt 4703
Sfmt 4703
6. Are you aware of any scientific data
reported in government publications,
databases, peer-reviewed journals, or
other sources that should be included
within this document? The draft IDLH
Value Profiles were developed to
provide the scientific rationale behind
derivation of IDLH values for the
following chemicals:
Document
No.
Chemical
CAS
X–XX ........
X–XX ........
Hydrogen Bromide ..
Hydrogen Iodide .....
(# 10035–10–6)
(# 10034–85–2)
Each IDLH Value Profile provides a
detailed summary of the health hazards
of acute exposures to high airborne
concentrations of the chemical and the
rationale for the ILDH value.
Background: In 2013, NIOSH
published Current Intelligence Bulletin
(CIB) 66: Derivation of Immediately
Dangerous to Life or Health (IDLH)
Values [https://www.cdc.gov/niosh/docs/
2014-100/pdfs/2014-100.pdf] [NIOSH
2013]. The information presented in this
CIB represents the most recent update of
the scientific rationale and the
methodology (hereby referred to as the
IDLH methodology) used to derive IDLH
values. Since the establishment of the
IDLH values in the 1970s, NIOSH has
continued to review available scientific
data to improve the protocol used to
derive acute exposure guidelines, in
addition to the chemical specific IDLH
values.
IDLH values are based on health
effects considerations determined
through a critical assessment of the
toxicology and human health effects
data. This approach ensures that the
IDLH values reflect an airborne
concentration of a substance that
represents a high-risk situation that may
endanger workers’ lives or health.
The primary steps applied in the
establishment of an IDLH value include
the following:
1. Critical review of human and
animal toxicity data to identify
potentially relevant studies and
characterize the various lines of
evidence that can support the derivation
of the IDLH value;
2. Determination of a chemical’s mode
of action or description of how a
chemical exerts its toxic effects;
3. Application of duration
adjustments (time scaling) to determine
30-minute-equivalent exposure
concentrations and the conduct of other
dosimetry adjustments, as needed;
4. Experimental or other data to
establish a point of departure (POD)
such as lethal concentrations (e.g.,
LC50), lowest observed adverse effect
E:\FR\FM\22JNN1.SGM
22JNN1
Federal Register / Vol. 88, No. 119 / Thursday, June 22, 2023 / Notices
level (LOAEL), or no observed adverse
effect level (NOAEL);
5. Selection and application of an
uncertainty factor (UF) for POD or
critical adverse effect concentration,
identified from the available studies to
account for issues associated with
interspecies and intraspecies
differences, severity of the observed
effects, data quality, or data
insufficiencies; and
6. Development of the final
recommendation for the IDLH value
from the various alternative lines of
evidence, with use of a weight-ofevidence approach to all the data.
Reference
NIOSH [2013]. Current intelligence
bulletin 66: derivation of immediately
dangerous to life or health (IDLH)
values. Cincinnati, OH: U.S. Department
of Health and Human Services, Centers
for Disease Control and Prevention,
National Institute for Occupational
Safety and Health, DHHS (NIOSH)
Publication 2014–100.
John J. Howard,
Director, National Institute for Occupational
Safety and Health, Centers for Disease Control
and Prevention.
Times: 10 a.m.–6 p.m., EDT.
Place: Teleconference.
Agenda: To review and evaluate grant
applications.
For Further Information Contact:
Catherine Barrett, Ph.D., Scientific
Review Officer, National Center for
Chronic Disease Prevention and Health
Promotion, Centers for Disease Control
and Prevention, 4770 Buford Highway,
Mailstop S107–3, Atlanta, Georgia
30341–3717. Telephone: (770) 718–
7664; Email: CBarrett@cdc.gov.
The Director, Strategic Business
Initiatives Unit, Office of the Chief
Operating Officer, Centers for Disease
Control and Prevention, has been
delegated the authority to sign Federal
Register notices pertaining to
announcements of meetings and other
committee management activities, for
both the Centers for Disease Control and
Prevention and the Agency for Toxic
Substances and Disease Registry.
Kalwant Smagh,
Director, Strategic Business Initiatives Unit,
Office of the Chief Operating Officer, Centers
for Disease Control and Prevention.
[FR Doc. 2023–13234 Filed 6–21–23; 8:45 am]
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
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Centers for Medicare & Medicaid
Services
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
[Document Identifier: CMS–P–0015A]
Centers for Disease Control and
Prevention
Agency Information Collection
Activities: Submission for OMB
Review; Comment Request
ddrumheller on DSK120RN23PROD with NOTICES1
Notice of Closed Meeting
Pursuant to 5 U.S.C. 1009(d), notice is
hereby given of the following meeting.
The meeting will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), title 5 U.S.C.,
as amended, and the Determination of
the Director, Strategic Business
Initiatives Unit, Office of the Chief
Operating Officer, CDC, pursuant to
Public Law 92–463. The grant
applications and the discussions could
disclose confidential trade secrets or
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the grant applications, the disclosure of
which would constitute a clearly
unwarranted invasion of personal
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Name of Committee: Disease,
Disability, and Injury Prevention and
Control Special Emphasis Panel (SEP)DP24–004, Health Promotion and
Disease Prevention Research Centers.
Dates: August 28–September 1, 2023.
18:01 Jun 21, 2023
Jkt 259001
the estimated burden, ways to enhance
the quality, utility, and clarity of the
information to be collected, and the use
of automated collection techniques or
other forms of information technology to
minimize the information collection
burden.
Comments on the collection(s) of
information must be received by the
OMB desk officer by July 24, 2023.
ADDRESSES: Written comments and
recommendations for the proposed
information collection should be sent
within 30 days of publication of this
notice to www.reginfo.gov/public/do/
PRAMain. Find this particular
information collection by selecting
‘‘Currently under 30-day Review—Open
for Public Comments’’ or by using the
search function.
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statement and any related forms for the
proposed collection(s) summarized in
this notice, please access the CMS PRA
website by copying and pasting the
following web address into your web
browser: https://www.cms.gov/
Regulations-and-Guidance/Legislation/
PaperworkReductionActof1995/PRAListing.
DATES:
FOR FURTHER INFORMATION CONTACT:
[FR Doc. 2023–13251 Filed 6–21–23; 8:45 am]
VerDate Sep<11>2014
40827
Centers for Medicare &
Medicaid Services, Health and Human
Services (HHS).
ACTION: Notice.
AGENCY:
The Centers for Medicare &
Medicaid Services (CMS) is announcing
an opportunity for the public to
comment on CMS’ intention to collect
information from the public. Under the
Paperwork Reduction Act of 1995
(PRA), Federal agencies are required to
publish notice in the Federal Register
concerning each proposed collection of
information, including each proposed
extension or reinstatement of an existing
collection of information, and to allow
a second opportunity for public
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persons are invited to send comments
regarding the burden estimate or any
other aspect of this collection of
information, including the necessity and
utility of the proposed information
collection for the proper performance of
the agency’s functions, the accuracy of
SUMMARY:
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William Parham at (410) 786–4669.
Under the
Paperwork Reduction Act of 1995 (PRA)
(44 U.S.C. 3501–3520), federal agencies
must obtain approval from the Office of
Management and Budget (OMB) for each
collection of information they conduct
or sponsor. The term ‘‘collection of
information’’ is defined in 44 U.S.C.
3502(3) and 5 CFR 1320.3(c) and
includes agency requests or
requirements that members of the public
submit reports, keep records, or provide
information to a third party. Section
3506(c)(2)(A) of the PRA (44 U.S.C.
3506(c)(2)(A)) requires federal agencies
to publish a 30-day notice in the
Federal Register concerning each
proposed collection of information,
including each proposed extension or
reinstatement of an existing collection
of information, before submitting the
collection to OMB for approval. To
comply with this requirement, CMS is
publishing this notice that summarizes
the following proposed collection(s) of
information for public comment:
1. Type of Information Collection
Request: Revision of currently approved
collection; Title of Information
Collection: Medicare Current
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largest single payer of health care in the
United States. The agency plays a direct
or indirect role in administering health
insurance coverage for more than 120
SUPPLEMENTARY INFORMATION:
E:\FR\FM\22JNN1.SGM
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Agencies
[Federal Register Volume 88, Number 119 (Thursday, June 22, 2023)]
[Notices]
[Pages 40826-40827]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2023-13251]
=======================================================================
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
Centers for Disease Control and Prevention
[Docket Number CDC-2019-0093, NIOSH-156-E]
Request for Public Comment on Two Draft Immediately Dangerous to
Life or Health (IDLH) Values, for Hydrogen Bromide and Hydrogen Iodide
AGENCY: Centers for Disease Control and Prevention (CDC), Department of
Health and Human Services (HHS).
ACTION: Request for comment.
-----------------------------------------------------------------------
SUMMARY: The National Institute for Occupational Safety and Health
(NIOSH) in the Centers for Disease Control and Prevention (CDC), an
Operating Division of the Department of Health and Human Services
(HHS), requests public comment and technical review on two (2) draft
Immediately Dangerous to Life or Health (IDLH) Value Profiles regarding
the chemicals hydrogen bromide (CAS# 10035-10-6) and hydrogen iodide
(CAS# 10034-85-2).
DATES: Electronic or written comments must be received by August 21,
2023.
ADDRESSES: You may submit comments, identified by docket number CDC-
2019-0093 and docket number NIOSH-156-E, by either of the following
methods:
Federal eRulemaking Portal: https://www.regulations.gov.
Follow the instructions for submitting comments.
Mail: National Institute for Occupational Safety and
Health, NIOSH Docket Office, 1090 Tusculum Avenue, MS C-34, Cincinnati,
Ohio 45226-1998.
Instructions: All information received in response to this notice
must include the agency name and docket number (CDC-2019-0093; NIOSH-
156-E). All relevant comments, including any personal information
provided, will be posted without change to https://www.regulations.gov.
Do not submit comments by email. CDC does not accept comments by email.
For access to the docket to read background documents or comments
received, go to https://www.regulations.gov.
FOR FURTHER INFORMATION CONTACT: R. Todd Niemeier, Ph.D., National
Institute for Occupational Safety and Health, MS-C15, 1090 Tusculum
Avenue, Cincinnati, OH 45226. Telephone: (513) 533-8166.
SUPPLEMENTARY INFORMATION: NIOSH is requesting public comment and
including technical review on two (2) draft IDLH Value Profiles. To
facilitate the review of these documents, NIOSH requests comment on the
following specific questions for each draft Profile:
1. Does this document clearly outline the health hazards associated
with acute (or short-term) exposures to the chemical? If not, what
specific information is missing from the document?
2. Are the rationale and logic behind the derivation of an IDLH
value for a specific chemical clearly explained? If not, what specific
information is needed to clarify the basis of the IDLH value?
3. Are the conclusions supported by the data?
4. Are the tables clear and appropriate?
5. Is the document organized appropriately? If not, what
improvements are needed?
6. Are you aware of any scientific data reported in government
publications, databases, peer-reviewed journals, or other sources that
should be included within this document? The draft IDLH Value Profiles
were developed to provide the scientific rationale behind derivation of
IDLH values for the following chemicals:
------------------------------------------------------------------------
Document No. Chemical CAS
------------------------------------------------------------------------
X-XX..................... Hydrogen Bromide............ (# 10035-10-6)
X-XX..................... Hydrogen Iodide............. (# 10034-85-2)
------------------------------------------------------------------------
Each IDLH Value Profile provides a detailed summary of the health
hazards of acute exposures to high airborne concentrations of the
chemical and the rationale for the ILDH value.
Background: In 2013, NIOSH published Current Intelligence Bulletin
(CIB) 66: Derivation of Immediately Dangerous to Life or Health (IDLH)
Values [https://www.cdc.gov/niosh/docs/2014-100/pdfs/2014-100.pdf]
[NIOSH 2013]. The information presented in this CIB represents the most
recent update of the scientific rationale and the methodology (hereby
referred to as the IDLH methodology) used to derive IDLH values. Since
the establishment of the IDLH values in the 1970s, NIOSH has continued
to review available scientific data to improve the protocol used to
derive acute exposure guidelines, in addition to the chemical specific
IDLH values.
IDLH values are based on health effects considerations determined
through a critical assessment of the toxicology and human health
effects data. This approach ensures that the IDLH values reflect an
airborne concentration of a substance that represents a high-risk
situation that may endanger workers' lives or health.
The primary steps applied in the establishment of an IDLH value
include the following:
1. Critical review of human and animal toxicity data to identify
potentially relevant studies and characterize the various lines of
evidence that can support the derivation of the IDLH value;
2. Determination of a chemical's mode of action or description of
how a chemical exerts its toxic effects;
3. Application of duration adjustments (time scaling) to determine
30-minute-equivalent exposure concentrations and the conduct of other
dosimetry adjustments, as needed;
4. Experimental or other data to establish a point of departure
(POD) such as lethal concentrations (e.g., LC50), lowest observed
adverse effect
[[Page 40827]]
level (LOAEL), or no observed adverse effect level (NOAEL);
5. Selection and application of an uncertainty factor (UF) for POD
or critical adverse effect concentration, identified from the available
studies to account for issues associated with interspecies and
intraspecies differences, severity of the observed effects, data
quality, or data insufficiencies; and
6. Development of the final recommendation for the IDLH value from
the various alternative lines of evidence, with use of a weight-of-
evidence approach to all the data.
Reference
NIOSH [2013]. Current intelligence bulletin 66: derivation of
immediately dangerous to life or health (IDLH) values. Cincinnati, OH:
U.S. Department of Health and Human Services, Centers for Disease
Control and Prevention, National Institute for Occupational Safety and
Health, DHHS (NIOSH) Publication 2014-100.
John J. Howard,
Director, National Institute for Occupational Safety and Health,
Centers for Disease Control and Prevention.
[FR Doc. 2023-13251 Filed 6-21-23; 8:45 am]
BILLING CODE 4163-18-P