May 25, 2023 – Federal Register Recent Federal Regulation Documents

The Food and Drug Administration (FDA or Agency) is announcing the availability of a final guidance for industry entitled ``Use of Whole Slide Imaging in Nonclinical Toxicology Studies: Questions and Answers.'' This guidance represents FDA's current thinking on the use of whole slide images during good laboratory practice (GLP)-compliant toxicology studies. Documentation practices during generation, use, and retention of whole slide images have not been clearly defined and vary among nonclinical testing facilities. This question-and-answer document is intended to clarify FDA's recommendations concerning the management, documentation, and use of whole slide images in histopathology assessment and/or pathology peer review for nonclinical studies conducted in compliance with the GLP regulations. This guidance finalizes the draft guidance of the same title issued on April 8, 2022.

Pursuant to the Federal Advisory Committee Act, the Department of Health and Human Services (HHS) announces the following advisory committee meeting. This meeting is open to the public. The public is welcome to obtain the link to attend this meeting by following the instructions posted on the Committee website: https://ncvhs.hhs.gov/ meetings/full-committee-meeting-13/.

The Internet of Things (IoT) Advisory Board will meet Tuesday, July 18, 2023 and Wednesday, July 19, 2023; from 11:00 a.m. until 5:00 p.m., Eastern Time. All sessions will be open to the public.

The FAA proposes to adopt a new airworthiness directive (AD) for certain The Boeing Company Model 737-600, 737-700, and 737-800 series airplanes. This proposed AD was prompted by an evaluation by the design approval holder (DAH) indicating the fuselage skin at the double row of fasteners centered on certain stringers is subject to skin cracking. This proposed AD is intended to complete certain programs to support the airplane reaching its limit of validity (LOV). This proposed AD would require repetitive inspections for cracks of skin repairs at Stringer S-17, and corrective actions if necessary. The FAA is proposing this AD to address the unsafe condition on these products.

Pursuant to the provisions of the Privacy Act of 1974, as amended, notice is hereby given that the Farm Credit Administration (FCA or Agency) is amending an existing system of records, FCA-16 Examiner Training and Education RecordsFCA. The Examiner Training and Education RecordsFCA system is used to track pre-commissioned examiners' training and progression towards becoming commissioned examiners. The Agency is updating the notice to rename and broaden the overall purpose of the system, including maintaining performance related information for FCA examiners and is updating the categories of records and individuals maintained in the system to reflect that modified purpose.

This document directs that a referendum be conducted among eligible cranberry producers to determine whether they favor continuance of the marketing order regulating the handling of cranberries grown in the States of Massachusetts, Rhode Island, Connecticut, New Jersey, Wisconsin, Michigan, Minnesota, Oregon, Washington, and Long Island in the State of New York.

On February 28, 2022, the Agricultural Marketing Service (AMS) published a rule removing sixteen substances from the National List of Allowed and Prohibited Substances (National List). That document accidentally omitted nonorganic whey protein concentrate from the amendatory instructions. This document corrects the amendatory language, removing nonorganic whey protein concentrate from the National List, as intended in the previous document.

This is a Notice of the Presidential declaration of a major disaster for Public Assistance Only for the State of Tennessee (FEMA- 4712-DR), dated 05/17/2023. Incident: Severe Storms, Straight-line Winds, and Tornado. Incident Period: 03/01/2023 through 03/03/2023.

Usona Institute has applied to be registered as an importer of basic class(es) of controlled substance(s). Refer to SUPPLEMENTARY INFORMATION listed below for further drug information.

VA Cooperative Studies Program has applied to be registered as an importer of basic class(es) of controlled substance(s). Refer to SUPPLEMENTARY INFORMATION listed below for further drug information.

Royal Emerald Pharmaceuticals has applied to be registered as an importer of basic class(es) of controlled substance(s). Refer to SUPPLEMENTARY INFORMATION listed below for further drug information.

On August 15, 2022, notice was published on page 50159 of the Federal Register (volume 87, number 156) of determinations pertaining to certain objects to be included in an exhibition entitled ``The Tudors: Art and Majesty in Renaissance England.'' On December 29, 2022, notice was published on page 80246 of the Federal Register (volume 87, number 249) of determinations pertaining to a certain additional object to be included in the aforesaid exhibition. Notice is hereby given of the following determinations: I hereby determine that certain additional objects being imported from abroad pursuant to agreements with their foreign owners or custodians for temporary display in the aforesaid exhibition at the Fine Arts Museums of San Francisco, Legion of Honor, San Francisco, California, and at possible additional exhibitions or venues yet to be determined, are of cultural significance, and, further, that their temporary exhibition or display within the United States as aforementioned is in the national interest. I have ordered that Public Notice of these determinations be published in the Federal Register.

United States Pharmacopeial has applied to be registered as an importer of basic class(es) of controlled substance(s). Refer to SUPPLEMENTARY INFORMATION listed below for further drug information.