Availability of Four Draft Toxicological Profiles, 8427-8428 [2023-02754]

Download as PDF Federal Register / Vol. 88, No. 27 / Thursday, February 9, 2023 / Notices DEPARTMENT OF HEALTH AND HUMAN SERVICES Agency for Healthcare Research and Quality Meeting of the National Advisory Council for Healthcare Research and Quality Agency for Healthcare Research and Quality (AHRQ), Department of Health and Human Services. ACTION: Notice of public meeting. AGENCY: This notice announces a meeting of the National Advisory Council for Healthcare Research and Quality. SUMMARY: The meeting will be held on Monday, March 6, 2023, from 11:30 a.m. to 3:00 p.m. ADDRESSES: The meeting will be held virtually. DATES: FOR FURTHER INFORMATION CONTACT: Jaime Zimmerman, Designated Management Official, at the Agency for Healthcare Research and Quality, 5600 Fishers Lane, Mail Stop 06E37A, Rockville, Maryland 20857, (301) 427– 1456. For press-related information, please contact Bruce Seeman at (301) 427–1998 or Bruce.Seeman@ AHRQ.hhs.gov. Closed captioning will be provided during the meeting. If another reasonable accommodation for a disability is needed, please contact the Food and Drug Administration (FDA) Office of Equal Employment Opportunity and Diversity Management on (301) 827–4840, no later than Monday, February 27, 2023. The agenda, roster, and minutes will be available from Jenny Griffith, Committee Management Officer, Agency for Healthcare Research and Quality, 5600 Fishers Lane, Rockville, Maryland 20857. Jenny Griffith’s phone number is (240) 446–6799. SUPPLEMENTARY INFORMATION: khammond on DSKJM1Z7X2PROD with NOTICES I. Purpose In accordance with section 10(a) of the Federal Advisory Committee Act, 5 U.S.C. App., this notice announces a meeting of the National Advisory Council for Healthcare Research and Quality (the Council). The Council is authorized by Section 941 of the Public Health Service Act, 42 U.S.C. 299c. In accordance with its statutory mandate, the Council is to advise the Secretary of the Department of Health and Human Services and the Director of AHRQ on matters related to AHRQ’s conduct of its mission including providing guidance on (A) priorities for health care research, VerDate Sep<11>2014 16:28 Feb 08, 2023 Jkt 259001 (B) the field of health care research including training needs and information dissemination on health care quality and (C) the role of the Agency in light of private sector activity and opportunities for public private partnerships. The Council is composed of members of the public, appointed by the Secretary, and Federal ex-officio members specified in the authorizing legislation. II. Agenda On Monday, March 6, 2023, NAC members will meet to conduct preparatory work prior to convening the Council meeting at 11:30 a.m., with the call to order by the Council Chair, an introduction of NAC members, and approval of previous Council summary notes. The NAC members will then receive an update from the AHRQ Director, including a follow up discussion on private capital and engaging health system executive leadership. The agenda will also include (1) an update and discussion by NAC members on AHRQ’s Patient Safety Framework and the Patient Safety Action Alliance’s efforts to promote Safer Together: A National Patient Safety Action Plan and (2) a report out and discussion about Long Covid and addressing health system fragmentation. The meeting is open to the public and will adjourn at 3:00 p.m. For information regarding how to access the meeting as well as other meeting details, including information on how to make a public comment, please go to https:// www.ahrq.gov/news/events/nac/. The final agenda will be available on the AHRQ website no later than Monday February 27, 2023. Dated: February 3, 2023. Marquita Cullom, Associate Director. [FR Doc. 2023–02724 Filed 2–8–23; 8:45 am] BILLING CODE 4160–90–P DEPARTMENT OF HEALTH AND HUMAN SERVICES Agency for Toxic Substances and Disease Registry [Docket No. ATSDR–2022–0006] Availability of Four Draft Toxicological Profiles Agency for Toxic Substances and Disease Registry (ATSDR), Department of Health and Human Services (HHS). ACTION: Notice with comment period. AGENCY: The Agency for Toxic Substances and Disease Registry SUMMARY: PO 00000 Frm 00031 Fmt 4703 Sfmt 4703 8427 (ATSDR), within the Department of Health and Human Services (HHS), announces the opening of a docket to obtain comments on drafts of four updated toxicological profiles: Cobalt, Hexachlorocyclohexanes, 1,1,1Trichloroethane, and Vinyl Chloride. Written comments must be received on or before May 10, 2023. DATES: You may submit comments, identified by Docket Number ATSDR– 2022–0006, by either of the following methods: • Federal eRulemaking Portal: www.regulations.gov. Follow the instructions for submitting comments. • Mail: Toxicology Section, Office of Innovation and Analytics, Agency for Toxic Substances and Disease Registry, 4770 Buford Highway, Mail Stop S102– 1, Atlanta, GA 30341–3717. Attn: Docket No. ATSDR–2022–0006. Instructions: All submissions must include the Agency name and Docket Number. All relevant comments received will be posted without change to www.regulations.gov, including any personal information provided. Do not submit comments by email. ATSDR does not accept comments by email. For access to the docket to read background documents or comments received, go to www.regulations.gov. ADDRESSES: N. Roney, Agency for Toxic Substances and Disease Registry, 4770 Buford Highway, Mail Stop S102–1, Atlanta, GA 30329–4027; Email: ATSDRToxProfileFRNs@cdc.gov; Telephone: 800–232–4636. FOR FURTHER INFORMATION CONTACT: ATSDR has prepared drafts of four updated toxicological profiles based on current understanding of the health effects and availability of new studies and other information since their initial release. All toxicological profiles issued as ‘‘Drafts for Public Comment’’ represent the result of ATSDR’s evidence-based evaluations to provide important toxicological information on priority hazardous substances to the public and health professionals. ATSDR considers key studies for these substances during the profile development process, using a systematic review approach. To that end, ATSDR is seeking public comments and additional information or reports on studies about the health effects of these four substances for review and potential inclusion in the profiles. ATSDR will evaluate the quality and relevance of such data or studies for possible inclusion in the profile. SUPPLEMENTARY INFORMATION: E:\FR\FM\09FEN1.SGM 09FEN1 8428 Federal Register / Vol. 88, No. 27 / Thursday, February 9, 2023 / Notices Public Participation Interested persons or organizations are invited to participate by submitting written views, information, and data. Comments received, including attachments and other supporting materials, are part of the public record and are subject to public disclosure. Comments will be posted on www.regulations.gov. Therefore, do not include any information in your comment or supporting materials that you consider confidential or inappropriate for public disclosure. If you include your name, contact information, or other information that identifies you in the body of your comments, that information will be on public display. Do not submit comments by email. ATSDR does not accept comments by email. ATSDR will review all submissions and may choose to redact or withhold submissions containing private or proprietary information such as Social Security numbers, medical information, inappropriate language, or duplicate/ near duplicate examples of a mass-mail campaign. ATSDR will carefully review and consider all comments submitted in preparation of the Final Toxicological Profiles and may revise the profiles as appropriate. inventory of literature, research, and studies on the health effects of toxic substances (CERCLA Section 104(i)(1)(B); 42 U.S.C. 9604(i)(1)(B)); to respond to requests for health consultations (CERCLA Section 104(i)(4); 42 U.S.C. 9604(i)(4)); and to support the site-specific response actions conducted by the agency (CERCLA Section 104(i)(6); 42 U.S.C. 9604(i)(6)). Public nominations for substances from the SPL (or other substances) for toxicological profile development were requested on April 18, 2018 (83 FR 17177). ATSDR has now prepared drafts of four updated toxicological profiles based on current understanding of the health effects and availability of new studies and other information since their initial release. Availability The Draft Toxicological Profiles are available online at www.regulations.gov, Docket No. ATSDR–2022–0006 and at www.atsdr.cdc.gov/ToxProfiles. Determinants of Health to Promote Health Equity and Reduce Health Disparities in Chronic Diseases. Dates: April 19–20, 2023. Times: 10:00 a.m.–6:00 p.m., EDT. Place: Teleconference. Agenda: To review and evaluate grant applications. For Further Information Contact: Catherine Barrett, Ph.D., Scientific Review Officer, National Center for Chronic Disease Prevention and Health Promotion, CDC, 4770 Buford Highway, Mailstop S107–3, Atlanta, Georgia 30341–3717; Telephone: (770) 718– 7664; Email: CBarrett@cdc.gov. The Director, Strategic Business Initiatives Unit, Office of the Chief Operating Officer, Centers for Disease Control and Prevention, has been delegated the authority to sign Federal Register notices pertaining to announcements of meetings and other committee management activities, for both the Centers for Disease Control and Prevention and the Agency for Toxic Substances and Disease Registry. Donata Green, Acting Associate Director, Office of Policy, Planning and Partnerships, Agency for Toxic Substances and Disease Registry. Kalwant Smagh, Director, Strategic Business Initiatives Unit, Office of the Chief Operating Officer, Centers for Disease Control and Prevention. [FR Doc. 2023–02754 Filed 2–8–23; 8:45 am] [FR Doc. 2023–02747 Filed 2–8–23; 8:45 am] BILLING CODE 4163–70–P BILLING CODE 4163–18–P DEPARTMENT OF HEALTH AND HUMAN SERVICES DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Centers for Disease Control and Prevention Notice of Closed Meeting [Docket No. CDC–2022–0003] Pursuant to 5 U.S.C. 1009(d), notice is hereby given of the following meeting. The meeting will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended, and the Determination of the Director, Strategic Business Initiatives Unit, Office of the Chief Operating Officer, CDC, pursuant to Public Law 117–286. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP)— DP23–001, Panel B, Assessing the Effectiveness of Programs, Policies, or Practices that Affect Social Policy Statement for Biosafety Level 4/ Animal Biosafety Level 4 Laboratory Verification; Notice of Availability khammond on DSKJM1Z7X2PROD with NOTICES Legislative Background The Superfund Amendments and Reauthorization Act of 1986 (SARA) [42 U.S.C. 9601 et seq.] amended the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA or Superfund) [42 U.S.C. 9601 et seq.] by establishing certain requirements for ATSDR and the U.S. Environmental Protection Agency (EPA) regarding the hazardous substances most commonly found at facilities on the CERCLA National Priorities List. Among these statutory requirements is a mandate for the Administrator of ATSDR to prepare toxicological profiles for each substance included on the priority list of hazardous substances [also called the Substance Priority List (SPL)]. This list identifies 275 hazardous substances that ATSDR has determined pose the most significant potential threat to human health. The SPL is available online at www.atsdr.cdc.gov/spl. ATSDR is also mandated to revise and publish updated toxicological profiles, as necessary, to reflect updated health effects and other information. In addition, CERCLA provides ATSDR with the authority to prepare toxicological profiles for substances not found on the SPL. CERCLA authorizes ATSDR to establish and maintain an VerDate Sep<11>2014 16:28 Feb 08, 2023 Jkt 259001 PO 00000 Frm 00032 Fmt 4703 Sfmt 4703 Centers for Disease Control and Prevention (CDC), Department of Health and Human Services (HHS). ACTION: Notice. AGENCY: The Centers for Disease Control and Prevention (CDC), in the Department of Health and Human Services (HHS), announces the availability and implementation of the final Biosafety Level 4 (BSL–4)/Animal BSL–4 (ABSL–4) verification policy. The policy statement assists individuals and entities in verifying that the facility design parameters and operational procedures, including heating, ventilation, and air conditioning (HVAC) systems, in BSL–4 and/or ABSL–4 laboratories are functioning as intended to meet the biosafety sufficiency requirement in the HHS/ CDC select agent and toxin regulations. SUMMARY: E:\FR\FM\09FEN1.SGM 09FEN1

Agencies

[Federal Register Volume 88, Number 27 (Thursday, February 9, 2023)]
[Notices]
[Pages 8427-8428]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2023-02754]


-----------------------------------------------------------------------

DEPARTMENT OF HEALTH AND HUMAN SERVICES

Agency for Toxic Substances and Disease Registry

[Docket No. ATSDR-2022-0006]


Availability of Four Draft Toxicological Profiles

AGENCY: Agency for Toxic Substances and Disease Registry (ATSDR), 
Department of Health and Human Services (HHS).

ACTION: Notice with comment period.

-----------------------------------------------------------------------

SUMMARY: The Agency for Toxic Substances and Disease Registry (ATSDR), 
within the Department of Health and Human Services (HHS), announces the 
opening of a docket to obtain comments on drafts of four updated 
toxicological profiles: Cobalt, Hexachlorocyclohexanes, 1,1,1-
Trichloroethane, and Vinyl Chloride.

DATES: Written comments must be received on or before May 10, 2023.

ADDRESSES: You may submit comments, identified by Docket Number ATSDR-
2022-0006, by either of the following methods:
     Federal eRulemaking Portal: www.regulations.gov. Follow 
the instructions for submitting comments.
     Mail: Toxicology Section, Office of Innovation and 
Analytics, Agency for Toxic Substances and Disease Registry, 4770 
Buford Highway, Mail Stop S102-1, Atlanta, GA 30341-3717. Attn: Docket 
No. ATSDR-2022-0006.
    Instructions: All submissions must include the Agency name and 
Docket Number. All relevant comments received will be posted without 
change to www.regulations.gov, including any personal information 
provided. Do not submit comments by email. ATSDR does not accept 
comments by email. For access to the docket to read background 
documents or comments received, go to www.regulations.gov.

FOR FURTHER INFORMATION CONTACT: N. Roney, Agency for Toxic Substances 
and Disease Registry, 4770 Buford Highway, Mail Stop S102-1, Atlanta, 
GA 30329-4027; Email: [email protected]; Telephone: 800-232-
4636.

SUPPLEMENTARY INFORMATION: ATSDR has prepared drafts of four updated 
toxicological profiles based on current understanding of the health 
effects and availability of new studies and other information since 
their initial release. All toxicological profiles issued as ``Drafts 
for Public Comment'' represent the result of ATSDR's evidence-based 
evaluations to provide important toxicological information on priority 
hazardous substances to the public and health professionals. ATSDR 
considers key studies for these substances during the profile 
development process, using a systematic review approach. To that end, 
ATSDR is seeking public comments and additional information or reports 
on studies about the health effects of these four substances for review 
and potential inclusion in the profiles. ATSDR will evaluate the 
quality and relevance of such data or studies for possible inclusion in 
the profile.

[[Page 8428]]

Public Participation

    Interested persons or organizations are invited to participate by 
submitting written views, information, and data. Comments received, 
including attachments and other supporting materials, are part of the 
public record and are subject to public disclosure. Comments will be 
posted on www.regulations.gov. Therefore, do not include any 
information in your comment or supporting materials that you consider 
confidential or inappropriate for public disclosure. If you include 
your name, contact information, or other information that identifies 
you in the body of your comments, that information will be on public 
display. Do not submit comments by email. ATSDR does not accept 
comments by email. ATSDR will review all submissions and may choose to 
redact or withhold submissions containing private or proprietary 
information such as Social Security numbers, medical information, 
inappropriate language, or duplicate/near duplicate examples of a mass-
mail campaign. ATSDR will carefully review and consider all comments 
submitted in preparation of the Final Toxicological Profiles and may 
revise the profiles as appropriate.

Legislative Background

    The Superfund Amendments and Reauthorization Act of 1986 (SARA) [42 
U.S.C. 9601 et seq.] amended the Comprehensive Environmental Response, 
Compensation, and Liability Act of 1980 (CERCLA or Superfund) [42 
U.S.C. 9601 et seq.] by establishing certain requirements for ATSDR and 
the U.S. Environmental Protection Agency (EPA) regarding the hazardous 
substances most commonly found at facilities on the CERCLA National 
Priorities List. Among these statutory requirements is a mandate for 
the Administrator of ATSDR to prepare toxicological profiles for each 
substance included on the priority list of hazardous substances [also 
called the Substance Priority List (SPL)]. This list identifies 275 
hazardous substances that ATSDR has determined pose the most 
significant potential threat to human health. The SPL is available 
online at www.atsdr.cdc.gov/spl. ATSDR is also mandated to revise and 
publish updated toxicological profiles, as necessary, to reflect 
updated health effects and other information.
    In addition, CERCLA provides ATSDR with the authority to prepare 
toxicological profiles for substances not found on the SPL. CERCLA 
authorizes ATSDR to establish and maintain an inventory of literature, 
research, and studies on the health effects of toxic substances (CERCLA 
Section 104(i)(1)(B); 42 U.S.C. 9604(i)(1)(B)); to respond to requests 
for health consultations (CERCLA Section 104(i)(4); 42 U.S.C. 
9604(i)(4)); and to support the site-specific response actions 
conducted by the agency (CERCLA Section 104(i)(6); 42 U.S.C. 
9604(i)(6)). Public nominations for substances from the SPL (or other 
substances) for toxicological profile development were requested on 
April 18, 2018 (83 FR 17177).
    ATSDR has now prepared drafts of four updated toxicological 
profiles based on current understanding of the health effects and 
availability of new studies and other information since their initial 
release.

Availability

    The Draft Toxicological Profiles are available online at 
www.regulations.gov, Docket No. ATSDR-2022-0006 and at 
www.atsdr.cdc.gov/ToxProfiles.

Donata Green,
Acting Associate Director, Office of Policy, Planning and Partnerships, 
Agency for Toxic Substances and Disease Registry.
[FR Doc. 2023-02754 Filed 2-8-23; 8:45 am]
BILLING CODE 4163-70-P
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