National Institute of Biomedical Imaging and Bioengineering; Notice of Meeting, 77129-77130 [2022-27291]
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Federal Register / Vol. 87, No. 241 / Friday, December 16, 2022 / Notices
• R01 CA231940–01A1, ‘‘Regulation
of Tet2 in programming mammary stem
cell fate,’’ submitted to NCI, NIH, on 06/
26/2018.
• R01 CA233941–01, ‘‘DHA directs
epigenetic programming in triplenegative breast cancer,’’ submitted to
NCI, NIH, on 02/05/2018.
• R01 GM121775–01, ‘‘The role of
Tet2 regulation in directing mammary
stem cell fate,’’ submitted to the
National Institute of General Medical
Sciences (NIGMS), NIH, on 02/05/2016.
• R35 GM124972–01, ‘‘Novel role of
microRNA in directing stem cell fate
decision,’’ submitted to NIGMS, NIH, on
11/04/2016.
Specifically, ORI found that
Respondent knowingly, intentionally, or
recklessly falsified and/or fabricated
data from the same mouse models or
cell lines by reusing the data, with or
without manipulation, to represent
unrelated experiments from different
mouse models or cell lines with
different treatments in three hundred
eighty-four (384) figure panels in sixteen
(16) grant applications.
In addition, ORI found that
Respondent engaged in research
misconduct by knowingly,
intentionally, or recklessly falsifying
and/or fabricating data included in two
(2) PHS-supported published papers.
Respondent neither admits nor denies
ORI’s findings with respect to the two
(2) published papers:
• Chang CC, Wu MJ, Yang JY,
Camarillo IG, Chang CJ. Leptin-STAT3–
G9a signaling promotes obesitymediated breast cancer progression.
Cancer Res. 2015 Jun 1;75(11):2375–86.
doi: 10.1158/0008–5472.CAN–14–3076.
• Wu MJ, Kim MR, Chen YS, Yang JY,
Chang CJ. Retinoic acid directs breast
cancer cell state changes through
regulation of TET2–PKCz pathway.
Oncogene 2017 Jun 1;36(22):3193–206.
doi: 10.1038/onc.2016.467.
Specifically, ORI found that
Respondent intentionally, knowingly, or
recklessly falsified and/or fabricated:
• confocal image data for generation,
differentiation, and drug sensitivity of
cancer stem cells (CSC) in mouse
models and cell lines by reusing the
data, with or without manipulation, and
relabeling them to represent different
experiments in fifty-four (54) figure
panels included in fifteen (15) grant
applications;
• Western blot and co-IP blot images
for different protein expression in
different mouse models and cell lines by
reusing the images, with or without
manipulation, and relabeling them to
represent different experiments in
eighty-one (81) figure panels in thirteen
(13) grant applications;
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• figures, charts, and graphs reporting
gene expression related results for the
global or tissue-related gene expression
in mouse models and cell lines with
drug treatments by reusing them, with
or without manipulation, and relabeling
them to represent different experiments
in one hundred nineteen (119) figure
panels in fifteen (15) grant applications
and two (2) published papers;
• figures, charts, and graphs about
cellular experiment related results for
different mouse models and cell lines by
reusing them, with or without
manipulation, and relabeling them to
represent different experiments in fortytwo (42) figure panels in thirteen (13)
grant applications;
• photomicrographs for different
results from different mouse models and
cell lines by reusing them, with or
without manipulation, and relabeling
them to represent different experiments
in eighty-five (85) figure panels in
fifteen (15) grant applications;
• CSC frequency (xenograft tumor
formation) data reporting different
results from either mouse models or cell
lines by reusing and relabeling the same
data to represent different experiments
in three (3) figure panels in three (3)
grant applications.
Dr. Chang entered into a Voluntary
Exclusion Agreement (Agreement) and
voluntarily agreed to the following:
(1) Respondent will exclude herself
voluntarily for a period of ten (10) years
beginning on December 7, 2022 (the
‘‘Exclusion Period’’) from any
contracting or subcontracting with any
agency of the United States Government
and from eligibility for or involvement
in nonprocurement or procurement
transactions referred to as ‘‘covered
transactions’’ in 2 CFR parts 180 and
376 (collectively the ‘‘Debarment
Regulations’’).
(2) During the Exclusion Period,
Respondent will exclude herself
voluntarily from serving in any advisory
or consultant capacity to PHS including,
but not limited to, service on any PHS
advisory committee, board, and/or peer
review committee.
(3) Respondent will request that the
following papers be corrected:
• Cancer Res. 2015 Jun 1;
75(11):2375–86.
• Oncogene 2017 Jun 1; 36(22):3193–
206.
Respondent will copy ORI and the
Research Integrity Officer at PU on the
correspondence with the journal(s).
Dated: December 13, 2022.
Wanda K. Jones,
Acting Director, Office of Research Integrity,
Office of the Assistant Secretary for Health.
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77129
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
National Institute of Allergy and
Infectious Diseases; Notice of Closed
Meeting
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended, notice is hereby given of the
following meeting.
The meeting will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The contract proposals and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the contract
proposals, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: National Institute of
Allergy and Infectious Diseases Special
Emphasis Panel HHS–NIH–CDC–SBIR PHS
2020–1 Phase II: Antiviral drugs to cure
chronic hepatitis B virus infection (Topic 84)
Date: January 18, 2023.
Time: 10:00 a.m. to 12:00 p.m.
Agenda: To review and evaluate contract
proposals.
Place: National Institute of Allergy and
Infectious Diseases, National Institutes of
Health 5601 Fishers Lane, Room 3F36
Rockville, MD 20892, (Virtual Meeting).
Contact Person: Noto K. Dutta, Ph.D.,
Scientific Review Officer, Scientific Review
Program Division of Extramural Activities,
National Institute of Allergy and Infectious
Diseases, National Institutes of Health 5601
Fishers Lane, Room 3F36, Rockville, MD
20852, 240–669–2857 noton.dutta@nih.gov.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.855, Allergy, Immunology,
and Transplantation Research; 93.856,
Microbiology and Infectious Diseases
Research, National Institutes of Health, HHS)
Dated: December 12, 2022.
Tyeshia M. Roberson-Curtis,
Program Analyst, Office of Federal Advisory
Committee Policy.
[FR Doc. 2022–27285 Filed 12–15–22; 8:45 am]
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
National Institute of Biomedical
Imaging and Bioengineering; Notice of
Meeting
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended, notice is hereby given of a
meeting of the National Advisory
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77130
Federal Register / Vol. 87, No. 241 / Friday, December 16, 2022 / Notices
Council for Biomedical Imaging and
Bioengineering.
The meeting will be open to the
public by videocast as indicated below.
The meeting will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the grant
applications and/or contract proposals,
the disclosure of which would
constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: National Advisory
Council for Biomedical Imaging and
Bioengineering NACBIB, January 2023.
Date: January 25, 2023.
Open: 12:00 p.m. to 2:30 p.m.
Agenda: Report from the Institute Director,
Council Members and other Institute Staff.
Place: National Institutes of Health,
Democracy II, 6707 Democracy Boulevard,
Bethesda, MD 20892 (Virtual Meeting).
Closed: 2:45 p.m. to 4:00 p.m.
Agenda: To review and evaluate grant
applications and/or proposals.
Place: National Institutes of Health,
Democracy II, 6707 Democracy Boulevard,
Bethesda, MD 20892 (Virtual Meeting).
Contact Person: David T. George, Ph.D.,
Associate Director for Research
Administration, Office of Research
Administration, National Institute of
Biomedical Imaging and Bioengineering,
6707 Democracy Boulevard, Room 920,
Bethesda, MD 20892, georged@mail.nih.gov.
Any interested person may file written
comments with the committee by forwarding
the statement to the Contact Person listed on
this notice. The statement should include the
name, address, telephone number and when
applicable, the business or professional
affiliation of the interested person.
Information is also available on the
Institute’s/Center’s home page: https://
www.nibib.nih.gov/about-nibib/advisorycouncil, where an agenda and any additional
information for the meeting will be posted
when available.
Dated: December 13, 2022.
Victoria E. Townsend,
Program Analyst, Office of Federal Advisory
Committee Policy.
[FR Doc. 2022–27291 Filed 12–15–22; 8:45 am]
BILLING CODE 4140–01–P
lotter on DSK11XQN23PROD with NOTICES1
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
Center for Scientific Review; Notice of
Closed Meeting
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
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amended, notice is hereby given of the
following meeting.
The meeting will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: Center for Scientific
Review Special Emphasis Panel; Vascular
and Hematology Meeting.
Date: January 11, 2023.
Time: 9:00 a.m. to 10:00 a.m.
Agenda: To review and evaluate grant
applications.
Place: National Institutes of Health,
Rockledge II, 6701 Rockledge Drive,
Bethesda, MD 20892 (Virtual Meeting).
Contact Person: Dmitri V. Gnatenko, Ph.D.,
Scientific Review Officer, Center for
Scientific Review, National Institutes of
Health, 6701 Rockledge Drive, Bethesda, MD
20892, (301) 867–5309, gnatenkod2@nih.gov.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.306, Comparative Medicine;
93.333, Clinical Research, 93.306, 93.333,
93.337, 93.393–93.396, 93.837–93.844,
93.846–93.878, 93.892, 93.893, National
Institutes of Health, HHS)
Dated: December 12, 2022.
Tyeshia M. Roberson-Curtis,
Program Analyst, Office of Federal Advisory
Committee Policy.
[FR Doc. 2022–27286 Filed 12–15–22; 8:45 am]
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
National Institute of Allergy and
Infectious Disease; Notice of Closed
Meeting
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended, notice is hereby given of the
following meeting.
The meeting will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The contract proposals and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the contract
proposals, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
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Name of Committee: National Institute of
Allergy and Infectious Diseases Special
Emphasis Panel; HHS–NIH–CDC–SBIR PHS
2023–1 Phase I: Artificial Intelligence to
Improve Clinical Microscopy for Diagnosis of
Infectious Diseases (Topic 121).
Date: January 17, 2023.
Time: 10:00 a.m. to 1:00 p.m.
Agenda: To review and evaluate contract
proposals.
Place: National Institute of Allergy and
Infectious Diseases, National Institutes of
Health, 5601 Fishers Lane, Room 3F36,
Rockville, MD 20892 (Virtual Meeting).
Contact Person: Noto K. Dutta, Ph.D.,
Scientific Review Officer, Scientific Review
Program, Division of Extramural Activities,
National Institute of Allergy and Infectious
Diseases, National Institutes of Health, 5601
Fishers Lane, Room 3F36, Rockville, MD
20852, 240–669–2857, noton.dutta@nih.gov.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.855, Allergy, Immunology,
and Transplantation Research; 93.856,
Microbiology and Infectious Diseases
Research, National Institutes of Health, HHS)
Dated: December 12, 2022.
Tyeshia M. Roberson-Curtis,
Program Analyst, Office of Federal Advisory
Committee Policy.
[FR Doc. 2022–27284 Filed 12–15–22; 8:45 am]
BILLING CODE 4140–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
National Institute of Neurological
Disorders and Stroke; Notice of Closed
Meetings
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended, notice is hereby given of the
following meetings.
The meetings will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: National Institute of
Neurological Disorders and Stroke Special
Emphasis Panel; Pragmatic Clinical Trials to
Decrease and Prevent VCID Outcomes.
Date: January 11, 2023.
Time: 12:00 p.m. to 1:30 p.m.
Agenda: To review and evaluate grant
applications.
Place: National Institutes of Health,
Neuroscience Center, 6001 Executive
Boulevard, Rockville, MD 20852 (Virtual
Meeting)
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Agencies
[Federal Register Volume 87, Number 241 (Friday, December 16, 2022)]
[Notices]
[Pages 77129-77130]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2022-27291]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health
National Institute of Biomedical Imaging and Bioengineering;
Notice of Meeting
Pursuant to section 10(d) of the Federal Advisory Committee Act, as
amended, notice is hereby given of a meeting of the National Advisory
[[Page 77130]]
Council for Biomedical Imaging and Bioengineering.
The meeting will be open to the public by videocast as indicated
below.
The meeting will be closed to the public in accordance with the
provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5
U.S.C., as amended. The grant applications and the discussions could
disclose confidential trade secrets or commercial property such as
patentable material, and personal information concerning individuals
associated with the grant applications and/or contract proposals, the
disclosure of which would constitute a clearly unwarranted invasion of
personal privacy.
Name of Committee: National Advisory Council for Biomedical
Imaging and Bioengineering NACBIB, January 2023.
Date: January 25, 2023.
Open: 12:00 p.m. to 2:30 p.m.
Agenda: Report from the Institute Director, Council Members and
other Institute Staff.
Place: National Institutes of Health, Democracy II, 6707
Democracy Boulevard, Bethesda, MD 20892 (Virtual Meeting).
Closed: 2:45 p.m. to 4:00 p.m.
Agenda: To review and evaluate grant applications and/or
proposals.
Place: National Institutes of Health, Democracy II, 6707
Democracy Boulevard, Bethesda, MD 20892 (Virtual Meeting).
Contact Person: David T. George, Ph.D., Associate Director for
Research Administration, Office of Research Administration, National
Institute of Biomedical Imaging and Bioengineering, 6707 Democracy
Boulevard, Room 920, Bethesda, MD 20892, [email protected].
Any interested person may file written comments with the
committee by forwarding the statement to the Contact Person listed
on this notice. The statement should include the name, address,
telephone number and when applicable, the business or professional
affiliation of the interested person.
Information is also available on the Institute's/Center's home
page: https://www.nibib.nih.gov/about-nibib/advisory-council, where
an agenda and any additional information for the meeting will be
posted when available.
Dated: December 13, 2022.
Victoria E. Townsend,
Program Analyst, Office of Federal Advisory Committee Policy.
[FR Doc. 2022-27291 Filed 12-15-22; 8:45 am]
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