Medicine Bow-Routt National Forests and Thunder Basin National Grassland; Wyoming; 2020 Thunder Basin National Grassland Plan Amendment, 77426-77427 [2020-26563]
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77426
Federal Register / Vol. 85, No. 232 / Wednesday, December 2, 2020 / Notices
In addition to the risk assessment
summary, we wish to provide the
following information regarding our
evaluation.
Development and Safety of the FMD–
LL3B3D Leaderless FMD Virus
The FMD–LL3B3D leaderless vaccine
platform virus was created by deleting
the leader (L) and one of three 3B
genetic sequences of the FMD virus (L
is a part of the virus that determines
virulence), resulting in an attenuated
virus that is innocuous for cattle and
pigs but capable of growing in cell
culture.3 As a result, if the FMD–
LL3B3D leaderless virus were to escape
a manufacturing facility, it would be
incapable of causing FMD in any
animals exposed to it, nor could such
animals spread the virus to other
animals. In contrast, the risk of escape
from facilities using traditionally
virulent FMD viruses to manufacture
vaccine is why many countries restrict
FMD vaccine production to only local
endemic strains. The deletion of L and
the relevant 3B genetic sequence was
therefore a key consideration in our
evaluation.
Of similar importance was our review
of available data regarding virulence of
FMD–LL3B3D vaccines. Several FMD–
LL3B3D vaccine viruses have been
derived in vitro and characterized for
their virulence in cattle and pigs. The
cumulative data have shown that these
FMD–LL3B3D marker viruses are highly
attenuated in their natural hosts. Safety
studies involving direct inoculation of
live FMD–LL3B3D virus in cattle and
pigs (see table 1) showed a high
restriction of the novel vaccine virus to
replicate and resulted in no clinical
disease or transmission.4
TABLE 1—LIVE INNOCUITY STUDIES USING A VARIETY OF FMDLL3B3D VACCINE STRAINS IN CATTLE AND SWINE 1
Number of
animals
Construct
Inoculation route
Cattle:
FMD–LL3B3D–A24 Cruzeiro ............
FMD–LL3B3D–A24 Cruzeiro ............
FMD–LL3B3D–A24 Cruzeiro ............
Intralingual (7×106) ..................................
Aerosol (1×106 to 3×106) ........................
Aerosol and Contact/(1×106) ...................
2
3
9
•
•
•
•
•
No clinical disease.
No viral shedding.
No fever spikes.
No contact transmission.
Very limited if any immune response.
Swine:
FMD–LL3B3D–A24 Cruzeiro ............
FMD–LL3B3D–Asia1 Shamir ...........
FMD–LL3B3D–A Turkey 06 .............
FMD–LL3B3D–O1 Campos .............
FMD–LL3B3D–A Argentina ..............
FMD–LL3B3D–C3 Indaial ................
Heelbulb
Heelbulb
Heelbulb
Heelbulb
Heelbulb
Heelbulb
(1×105) ................
(1×106) ................
(1×106) ................
(1×106) ................
(2×106) ................
(2.8×106) ..............
4
5
5
4
4
4
•
•
•
•
•
No clinical disease.
No viral shedding.
No fever spikes.
No contact transmission.
Very limited if any immune response.
1 Data
and
and
and
and
and
and
Contact
Contact
Contact
Contact
Contact
Contact
Results
prepared by Foreign Animal Disease Research Unit, USDA/ARS, Plum Island Animal Disease Center.
We are therefore reopening the
comment period on Docket No. APHIS–
2020–0054 for an additional 30 days.
This action will allow interested
persons to prepare and submit
comments on the additional information
we provided. We will also consider all
comments received between September
14, 2020, and the date of this notice.
DEPARTMENT OF AGRICULTURE
Authority: 7 U.S.C. 1633, 7701–7772,
7781–7786, and 8301–8317; 21 U.S.C. 136
and 136a; 31 U.S.C. 9701; 7 CFR 2.22, 2.80,
and 371.4.
AGENCY:
Done in Washington, DC, this 25th day of
November 2020.
Mark Davidson,
Acting Administrator, Animal and Plant
Health Inspection Service.
[FR Doc. 2020–26560 Filed 12–1–20; 8:45 am]
BILLING CODE 3410–34–P
3 See the following studies for leaderless FMD
virus safety data: Uddowla S., et al. A Safe Footand-Mouth Disease Vaccine Platform with Two
Negative Markers for Differentiating Infected from
Vaccinated Animals. Journal of Virology Oct 2012,
86(21) 11675–11685: DOI: 10.1128/JVI.01254–12;
Eschbaumer M., et al. Foot-and-mouth disease virus
lacking the leader 2 protein and containing two
VerDate Sep<11>2014
17:39 Dec 01, 2020
Jkt 253001
Forest Service
Medicine Bow-Routt National Forests
and Thunder Basin National
Grassland; Wyoming; 2020 Thunder
Basin National Grassland Plan
Amendment
Forest Service, USDA.
Notice of Grassland Plan
amendment approval.
ACTION:
Russell M. Bacon, Forest
Supervisor for the Medicine Bow-Routt
National Forests and Thunder Basin
National Grassland, Rocky Mountain
Region, signed the final Record of
Decision (ROD) for the 2020 Thunder
Basin National Grassland Land and
Resource Management Plan Amendment
(Grassland Plan amendment). The Final
ROD documents the rationale for
approving the Grassland Plan
amendment and is consistent with the
SUMMARY:
negative DIVA markers 3 (FMDV LL3B3D A24) is
fully attenuated in pigs. Pathogens. (2020) 17:1–8:
DOI: 10.3390/pathogens9020129; Hardham, John
M., et al., Novel Foot-and-Mouth Disease Vaccine
Platform: Formulations for Safe and DIVACompatible FMD Vaccines with Improved Potency.
Frontiers in Veterinary Science, 25 September 2020;
https://doi.org/10.3389/fvets.2020.554305.
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Reviewing Officer’s response to
objections and instructions.
DATES: The effective date of the
Grassland Plan amendment is 30 days
after publication of notice of Grassland
Plan amendment approval in the
newspaper of record, the Laramie
Boomerang.
ADDRESSES: To view the final ROD, final
environmental impact statement (FEIS),
FEIS errata, objection responses, and
other related documents, visit the 2020
Thunder Basin National Grassland Plan
Amendment website at https://
www.fs.usda.gov/project/
?project=55479.
FOR FURTHER INFORMATION CONTACT:
Monique Nelson, plan amendment team
leader, by email at monique.nelson@
usda.gov or by telephone at 307–275–
0956.
Individuals who use
telecommunication devices for the deaf
(TDD) may call the Federal Information
Relay Service (FIRS) at 1–800–877–8339
4 In a 2018 meeting report drafted by the Global
Foot-and-Moth Disease Research Alliance that
reviewed FMD vaccine platforms, the FMDLL3B3D
platform received the highest score. Global Footand-Mouth Disease Research Alliance, Gap
Analysis Report. December 2018: https://
go.usa.gov/xdrKh.
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Federal Register / Vol. 85, No. 232 / Wednesday, December 2, 2020 / Notices
between 8 a.m. and 8 p.m., Eastern
Time, Monday through Friday.
SUPPLEMENTARY INFORMATION: The
Grassland Plan amendment addresses
management of black-tailed prairie dog
colonies on National Forest System land
within the administrative boundary of
the Thunder Basin National Grassland.
New and amended plan components
remove a 56,000-acre ‘‘Black-footed
Ferret Reintroduction Habitat’’
management area and designate a new
42,000-acre ‘‘Short-Stature Vegetation
Emphasis’’ management area; set an
objective of 10,000 acres of prairie dog
colonies for conservation of wildlife
habitat; establish prairie dog
management zones along boundaries
between National Forest System land
and private or state properties; allow
broader application of tools for prairie
dog colony control; and increase
emphasis on management of sylvatic
plague. The Grassland Plan amendment
was informed by the best available
scientific information, current laws and
regulations, and collaborative
relationships with cooperating agencies
and stakeholder groups.
Cooperating Agencies
U.S. Fish and Wildlife Service,
Wyoming Field Office; Natural
Resources Conservation Service,
Wyoming State Office; Wyoming
Department of Agriculture; Wyoming
Game and Fish Department; Wyoming
State Office of Lands and Investments;
Wyoming Weed and Pest Council;
Campbell County, WY; Converse
County, WY; Crook County, WY;
Niobrara County, WY; Weston County,
WY.
Responsible Official
Russell M. Bacon, Forest Supervisor,
Medicine Bow Routt National Forests
and Thunder Basin National Grassland.
Christine Dawe,
Acting Associate Deputy Chief, National
Forest System.
[FR Doc. 2020–26563 Filed 12–1–20; 8:45 am]
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COMMISSION ON CIVIL RIGHTS
Agenda and Notice of Public Meeting
of the Delaware Advisory Committee
Commission on Civil Rights.
Announcement of meetings.
AGENCY:
ACTION:
Notice is hereby given,
pursuant to the provisions of the rules
and regulations of the U.S. Commission
on Civil Rights (Commission), and the
Federal Advisory Committee Act
SUMMARY:
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17:39 Dec 01, 2020
Jkt 253001
(FACA), that planning meetings of the
Delaware Advisory Committee to the
Commission will convene by conference
call, on the following Wednesdays at
1:00 p.m. (ET): November 4 and
December 2, 2020 and January 6 and
February 3, 2021. The purpose of the
meetings is for project planning and
possible selection of project topic and
project proposal.
Wednesdays at 1:00 p.m. (ET),
November 4 and December 2, 2020 and
January 6 and February 3, 2021.
DATES:
Public Call-In Information:
Conference call number: 1–800–367–
2403 and conference call ID: 4195799.
ADDRESSES:
Ivy
L. Davis, at ero@usccr.gov or by phone
at 202–376–7533.
FOR FURTHER INFORMATION CONTACT:
Interested
members of the public may listen to the
discussion by calling the following tollfree conference call number: 1–800–
367–2403 and conference call ID:
4195799. Please be advised that before
placing them into the conference calls,
the conference call operator may ask
callers to provide their names, their
organizational affiliations (if any), and
email addresses (so that callers may be
notified of future meetings). Callers can
expect to incur charges for calls they
initiate over wireless lines, and the
Commission will not refund any
incurred charges. Callers will incur no
charge for calls they initiate over landline connections to the toll-free
telephone number herein.
Individuals who are deaf, deafblind
and hard of hearing may also follow the
proceedings by first calling the Federal
Relay Service at 1–800–877–8339 and
providing the Federal Relay Service
operator with the conference call-in
numbers: 1–800–822–2024 and
conference call ID: 4195799.
Members of the public are invited to
make brief statements during the Public
Comment section of each meeting or to
submit written comments. The
comments must be received in the
regional office approximately 30 days
after each scheduled meeting via email
to Ivy Davis at ero@usccr.gov.
Records and documents discussed
during the meeting will be available for
public viewing, as they become
available, at www.facadatabase.gov.
Persons interested in the work of this
advisory committee are advised to go to
the Commission’s website,
www.usccr.gov, or to contact the Eastern
Regional Office at the above email
address.
SUPPLEMENTARY INFORMATION:
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Agenda
Wednesdays at 1:00 p.m. (ET): Nov. 4
and Dec. 2, 2020 and Jan. 6 and Feb. 3,
2021
I. Welcome and Roll Call
II. Project Planning
III. Other Business
IV. Next Planning Meeting
V. Public Comments
VI. Adjourn
Dated: November 25, 2020.
David Mussatt,
Supervisory Chief, Regional Programs Unit.
[FR Doc. 2020–26553 Filed 12–1–20; 8:45 am]
BILLING CODE 6335–01–P
DEPARTMENT OF COMMERCE
Foreign-Trade Zones Board
[S–174–2020]
Approval of Subzone Expansion;
ASML US, LLC; Wilton, Connecticut
On October 5, 2020, the Executive
Secretary of the Foreign-Trade Zones
(FTZ) Board docketed an application
submitted by the Bridgeport Port
Authority, grantee of FTZ 76, requesting
an expansion of Subzone 76A subject to
the existing activation limit of FTZ 76,
on behalf of ASML US, LLC, in Wilton,
Connecticut.
The application was processed in
accordance with the FTZ Act and
Regulations, including notice in the
Federal Register inviting public
comment (85 FR 63505, October 8,
2020). The FTZ staff examiner reviewed
the application and determined that it
meets the criteria for approval. Pursuant
to the authority delegated to the FTZ
Board Executive Secretary (15 CFR
400.36(f)), the application to expand
Subzone 76A was approved on
November 25, 2020, subject to the FTZ
Act and the Board’s regulations,
including Section 400.13, and further
subject to FTZ 76’s 476-acre activation
limit.
Dated: November 25, 2020.
Andrew McGilvray,
Executive Secretary.
[FR Doc. 2020–26578 Filed 12–1–20; 8:45 am]
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Agencies
[Federal Register Volume 85, Number 232 (Wednesday, December 2, 2020)]
[Notices]
[Pages 77426-77427]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2020-26563]
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DEPARTMENT OF AGRICULTURE
Forest Service
Medicine Bow-Routt National Forests and Thunder Basin National
Grassland; Wyoming; 2020 Thunder Basin National Grassland Plan
Amendment
AGENCY: Forest Service, USDA.
ACTION: Notice of Grassland Plan amendment approval.
-----------------------------------------------------------------------
SUMMARY: Russell M. Bacon, Forest Supervisor for the Medicine Bow-Routt
National Forests and Thunder Basin National Grassland, Rocky Mountain
Region, signed the final Record of Decision (ROD) for the 2020 Thunder
Basin National Grassland Land and Resource Management Plan Amendment
(Grassland Plan amendment). The Final ROD documents the rationale for
approving the Grassland Plan amendment and is consistent with the
Reviewing Officer's response to objections and instructions.
DATES: The effective date of the Grassland Plan amendment is 30 days
after publication of notice of Grassland Plan amendment approval in the
newspaper of record, the Laramie Boomerang.
ADDRESSES: To view the final ROD, final environmental impact statement
(FEIS), FEIS errata, objection responses, and other related documents,
visit the 2020 Thunder Basin National Grassland Plan Amendment website
at https://www.fs.usda.gov/project/?project=55479.
FOR FURTHER INFORMATION CONTACT: Monique Nelson, plan amendment team
leader, by email at [email protected] or by telephone at 307-275-
0956.
Individuals who use telecommunication devices for the deaf (TDD)
may call the Federal Information Relay Service (FIRS) at 1-800-877-8339
[[Page 77427]]
between 8 a.m. and 8 p.m., Eastern Time, Monday through Friday.
SUPPLEMENTARY INFORMATION: The Grassland Plan amendment addresses
management of black-tailed prairie dog colonies on National Forest
System land within the administrative boundary of the Thunder Basin
National Grassland. New and amended plan components remove a 56,000-
acre ``Black-footed Ferret Reintroduction Habitat'' management area and
designate a new 42,000-acre ``Short-Stature Vegetation Emphasis''
management area; set an objective of 10,000 acres of prairie dog
colonies for conservation of wildlife habitat; establish prairie dog
management zones along boundaries between National Forest System land
and private or state properties; allow broader application of tools for
prairie dog colony control; and increase emphasis on management of
sylvatic plague. The Grassland Plan amendment was informed by the best
available scientific information, current laws and regulations, and
collaborative relationships with cooperating agencies and stakeholder
groups.
Cooperating Agencies
U.S. Fish and Wildlife Service, Wyoming Field Office; Natural
Resources Conservation Service, Wyoming State Office; Wyoming
Department of Agriculture; Wyoming Game and Fish Department; Wyoming
State Office of Lands and Investments; Wyoming Weed and Pest Council;
Campbell County, WY; Converse County, WY; Crook County, WY; Niobrara
County, WY; Weston County, WY.
Responsible Official
Russell M. Bacon, Forest Supervisor, Medicine Bow Routt National
Forests and Thunder Basin National Grassland.
Christine Dawe,
Acting Associate Deputy Chief, National Forest System.
[FR Doc. 2020-26563 Filed 12-1-20; 8:45 am]
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