Center for Drug Evaluation and Research's Program for the Recognition of Voluntary Consensus Standards Related to Pharmaceutical Quality; Draft Guidance for Industry; Availability, 4076-4078 [2019-02326]
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4076
Federal Register / Vol. 84, No. 31 / Thursday, February 14, 2019 / Notices
selection of their providers. It also
allows advocacy organizations,
researchers, and other interested parties
access to information on the quality of
care provided to Medicaid beneficiaries
enrolled in Medicaid/CHIP MCOs.
States use the information during their
oversight of these organizations. Form
Number: CMS–R–305 (OMB control
number 0938–0786); Frequency: Yearly;
Affected Public: State, Local, or Tribal
Governments; Number of Respondents:
629; Total Annual Responses: 4,869;
Total Annual Hours: 426,492. (For
policy questions regarding this
collection contact Jennifer Sheer at 410–
786–1769.)
3. Type of Information Collection
Request: Revision of a currently
approved collection; Title of
Information Collection: Report of a
Hospital Death Associated with
Restraint or Seclusion; Use: The final
rule, which finalized the regulations at
42 CFR 482.13(g), published on May, 16,
2012 (77 FR 29074) included a
reduction in the reporting requirements
related to hospital deaths associated
with the use of restraint or seclusion.
Section § 482.13(g) requires that
hospitals must use form CMS–10455 to
report those deaths associated with
restraint and/or seclusion directly to the
Centers for Medicare & Medicaid
Services (CMS) Regional Office (RO).
This requirement also applies to
rehabilitation or psychiatric distinct
part units (DPUs) in Critical Access
Hospitals (CAHs). Currently, the
hospital, CAH, or psychiatric DPU must
submit the form CMS–10455 to the CMS
RO via fax or email, based on RO’s
preference. Beginning on May 9, 2014,
hospitals were no longer required to
report to CMS, those deaths that were
not associated with the use of seclusion
and where the only restraints used were
2-point soft wrist restraints. This
reporting requirement change resulted
in no necessary edits to the form CMS–
10455. It was estimated that this would
reduce the volume of reports that must
be submitted by 90 percent for
hospitals. In addition, the final rule
replaced the previous requirement for
reporting via telephone to CMS, which
proved to be cumbersome for both CMS
and hospitals, with a requirement that
allows the submission of reports on the
form CMS–10455 via facsimile or
electronically, as determined by CMS.
In this PRA package, CMS is seeking
OMB approval for an electronically
submitted version of the currently
approved paper version of form CMS–
10455. Form Number: CMS–10455
(OMB control number: 0938–1210);
Frequency: Occasionally; Affected
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Public: Private Sector; Number of
Respondents: 6,389; Number of
Responses: 6,389; Total Annual Hours:
6,389. (For policy questions regarding
this collection contact Caroline Gallaher
at 410–786–8705.)
4. Type of Information Collection
Request: Revision of a currently
approved collection. Title of
Information Collection: Marketplace
Quality Standards; Use: The Patient
Protection and Affordable Care Act
establishes requirements to support the
delivery of quality health care coverage
for health insurance issuers offering
Qualified Health Plans (QHPs) in
Exchanges. Section 1311(c)(3) of the
Patient Protection and Affordable Care
Act directs the Secretary to develop a
system to rate QHPs on the basis of
quality and price and requires
Exchanges to display this quality rating
information on their respective
websites. Section 1311(c)(4) of the
Patient Protection and Affordable Care
Act requires the Secretary to develop an
enrollee satisfaction survey system to
assess enrollee experience with each
QHP (with more than 500 enrollees in
the previous year) offered through an
Exchange. Section 1311(h) requires
QHPs to contract with certain hospitals
that meet specific patient safety and
health care quality standards.
This collection of information is
necessary to provide adequate and
timely health care quality information
for consumers, regulators, and
Exchanges as well as to collect
information to appropriately monitor
and provide a process for a survey
vendor to appeal HHS’ decision to not
approve a QHP Enrollee Survey vendor
application. Form Number: CMS–10520
(OMB control number: 0938–1249)
Frequency: Annually. Affected Public:
Public sector (Individuals and
Households), Private sector (Business or
other for-profits and Not-for-profit
institutions). Number of Respondents:
264. Total Annual Responses: 264. Total
Annual Hours: 348,764. (For policy
questions regarding this collection
contact Nidhi Singh Shah at 301–492–
5110.)
Dated: February 8, 2019.
William N. Parham, III,
Director, Paperwork Reduction Staff, Office
of Strategic Operations and Regulatory
Affairs.
[FR Doc. 2019–02231 Filed 2–13–19; 8:45 am]
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA–2018–D–4417]
Center for Drug Evaluation and
Research’s Program for the
Recognition of Voluntary Consensus
Standards Related to Pharmaceutical
Quality; Draft Guidance for Industry;
Availability
AGENCY:
Food and Drug Administration,
HHS.
ACTION:
Notice of availability.
The Food and Drug
Administration (FDA or Agency) is
announcing the availability of a draft
guidance for industry entitled ‘‘CDER’s
Program for the Recognition of
Voluntary Consensus Standards Related
to Pharmaceutical Quality.’’ This
guidance describes a proposed program
at FDA’s Center for Drug Evaluation and
Research (CDER) to make public a
comprehensive listing of informally
recognized voluntary consensus
standards related to pharmaceutical
quality. This program, once established,
will facilitate submissions by external
stakeholders and CDER staff proposing
voluntary consensus standards related
to pharmaceutical quality for informal
recognition. CDER believes that this
informal program, which is different
than the formal recognition standards
program in FDA’s Center for Devices
and Radiological Health, will help
promote innovation in pharmaceutical
development and manufacturing and
streamline the compilation and
assessment of marketing applications for
products regulated by CDER. CDER is
issuing this draft guidance to obtain
public comments on the proposed
program.
SUMMARY:
Submit either electronic or
written comments on the draft guidance
by April 15, 2019 to ensure that the
Agency considers your comment on this
draft guidance before it begins work on
the final version of the guidance.
Submit either electronic or written
comments concerning the collection of
information proposed in the draft
guidance by April 15, 2019.
ADDRESSES: You may submit comments
on any guidance at any time as follows:
DATES:
Electronic Submissions
Submit electronic comments in the
following way:
• Federal eRulemaking Portal:
https://www.regulations.gov. Follow the
instructions for submitting comments.
Comments submitted electronically,
E:\FR\FM\14FEN1.SGM
14FEN1
Federal Register / Vol. 84, No. 31 / Thursday, February 14, 2019 / Notices
including attachments, to https://
www.regulations.gov will be posted to
the docket unchanged. Because your
comment will be made public, you are
solely responsible for ensuring that your
comment does not include any
confidential information that you or a
third party may not wish to be posted,
such as medical information, your or
anyone else’s Social Security number, or
confidential business information, such
as a manufacturing process. Please note
that if you include your name, contact
information, or other information that
identifies you in the body of your
comments, that information will be
posted on https://www.regulations.gov.
• If you want to submit a comment
with confidential information that you
do not wish to be made available to the
public, submit the comment as a
written/paper submission and in the
manner detailed (see ‘‘Written/Paper
Submissions’’ and ‘‘Instructions’’).
Written/Paper Submissions
Submit written/paper submissions as
follows:
• Mail/Hand Delivery/Courier (for
written/paper submissions): Dockets
Management Staff (HFA–305), Food and
Drug Administration, 5630 Fishers
Lane, Rm. 1061, Rockville, MD 20852.
• For written/paper comments
submitted to the Dockets Management
Staff, FDA will post your comment, as
well as any attachments, except for
information submitted, marked and
identified, as confidential, if submitted
as detailed in ‘‘Instructions.’’
Instructions: All submissions received
must include the Docket No. FDA–
2018–D–4417 for ‘‘CDER’s Program for
the Recognition of Voluntary Consensus
Standards Related to Pharmaceutical
Quality.’’ Received comments will be
placed in the docket and, except for
those submitted as ‘‘Confidential
Submissions,’’ publicly viewable at
https://www.regulations.gov or at the
Dockets Management Staff office
between 9 a.m. and 4 p.m., Monday
through Friday.
• Confidential Submissions—To
submit a comment with confidential
information that you do not wish to be
made publicly available, submit your
comments only as a written/paper
submission. You should submit two
copies total. One copy will include the
information you claim to be confidential
with a heading or cover note that states
‘‘THIS DOCUMENT CONTAINS
CONFIDENTIAL INFORMATION.’’ The
Agency will review this copy, including
the claimed confidential information, in
its consideration of comments. The
second copy, which will have the
claimed confidential information
VerDate Sep<11>2014
17:54 Feb 13, 2019
Jkt 247001
redacted/blacked out, will be available
for public viewing and posted on
https://www.regulations.gov. Submit
both copies to the Dockets Management
Staff. If you do not wish your name and
contact information to be made publicly
available, you can provide this
information on the cover sheet and not
in the body of your comments and you
must identify this information as
‘‘confidential.’’ Any information marked
as ‘‘confidential’’ will not be disclosed
except in accordance with 21 CFR 10.20
and other applicable disclosure law. For
more information about FDA’s posting
of comments to public dockets, see 80
FR 56469, September 18, 2015, or access
the information at: https://www.gpo.gov/
fdsys/pkg/FR-2015-09-18/pdf/201523389.pdf.
Docket: For access to the docket to
read background documents or the
electronic and written/paper comments
received, go to https://
www.regulations.gov and insert the
docket number, found in brackets in the
heading of this document, into the
‘‘Search’’ box and follow the prompts
and/or go to the Dockets Management
Staff, 5630 Fishers Lane, Rm. 1061,
Rockville, MD 20852.
You may submit comments on any
guidance at any time (see 21 CFR
10.115(g)(5)).
Submit written requests for single
copies of the draft guidance to the
Division of Drug Information, Center for
Drug Evaluation and Research, Food
and Drug Administration, 10001 New
Hampshire Ave., Hillandale Building,
4th Floor, Silver Spring, MD 20993–
0002. Send one self-addressed adhesive
label to assist that office in processing
your requests. See the SUPPLEMENTARY
INFORMATION section for electronic
access to the draft guidance document.
FOR FURTHER INFORMATION CONTACT:
Colleen Thomas, Center for Drug
Evaluation and Research (HFD–003),
Food and Drug Administration, 10903
New Hampshire Ave., Bldg. 51, Rm.
4334, Silver Spring, MD 20993–0002,
301–796–4853.
SUPPLEMENTARY INFORMATION:
I. Background
FDA is announcing the availability of
a draft guidance for industry entitled
‘‘CDER’s Program for the Recognition of
Voluntary Consensus Standards Related
to Pharmaceutical Quality.’’ This
program, once established, will facilitate
submissions by external stakeholders
and CDER staff proposing voluntary
consensus standards related to
pharmaceutical quality for informal
recognition.
The National Technology Transfer
and Advancement Act of 1995 (Pub. L.
PO 00000
Frm 00037
Fmt 4703
Sfmt 4703
4077
104–113) and Circular A–119 by the
Office of Management and Budget
(OMB) have established Federal
Government policies to improve the
internal management of the executive
branch by directing agencies to use
voluntary consensus standards
developed or adopted by a standards
developing organization—rather than
Government-unique standards—except
where these standards are inconsistent
with applicable law or otherwise
impractical. FDA’s development and
use of standards have been integral to
the execution of FDA’s mission.
CDER believes that this informal
program, which is different than the
formal recognition standards program in
FDA’s Center for Devices and
Radiological Health, will help promote
innovation in pharmaceutical
development and manufacturing and
streamline the compilation and review
of marketing applications for products
regulated by CDER. CDER also believes
that this program will: (1) Allow CDER
to communicate to external stakeholders
that its relevant expert(s) have evaluated
a consensus standard and determined if
that standard is potentially useful both
to industry and CDER staff and (2)
provide transparency to industry
regarding CDER’s thinking about a
method or approach.
This draft guidance is being issued
consistent with FDA’s good guidance
practices regulation (21 CFR 10.115).
The draft guidance, when finalized, will
represent the current thinking of FDA
on CDER’s Program for the Recognition
of Voluntary Consensus Standards
Related to Pharmaceutical Quality. It
does not establish any rights for any
person and is not binding on FDA or the
public. You can use an alternative
approach if it satisfies the requirements
of the applicable statutes and
regulations. This guidance is not subject
to Executive Order 12866.
II. Paperwork Reduction Act of 1995
Under the Paperwork Reduction Act
(PRA) (44 U.S.C. 3501–3520), Federal
Agencies must obtain approval from the
OMB for each collection of information
they conduct or sponsor. ‘‘Collection of
information’’ is defined in 44 U.S.C.
3502(3) and 5 CFR 1320.3(c) and
includes Agency requests or
requirements that members of the public
submit reports, keep records, or provide
information to a third party. Section
3506(c)(2)(A) of the PRA (44 U.S.C.
3506(c)(2)(A)) requires Federal Agencies
to provide a 60-day notice in the
Federal Register concerning each
proposed collection of information
before submitting the collection to OMB
for approval. To comply with this
E:\FR\FM\14FEN1.SGM
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Federal Register / Vol. 84, No. 31 / Thursday, February 14, 2019 / Notices
requirement, FDA is publishing notice
of the proposed collection of
information set forth in this document.
With respect to the following
collection of information, FDA invites
comments on these topics: (1) Whether
the proposed collection of information
is necessary for the proper performance
of FDA’s functions, including whether
the information will have practical
utility; (2) the accuracy of FDA’s
estimate of the burden of the proposed
collection of information, including the
validity of the methodology and
assumptions used; (3) ways to enhance
the quality, utility, and clarity of the
information to be collected; and (4)
ways to minimize the burden of the
collection of information on
respondents, including through the use
of automated collection techniques,
when appropriate, and other forms of
information technology.
Request for Recognition of a Voluntary
Consensus Standard
OMB Control Number 0910–NEW
The draft guidance for industry
entitled ‘‘CDER’s Program for the
Recognition of Voluntary Consensus
Standards Related to Pharmaceutical
Quality’’ provides guidance to industry
about the procedures the Center for
Drug Evaluation and Research follows
when a request for recognition of a
voluntary consensus standard is
received. The guidance outlines
justifications for why a standard may be
recognized wholly, partly, or not at all.
The guidance also provides that any
interested party may request recognition
of a standard. Specifically, this process
will allow CDER to:
• Receive a candidate consensus
standard, with relevant information
(e.g., the scope of the standard and the
purpose), from internal or external
parties for informal recognition.
• Determine whether to informally
recognize a standard in whole or in part
following an internal scientific
evaluation.
• List the informally recognized
standards in a publicly searchable
database on CDER’s website,
accompanied by an information sheet
describing the scope and the extent of
CDER’s informal recognition of that
standard and any other relevant
information about it.
Request for Recognition of a Voluntary
Consensus Standard
We estimate that FDA will receive
nine requests annually. We estimate that
each request will take less than 1 hour
to prepare.
FDA estimates the burden of this
collection of information as follows:
TABLE 1—ESTIMATED ANNUAL REPORTING BURDEN 1
Activity
Number of
respondents
Number of
responses per
respondent
Total annual
responses
Average
burden per
response
Total hours
Request for recognition of a voluntary consensus standard
9
1
9
1
9
1 There
are no capital costs or operating and maintenance costs associated with this collection of information.
III. Electronic Access
Persons with access to the internet
may obtain the draft guidance at either
https://www.fda.gov/Drugs/
GuidanceComplianceRegulatory
Information/Guidances/default.htm or
https://www.regulations.gov.
Dated: February 11, 2019.
Lowell J. Schiller,
Acting Associate Commissioner for Policy.
[FR Doc. 2019–02326 Filed 2–13–19; 8:45 am]
BILLING CODE 4164–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Health Resources and Services
Administration
Meeting of the Council on Graduate
Medical Education
Health Resources and Service
Administration (HRSA), Department of
Health and Human Services (HHS).
AGENCY:
ACTION:
Notice.
The Council on Graduate
Medical Education (COGME) has
scheduled a public meeting. Information
about COGME and the agenda for this
meeting can be found on the COGME
website at https://www.hrsa.gov/
SUMMARY:
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17:54 Feb 13, 2019
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advisory-committees/graduate-medicaledu/.
DATES: June 5, 2019, 8:30 a.m.–5:00 p.m.
and June 6, 2019, 8:30 a.m.–2:00 p.m.
ET.
This meeting will be held
in-person and through teleconference
and webinar. The address for the
meeting is 5600 Fishers Lane, Rockville,
Maryland 20857.
• Conference call-in number is: 1–
888–455–0640.
• Passcode is: HRSA COUNCIL (voice
response).
• Webinar link is: https://
hrsa.connectsolutions.com/cogme.
FOR FURTHER INFORMATION CONTACT:
Kennita R. Carter, MD, Designated
Federal Official (DFO), Division of
Medicine and Dentistry, Bureau of
Health Workforce, HRSA, 5600 Fishers
Lane, 15N–116, Rockville, Maryland
20857; 301–945–3505; or KCarter@
hrsa.gov.
ADDRESSES:
COGME
makes recommendations to the
Secretary of HHS (Secretary) and
Congress on policy, program
development, and other matters of
significance as specified by section 762
of Title VII of the Public Health Service
(PHS) Act. Issues addressed by COGME
include (1) the nature and financing of
medical education training; (2) the
SUPPLEMENTARY INFORMATION:
PO 00000
Frm 00038
Fmt 4703
Sfmt 4703
development of performance measures
and longitudinal evaluation methods of
medical education programs; (3) foreign
medical school graduates; (4) the supply
and distribution of the physician
workforce in the United States,
including any projected shortages or
excesses; (5) deficiencies in databases of
the supply and distribution of the
physician workforce and postgraduate
programs for training physicians; and
(6) appropriation levels for certain
programs under Title VII of the PHS
Act. Additionally, COGME encourages
entities providing graduate medical
education to conduct activities to
voluntarily achieve the
recommendations of the council.
COGME submits reports to the Secretary
of HHS, the Senate Committee on
Health, Education, Labor and Pensions,
and the House of Representatives
Committee on Energy and Commerce.
During the June 2019, meeting,
COGME will discuss the topic of rural
health in relation to workforce
development and graduate medical
education financing. Agenda items are
subject to change as priorities dictate.
Refer to the COGME website for any
updated information concerning the
meeting. The meeting agenda will be
available on the COGME website at least
14 calendar days prior to the meeting.
E:\FR\FM\14FEN1.SGM
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Agencies
[Federal Register Volume 84, Number 31 (Thursday, February 14, 2019)]
[Notices]
[Pages 4076-4078]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2019-02326]
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA-2018-D-4417]
Center for Drug Evaluation and Research's Program for the
Recognition of Voluntary Consensus Standards Related to Pharmaceutical
Quality; Draft Guidance for Industry; Availability
AGENCY: Food and Drug Administration, HHS.
ACTION: Notice of availability.
-----------------------------------------------------------------------
SUMMARY: The Food and Drug Administration (FDA or Agency) is announcing
the availability of a draft guidance for industry entitled ``CDER's
Program for the Recognition of Voluntary Consensus Standards Related to
Pharmaceutical Quality.'' This guidance describes a proposed program at
FDA's Center for Drug Evaluation and Research (CDER) to make public a
comprehensive listing of informally recognized voluntary consensus
standards related to pharmaceutical quality. This program, once
established, will facilitate submissions by external stakeholders and
CDER staff proposing voluntary consensus standards related to
pharmaceutical quality for informal recognition. CDER believes that
this informal program, which is different than the formal recognition
standards program in FDA's Center for Devices and Radiological Health,
will help promote innovation in pharmaceutical development and
manufacturing and streamline the compilation and assessment of
marketing applications for products regulated by CDER. CDER is issuing
this draft guidance to obtain public comments on the proposed program.
DATES: Submit either electronic or written comments on the draft
guidance by April 15, 2019 to ensure that the Agency considers your
comment on this draft guidance before it begins work on the final
version of the guidance. Submit either electronic or written comments
concerning the collection of information proposed in the draft guidance
by April 15, 2019.
ADDRESSES: You may submit comments on any guidance at any time as
follows:
Electronic Submissions
Submit electronic comments in the following way:
Federal eRulemaking Portal: https://www.regulations.gov.
Follow the instructions for submitting comments. Comments submitted
electronically,
[[Page 4077]]
including attachments, to https://www.regulations.gov will be posted to
the docket unchanged. Because your comment will be made public, you are
solely responsible for ensuring that your comment does not include any
confidential information that you or a third party may not wish to be
posted, such as medical information, your or anyone else's Social
Security number, or confidential business information, such as a
manufacturing process. Please note that if you include your name,
contact information, or other information that identifies you in the
body of your comments, that information will be posted on https://www.regulations.gov.
If you want to submit a comment with confidential
information that you do not wish to be made available to the public,
submit the comment as a written/paper submission and in the manner
detailed (see ``Written/Paper Submissions'' and ``Instructions'').
Written/Paper Submissions
Submit written/paper submissions as follows:
Mail/Hand Delivery/Courier (for written/paper
submissions): Dockets Management Staff (HFA-305), Food and Drug
Administration, 5630 Fishers Lane, Rm. 1061, Rockville, MD 20852.
For written/paper comments submitted to the Dockets
Management Staff, FDA will post your comment, as well as any
attachments, except for information submitted, marked and identified,
as confidential, if submitted as detailed in ``Instructions.''
Instructions: All submissions received must include the Docket No.
FDA-2018-D-4417 for ``CDER's Program for the Recognition of Voluntary
Consensus Standards Related to Pharmaceutical Quality.'' Received
comments will be placed in the docket and, except for those submitted
as ``Confidential Submissions,'' publicly viewable at https://www.regulations.gov or at the Dockets Management Staff office between 9
a.m. and 4 p.m., Monday through Friday.
Confidential Submissions--To submit a comment with
confidential information that you do not wish to be made publicly
available, submit your comments only as a written/paper submission. You
should submit two copies total. One copy will include the information
you claim to be confidential with a heading or cover note that states
``THIS DOCUMENT CONTAINS CONFIDENTIAL INFORMATION.'' The Agency will
review this copy, including the claimed confidential information, in
its consideration of comments. The second copy, which will have the
claimed confidential information redacted/blacked out, will be
available for public viewing and posted on https://www.regulations.gov.
Submit both copies to the Dockets Management Staff. If you do not wish
your name and contact information to be made publicly available, you
can provide this information on the cover sheet and not in the body of
your comments and you must identify this information as
``confidential.'' Any information marked as ``confidential'' will not
be disclosed except in accordance with 21 CFR 10.20 and other
applicable disclosure law. For more information about FDA's posting of
comments to public dockets, see 80 FR 56469, September 18, 2015, or
access the information at: https://www.gpo.gov/fdsys/pkg/FR-2015-09-18/pdf/2015-23389.pdf.
Docket: For access to the docket to read background documents or
the electronic and written/paper comments received, go to https://www.regulations.gov and insert the docket number, found in brackets in
the heading of this document, into the ``Search'' box and follow the
prompts and/or go to the Dockets Management Staff, 5630 Fishers Lane,
Rm. 1061, Rockville, MD 20852.
You may submit comments on any guidance at any time (see 21 CFR
10.115(g)(5)).
Submit written requests for single copies of the draft guidance to
the Division of Drug Information, Center for Drug Evaluation and
Research, Food and Drug Administration, 10001 New Hampshire Ave.,
Hillandale Building, 4th Floor, Silver Spring, MD 20993-0002. Send one
self-addressed adhesive label to assist that office in processing your
requests. See the SUPPLEMENTARY INFORMATION section for electronic
access to the draft guidance document.
FOR FURTHER INFORMATION CONTACT: Colleen Thomas, Center for Drug
Evaluation and Research (HFD-003), Food and Drug Administration, 10903
New Hampshire Ave., Bldg. 51, Rm. 4334, Silver Spring, MD 20993-0002,
301-796-4853.
SUPPLEMENTARY INFORMATION:
I. Background
FDA is announcing the availability of a draft guidance for industry
entitled ``CDER's Program for the Recognition of Voluntary Consensus
Standards Related to Pharmaceutical Quality.'' This program, once
established, will facilitate submissions by external stakeholders and
CDER staff proposing voluntary consensus standards related to
pharmaceutical quality for informal recognition.
The National Technology Transfer and Advancement Act of 1995 (Pub.
L. 104-113) and Circular A-119 by the Office of Management and Budget
(OMB) have established Federal Government policies to improve the
internal management of the executive branch by directing agencies to
use voluntary consensus standards developed or adopted by a standards
developing organization--rather than Government-unique standards--
except where these standards are inconsistent with applicable law or
otherwise impractical. FDA's development and use of standards have been
integral to the execution of FDA's mission.
CDER believes that this informal program, which is different than
the formal recognition standards program in FDA's Center for Devices
and Radiological Health, will help promote innovation in pharmaceutical
development and manufacturing and streamline the compilation and review
of marketing applications for products regulated by CDER. CDER also
believes that this program will: (1) Allow CDER to communicate to
external stakeholders that its relevant expert(s) have evaluated a
consensus standard and determined if that standard is potentially
useful both to industry and CDER staff and (2) provide transparency to
industry regarding CDER's thinking about a method or approach.
This draft guidance is being issued consistent with FDA's good
guidance practices regulation (21 CFR 10.115). The draft guidance, when
finalized, will represent the current thinking of FDA on CDER's Program
for the Recognition of Voluntary Consensus Standards Related to
Pharmaceutical Quality. It does not establish any rights for any person
and is not binding on FDA or the public. You can use an alternative
approach if it satisfies the requirements of the applicable statutes
and regulations. This guidance is not subject to Executive Order 12866.
II. Paperwork Reduction Act of 1995
Under the Paperwork Reduction Act (PRA) (44 U.S.C. 3501-3520),
Federal Agencies must obtain approval from the OMB for each collection
of information they conduct or sponsor. ``Collection of information''
is defined in 44 U.S.C. 3502(3) and 5 CFR 1320.3(c) and includes Agency
requests or requirements that members of the public submit reports,
keep records, or provide information to a third party. Section
3506(c)(2)(A) of the PRA (44 U.S.C. 3506(c)(2)(A)) requires Federal
Agencies to provide a 60-day notice in the Federal Register concerning
each proposed collection of information before submitting the
collection to OMB for approval. To comply with this
[[Page 4078]]
requirement, FDA is publishing notice of the proposed collection of
information set forth in this document.
With respect to the following collection of information, FDA
invites comments on these topics: (1) Whether the proposed collection
of information is necessary for the proper performance of FDA's
functions, including whether the information will have practical
utility; (2) the accuracy of FDA's estimate of the burden of the
proposed collection of information, including the validity of the
methodology and assumptions used; (3) ways to enhance the quality,
utility, and clarity of the information to be collected; and (4) ways
to minimize the burden of the collection of information on respondents,
including through the use of automated collection techniques, when
appropriate, and other forms of information technology.
Request for Recognition of a Voluntary Consensus Standard
OMB Control Number 0910-NEW
The draft guidance for industry entitled ``CDER's Program for the
Recognition of Voluntary Consensus Standards Related to Pharmaceutical
Quality'' provides guidance to industry about the procedures the Center
for Drug Evaluation and Research follows when a request for recognition
of a voluntary consensus standard is received. The guidance outlines
justifications for why a standard may be recognized wholly, partly, or
not at all. The guidance also provides that any interested party may
request recognition of a standard. Specifically, this process will
allow CDER to:
Receive a candidate consensus standard, with relevant
information (e.g., the scope of the standard and the purpose), from
internal or external parties for informal recognition.
Determine whether to informally recognize a standard in
whole or in part following an internal scientific evaluation.
List the informally recognized standards in a publicly
searchable database on CDER's website, accompanied by an information
sheet describing the scope and the extent of CDER's informal
recognition of that standard and any other relevant information about
it.
Request for Recognition of a Voluntary Consensus Standard
We estimate that FDA will receive nine requests annually. We
estimate that each request will take less than 1 hour to prepare.
FDA estimates the burden of this collection of information as
follows:
Table 1--Estimated Annual Reporting Burden \1\
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Number of
Activity Number of responses per Total annual Average burden Total hours
respondents respondent responses per response
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Request for recognition of a voluntary consensus standard.......... 9 1 9 1 9
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\1\ There are no capital costs or operating and maintenance costs associated with this collection of information.
III. Electronic Access
Persons with access to the internet may obtain the draft guidance
at either https://www.fda.gov/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/default.htm or
https://www.regulations.gov.
Dated: February 11, 2019.
Lowell J. Schiller,
Acting Associate Commissioner for Policy.
[FR Doc. 2019-02326 Filed 2-13-19; 8:45 am]
BILLING CODE 4164-01-P