National Human Genome Research Institute; Notice of Closed Meeting, 51968 [2018-22314]
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51968
Federal Register / Vol. 83, No. 199 / Monday, October 15, 2018 / Notices
commercialization of results of
federally-funded research and
development.
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
FOR FURTHER INFORMATION CONTACT:
National Human Genome Research
Institute; Notice of Closed Meeting
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended, notice is hereby given of a
meeting of the National Human Genome
Research Institute Special Emphasis
Panel.
The meeting will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: National Human
Genome Research Institute Special Emphasis
Panel; Charles Lee Application 2 U24
HG007479–05.
Date: November 9, 2018.
Time: 5:00 p.m. to 6:00 p.m.
Agenda: To review and evaluate grant
applications.
Place: Residence Inn Bethesda Downtown,
7355 Wisconsin Avenue, Room Calvert II,
Bethesda, MD 20814 (Telephone Conference
Call).
Contact Person: Keith McKenney, Ph.D.,
Scientific Review Officer, NHGRI, 5635
Fishers Lane, Suite 4076, Bethesda, MD
20814, 301–594–4280, mckenneyk@
mail.nih.gov.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.172, Human Genome
Research, National Institutes of Health, HHS)
Dated: October 5, 2018.
Sylvia L. Neal,
Program Analyst, Office of Federal Advisory
Committee Policy.
[FR Doc. 2018–22314 Filed 10–12–18; 8:45 am]
BILLING CODE 4140–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
khammond on DSK30JT082PROD with NOTICES
Government-Owned Inventions;
Availability for Licensing
AGENCY:
National Institutes of Health,
HHS.
ACTION:
Notice.
The inventions listed below
are owned by an agency of the U.S.
Government and are available for
licensing to achieve expeditious
SUMMARY:
VerDate Sep<11>2014
21:34 Oct 12, 2018
Jkt 247001
Licensing information may be obtained
by emailing the indicated licensing
contact at the National Heart, Lung, and
Blood, Office of Technology Transfer
and Development Office of Technology
Transfer, 31 Center Drive Room 4A29,
MSC2479, Bethesda, MD 20892–2479;
telephone: 301–402–5579. A signed
Confidential Disclosure Agreement may
be required to receive any unpublished
information.
SUPPLEMENTARY INFORMATION:
Technology description follows.
TSLP for treatment of pulmonary
methicillin-resistant S. aureus (MRSA)
infection. Available for licensing and
commercial development is a patent
estate covering methods of promoting
the host defense of a patient suffering
from or at risk of a bacterial infection
(Methicillin-resistant Staphylococcus
aureus (MRSA) infection in particular)
by administering a thymic stromal
lymphopoeitin (TSLP) protein or
polypeptide. TSLP induces neutrophil
mediated killing of MRSA bacteria
mediated by reactive oxygen species
and complement. Community-acquired
Staphylococcus aureus infections often
present as serious skin infections in
otherwise healthy individuals and have
become a worldwide epidemic fueled by
the emergence of strains with antibiotic
resistance. The cytokine TSLP is highly
expressed in the skin and in other
barrier surfaces and plays a deleterious
role by promoting T helper cell type 2
(TH2) responses during allergic
diseases. The present methodology is
based on a finding of non-TH2’s role for
TSLP in enhancing neutrophil killing of
MRSA during an in vivo skin infection.
TSLP also enhances killing of
Streptococcus pyogenes, another
clinically important cause of human
skin infections. Unexpectedly, TSLP
mechanistically mediates antibacterial
effects by directly engaging the
complement C5 system to modulate
production of reactive oxygen species
by neutrophils.
Potential Commercial Applications:
• MRSA infection.
Inventors: Warren Leonard, Erin West,
Rosanne Spolski (all of NHLBI) and
Christopher Garcia (Stanford).
Relevant Publications:
• J Immunol May 1, 2016, 196 (1
Supplement) 60.5;
• Sci Immunol. 2016 Nov 18;1(5).
Intellectual Property: HHS Reference
No. E–034–2016,
Licensing Contact: Michael
Shmilovich, Esq, CLP; 301–435–5019;
shmilovm@mail.nih.gov.
PO 00000
Frm 00046
Fmt 4703
Sfmt 9990
Dated: September 25, 2018.
Michael A. Shmilovich,
Senior Licensing and Patenting Manager,
National Heart, Lung, and Blood Institute,
Office of Technology Transfer and
Development.
[FR Doc. 2018–22317 Filed 10–12–18; 8:45 am]
BILLING CODE 4140–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
National Institute of Allergy and
Infectious Diseases; Notice of Closed
Meeting
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended, notice is hereby given of the
following meeting.
The meeting will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: National Institute of
Allergy and Infectious Diseases Special
Emphasis Panel Global Infectious Disease
Research Administration Development
Award for Low- and Middle-Income Country
Institutions (G11).
Date: November 6, 2018.
Time: 1:00 p.m. to 3:00 p.m.
Agenda: To review and evaluate grant
applications.
Place: National Institutes of Health, 5601
Fishers Lane, Rockville, MD 20892
(Telephone Conference Call).
Contact Person: Zhuqing (Charlie) Li,
Ph.D., Scientific Review Officer, Scientific
Review Program, Division of Extramural
Activities, Room # 3G41B, National Institutes
of Health/NIAID, 5601 Fishers Lane, MSC
9834, Bethesda, MD 20892–9834, (240) 669–
5068, zhuqing.li@nih.gov.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.855, Allergy, Immunology,
and Transplantation Research; 93.856,
Microbiology and Infectious Diseases
Research, National Institutes of Health, HHS)
Dated: October 5, 2018.
Natasha M. Copeland,
Program Analyst, Office of Federal Advisory
Committee Policy.
[FR Doc. 2018–22313 Filed 10–12–18; 8:45 am]
BILLING CODE 4140–01–P
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[Federal Register Volume 83, Number 199 (Monday, October 15, 2018)]
[Notices]
[Page 51968]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2018-22314]
[[Page 51968]]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health
National Human Genome Research Institute; Notice of Closed
Meeting
Pursuant to section 10(d) of the Federal Advisory Committee Act, as
amended, notice is hereby given of a meeting of the National Human
Genome Research Institute Special Emphasis Panel.
The meeting will be closed to the public in accordance with the
provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5
U.S.C., as amended. The grant applications and the discussions could
disclose confidential trade secrets or commercial property such as
patentable material, and personal information concerning individuals
associated with the grant applications, the disclosure of which would
constitute a clearly unwarranted invasion of personal privacy.
Name of Committee: National Human Genome Research Institute
Special Emphasis Panel; Charles Lee Application 2 U24 HG007479-05.
Date: November 9, 2018.
Time: 5:00 p.m. to 6:00 p.m.
Agenda: To review and evaluate grant applications.
Place: Residence Inn Bethesda Downtown, 7355 Wisconsin Avenue,
Room Calvert II, Bethesda, MD 20814 (Telephone Conference Call).
Contact Person: Keith McKenney, Ph.D., Scientific Review
Officer, NHGRI, 5635 Fishers Lane, Suite 4076, Bethesda, MD 20814,
301-594-4280, [email protected].
(Catalogue of Federal Domestic Assistance Program Nos. 93.172, Human
Genome Research, National Institutes of Health, HHS)
Dated: October 5, 2018.
Sylvia L. Neal,
Program Analyst, Office of Federal Advisory Committee Policy.
[FR Doc. 2018-22314 Filed 10-12-18; 8:45 am]
BILLING CODE 4140-01-P
