National Institute of Neurological Disorders and Stroke; Notice of Closed Meetings, 26070 [2018-11963]
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26070
Federal Register / Vol. 83, No. 108 / Tuesday, June 5, 2018 / Notices
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bsa/bsa.htm, where an agenda and any
additional information for the meeting will
be posted when available.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.392, Cancer Construction;
93.393, Cancer Cause and Prevention
Research; 93.394, Cancer Detection and
Diagnosis Research; 93.395, Cancer
Treatment Research; 93.396, Cancer Biology
Research; 93.397, Cancer Centers Support;
93.398, Cancer Research Manpower; 93.399,
Cancer Control, National Institutes of Health,
HHS)
Dated: May 30, 2018.
Melanie J. Pantoja,
Program Analyst, Office of Federal Advisory
Committee Policy.
[FR Doc. 2018–11958 Filed 6–4–18; 8:45 am]
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National Institutes of Health
National Institute of Neurological
Disorders and Stroke; Notice of Closed
Meetings
amozie on DSK3GDR082PROD with NOTICES1
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended, notice is hereby given of the
following meetings.
The meetings will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: National Institute of
Neurological Disorders and Stroke Special
Emphasis Panel; Summer Research
Education Experience Programs.
Date: June 19, 2018.
Time: 1:00 p.m. to 4:00 p.m.
Agenda: To review and evaluate grant
applications.
Place: National Institutes of Health,
Neuroscience Center, 6001 Executive
20:19 Jun 04, 2018
Jkt 241001
Dated: May 30, 2018.
Sylvia L. Neal,
Program Analyst, Office of Federal Advisory
Committee Policy.
[FR Doc. 2018–11963 Filed 6–4–18; 8:45 am]
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
VerDate Sep<11>2014
Boulevard, Rockville, MD 20852 (Telephone
Conference Call).
Contact Person: Ernest W. Lyons, Ph.D.,
Scientific Review Officer, Scientific Review
Branch, NINDS/NIH/DHHS, Neuroscience
Center, 6001 Executive Blvd, Suite 3208,
MSC 9529, Bethesda, MD 20892–9529, (301)
496–4056, lyonse@ninds.nih.gov.
Name of Committee: National Institute of
Neurological Disorders and Stroke Special
Emphasis Panel; Research Education
Programs for Residents and Fellows.
Date: June 29, 2018.
Time: 11:00 a.m. to 3:00 p.m.
Agenda: To review and evaluate grant
applications.
Place: National Institutes of Health,
Neuroscience Center, 6001 Executive
Boulevard, Rockville, MD 20852 (Telephone
Conference Call).
Contact Person: Ernest W. Lyons, Ph.D.,
Scientific Review Officer, Scientific Review
Branch, NINDS/NIH/DHHS, Neuroscience
Center, 6001 Executive Blvd, Suite 3208,
MSC 9529, Bethesda, MD 20892–9529, (301)
496–4056, lyonse@ninds.nih.gov.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.853, Clinical Research
Related to Neurological Disorders; 93.854,
Biological Basis Research in the
Neurosciences, National Institutes of Health,
HHS)
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
Government-Owned Inventions;
Availability for Licensing
AGENCY:
National Institutes of Health,
HHS.
ACTION:
Notice.
The inventions listed below
are owned by an agency of the U.S.
Government and are available for
licensing in the U.S.
FOR FURTHER INFORMATION CONTACT:
Licensing information and copies of the
patent applications listed below may be
obtained by emailing the indicated
licensing contact at the National Heart,
Lung, and Blood, Office of Technology
Transfer and Development, Office of
Technology Transfer, 31 Center Drive,
Room 4A29, MSC 2479, Bethesda, MD
20892–2479; telephone: 301–402–5579.
A signed Confidential Disclosure
Agreement may be required to receive
copies of the patent applications.
SUPPLEMENTARY INFORMATION: This
notice is in accordance with 35 U.S.C.
209 and 37 CFR part 404 to achieve
SUMMARY:
PO 00000
Frm 00076
Fmt 4703
Sfmt 4703
commercialization of results of
federally-funded research and
development. Foreign patent
applications are filed on selected
inventions to extend market coverage
for companies and may also be available
for licensing. A description of the
technology follows.
Octopod (8-Pointed Star) Iron Oxide
Nanoparticles Enhance MRI T2
Contrast
Description of Technology: The
octopod-shaped iron oxide
nanoparticles of this technology
significantly enhance contrast in MRI
imaging compared to spherical
superparamagnetic iron oxide
nanoparticle T2 contrast agents. These
octopod iron oxide nanoparticles show
a transverse relaxivity that is over five
times greater than comparable spherical
agents. Because the unique octopod
shape creates a greater effective radius
than spherical agents, but maintains
similar magnetization properties, the
relaxation rate is improved. The
improved relaxation rate greatly
enhances the contrast of images. These
octopod agents appear to be biocompatible and may be suitable for
intravenous delivery. The synthesis of
these agents is also easily reproducible
and scaled. The superior contrast greatly
improves diagnostic sensitivities,
compared to current FDA approved
spherical contrast agents. These
octopod-shaped iron oxide nanoparticle
T2 contrast agents may have a number
of medical imaging uses, such as tumor
detection, atherosclerosis imaging and
delivery of therapeutic treatments.
Potential Commercial Applications:
Medical imaging, such as tumor
detection, atherosclerosis imaging and
delivery of therapeutic treatments.
Competitive Advantages:
—Enhanced T2 contrast
—Reproducible and scalable synthesis
—Improved imaging and diagnostic
capability
Development Stage: In vivo data
available (animal).
Inventors: Xiaoyuan Chen (NIBIB),
Jinhao Gao (Xiamen University, China),
Zhenghuan Zhao (Xiamen University,
China).
Publication: Zhao Z, et al. Octapod
iron oxide nanoparticles as highperformance T2 contrast agents for
magnetic resonance imaging. Nat
Commun. 2013;4:2266. [PMID
23903002]
Intellectual Property: HHS Reference
No. E–314–2013/0—PCT Application
No. PCT/CN2013/076645 filed June 3,
2013. Chinese Patent Application
201380077163.3 filed December 3, 2015.
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05JNN1
Agencies
[Federal Register Volume 83, Number 108 (Tuesday, June 5, 2018)]
[Notices]
[Page 26070]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2018-11963]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health
National Institute of Neurological Disorders and Stroke; Notice
of Closed Meetings
Pursuant to section 10(d) of the Federal Advisory Committee Act, as
amended, notice is hereby given of the following meetings.
The meetings will be closed to the public in accordance with the
provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5
U.S.C., as amended. The grant applications and the discussions could
disclose confidential trade secrets or commercial property such as
patentable material, and personal information concerning individuals
associated with the grant applications, the disclosure of which would
constitute a clearly unwarranted invasion of personal privacy.
Name of Committee: National Institute of Neurological Disorders
and Stroke Special Emphasis Panel; Summer Research Education
Experience Programs.
Date: June 19, 2018.
Time: 1:00 p.m. to 4:00 p.m.
Agenda: To review and evaluate grant applications.
Place: National Institutes of Health, Neuroscience Center, 6001
Executive Boulevard, Rockville, MD 20852 (Telephone Conference
Call).
Contact Person: Ernest W. Lyons, Ph.D., Scientific Review
Officer, Scientific Review Branch, NINDS/NIH/DHHS, Neuroscience
Center, 6001 Executive Blvd, Suite 3208, MSC 9529, Bethesda, MD
20892-9529, (301) 496-4056, [email protected].
Name of Committee: National Institute of Neurological Disorders
and Stroke Special Emphasis Panel; Research Education Programs for
Residents and Fellows.
Date: June 29, 2018.
Time: 11:00 a.m. to 3:00 p.m.
Agenda: To review and evaluate grant applications.
Place: National Institutes of Health, Neuroscience Center, 6001
Executive Boulevard, Rockville, MD 20852 (Telephone Conference
Call).
Contact Person: Ernest W. Lyons, Ph.D., Scientific Review
Officer, Scientific Review Branch, NINDS/NIH/DHHS, Neuroscience
Center, 6001 Executive Blvd, Suite 3208, MSC 9529, Bethesda, MD
20892-9529, (301) 496-4056, [email protected].
(Catalogue of Federal Domestic Assistance Program Nos. 93.853,
Clinical Research Related to Neurological Disorders; 93.854,
Biological Basis Research in the Neurosciences, National Institutes
of Health, HHS)
Dated: May 30, 2018.
Sylvia L. Neal,
Program Analyst, Office of Federal Advisory Committee Policy.
[FR Doc. 2018-11963 Filed 6-4-18; 8:45 am]
BILLING CODE 4140-01-P