Availability of Draft Interaction Profile for Mixtures of Insecticides: Pyrethroids, Organophosphorus Compounds, and Carbamates, 22263 [2018-10204]

Download as PDF Federal Register / Vol. 83, No. 93 / Monday, May 14, 2018 / Notices 2. Legacy BancShares, Inc., Springdale, Arkansas; to merge with Gravett Bancshares, Inc., Gravette, Arkansas, and thereby indirectly acquire Bank of Gravett, Gravette, Arkansas. Board of Governors of the Federal Reserve System, May 9, 2018. Yao-Chin Chao, Assistant Secretary of the Board. [FR Doc. 2018–10198 Filed 5–11–18; 8:45 am] BILLING CODE P Dr. Hana Pohl, Division of Toxicology and Human Health Sciences, Agency for Toxic Substances and Disease Registry, 1600 Clifton Rd. NE, MS F–57, Atlanta, GA 30329. Telephone: 770.488.3355. Email: hrp1@cdc.gov. FOR FURTHER INFORMATION CONTACT: DEPARTMENT OF HEALTH AND HUMAN SERVICES Agency for Toxic Substances and Disease Registry [Docket No. ATSDR–2018–0004] Availability of Draft Interaction Profile for Mixtures of Insecticides: Pyrethroids, Organophosphorus Compounds, and Carbamates Agency for Toxic substances and Disease Registry (ATSDR), Department of Health and Human Services (HHS). ACTION: Notice of availability; request for comments. AGENCY: The Agency for Toxic Substances and Disease Registry (ATSDR), within the Department of Health and Human Services (HHS) announces the availability of the Draft Interaction Profile for Mixtures of Insecticides: Pyrethroids, Organophosphorus Compounds, and Carbamates for review and comment. This interaction profile evaluates a mixture of chemicals often found in human blood, adipose tissue, and breast milk. The purpose of this interaction profile is to investigate the possible joint actions of these chemicals on endocrine, developmental, and neurobehavioral endpoints in humans. This interaction profile has undergone external peerreview and review by ATSDR’s Interagency Workgroup on Mixtures. ATSDR remains committed to providing a public comment period for these documents as a means to best serve public health and the public. DATES: Comments must be submitted by August 13, 2018. ADDRESSES: You may submit comments, identified by docket number ATSDR– 2018–0004, by any of the following methods: • Internet: Access the Federal eRulemaking Portal at www.regulations.gov. Follow the instructions for submitting comments. • Mail: Division of Toxicology and Human Health Sciences, Agency for amozie on DSK3GDR082PROD with NOTICES SUMMARY: VerDate Sep<11>2014 18:02 May 11, 2018 Jkt 244001 Toxic Substances and Disease Registry, 1600 Clifton Rd. NE, MS F–57, Atlanta, GA 30329, Attn: Docket ATSDR–2018– 0004. Instructions: All submissions must include the agency name and docket number for this notice. All relevant comments will be posted without change. This means that no confidential business information or other confidential information should be submitted in response to this notice. ATSDR develops interaction profiles for hazardous substances found at the National Priorities List (NPL) sites under Sections 104(i)(3) and (5) of the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA), as amended by the Superfund Amendments and Reauthorization Act of 1986 (SARA). This law requires that ATSDR assess whether or not adequate information on health effects is available for priority hazardous substances. Where such information is not available or under development, ATSDR shall, in cooperation with the National Toxicology Program, initiate a research program to determine these health effects. The Act further directs that, where feasible, ATSDR shall develop methods to determine the health effects of these priority hazardous substances in combination with other substances commonly found with them. To carry out these legislative mandates, ATSDR has created a chemical mixtures program and developed a document, ‘‘Framework for Assessing Health Impacts of Multiple Chemicals and Other Stressors,’’ that outlines the latest methods for mixtures health assessment. The Framework document is available online at https:// www.atsdr.cdc.gov/interactionprofiles/ ipga.html. In addition, a series of documents, called ‘‘interaction profiles,’’ is developed for certain priority mixtures that are of special concern to ATSDR. To recommend approaches for the exposure-based assessment of the potential hazard to public health, an interaction profile evaluates data on the toxicology of the whole priority mixture, if available, and on the joint toxic action of the chemicals in the mixture. SUPPLEMENTARY INFORMATION: PO 00000 Frm 00025 Fmt 4703 Sfmt 4703 22263 Availability The Draft Interaction Profile for Mixtures of Insecticides: Pyrethroids, Organophosphorus Compounds, and Carbamates is available online at https://www.atsdr.cdc.gov/ interactionprofiles/index.asp and at www.regulations.gov, Docket No. ATSDR–2018–0004. Pamela I. Protzel Berman, Director, Office of Policy, Planning and Partnerships, Agency for Toxic Substances and Disease Registry. [FR Doc. 2018–10204 Filed 5–11–18; 8:45 am] BILLING CODE 4163–70–P DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Board of Scientific Counselors, National Center for Injury Prevention and Control, (BSC, NCIPC) Centers for Disease Control and Prevention (CDC), Department of Health and Human Services (HHS). ACTION: Notice of meeting. AGENCY: In accordance with the Federal Advisory Committee Act, the CDC announces the following meeting for the Board of Scientific Counselors, National Center for Injury Prevention and Control, (BSC, NCIPC). This meeting is open to the public limited only by the space and ports available. The meeting room accommodates 70 participants and there will be 125 ports available. Due to the limited accommodations by phone ports and room size, we are encouraging the public to please register using the link provided: Register Here. There will be public comment periods from 11:10 a.m.–11:40 a.m., on June 19, 2018, and from 11:30 a.m.–11:45 a.m., on June 20, 2018. All public comments will be limited to two-minutes per speaker. DATES: The meeting will be held on June 19, 2018, 8:30 a.m.–5:15 p.m., EDT and June 20, 2018, 8:30 a.m.–12:15 p.m., EDT. ADDRESSES: Center for Disease Control and Prevention, Chamblee Campus, 4770 Buford Highway, Building 107, Conference Room 1–A/B, Atlanta, Georgia 30341 and via Teleconference: Dial-In Number: 1–888–769–9404, Participant Code: 5536840. (U.S. & Canada Participants) 1–210–234–0065, Participant Code: 5536840 (International Participants). FOR FURTHER INFORMATION CONTACT: Gwendolyn H. Cattledge, Ph.D., SUMMARY: E:\FR\FM\14MYN1.SGM 14MYN1

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[Federal Register Volume 83, Number 93 (Monday, May 14, 2018)]
[Notices]
[Page 22263]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2018-10204]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Agency for Toxic Substances and Disease Registry

[Docket No. ATSDR-2018-0004]


Availability of Draft Interaction Profile for Mixtures of 
Insecticides: Pyrethroids, Organophosphorus Compounds, and Carbamates

AGENCY: Agency for Toxic substances and Disease Registry (ATSDR), 
Department of Health and Human Services (HHS).

ACTION: Notice of availability; request for comments.

-----------------------------------------------------------------------

SUMMARY: The Agency for Toxic Substances and Disease Registry (ATSDR), 
within the Department of Health and Human Services (HHS) announces the 
availability of the Draft Interaction Profile for Mixtures of 
Insecticides: Pyrethroids, Organophosphorus Compounds, and Carbamates 
for review and comment. This interaction profile evaluates a mixture of 
chemicals often found in human blood, adipose tissue, and breast milk. 
The purpose of this interaction profile is to investigate the possible 
joint actions of these chemicals on endocrine, developmental, and 
neurobehavioral endpoints in humans. This interaction profile has 
undergone external peer-review and review by ATSDR's Interagency 
Workgroup on Mixtures.
    ATSDR remains committed to providing a public comment period for 
these documents as a means to best serve public health and the public.

DATES: Comments must be submitted by August 13, 2018.

ADDRESSES: You may submit comments, identified by docket number ATSDR-
2018-0004, by any of the following methods:
     Internet: Access the Federal eRulemaking Portal at 
www.regulations.gov. Follow the instructions for submitting comments.
     Mail: Division of Toxicology and Human Health Sciences, 
Agency for Toxic Substances and Disease Registry, 1600 Clifton Rd. NE, 
MS F-57, Atlanta, GA 30329, Attn: Docket ATSDR-2018-0004.
    Instructions: All submissions must include the agency name and 
docket number for this notice. All relevant comments will be posted 
without change. This means that no confidential business information or 
other confidential information should be submitted in response to this 
notice.

FOR FURTHER INFORMATION CONTACT: Dr. Hana Pohl, Division of Toxicology 
and Human Health Sciences, Agency for Toxic Substances and Disease 
Registry, 1600 Clifton Rd. NE, MS F-57, Atlanta, GA 30329. Telephone: 
770.488.3355. Email: [email protected].

SUPPLEMENTARY INFORMATION: ATSDR develops interaction profiles for 
hazardous substances found at the National Priorities List (NPL) sites 
under Sections 104(i)(3) and (5) of the Comprehensive Environmental 
Response, Compensation, and Liability Act of 1980 (CERCLA), as amended 
by the Superfund Amendments and Reauthorization Act of 1986 (SARA). 
This law requires that ATSDR assess whether or not adequate information 
on health effects is available for priority hazardous substances. Where 
such information is not available or under development, ATSDR shall, in 
cooperation with the National Toxicology Program, initiate a research 
program to determine these health effects. The Act further directs 
that, where feasible, ATSDR shall develop methods to determine the 
health effects of these priority hazardous substances in combination 
with other substances commonly found with them.
    To carry out these legislative mandates, ATSDR has created a 
chemical mixtures program and developed a document, ``Framework for 
Assessing Health Impacts of Multiple Chemicals and Other Stressors,'' 
that outlines the latest methods for mixtures health assessment. The 
Framework document is available online at https://www.atsdr.cdc.gov/interactionprofiles/ipga.html. In addition, a series of documents, 
called ``interaction profiles,'' is developed for certain priority 
mixtures that are of special concern to ATSDR. To recommend approaches 
for the exposure-based assessment of the potential hazard to public 
health, an interaction profile evaluates data on the toxicology of the 
whole priority mixture, if available, and on the joint toxic action of 
the chemicals in the mixture.

Availability

    The Draft Interaction Profile for Mixtures of Insecticides: 
Pyrethroids, Organophosphorus Compounds, and Carbamates is available 
online at https://www.atsdr.cdc.gov/interactionprofiles/index.asp and 
at www.regulations.gov, Docket No. ATSDR-2018-0004.

Pamela I. Protzel Berman,
Director, Office of Policy, Planning and Partnerships, Agency for Toxic 
Substances and Disease Registry.
[FR Doc. 2018-10204 Filed 5-11-18; 8:45 am]
 BILLING CODE 4163-70-P