National Institute on Aging; Amended Notice of Meeting, 4499-4500 [2018-01823]

Download as PDF Federal Register / Vol. 83, No. 21 / Wednesday, January 31, 2018 / Notices Government and are available for licensing in the U.S. FOR FURTHER INFORMATION CONTACT: Licensing information and copies of the patent applications listed below may be obtained by emailing the indicated licensing contact at the National Heart, Lung, and Blood, Office of Technology Transfer and Development Office of Technology Transfer, 31 Center Drive Room 4A29, MSC2479, Bethesda, MD 20892–2479; telephone: 301–402–5579. A signed Confidential Disclosure Agreement may be required to receive copies of the patent applications. SUPPLEMENTARY INFORMATION: This notice is in accordance with 35 U.S.C. 209 and 37 CFR part 404 to achieve commercialization of results of federally-funded research and development. Foreign patent applications are filed on selected inventions to extend market coverage for companies and may also be available for licensing. A description of the technology follows. sradovich on DSK3GMQ082PROD with NOTICES Chimeric Antibodies Against Hepatitis B e-Antigen Description of Technology: The invention relates to recombinant chimeric rabbit/human monoclonal antibody fragments (Fabs) against hepatitis B Virus e-antigen (HBeAg), notably Fab me6. Viral hepatitis is the seventh leading cause of death worldwide. Hepatitis B core antigen (HBcAg) forms an icosahedral structure containing the viral genome. Both the HBcAg and the HBeAg of interest here are expressed by two different start codons of the viral C gene. Unlike the related HBcAg which activates type 1 T helper (Th1) cells leading to immune attack, the HBeAg activates Th2 cells which promote immune tolerance. The long-term persistence of HBeAg is associated with the development of hepatocellular carcinoma. Conversely, HBeAg seroconversion (from HBeAg carrier to anti-HBeAg carrier) is a marker for successful therapy of chronically infected patients. The presently phage display engineered antibody Fab me6 shows higher sensitivity and selectivity against HBeAg compared to three commercial diagnostics kits tested; additionally, it also inhibits capsid assembly which is essential for viral replication; furthermore, it can also be fully humanized and has potential for antihepatitis B virus therapeutic interventions. Potential Commercial Applications: • Hepatitis B therapy. • Hepatocellular carcinoma prophylaxis. VerDate Sep<11>2014 17:36 Jan 30, 2018 Jkt 244001 Development Stage: • In vitro data available. Inventors: Paul Winfield, Norman Watts, Alasdair Steven (all of NIAMS). Intellectual Property: HHS Reference No. E–192–2017/0–US–01. • U.S. Provisional Patent Application 62/534,603 filed July 19, 2017. Licensing Contact: Michael Shmilovich, Esq, CLP; 301–435–5019; shmilovm@nih.gov. Collaborative Research Opportunity: The National Institute of Environmental Health Sciences seeks statements of capability or interest from parties interested in collaborative research to further develop and evaluate, please contact Cecilia Pazman, Ph.D., Technology Development Specialist, Office of Technology Transfer, National Heart, Lung, and Blood Institute, Phone: (301) 594–4273; pazmance@ nhlbi.nih.gov. Dated: January 25, 2018. Michael Shmilovich, Senior Licensing and Patenting Manager, National Heart, Lung, and Blood Institute, Office of Technology Transfer and Development. [FR Doc. 2018–01928 Filed 1–30–18; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the Skeletal Biology Development and Disease Study Section, February 8, 2018, 8:00 a.m. to February 9, 2018, 3:00 p.m., Westin Baltimore Washington Airport, 1100 Old Elkridge Landing Road, Linthicum Heights, MD, 21090 which was published in the Federal Register on January 5, 2018, 83 FR PG 683. The meeting will be held on February 7, 2018 at 3:00 p.m. and end February 8, 2018 at 9:00 p.m. The meeting location remains the same. The meeting is closed to the public. Dated: January 25, 2018. Melanie J. Pantoja, Program Analyst, Office of Federal Advisory Committee Policy. [FR Doc. 2018–01821 Filed 1–30–18; 8:45 am] BILLING CODE 4140–01–P PO 00000 Frm 00037 Fmt 4703 Sfmt 4703 4499 DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Heart, Lung, and Blood Institute; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended, notice is hereby given of a meeting of the NHLBI Mentored Transition to Independence Review Committee. The meeting will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: Heart, Lung, and Blood Initial Review Group; NHLBI Mentored Transition to Independence Review Committee. Date: March 8–9, 2018. Time: 8:00 a.m. to 1:00 p.m. Agenda: To review and evaluate grant applications. Place: The William F. Bolger Center, 9600 Newbridge Drive, Potomac, MD 20854. Contact Person: Giuseppe Pintucci, Ph.D., Scientific Review Officer, Office of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701 Rockledge Drive, Room 7192, Bethesda, MD 20892, 301–435–0287, Pintuccig@nhlbi.nih.gov. (Catalogue of Federal Domestic Assistance Program Nos. 93.233, National Center for Sleep Disorders Research; 93.837, Heart and Vascular Diseases Research; 93.838, Lung Diseases Research; 93.839, Blood Diseases and Resources Research, National Institutes of Health, HHS) Dated: January 26, 2018. Michelle Trout, Program Analyst, Office of Federal Advisory Committee Policy. [FR Doc. 2018–01930 Filed 1–30–18; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Advisory Council on Aging, January 23, 2018, 3:00 p.m. to January 24, 2018, 2:00 p.m., National Institutes of Health, Building E:\FR\FM\31JAN1.SGM 31JAN1 4500 Federal Register / Vol. 83, No. 21 / Wednesday, January 31, 2018 / Notices 31, C Wing 6th Floor Conference Room 10, 9000 Rockville Pike, Bethesda, MD, 20892 which was published in the Federal Register on December 11, 2017, 82 FR 58212. Because of the strong possibility that the government would be shut down during the scheduled council date, rescheduling would have been very difficult due to the very tight timing of initiatives whose concepts were expected to be approved at January council. NIA had arranged for Notices of their availability to be published by early February for April 17 deadline (for FY 2018 award). The institute made the decision to hold an abbreviated council via teleconference on Friday January 19th, prior to the midnight deadline to keep the government open. They were counseled to post this information on their IC website. The meeting is closed to the public. Dated: January 25, 2018. Melanie J. Pantoja, Program Analyst, Office of Federal Advisory Committee Policy. [FR Doc. 2018–01823 Filed 1–30–18; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the Psychosocial Risk and Disease Prevention Study Section, January 22, 2018, 08:00 a.m. to January 23, 2018, 06:00 p.m., Embassy Suites at the Chevy Chase Pavilion, 4300 Military Road NW, Washington, DC 20015 which was published in the Federal Register on December 21, 2017, V–82 Pg. 60614. The meeting will be held on February 27, 2018, 8:00 a.m. to February 28, 2018, 6:00 p.m. at Hyatt Regency Bethesda, One Metro Center, Bethesda, MD 20814. The meeting is closed to the public. sradovich on DSK3GMQ082PROD with NOTICES Dated: January 26, 2018. Sylvia L. Neal, Program Analyst, Office of Federal Advisory Committee Policy. [FR Doc. 2018–01926 Filed 1–30–18; 8:45 am] BILLING CODE 4140–01–P VerDate Sep<11>2014 17:36 Jan 30, 2018 Jkt 244001 DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of General Medical Sciences; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended, notice is hereby given of the following meetings. The meetings will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: National Institute of General Medical Sciences Special Emphasis Panel; To review COBRE Phase II. Date: March 9, 2018. Time: 8:00 a.m. to 5:00 p.m. Agenda: To review and evaluate grant applications. Place: Doubletree by Hilton Bethesda, 8120 Wisconsin Avenue, Bethesda, MD 20814. Contact Person: Nina Sidorova, Ph.D., Scientific Review Officer, Office of Scientific Review, National Institute of General Medical Sciences, National Institutes of Health, 45 Center Drive, Room 3An.22, Bethesda, MD 20892–6200, 301–594–3663, sidorova@ nigms.nih.gov. Name of Committee: National Institute of General Medical Sciences Special Emphasis Panel; Review of ESI MIRA Applications. Date: March 15–16, 2018. Time: 8:00 a.m. to 5:00 p.m. Agenda: To review and evaluate grant applications. Place: Hilton Garden Inn Bethesda, 7301 Waverly Street, Bethesda, MD 20814. Contact Person: Saraswathy Seetharam, Ph.D., Scientific Review Officer, Office Scientific Review, National Institute of General Medical Sciences, National Institutes Health, 45 Center Drive, Room 3AN12C, Bethesda, MD 20892, 301–594–2763, seetharams@nigms.nih.gov. (Catalogue of Federal Domestic Assistance Program Nos. 93.375, Minority Biomedical Research Support; 93.821, Cell Biology and Biophysics Research; 93.859, Pharmacology, Physiology, and Biological Chemistry Research; 93.862, Genetics and Developmental Biology Research; 93.88, Minority Access to Research Careers; 93.96, Special Minority Initiatives; 93.859, Biomedical Research and Research Training, National Institutes of Health, HHS) PO 00000 Frm 00038 Fmt 4703 Sfmt 4703 Dated: January 25, 2018. Melanie J. Pantoja, Program Analyst, Office of Federal Advisory Committee Policy. [FR Doc. 2018–01825 Filed 1–30–18; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the Center for Scientific Review Special Emphasis Panel, January 23, 2018, 08:00 a.m. to January 23, 2018, 03:00 p.m., Embassy Suites at the Chevy Chase Pavilion, 4300 Military Road NW, Washington, DC 20015 which was published in the Federal Register on December 26, 2017, V–82 Pg. 61017. The meeting will be held on February 28, 2018, 8:00 a.m.–12:00 p.m. at Hyatt Regency Bethesda, One Metro Center, Bethesda, MD 20814. The meeting is closed to the public. Dated: January 26, 2018. Sylvia L. Neal, Program Analyst, Office of Federal Advisory Committee Policy. [FR Doc. 2018–01927 Filed 1–30–18; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Nursing Research; Notice to Close Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended, notice is hereby given of the following meeting. The meeting will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: National Institute of Nursing Research Initial Review Group. Date: February 15–16, 2018. Time: 8:00 a.m. to 12:00 p.m. Agenda: To review and evaluate grant applications. E:\FR\FM\31JAN1.SGM 31JAN1

Agencies

[Federal Register Volume 83, Number 21 (Wednesday, January 31, 2018)]
[Notices]
[Pages 4499-4500]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2018-01823]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


National Institute on Aging; Amended Notice of Meeting

    Notice is hereby given of a change in the meeting of the National 
Advisory Council on Aging, January 23, 2018, 3:00 p.m. to January 24, 
2018, 2:00 p.m., National Institutes of Health, Building

[[Page 4500]]

31, C Wing 6th Floor Conference Room 10, 9000 Rockville Pike, Bethesda, 
MD, 20892 which was published in the Federal Register on December 11, 
2017, 82 FR 58212.
    Because of the strong possibility that the government would be shut 
down during the scheduled council date, rescheduling would have been 
very difficult due to the very tight timing of initiatives whose 
concepts were expected to be approved at January council. NIA had 
arranged for Notices of their availability to be published by early 
February for April 17 deadline (for FY 2018 award). The institute made 
the decision to hold an abbreviated council via teleconference on 
Friday January 19th, prior to the midnight deadline to keep the 
government open. They were counseled to post this information on their 
IC website. The meeting is closed to the public.

    Dated: January 25, 2018.
Melanie J. Pantoja,
Program Analyst, Office of Federal Advisory Committee Policy.
[FR Doc. 2018-01823 Filed 1-30-18; 8:45 am]
 BILLING CODE 4140-01-P
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