Government-Owned Inventions; Availability for Licensing, 10779-10780 [2017-03016]

Download as PDF Federal Register / Vol. 82, No. 30 / Wednesday, February 15, 2017 / Notices mstockstill on DSK3G9T082PROD with NOTICES licensing to achieve expeditious commercialization of results of federally-funded research and development. Foreign patent applications are filed on selected inventions to extend market coverage for companies and may also be available for licensing. FOR FURTHER INFORMATION CONTACT: Licensing information and copies of the patent applications listed below may be obtained by communicating with the indicated licensing contact at the Technology Transfer and Intellectual Property Office, National Institute of Allergy and Infectious Diseases, 5601 Fishers Lane, Rockville, MD 20852; tel. 301–496–2644. A signed Confidential Disclosure Agreement will be required to receive copies of unpublished patent applications. SUPPLEMENTARY INFORMATION: Technology description follows. Synergistic Internal Ribosomal Entry Site (IRES)—MicroRNA-Based Approach for Attenuation of Flaviviruses and Live Vaccine Development Description of Technology: Many members of the Flaviviridae family are emerging and reemerging human pathogens that have caused outbreaks of devastating and often fatal diseases and represent a serious public health problem on a global scale. There is no single attenuation strategy that exists which is sufficient to prepare a safe, efficacious and immunogenic live attenuated virus vaccine that will work universally for Flaviviridae. This patent application claims live attenuated flavivirus vaccines, live attenuated multivalent flavivirus vaccines, and methods of preventing flavivirus infections as well as methods of making the vaccines claimed in the application. More specifically, this patent application claims methods for attenuating a flavivirus or chimeric flavivirus using a synergistic dual strategy involving inserting miRNAtargeting sequences to restrict virus replication in target hosts, cells and/or tissues and placing one or more flavivirus genes under translational control of an internal ribosomal entry site (IRES). This technology is available for licensing for commercial development in accordance with 35 U.S.C. 209 and 37 CFR part 404, as well as for further development and evaluation under a research collaboration. Potential Commercial Applications: • Diagnostics • Vaccines Competitive Advantages: VerDate Sep<11>2014 18:44 Feb 14, 2017 Jkt 241001 • • • • Potential one-dose flavivirus vaccine Ease of manufacture in Vero cells Low-cost potential vaccine Developing and developed world potential vaccines Development Stage: • In vivo data available (animal) Inventors: Alexander Pletnev (NIAID), Konstantin Tsetsarkin (NIAID). Intellectual Property: HHS Reference No. E–006–2017/0—U.S. Provisional Application No. 62/443,214, filed January 6, 2017. Licensing Contact: Peter Soukas, J.D., 301–594–8730; peter.soukas@nih.gov. Collaborative Research Opportunity: The National Institute of Allergy and Infectious Diseases is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate or commercialize vaccine(s) for prophylaxis against flavivirus infections. For collaboration opportunities, please contact Peter Soukas, J.D., 301–594–8730; peter.soukas@nih.gov. Dated: February 6, 2017. Suzanne Frisbie, Deputy Director, Technology Transfer and Intellectual Property Office, National Institute of Allergy and Infectious Diseases. [FR Doc. 2017–03017 Filed 2–14–17; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Government-Owned Inventions; Availability for Licensing AGENCY: National Institutes of Health, HHS. ACTION: Notice. The invention listed below is owned by an agency of the U.S. Government and is available for licensing to achieve expeditious commercialization of results of federally-funded research and development. Foreign patent applications are filed on selected inventions to extend market coverage for companies and may also be available for licensing. FOR FURTHER INFORMATION CONTACT: Licensing information and copies of the patent applications listed below may be obtained by communicating with the indicated licensing contact at the Technology Transfer and Intellectual Property Office, National Institute of Allergy and Infectious Diseases, 5601 Fishers Lane, Rockville, MD 20852; tel. SUMMARY: PO 00000 Frm 00046 Fmt 4703 Sfmt 4703 10779 301–496–2644. A signed Confidential Disclosure Agreement will be required to receive copies of unpublished patent applications. SUPPLEMENTARY INFORMATION: Technology description follows. A Bivalent Conjugate Vaccine for Malaria and Typhoid Prophylaxis Description of Technology: Malaria is the single leading cause of mortality, especially among children in the developing world. Typhoid fever, caused by infection with Salmonella typhi, is known to be endemic with malaria and causes its own significant disease burden. Scientists at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have developed a novel bivalent vaccine candidate that may effectively prevent malaria and typhoid. This approach significantly enhances immune response to the Pfs25 Malaria transmission blocking antigen and produces a robust immune response against Salmonella typhi Vi polysaccharide (ViP). This technology is available for licensing for commercial development in accordance with 35 U.S.C. 209 and 37 CFR part 404, as well as for further development and evaluation under a research collaboration. Potential Commercial Applications: • Development of this technology into a vaccine may protect vulnerable populations from both Malaria transmission and Typhoid fever. Competitive Advantages: • This technology has significant advantages over current treatments, since there is currently only one commercial Malaria vaccine licensed for use in Europe only, which was not developed to address Malaria transmission, and the currently licensed Salmonella typhi vaccines show incomplete efficacy and do not provide long-term immunity. A formulation of the present technology has shown the ability to induce an immune response to Pfs25 in excess of 100 times higher and Salmonella typhi antigen 20–40 times higher than what is seen by immunization with either antigen alone. Development Stage: • In vivo data available (animal). Inventors: Drs. Patrick Duffy, Sojung An, and Puthupparampil Scaria, NIAID, NIH. Publications: None. Intellectual Property: Provisional Patent application #62/327,184 Filed 04/25/16, Technology reference #E– 124–2016/0. E:\FR\FM\15FEN1.SGM 15FEN1 10780 Federal Register / Vol. 82, No. 30 / Wednesday, February 15, 2017 / Notices Licensing Contact: Daniel Anacker, Ph.D., 301–761–7671, daniel.anacker@ nih.gov. Collaborative Research Opportunity: The NIAID, Laboratory of Malaria Immunology and Vaccinology is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize this technology. Please contact Dr. Daniel Anacker at 301–761– 7671 or daniel.anacker@nih.gov for more information. Dated: February 8, 2017. Suzanne Frisbie, Deputy Director, Technology Transfer and Intellectual Property Office, National Institute of Allergy and Infectious Diseases. [FR Doc. 2017–03016 Filed 2–14–17; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HOMELAND SECURITY [Docket No. DHS–2017–0005] The President’s National Security Telecommunications Advisory Committee Department of Homeland Security. ACTION: Committee Management; Notice of Federal Advisory Committee Meeting. AGENCY: The President’s National Security Telecommunications Advisory Committee (NSTAC) will meet via teleconference on Friday, March 3, 2017. The meeting will be open to the public. DATES: The NSTAC will meet on Friday, March 3, 2017, from 12:00 p.m. to 1:00 p.m. Eastern Standard Time (EST). Please note that the meeting may close early if the committee has completed its business. ADDRESSES: The meeting will be held via conference call. For access to the conference call bridge, information on services for individuals with disabilities, or to request special assistance to attend, please email NSTAC@hq.dhs.gov by 5:00 p.m. EST on Monday, February 27, 2017. Members of the public are invited to provide comment on the issues that will be considered by the committee as listed in the SUPPLEMENTARY INFORMATION section below. Associated briefing materials that participants may discuss during the meeting will be available at www.dhs.gov/nstac for review as of Friday, February 24, 2017. Comments may be submitted at any time and must be identified by docket number DHS– 2017–0005. Comments may be mstockstill on DSK3G9T082PROD with NOTICES SUMMARY: VerDate Sep<11>2014 18:44 Feb 14, 2017 Jkt 241001 submitted by one of the following methods: • Federal eRulemaking Portal: https:// www.regulations.gov. Please follow the instructions for submitting written comments. • Email: NSTAC@hq.dhs.gov. Include the docket number DHS–2017–0005 in the subject line of the email. • Fax: (703) 235–5962, ATTN: Sandy Benevides. • Mail: Designated Federal Officer, Stakeholder Engagement and Critical Infrastructure Resilience Division, National Protection and Programs Directorate, Department of Homeland Security, 245 Murray Lane, Mail Stop 0604, Arlington, VA 20598–0604. Instructions: All submissions received must include the words ‘‘Department of Homeland Security’’ and the docket number for this action. Comments received will be posted without alteration at www.regulations.gov, including any personal information provided. Docket: For access to the docket and comments received by the NSTAC, please go to www.regulations.gov and enter docket number DHS–2017–0005. A public comment period will be held during the conference call on Friday, March 3, 2017, from 12:40 p.m. to 12:55 p.m. EST. Speakers who wish to participate in the public comment period must register in advance and can do so by emailing NSTAC@hq.dhs.gov no later than Monday, February 27, 2017, at 5:00 p.m. EST. Speakers are requested to limit their comments to three minutes and will speak in order of registration. Please note that the public comment period may end before the time indicated, following the last request for comments. FOR FURTHER INFORMATION CONTACT: Helen Jackson, NSTAC Designated Federal Officer, Department of Homeland Security, (703) 235–5321 (telephone) or helen.jackson@ hq.dhs.gov (email). SUPPLEMENTARY INFORMATION: Notice of this meeting is given under the Federal Advisory Committee Act, 5 U.S.C. appendix (Pub. L. 92–463). The NSTAC advises the President on matters related to national security and emergency preparedness (NS/EP) telecommunications and cybersecurity policy. Agenda: The NSTAC will hold a conference call on March 3, 2017, to discuss issues and challenges related to NS/EP communications, which will include discussions with high-level Government stakeholders and a review of ongoing NSTAC work, including an update on the NSTAC Emerging PO 00000 Frm 00047 Fmt 4703 Sfmt 4703 Technologies Strategic Vision Subcommittee’s study of the near- and longer-term NS/EP implications of emergent and expected information and communications technologies. Dated: February 2, 2017. Helen Jackson, Designated Federal Officer for the NSTAC. [FR Doc. 2017–03009 Filed 2–14–17; 8:45 am] BILLING CODE 9110–9P–P INTERNATIONAL BOUNDARY AND WATER COMMISSION UNITED STATES AND MEXICO United States Section; Notice of Availability of a Final Environmental Assessment and Finding of No Significant Impact for Alamito and Terneros Sediment and Vegetation Removal Below Presidio Flood Control Project, Presidio, Texas United States Section, International Boundary and Water Commission, United States and Mexico. ACTION: Notice of Availability of the Final Environmental Assessment (EA) and Finding of No Significant Impact (FONSI). AGENCY: Pursuant to Section 102(2)(c) of the National Environmental Policy Act of 1969; the Council on Environmental Quality Final Regulations (40 CFR parts 1500 through 1508); and the United States Section, Operational Procedures for Implementing Section 102 of NEPA, published in the Federal Register September 2, 1981 (46 FR 44083); the United States Section hereby gives notice that the Final Environmental Assessment and Finding of No Significant Impact (FONSI) for Alamito and Terneros Sediment and Vegetation Removal below Presidio Flood Control Project, Presidio, Texas is available. An environmental impact statement will not be prepared unless additional information which may affect this decision is brought to our attention within 30-days from the date of this Notice. FOR FURTHER INFORMATION CONTACT: Gilbert Anaya, Division Chief, Environmental Management Division; United States Section, International Boundary and Water Commission; 4171 N. Mesa, C–100, El Paso, Texas 79902. Telephone: (915) 832–4702, email: Gilbert.Anaya@ibwc.gov. Background: This Final Environmental Assessment analyzes the potential impacts of removing accumulated sediment from Alamito and Terneros Creeks at their confluence SUMMARY: E:\FR\FM\15FEN1.SGM 15FEN1

Agencies

[Federal Register Volume 82, Number 30 (Wednesday, February 15, 2017)]
[Notices]
[Pages 10779-10780]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2017-03016]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Government-Owned Inventions; Availability for Licensing

AGENCY: National Institutes of Health, HHS.

ACTION: Notice.

-----------------------------------------------------------------------

SUMMARY: The invention listed below is owned by an agency of the U.S. 
Government and is available for licensing to achieve expeditious 
commercialization of results of federally-funded research and 
development. Foreign patent applications are filed on selected 
inventions to extend market coverage for companies and may also be 
available for licensing.

FOR FURTHER INFORMATION CONTACT: Licensing information and copies of 
the patent applications listed below may be obtained by communicating 
with the indicated licensing contact at the Technology Transfer and 
Intellectual Property Office, National Institute of Allergy and 
Infectious Diseases, 5601 Fishers Lane, Rockville, MD 20852; tel. 301-
496-2644. A signed Confidential Disclosure Agreement will be required 
to receive copies of unpublished patent applications.

SUPPLEMENTARY INFORMATION: Technology description follows.

A Bivalent Conjugate Vaccine for Malaria and Typhoid Prophylaxis

    Description of Technology: Malaria is the single leading cause of 
mortality, especially among children in the developing world. Typhoid 
fever, caused by infection with Salmonella typhi, is known to be 
endemic with malaria and causes its own significant disease burden. 
Scientists at the National Institute of Allergy and Infectious Diseases 
(NIAID), part of the National Institutes of Health, have developed a 
novel bivalent vaccine candidate that may effectively prevent malaria 
and typhoid. This approach significantly enhances immune response to 
the Pfs25 Malaria transmission blocking antigen and produces a robust 
immune response against Salmonella typhi Vi polysaccharide (ViP).
    This technology is available for licensing for commercial 
development in accordance with 35 U.S.C. 209 and 37 CFR part 404, as 
well as for further development and evaluation under a research 
collaboration.
    Potential Commercial Applications:
     Development of this technology into a vaccine may protect 
vulnerable populations from both Malaria transmission and Typhoid 
fever.
    Competitive Advantages:
     This technology has significant advantages over current 
treatments, since there is currently only one commercial Malaria 
vaccine licensed for use in Europe only, which was not developed to 
address Malaria transmission, and the currently licensed Salmonella 
typhi vaccines show incomplete efficacy and do not provide long-term 
immunity. A formulation of the present technology has shown the ability 
to induce an immune response to Pfs25 in excess of 100 times higher and 
Salmonella typhi antigen 20-40 times higher than what is seen by 
immunization with either antigen alone.
    Development Stage:
     In vivo data available (animal).
    Inventors: Drs. Patrick Duffy, Sojung An, and Puthupparampil 
Scaria, NIAID, NIH.
    Publications: None.
    Intellectual Property: Provisional Patent application #62/327,184 
Filed 04/25/16, Technology reference #E-124-2016/0.

[[Page 10780]]

    Licensing Contact: Daniel Anacker, Ph.D., 301-761-7671, 
daniel.anacker@nih.gov.
    Collaborative Research Opportunity: The NIAID, Laboratory of 
Malaria Immunology and Vaccinology is seeking statements of capability 
or interest from parties interested in collaborative research to 
further develop, evaluate, or commercialize this technology. Please 
contact Dr. Daniel Anacker at 301-761-7671 or daniel.anacker@nih.gov 
for more information.

    Dated: February 8, 2017.
Suzanne Frisbie,
Deputy Director, Technology Transfer and Intellectual Property Office, 
National Institute of Allergy and Infectious Diseases.
[FR Doc. 2017-03016 Filed 2-14-17; 8:45 am]
BILLING CODE 4140-01-P
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