Government-Owned Inventions; Availability for Licensing, 4366 [2017-00735]

Download as PDF asabaliauskas on DSK3SPTVN1PROD with NOTICES 4366 Federal Register / Vol. 82, No. 9 / Friday, January 13, 2017 / Notices NIH_Guidelines.html), these experiments can proceed only after they are reviewed by the NIH Recombinant DNA Advisory Committee (RAC) and specifically approved by the NIH Director as Major Actions. This proposal was discussed at the December 4, 2015, RAC meeting. The proposal was published in the Federal Register on December 29, 2015, (80 FR 81346) with a request for public comment; one comment was received. This notice announces the final NIH action regarding this proposal. FOR FURTHER INFORMATION CONTACT: If you have questions, or require additional background information about this action, please contact the NIH by email at SciencePolicy@od.nih.gov, or by telephone at 301–496–9838 and reference this notice. SUPPLEMENTARY INFORMATION: This final action does not allow an investigator at the University of Chicago to transfer chloramphenicol resistance to three different Rickettsia species: Rickettsia typhi, rickettsii, and felis. The investigator also proposed to transfer chloramphenicol resistance to a fourth Rickettsia species, R. conorii. Transfer of chloramphenicol resistance to R. conorii was previously approved by the NIH Director as a Major Action (see 73 FR 32719) and therefore did not need to be reviewed and approved under Section III–A–1–a of the NIH Guidelines. Thus, the University of Chicago investigator was allowed to proceed with the transfer of chloramphenicol resistance to R. conorii under Section III–B–2 of the NIH Guidelines. The proposal to transfer chloramphenicol resistance to R. typhi, rickettsii, and felis was discussed with a working group of the RAC via a teleconference call on October 22, 2015. The recommendations of this group were presented to and discussed with the RAC at its December 4, 2015, meeting. At the March 8, 2016, meeting, the RAC continued the discussion which included consideration of the one comment received to the December 29, 2015, notice and unanimously recommended (by a vote of 11 in favor, none opposed, and no abstentions) that the transfer of chloramphenicol resistance to R. typhi, rickettsii, and felis should not be allowed to proceed. On August 23, 2016, the NIH Director disapproved the proposal to transfer chloramphenicol resistance to R. typhi, rickettsii, and felis. Dated: January 6, 2017. Francis S. Collins, Director, National Institutes of Health. [FR Doc. 2017–00766 Filed 1–12–17; 8:45 am] BILLING CODE 4140–01–P VerDate Sep<11>2014 19:06 Jan 12, 2017 Jkt 241001 DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Government-Owned Inventions; Availability for Licensing AGENCY: National Institutes of Health, HHS. ACTION: Notice. The invention listed below is owned by an agency of the U.S. Government and is available for licensing to achieve expeditious commercialization of results of federally-funded research and development. Foreign patent applications are filed on selected inventions to extend market coverage for companies and may also be available for licensing. FOR FURTHER INFORMATION CONTACT: Licensing information and copies of the patent applications listed below may be obtained by communicating with the indicated licensing contact at the Technology Transfer and Intellectual Property Office, National Institute of Allergy and Infectious Diseases, 5601 Fishers Lane, Rockville, MD 20852; tel. 301–496–2644. A signed Confidential Disclosure Agreement will be required to receive copies of unpublished patent applications. SUPPLEMENTARY INFORMATION: Technology description follows. SUMMARY: Monoclonal Antibodies That Neutralize Norovirus Description of Technology: Vaccines and therapies to prevent and treat Norovirus infections do not exist, despite the worldwide prevalence of Norovirus infections. Outbreaks of human gastroenteritis attributable to Norovirus commonly occur in group setting, such as hospitals, nursing homes, schools, dormitories, cruise ships and military barracks. This technology relates to chimpanzeehuman chimeric monoclonal antibodies, which specifically bind to Norovirus and have therapeutic potential. The antibodies that were tested in a primate model of infection have shown protection against Norovirus. These Norovirus antibodies may have application as immunoprophylaxis to protect individuals from infections or as a possible treatment for infected individuals, or can be used to develop a diagnostic for detection of norovirus infections. This technology is available for licensing for commercial development in accordance with 35 U.S.C. 209 and 37 CFR part 404, as well as for further PO 00000 Frm 00088 Fmt 4703 Sfmt 4703 development and evaluation under a research collaboration. Potential Commercial Applications: • Therapeutics • Diagnostics Competitive Advantages: • There are currently no vaccines or therapeutics available against Norovirus infections Development Stage: • In vivo data available (animal) Inventors: Zhaochun Chen, Robert H. Purcell, Lisbeth Kim Green, Stanislav Sosnovtsev, Karin Bok (all from NIAID). Publications: Chen Z, et al., Development of Norwalk virus-specific monoclonal antibodies with therapeutic potential for the treatment of Norwalk virus gastroenteritis, J Virol. 2013 Sep; 87(17):9547–57. [PMID 23785216]. Intellectual Property: HHS Reference No. E–226–2011/0—U.S. Provisional Application No. 61/763,879, filed February 12, 2013; PCT Application No. PCT/US2014/015809, filed February 11, 2014; European Application No. 14706239.2, filed August 5, 2015 (pending); U.S. Application No. 14/ 767,274, filed August 11, 2015 (allowed); and U.S. Application No. 15/ 359,438, filed November 22, 2016 (pending). Licensing Contact: Dr. Jenish Patel, 240–669–2894; Jenish.Patel@nih.gov. Collaborative Research Opportunity: The National Institute of Allergy and Infectious Diseases is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate or commercialize for development of a therapeutic or a diagnostic for Norovirus infections. For collaboration opportunities, please contact Dr. Jenish Patel, 240–669–2894; Jenish.Patel@ nih.gov. Dated: January 9, 2017. Suzanne Frisbie, Deputy Director, Technology Transfer and Intellectual Property Office, National Institute of Allergy and Infectious Diseases. [FR Doc. 2017–00735 Filed 1–12–17; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is hereby given of the following meetings. E:\FR\FM\13JAN1.SGM 13JAN1

Agencies

[Federal Register Volume 82, Number 9 (Friday, January 13, 2017)]
[Notices]
[Page 4366]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2017-00735]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Government-Owned Inventions; Availability for Licensing

AGENCY: National Institutes of Health, HHS.

ACTION: Notice.

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SUMMARY: The invention listed below is owned by an agency of the U.S. 
Government and is available for licensing to achieve expeditious 
commercialization of results of federally-funded research and 
development. Foreign patent applications are filed on selected 
inventions to extend market coverage for companies and may also be 
available for licensing.

FOR FURTHER INFORMATION CONTACT: Licensing information and copies of 
the patent applications listed below may be obtained by communicating 
with the indicated licensing contact at the Technology Transfer and 
Intellectual Property Office, National Institute of Allergy and 
Infectious Diseases, 5601 Fishers Lane, Rockville, MD 20852; tel. 301-
496-2644. A signed Confidential Disclosure Agreement will be required 
to receive copies of unpublished patent applications.

SUPPLEMENTARY INFORMATION: Technology description follows.

Monoclonal Antibodies That Neutralize Norovirus

    Description of Technology: Vaccines and therapies to prevent and 
treat Norovirus infections do not exist, despite the worldwide 
prevalence of Norovirus infections. Outbreaks of human gastroenteritis 
attributable to Norovirus commonly occur in group setting, such as 
hospitals, nursing homes, schools, dormitories, cruise ships and 
military barracks. This technology relates to chimpanzee-human chimeric 
monoclonal antibodies, which specifically bind to Norovirus and have 
therapeutic potential. The antibodies that were tested in a primate 
model of infection have shown protection against Norovirus. These 
Norovirus antibodies may have application as immunoprophylaxis to 
protect individuals from infections or as a possible treatment for 
infected individuals, or can be used to develop a diagnostic for 
detection of norovirus infections.
    This technology is available for licensing for commercial 
development in accordance with 35 U.S.C. 209 and 37 CFR part 404, as 
well as for further development and evaluation under a research 
collaboration.
    Potential Commercial Applications:

 Therapeutics
 Diagnostics

    Competitive Advantages:

 There are currently no vaccines or therapeutics available 
against Norovirus infections

    Development Stage:

 In vivo data available (animal)

    Inventors: Zhaochun Chen, Robert H. Purcell, Lisbeth Kim Green, 
Stanislav Sosnovtsev, Karin Bok (all from NIAID).
    Publications: Chen Z, et al., Development of Norwalk virus-specific 
monoclonal antibodies with therapeutic potential for the treatment of 
Norwalk virus gastroenteritis, J Virol. 2013 Sep; 87(17):9547-57. [PMID 
23785216].
    Intellectual Property: HHS Reference No. E-226-2011/0--U.S. 
Provisional Application No. 61/763,879, filed February 12, 2013; PCT 
Application No. PCT/US2014/015809, filed February 11, 2014; European 
Application No. 14706239.2, filed August 5, 2015 (pending); U.S. 
Application No. 14/767,274, filed August 11, 2015 (allowed); and U.S. 
Application No. 15/359,438, filed November 22, 2016 (pending).
    Licensing Contact: Dr. Jenish Patel, 240-669-2894; 
Jenish.Patel@nih.gov.
    Collaborative Research Opportunity: The National Institute of 
Allergy and Infectious Diseases is seeking statements of capability or 
interest from parties interested in collaborative research to further 
develop, evaluate or commercialize for development of a therapeutic or 
a diagnostic for Norovirus infections. For collaboration opportunities, 
please contact Dr. Jenish Patel, 240-669-2894; Jenish.Patel@nih.gov.

    Dated: January 9, 2017.
Suzanne Frisbie,
Deputy Director, Technology Transfer and Intellectual Property Office, 
National Institute of Allergy and Infectious Diseases.
[FR Doc. 2017-00735 Filed 1-12-17; 8:45 am]
 BILLING CODE 4140-01-P