Nominations to the National Toxicology Program for the Report on Carcinogens and Office of Health Assessment and Translation; Request for Information, 62513-62514 [2016-21698]
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62513
Federal Register / Vol. 81, No. 175 / Friday, September 9, 2016 / Notices
Officer at paperwork@hrsa.gov or call
(301) 443–1984.
SUPPLEMENTARY INFORMATION:
Information Collection Request Title:
Small Rural Hospital Transitions Project
OMB No. 0906–xxxx—NEW
Abstract: Under Section 330A of the
Public Health Service Act (42 U.S.C.
254c(e)), the Federal Office of Rural
Health Policy (FORHP) funds grant
programs supporting expanding access
to, and improving the quality of
essential health care services in rural
and frontier communities. Small rural
hospitals are facing many challenges in
the new health care environment,
including the concurrent need to better
measure and account for quality of care
in all settings; improving transitions of
care as patients move from one care
setting to another; adopting new
payment approaches such as valuebased purchasing; and tailoring
operations to the new approaches to
care delivery, such as accountable care
organizations (ACO) and patientcentered medical homes. Success in this
new environment will require bridging
the gaps between the current system and
the newly emerging system of
healthcare delivery and payment.
Because little is known about how these
new models might impact rural
communities, there is a need to help
hospitals understand and consider those
factors that would make them logical
participants in health care systems that
focus on value. The Small Rural
Hospital Transitions (SRHT) Project will
assist small rural hospitals in making
the transition. The purpose of the
project is to provide on-site technical
assistance to nine small rural hospitals
located in persistent poverty counties.
Technical assistance will be provided in
the areas of: (1) Financial assessments,
(2) creating a quality-focused
environment, (3) aligning services to
community need, and, (4) to the extent
that financial and quality core areas
have been stabilized, assistance to help
the hospitals consider factors that
would make them logical participants in
health care systems that focus on value
(for example ACOs, shared savings
programs, primary care medical homes).
Need and Proposed Use of the
Information: The information will be
solicited in the form of the SRHT Project
Technical Assistance Online
Application form and the supporting
hospital assessment, Performance
Excellence for Rural Hospitals. All small
rural hospitals desiring to apply for
onsite technical assistance through
SRHT will be required to complete the
application and the survey. The
applicant’s information will be scored
and ranked to aid in the selection of
nine small rural hospitals to receive onsite technical assistance. Both the
application form and the hospital
assessment are designed to ensure the
selection of hospital applicants
consistent with established eligibility
criteria and hospitals readiness or
ability to implement consultant’s
recommendations.
A 60-day Federal Register Notice was
published in the Federal Register on
June 24, 2016 (81 FR 41315). There were
no public comments.
Likely Respondents: Small rural
hospitals located in a rural community,
as defined by FORHP, persistent poverty
county, or a rural census tract of a metro
persistent poverty county; have 49
staffed beds or less as reported on the
hospital’s most recently filed Medicare
Cost Report. Hospitals; and for-profit or
not-for-profit.
Burden Statement: Burden in this
context means the time expended by
persons to generate, maintain, retain,
disclose or provide the information
requested. This includes the time
needed to review instructions; to
develop, acquire, install and utilize
technology and systems for the purpose
of collecting, validating and verifying
information, processing and
maintaining information, and disclosing
and providing information; to train
personnel and to be able to respond to
a collection of information; to search
data sources; to complete and review
the collection of information; and to
transmit or otherwise disclose the
information. The total annual burden
hours estimated for this ICR are
summarized in the table below.
TOTAL ESTIMATED ANNUALIZED BURDEN—HOURS
Number of
respondents
Form name
Number of
responses
per
respondent
Average
burden per
response
(in hours)
Total
responses
Total burden
hours
SRHT Project Technical Assistance Online Application .....
Assessment: Performance Excellence for Rural Hospitals
30
30
38
29
1140
870
.50
.25
570
217.5
Total ..............................................................................
* 30
........................
2010
........................
787.5
* The same individuals complete the SRHT Online Application and the Assessment for a total of 30 respondents.
Jason E. Bennett,
Director, Division of the Executive Secretariat.
[FR Doc. 2016–21733 Filed 9–8–16; 8:45 am]
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
Nominations to the National
Toxicology Program for the Report on
Carcinogens and Office of Health
Assessment and Translation; Request
for Information
The National Toxicology
Program (NTP) requests information on
four nominations. Four substances are
being considered for possible review for
future editions of the Report on
Carcinogens (RoC). Three of these four
substances are also being considered for
SUMMARY:
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evaluation of non-cancer health
outcomes by the Office of Health
Assessment and Translation (OHAT).
DATES: Receipt of information: Deadline
is October 11, 2016.
ADDRESSES: Information on substances
for possible review should be submitted
electronically at https://
ntp.niehs.nih.gov/go/778417.
FOR FURTHER INFORMATION CONTACT:
RoC Nominations: Dr. Ruth Lunn,
Director, Office of RoC; telephone (919)
316–4637; lunn@niehs.nih.gov. OHAT
Nominations: Dr. Windy Boyd, OHAT,
telephone (919) 541–9810; boydw@
niehs.nih.gov. Address for Dr. Lunn and
Dr. Boyd: Division of NTP, National
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asabaliauskas on DSK3SPTVN1PROD with NOTICES
62514
Federal Register / Vol. 81, No. 175 / Friday, September 9, 2016 / Notices
Institute of Environmental Health
Sciences, 111 T.W. Alexander Drive,
P.O. Box 12233, Research Triangle Park,
NC 27709.
SUPPLEMENTARY INFORMATION:
Request for Information: NTP requests
information on four substances that
have been nominated for possible
review for future editions of the RoC
(see https://ntp.niehs.nih.gov/go/
rocnom); three of these four substances
are also under consideration for
evaluation of non-cancer health
outcomes (see https://ntp.niehs.nih.gov/
go/763346). The four nominations are:
• Consumption of red meat: cancer
and non-cancer health hazard
evaluations.
• Consumption of processed meat:
cancer and non-cancer health hazard
evaluations.
• Consumption of meat cooked at
high temperatures: cancer and noncancer health hazard evaluations.
• Antimony trioxide: cancer hazard
evaluation.
Cancer hazard evaluation of a
substance for the RoC may seek to list
a new substance in the report, reclassify
the listing status of a substance already
listed, or remove a listed substance.
Specifically, NTP requests
information on: (1) Current production,
use patterns, and human exposure
estimates for antimony trioxide; (2) data
on dietary intake estimates of red meat,
processed meat, or meat cooked at high
temperatures; and for all four
nominations (3) recently published,
ongoing, or planned studies related to
evaluating adverse health outcomes
(e.g., cancer, development,
reproductive, or immunological
disorders); (4) scientific issues
important for prioritizing and assessing
adverse health outcomes; and (5) names
of scientists with expertise or
knowledge on any of these substances—
please indicate the substance and
include any bibliographic citations
when available. NTP will use this
information in determining which
substances to propose for formal health
hazard evaluations.
Information on substances for
possible review should be submitted
electronically at https://
ntp.niehs.nih.gov/go/778417 or emailed
to Dr. Lunn or Dr. Boyd (see FOR
FURTHER INFORMATION CONTACT). Contact
information for comments should
include the submitter’s name,
affiliation, sponsoring organization (if
any), telephone, and email. Written
information received in response to this
notice will be posted on the NTP Web
site, and the submitter identified by
name, affiliation, and/or sponsoring
VerDate Sep<11>2014
17:11 Sep 08, 2016
Jkt 238001
organization. Guidelines for public
comments are at https://
ntp.niehs.nih.gov/ntp/about_ntp/
guidelines_public_comments_508.pdf.
Responses to this request for
information are voluntary. This request
for information is for planning purposes
only and is not a solicitation for
applications or an obligation on the part
of the U.S. Government to provide
support for any ideas identified in
response to it. Please note that the U.S.
Government will not pay for the
preparation of any information
submitted or for its use. No proprietary,
classified, confidential, or sensitive
information should be included in your
response.
Background Information on ORoC: On
behalf of NTP, ORoC prepares the RoC
following an established, four-part
process (https://ntp.niehs.nih.gov/go/
rocprocess). The RoC is a
congressionally mandated, sciencebased, public health report that
identifies agents, substances, mixtures,
or exposures (collectively called
‘‘substances’’) in our environment that
pose a cancer hazard for people in the
United States. Published biennially,
each edition of the RoC is cumulative
and consists of substances newly
reviewed in addition to those listed in
previous editions. Newly reviewed
substances with their recommended
listing are reviewed and approved by
the Secretary of Health and Human
Services. The 13th RoC, the latest
edition, was published on October 2,
2014 (available at https://
ntp.niehs.nih.gov/go/roc13). The 14th
RoC is under development.
Background Information on OHAT:
On behalf of NTP, OHAT conducts
literature-based evaluations to assess the
evidence whether environmental
chemicals, physical substances, or
mixtures (collectively called
‘‘substances’’) cause adverse non-cancer
health outcomes. As part of these
evaluations, NTP may also provide
opinions on whether these substances
might be of concern for causing adverse
effects on human health given what is
known about toxicity and current
human exposure levels. Information
about OHAT can be found at https://
ntp.niehs.nih.gov/go/ohat.
Dated: September 6, 2016.
John R. Bucher,
Associate Director, National Toxicology
Program.
[FR Doc. 2016–21698 Filed 9–8–16; 8:45 am]
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
Government-Owned Inventions;
Availability for Licensing
AGENCY:
National Institutes of Health,
HHS.
ACTION:
Notice.
The inventions listed below
are owned by an agency of the U.S.
Government and are available for
licensing in the U.S. in accordance with
35 U.S.C. 209 and 37 CFR part 404 to
achieve expeditious commercialization
of results of federally-funded research
and development.
FOR FURTHER INFORMATION CONTACT:
Licensing information may be obtained
by emailing the indicated licensing
contact at the National Heart, Lung, and
Blood, Office of Technology Transfer
and Development Office of Technology
Transfer, 31 Center Drive, Room 4A29,
MSC2479, Bethesda, MD 20892–2479;
telephone: 301–402–5579. A signed
Confidential Disclosure Agreement may
be required to receive any unpublished
information.
SUPPLEMENTARY INFORMATION:
Technology description follows.
SUMMARY:
Reagent for Mapping Genome-Wide
Enhancer-Promoter Interactions
This invention is a research reagent
named the ‘‘bivalent Tn5 complex’’
used in transposition-mediated analysis
of chromatin looping (TrAC-looping) to
determine genome-wide enhancerpromoter interactions during studies of
4D nucleomes in normal development
and disease conditions. Enhancerpromoter interactions are key in
temporospatial control of gene
expression during normal development
and pathological conditions. Currently
available methods of analyzing genomewide enhancer-promoter interactions
are insufficient in achieving necessary
resolution, give rise to false positive
artifacts due to in vitro ligation steps, or
too expensive due to the necessity of
sequencing over a billion reads. The
instant reagent and associated TrAClooping technique effectively reduce
false positive detection and achieve a 10
to 100-times higher resolution at lower
cost for mapping genome-wide
interactions between enhancers and
promotes essential for the control of
gene expression in normal development
and pathological conditions.
References
—Lieberman-Aiden E et al., Science
2009 Oct 9;326(5950):289–93.
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Agencies
[Federal Register Volume 81, Number 175 (Friday, September 9, 2016)]
[Notices]
[Pages 62513-62514]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2016-21698]
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health
Nominations to the National Toxicology Program for the Report on
Carcinogens and Office of Health Assessment and Translation; Request
for Information
SUMMARY: The National Toxicology Program (NTP) requests information on
four nominations. Four substances are being considered for possible
review for future editions of the Report on Carcinogens (RoC). Three of
these four substances are also being considered for evaluation of non-
cancer health outcomes by the Office of Health Assessment and
Translation (OHAT).
DATES: Receipt of information: Deadline is October 11, 2016.
ADDRESSES: Information on substances for possible review should be
submitted electronically at https://ntp.niehs.nih.gov/go/778417.
FOR FURTHER INFORMATION CONTACT:
RoC Nominations: Dr. Ruth Lunn, Director, Office of RoC; telephone
(919) 316-4637; lunn@niehs.nih.gov. OHAT Nominations: Dr. Windy Boyd,
OHAT, telephone (919) 541-9810; boydw@niehs.nih.gov. Address for Dr.
Lunn and Dr. Boyd: Division of NTP, National
[[Page 62514]]
Institute of Environmental Health Sciences, 111 T.W. Alexander Drive,
P.O. Box 12233, Research Triangle Park, NC 27709.
SUPPLEMENTARY INFORMATION:
Request for Information: NTP requests information on four
substances that have been nominated for possible review for future
editions of the RoC (see https://ntp.niehs.nih.gov/go/rocnom); three of
these four substances are also under consideration for evaluation of
non-cancer health outcomes (see https://ntp.niehs.nih.gov/go/763346).
The four nominations are:
Consumption of red meat: cancer and non-cancer health
hazard evaluations.
Consumption of processed meat: cancer and non-cancer
health hazard evaluations.
Consumption of meat cooked at high temperatures: cancer
and non-cancer health hazard evaluations.
Antimony trioxide: cancer hazard evaluation.
Cancer hazard evaluation of a substance for the RoC may seek to
list a new substance in the report, reclassify the listing status of a
substance already listed, or remove a listed substance.
Specifically, NTP requests information on: (1) Current production,
use patterns, and human exposure estimates for antimony trioxide; (2)
data on dietary intake estimates of red meat, processed meat, or meat
cooked at high temperatures; and for all four nominations (3) recently
published, ongoing, or planned studies related to evaluating adverse
health outcomes (e.g., cancer, development, reproductive, or
immunological disorders); (4) scientific issues important for
prioritizing and assessing adverse health outcomes; and (5) names of
scientists with expertise or knowledge on any of these substances--
please indicate the substance and include any bibliographic citations
when available. NTP will use this information in determining which
substances to propose for formal health hazard evaluations.
Information on substances for possible review should be submitted
electronically at https://ntp.niehs.nih.gov/go/778417 or emailed to Dr.
Lunn or Dr. Boyd (see FOR FURTHER INFORMATION CONTACT). Contact
information for comments should include the submitter's name,
affiliation, sponsoring organization (if any), telephone, and email.
Written information received in response to this notice will be posted
on the NTP Web site, and the submitter identified by name, affiliation,
and/or sponsoring organization. Guidelines for public comments are at
https://ntp.niehs.nih.gov/ntp/about_ntp/guidelines_public_comments_508.pdf.
Responses to this request for information are voluntary. This
request for information is for planning purposes only and is not a
solicitation for applications or an obligation on the part of the U.S.
Government to provide support for any ideas identified in response to
it. Please note that the U.S. Government will not pay for the
preparation of any information submitted or for its use. No
proprietary, classified, confidential, or sensitive information should
be included in your response.
Background Information on ORoC: On behalf of NTP, ORoC prepares the
RoC following an established, four-part process (https://ntp.niehs.nih.gov/go/rocprocess). The RoC is a congressionally
mandated, science-based, public health report that identifies agents,
substances, mixtures, or exposures (collectively called ``substances'')
in our environment that pose a cancer hazard for people in the United
States. Published biennially, each edition of the RoC is cumulative and
consists of substances newly reviewed in addition to those listed in
previous editions. Newly reviewed substances with their recommended
listing are reviewed and approved by the Secretary of Health and Human
Services. The 13th RoC, the latest edition, was published on October 2,
2014 (available at https://ntp.niehs.nih.gov/go/roc13). The 14th RoC is
under development.
Background Information on OHAT: On behalf of NTP, OHAT conducts
literature-based evaluations to assess the evidence whether
environmental chemicals, physical substances, or mixtures (collectively
called ``substances'') cause adverse non-cancer health outcomes. As
part of these evaluations, NTP may also provide opinions on whether
these substances might be of concern for causing adverse effects on
human health given what is known about toxicity and current human
exposure levels. Information about OHAT can be found at https://ntp.niehs.nih.gov/go/ohat.
Dated: September 6, 2016.
John R. Bucher,
Associate Director, National Toxicology Program.
[FR Doc. 2016-21698 Filed 9-8-16; 8:45 am]
BILLING CODE 4140-01-P