Findings of Research Misconduct, 59642-59643 [2016-20834]

Download as PDF 59642 Federal Register / Vol. 81, No. 168 / Tuesday, August 30, 2016 / Notices technology and systems for the purpose of collecting, validating and verifying information; (3) processing and maintaining information; (4) disclosing and providing information; (5) training personnel to be able to respond to a collection of information; (6) searching Burden Statement: Burden in this context means the time expended by persons to generate, maintain, retain, disclose or provide the information requested. This includes (1) the time needed to review instructions; (2) to develop, acquire, install and utilize data sources; (7) completing and reviewing the collection of information; and (8) transmitting or otherwise disclosing the information. The total annual burden hours estimated for this ICR are summarized in the table below. TOTAL ESTIMATED ANNUALIZED BURDEN—HOURS Number of respondents Form name Number of responses per respondent Total responses Average burden per response (in hours) Total burden hours Baseline Pre-TED (Transplant Essential Data) ................... Product Form (includes Infusion, HLA, and Infectious Disease Marker inserts) ........................................................ 100-Day Post-TED ............................................................... 6-Month Post-TED ............................................................... 12-Month Post-TED ............................................................. Annual Post-TED ................................................................. 200 44 8,800 1.15 10,120 200 200 200 200 200 33 44 36 32 110 6,600 8,800 7,200 6,400 22,000 1 1.25 1.15 1.15 1.15 6,600 11,000 8,280 7,360 25,300 * Total ............................................................................ 200 ........................ 59,800 ........................ 68,660 * The Total of 200 is the number of centers completing the form. The same group of 200 centers completes each of the forms. Jason E. Bennett, Director, Division of the Executive Secretariat. [FR Doc. 2016–20758 Filed 8–29–16; 8:45 am] BILLING CODE 4165–15–P DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary Findings of Research Misconduct Office of the Secretary, HHS. Notice. AGENCY: ACTION: Notice is hereby given that the Office of Research Integrity (ORI) has taken final action in the following case: Andrew R. Cullinane, Ph.D., National Institutes of Health: Based on Respondent’s admission, an assessment conducted by the National Institutes of Health (NIH), and analysis conducted by ORI in its oversight review, ORI found that Dr. Andrew R. Cullinane, former postdoctoral fellow, Medical Genetics Branch, National Human Genome Research Institute (NHGRI), NIH, engaged in research misconduct in research supported by NHGRI, NIH. ORI found that Respondent engaged in research misconduct by reporting falsified and/or fabricated data in the following two (2) publications and one (1) submitted manuscript: • Am. J. Hum. Genet. 88(6):778–787, 2011 (hereafter referred to as ‘‘Paper 1’’) • Neurology 86(14):1320–1328, 2016 (hereafter referred to as ‘‘Paper 2’’) • ‘‘RAB11FIP1, Mutated in HPS–10, Interacts with BLOC–1 to Mitigate mstockstill on DSK3G9T082PROD with NOTICES SUMMARY: VerDate Sep<11>2014 20:04 Aug 29, 2016 Jkt 238001 Recycling of Melanogenic Proteins.’’ Submitted for publication to The Journal of Clinical Investigations, Cell, Nature Biology, Molecular Cell, and Nature Genetics (hereafter referred to as ‘‘Manuscript 1’’) ORI found that Respondent knowingly falsified and/or fabricated data and related images by alteration and/or reuse and/or relabeling of experimental data. Specifically: • in Paper 1, Respondent falsified and/ or fabricated the results in Figure 3C by using the same gel images to represent expression of PLDN in fibroblasts and melanocytes • in Paper 2, Respondent falsified and/ or fabricated the results in Figure 2A by erasure of a band in the blot image for LYST/CHD–4 that was present in the original data • in Manuscript 1, Respondent falsified and/or fabricated the results in Western blot data by reuse and relabeling, duplication, and/or manipulation in Figures 2B, 2D, 2E, 3A–C, 4C, 4E, 4G, 5B, 6A–C, 7A, 7D, 7G, 7J, and Supplemental Figure 3, and Respondent falsified and/or fabricated the results by reuse and relabeling of centrifuge tubes to represent different experiments in Figures 1D, 7C, 7F, 7I, 7L, and Supplemental Figure 2 Dr. Cullinane has entered into a Voluntary Settlement Agreement with ORI and NIH, in which he voluntarily agreed: (1) To have his research supervised for a period of three (3) years beginning on July 22, 2016; Respondent agreed to ensure that prior to the submission of an application for U.S. Public Health PO 00000 Frm 00046 Fmt 4703 Sfmt 4703 Service (PHS) support for a research project on which Respondent’s participation is proposed and prior to Respondent’s participation in any capacity on PHS-supported research, the institution employing him must submit a plan for supervision of his duties to ORI for approval. The plan for supervision must be designed to ensure the scientific integrity of Respondent’s research contribution; Respondent agreed that he will not participate in any PHS-supported research until a plan for supervision is submitted to and approved by ORI; Respondent agreed to maintain responsibility for compliance with the agreed upon supervision plan; (2) that for a period of three (3) years beginning on July 22, 2016, any institution employing him shall submit, in conjunction with each application for PHS funds, or report, manuscript, or abstract involving PHS-supported research in which Respondent is involved, a certification to ORI that the data provided by Respondent are based on actual experiments or are otherwise legitimately derived and that the data, procedures, and methodology are accurately reported in the application, report, manuscript, or abstract; (3) to exclude himself from serving in any advisory capacity to PHS including, but not limited to, service on any PHS advisory committee, board, and/or peer review committee, or as a consultant for a period of three (3) years, beginning on July 22, 2016; and (4) as a condition of the Agreement, Respondent agreed to the retraction or correction of: • Am. J. Hum. Genet. 88(6):778–787, 2011 E:\FR\FM\30AUN1.SGM 30AUN1 Federal Register / Vol. 81, No. 168 / Tuesday, August 30, 2016 / Notices • Neurology 86(14):1320–1328, 2016 FOR FURTHER INFORMATION CONTACT: Director, Office of Research Integrity, 1101 Wootton Parkway, Suite 750, Rockville, MD 20852, (240) 453–8200. Kathryn M. Partin, Director, Office of Research Integrity. [FR Doc. 2016–20834 Filed 8–29–16; 8:45 am] BILLING CODE 4150–31–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Notice of Diabetes Mellitus Interagency Coordinating Committee Meeting The Diabetes Mellitus Interagency Coordinating Committee (DMICC) will hold a meeting on September 12, 2016. The subject of the meeting will be the ‘‘Diabetes and Neurocognition.’’ The meeting is open to the public. DATES: The meeting will be held on September 12, 2016; from 1:00 p.m. to 4:30 p.m. Individuals wanting to present oral comments must notify the contact person at least 10 days before the meeting date. ADDRESSES: The meeting will be held in the Democracy 2 Building at 6707 Democracy Blvd., Bethesda, MD, in Conference Room 7050. FOR FURTHER INFORMATION CONTACT: For further information concerning this meeting, see the DMICC Web site, www.diabetescommittee.gov, or contact Dr. B. Tibor Roberts, Executive Secretary of the Diabetes Mellitus Interagency Coordinating Committee, National Institute of Diabetes and Digestive and Kidney Diseases, 31 Center Drive, Building 31A, Room 9A19, MSC 2560, Bethesda, MD 20892– 2560, telephone: 301–496–6623; FAX: 301–480–6741; email: dmicc@ mail.nih.gov. SUPPLEMENTARY INFORMATION: The DMICC, chaired by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) comprising members of the Department of Health and Human Services and other federal agencies that support diabetes-related activities, facilitates cooperation, communication, and collaboration on diabetes among government entities. DMICC meetings, held several times a year, provide an opportunity for Committee members to learn about and discuss current and future diabetes programs in DMICC member organizations and to identify opportunities for collaboration. The September 12, 2016 DMICC meeting mstockstill on DSK3G9T082PROD with NOTICES SUMMARY: VerDate Sep<11>2014 20:04 Aug 29, 2016 Jkt 238001 will focus on the Diabetes and Neurocognition. Any member of the public interested in presenting oral comments to the Committee should notify the contact person listed on this notice at least 10 days in advance of the meeting. Interested individuals and representatives or organizations should submit a letter of intent, a brief description of the organization represented, and a written copy of their oral presentation in advance of the meeting. Only one representative of an organization will be allowed to present; oral comments and presentations will be limited to a maximum of 5 minutes. Printed and electronic copies are requested for the record. In addition, any interested person may file written comments with the Committee by forwarding their statement to the contact person listed on this notice. The statement should include the name, address, telephone number and when applicable, the business or professional affiliation of the interested person. Because of time constraints for the meeting, oral comments will be allowed on a first-come, first-serve basis. Members of the public who would like to receive email notification about future DMICC meetings should register for the listserv available on the DMICC Web site, www.diabetescommittee.gov. Dated: August 24, 2016. B. Tibor Roberts, Executive Secretary, DMICC, Office of Scientific Program and Policy Analysis, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health. [FR Doc. 2016–20824 Filed 8–29–16; 8:45 am] BILLING CODE 4140–01–P 59643 would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: National Institute on Aging Initial Review Group, Behavior and Social Science of Aging Review Committee. Date: September 29–30, 2016. Time: 4:00 p.m. to 2:00 p.m. Agenda: To review and evaluate grant applications. Place: Doubletree Hotel Bethesda, (Formerly Holiday Inn Select), 8120 Wisconsin Avenue, Bethesda, MD 20814. Contact Person: Kimberly Firth, Ph.D., National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2W200, Bethesda, MD 20892, 301–402–7702, kimberly.firth@nih.gov. Name of Committee: National Institute on Aging Initial Review Group, Clinical Aging Review Committee. Date: September 29–30, 2016. Time: 4:00 p.m. to 1:00 p.m. Agenda: To review and evaluate grant applications. Place: Doubletree Hotel Bethesda, (Formerly Holiday Inn Select), 8120 Wisconsin Avenue, Bethesda, MD 20814. Contact Person: Alicja L. Markowska, Ph.D., DSC, National Institute on Aging, National Institutes of Health, Gateway Building 2W200, 7201 Wisconsin Avenue, Bethesda, MD 20892, 301–496–9666, markowsa@nia.nih.gov. (Catalogue of Federal Domestic Assistance Program Nos. 93.866, Aging Research, National Institutes of Health, HHS) Dated: August 24, 2016. Melanie J. Gray, Program Analyst, Office of Federal Advisory Committee Policy. [FR Doc. 2016–20727 Filed 8–29–16; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institute of Mental Health; Notice of Closed Meeting National Institutes of Health Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is hereby given of the following meeting. The meeting will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. National Institute on Aging; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is hereby given of the following meetings. The meetings will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which PO 00000 Frm 00047 Fmt 4703 Sfmt 4703 Name of Committee: National Institute of Mental Health Special Emphasis Panel. E:\FR\FM\30AUN1.SGM 30AUN1

Agencies

[Federal Register Volume 81, Number 168 (Tuesday, August 30, 2016)]
[Notices]
[Pages 59642-59643]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2016-20834]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Office of the Secretary


Findings of Research Misconduct

AGENCY: Office of the Secretary, HHS.

ACTION: Notice.

-----------------------------------------------------------------------

SUMMARY: Notice is hereby given that the Office of Research Integrity 
(ORI) has taken final action in the following case:
    Andrew R. Cullinane, Ph.D., National Institutes of Health: Based on 
Respondent's admission, an assessment conducted by the National 
Institutes of Health (NIH), and analysis conducted by ORI in its 
oversight review, ORI found that Dr. Andrew R. Cullinane, former 
postdoctoral fellow, Medical Genetics Branch, National Human Genome 
Research Institute (NHGRI), NIH, engaged in research misconduct in 
research supported by NHGRI, NIH.
    ORI found that Respondent engaged in research misconduct by 
reporting falsified and/or fabricated data in the following two (2) 
publications and one (1) submitted manuscript:

 Am. J. Hum. Genet. 88(6):778-787, 2011 (hereafter referred to 
as ``Paper 1'')
 Neurology 86(14):1320-1328, 2016 (hereafter referred to as 
``Paper 2'')
 ``RAB11FIP1, Mutated in HPS-10, Interacts with BLOC-1 to 
Mitigate Recycling of Melanogenic Proteins.'' Submitted for publication 
to The Journal of Clinical Investigations, Cell, Nature Biology, 
Molecular Cell, and Nature Genetics (hereafter referred to as 
``Manuscript 1'')

    ORI found that Respondent knowingly falsified and/or fabricated 
data and related images by alteration and/or reuse and/or relabeling of 
experimental data. Specifically:

 in Paper 1, Respondent falsified and/or fabricated the results 
in Figure 3C by using the same gel images to represent expression of 
PLDN in fibroblasts and melanocytes
 in Paper 2, Respondent falsified and/or fabricated the results 
in Figure 2A by erasure of a band in the blot image for LYST/CHD-4 that 
was present in the original data
 in Manuscript 1, Respondent falsified and/or fabricated the 
results in Western blot data by reuse and relabeling, duplication, and/
or manipulation in Figures 2B, 2D, 2E, 3A-C, 4C, 4E, 4G, 5B, 6A-C, 7A, 
7D, 7G, 7J, and Supplemental Figure 3, and Respondent falsified and/or 
fabricated the results by reuse and relabeling of centrifuge tubes to 
represent different experiments in Figures 1D, 7C, 7F, 7I, 7L, and 
Supplemental Figure 2

    Dr. Cullinane has entered into a Voluntary Settlement Agreement 
with ORI and NIH, in which he voluntarily agreed:
    (1) To have his research supervised for a period of three (3) years 
beginning on July 22, 2016; Respondent agreed to ensure that prior to 
the submission of an application for U.S. Public Health Service (PHS) 
support for a research project on which Respondent's participation is 
proposed and prior to Respondent's participation in any capacity on 
PHS-supported research, the institution employing him must submit a 
plan for supervision of his duties to ORI for approval. The plan for 
supervision must be designed to ensure the scientific integrity of 
Respondent's research contribution; Respondent agreed that he will not 
participate in any PHS-supported research until a plan for supervision 
is submitted to and approved by ORI; Respondent agreed to maintain 
responsibility for compliance with the agreed upon supervision plan;
    (2) that for a period of three (3) years beginning on July 22, 
2016, any institution employing him shall submit, in conjunction with 
each application for PHS funds, or report, manuscript, or abstract 
involving PHS-supported research in which Respondent is involved, a 
certification to ORI that the data provided by Respondent are based on 
actual experiments or are otherwise legitimately derived and that the 
data, procedures, and methodology are accurately reported in the 
application, report, manuscript, or abstract;
    (3) to exclude himself from serving in any advisory capacity to PHS 
including, but not limited to, service on any PHS advisory committee, 
board, and/or peer review committee, or as a consultant for a period of 
three (3) years, beginning on July 22, 2016; and
    (4) as a condition of the Agreement, Respondent agreed to the 
retraction or correction of:

 Am. J. Hum. Genet. 88(6):778-787, 2011

[[Page 59643]]

 Neurology 86(14):1320-1328, 2016

FOR FURTHER INFORMATION CONTACT: Director, Office of Research 
Integrity, 1101 Wootton Parkway, Suite 750, Rockville, MD 20852, (240) 
453-8200.

Kathryn M. Partin,
Director, Office of Research Integrity.
[FR Doc. 2016-20834 Filed 8-29-16; 8:45 am]
 BILLING CODE 4150-31-P
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