Request for Data and Information on Technologies Used To Identify Substances With the Potential To Cause Acute Systemic Toxicity, 46696 [2016-16840]

Download as PDF 46696 Federal Register / Vol. 81, No. 137 / Monday, July 18, 2016 / Notices provisions set forth in sections 552b(c)(4) and 552b(c)(6), title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: National Eye Institute Special Emphasis Panel; NEI Translational Research (R24) and Patient-Oriented Mentored Training (K23) Grant Applications. Date: August 4, 2016. Time: 8:00 a.m. to 5:00 p.m. Agenda: To review and evaluate grant applications. Place: Embassy Suites at the Chevy Chase Pavilion, Tenleytown Ballroom II, 4300 Military Road NW., Washington, DC 20015. Contact Person: Anne E. Schaffner, Ph.D., Chief, Scientific Review Branch Division of Extramural Research, National Eye Institute, 5635 Fishers Lane, Suite 1300, MSC 9300, Bethesda, MD 20892–9300, (301) 451–2020, aes@nei.nih.gov. (Catalogue of Federal Domestic Assistance Program Nos. 93.867, Vision Research, National Institutes of Health, HHS) Dated: July 12, 2016. Natasha M. Copeland, Program Analyst, Office of Federal Advisory Committee Policy. [FR Doc. 2016–16833 Filed 7–15–16; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Request for Data and Information on Technologies Used To Identify Substances With the Potential To Cause Acute Systemic Toxicity The National Toxicology Program (NTP) Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) requests data and information on approaches and/or technologies currently used to identify substances with the potential to cause acute systemic toxicity when swallowed, inhaled, or absorbed through the skin. Submitted information will be used to assess the state of the science and determine technical needs for nonanimal test methods used to evaluate the potential of chemicals to induce acute systemic toxicity. DATES: Receipt of information: Deadline is September 1, 2016. ADDRESSES: Data and information should be submitted electronically to niceatm@niehs.nih.gov. asabaliauskas on DSK3SPTVN1PROD with NOTICES SUMMARY: VerDate Sep<11>2014 17:52 Jul 15, 2016 Jkt 238001 Dr. Warren Casey, Director, NICEATM; email: warren.casey@nih.gov; telephone: (919) 316–4729. SUPPLEMENTARY INFORMATION: Background: Acute systemic toxicity tests are conducted to determine the potential for a single or short-term dose of a substance to cause illness or death when inhaled (inhalation toxicity testing), swallowed (oral toxicity testing), or absorbed through the skin (dermal toxicity testing). These tests are required by multiple regulatory agencies and can use large numbers of animals. NICEATM, which fosters the evaluation and promotion of alternative test methods for regulatory use, supports efforts to develop, validate, and implement alternative approaches for acute systemic toxicity testing that replace, reduce, or refine use of animals in testing. Request for Information: NICEATM requests data and information on approaches and/or technologies currently used to identify substances with the potential to cause acute systemic toxicity. Respondents should provide information on any activities relevant to the development or validation of alternatives to in vivo tests currently required by regulatory agencies that assess acute oral, dermal, or inhalation toxicity. Of specific interest are chemical-specific data from non-animal tests for acute systemic toxicity hazard, as well as available data on the same chemicals from in vivo acute systemic toxicity tests, such as ethical human or animal studies or accidental human exposures. Respondents to this request for information should include their name, affiliation (if applicable), mailing address, telephone, email, and sponsoring organization (if any) with their communications. The deadline for receipt of the requested information is September 1, 2016. Responses to this notice will be posted at https:// ntp.niehs.nih.gov/go/iv-data. Persons submitting responses will be identified on the Web page by name and affiliation or sponsoring organization, if applicable. Responses to this request are voluntary. No proprietary, classified, confidential, or sensitive information should be included in responses. This request for information is for planning purposes only and is not a solicitation for applications or an obligation on the part of the U.S. Government to provide support for any ideas identified in response to the request. Please note that the U.S. Government will not pay for the preparation of any information FOR FURTHER INFORMATION CONTACT: PO 00000 Frm 00057 Fmt 4703 Sfmt 4703 submitted or for its use of that information. Background Information on NICEATM: NICEATM conducts data analyses, workshops, independent validation studies, and other activities to assess new, revised, and alternative test methods and strategies. NICEATM also provides support for the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM). The ICCVAM Authorization Act of 2000 (42 U.S.C. 285l–3) provides authority for ICCVAM and NICEATM in the development of alternative test methods. Information about NICEATM and ICCVAM is found at https:// ntp.niehs.nih.gov/go/niceatm and https://ntp.niehs.nih.gov/go/iccvam. Dated: July 12, 2016. John R. Bucher, Associate Director, National Toxicology Program. [FR Doc. 2016–16840 Filed 7–15–16; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Notice of Kidney Interagency Coordinating Committee Meeting The Kidney Interagency Coordinating Committee (KICC) will hold a meeting on September 19, 2016, on ‘‘CRIC and CKiD: Using longitudinal CKD cohort study findings to plan population health interventions.’’ The meeting is open to the public. DATES: The meeting will be held on September 19, 2016, 9 a.m. to 12 p.m. Individuals wanting to present oral comments must notify the contact person at least 10 days before the meeting date. ADDRESSES: The meeting will be held in the Natcher Conference Center on the NIH Campus at 9000 Rockville Pike, Bethesda, MD 20894. FOR FURTHER INFORMATION CONTACT: For further information concerning this meeting, contact Dr. Andrew S. Narva, Executive Secretary of the Kidney Interagency Coordinating Committee, National Institute of Diabetes and Digestive and Kidney Diseases, 6707 Democracy Blvd., MSC 5458, Bethesda, MD 20892–5458, telephone: 301–594– 8864; FAX: 301–480–3510; email: healthinfo@niddk.nih.gov. SUPPLEMENTARY INFORMATION: The KICC, chaired by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), comprises members of the Department of Health and Human SUMMARY: E:\FR\FM\18JYN1.SGM 18JYN1

Agencies

[Federal Register Volume 81, Number 137 (Monday, July 18, 2016)]
[Notices]
[Page 46696]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2016-16840]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Request for Data and Information on Technologies Used To Identify 
Substances With the Potential To Cause Acute Systemic Toxicity

SUMMARY: The National Toxicology Program (NTP) Interagency Center for 
the Evaluation of Alternative Toxicological Methods (NICEATM) requests 
data and information on approaches and/or technologies currently used 
to identify substances with the potential to cause acute systemic 
toxicity when swallowed, inhaled, or absorbed through the skin. 
Submitted information will be used to assess the state of the science 
and determine technical needs for non-animal test methods used to 
evaluate the potential of chemicals to induce acute systemic toxicity.

DATES: Receipt of information: Deadline is September 1, 2016.

ADDRESSES: Data and information should be submitted electronically to 
niceatm@niehs.nih.gov.

FOR FURTHER INFORMATION CONTACT: Dr. Warren Casey, Director, NICEATM; 
email: warren.casey@nih.gov; telephone: (919) 316-4729.

SUPPLEMENTARY INFORMATION: 
    Background: Acute systemic toxicity tests are conducted to 
determine the potential for a single or short-term dose of a substance 
to cause illness or death when inhaled (inhalation toxicity testing), 
swallowed (oral toxicity testing), or absorbed through the skin (dermal 
toxicity testing). These tests are required by multiple regulatory 
agencies and can use large numbers of animals. NICEATM, which fosters 
the evaluation and promotion of alternative test methods for regulatory 
use, supports efforts to develop, validate, and implement alternative 
approaches for acute systemic toxicity testing that replace, reduce, or 
refine use of animals in testing.
    Request for Information: NICEATM requests data and information on 
approaches and/or technologies currently used to identify substances 
with the potential to cause acute systemic toxicity. Respondents should 
provide information on any activities relevant to the development or 
validation of alternatives to in vivo tests currently required by 
regulatory agencies that assess acute oral, dermal, or inhalation 
toxicity. Of specific interest are chemical-specific data from non-
animal tests for acute systemic toxicity hazard, as well as available 
data on the same chemicals from in vivo acute systemic toxicity tests, 
such as ethical human or animal studies or accidental human exposures.
    Respondents to this request for information should include their 
name, affiliation (if applicable), mailing address, telephone, email, 
and sponsoring organization (if any) with their communications. The 
deadline for receipt of the requested information is September 1, 2016. 
Responses to this notice will be posted at https://ntp.niehs.nih.gov/go/iv-data. Persons submitting responses will be identified on the Web 
page by name and affiliation or sponsoring organization, if applicable.
    Responses to this request are voluntary. No proprietary, 
classified, confidential, or sensitive information should be included 
in responses. This request for information is for planning purposes 
only and is not a solicitation for applications or an obligation on the 
part of the U.S. Government to provide support for any ideas identified 
in response to the request. Please note that the U.S. Government will 
not pay for the preparation of any information submitted or for its use 
of that information.
    Background Information on NICEATM: NICEATM conducts data analyses, 
workshops, independent validation studies, and other activities to 
assess new, revised, and alternative test methods and strategies. 
NICEATM also provides support for the Interagency Coordinating 
Committee on the Validation of Alternative Methods (ICCVAM). The ICCVAM 
Authorization Act of 2000 (42 U.S.C. 285l-3) provides authority for 
ICCVAM and NICEATM in the development of alternative test methods. 
Information about NICEATM and ICCVAM is found at https://ntp.niehs.nih.gov/go/niceatm and https://ntp.niehs.nih.gov/go/iccvam.

    Dated: July 12, 2016.
John R. Bucher,
Associate Director, National Toxicology Program.
[FR Doc. 2016-16840 Filed 7-15-16; 8:45 am]
 BILLING CODE 4140-01-P
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