National Institute on Drug Abuse; Notice of Closed Meeting, 44034-44035 [2016-15884]
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Federal Register / Vol. 81, No. 129 / Wednesday, July 6, 2016 / Notices
compared to traditional fixatives.
Additionally, BE70 is compatible with
current protocols and does not alter
tissue processing. In vitro an in vivo
data are available and the fixative has
been tested on paraffin-embedded
samples.
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
Government-Owned Inventions;
Availability for Licensing
AGENCY:
National Institutes of Health,
HHS.
ACTION:
Notice.
The invention listed below is
owned by an agency of the U.S.
Government and is available for
licensing in the U.S. in accordance with
35 U.S.C. 209 and 37 CFR part 404 to
achieve expeditious commercialization
of results of federally-funded research
and development. Foreign patent
applications are filed on selected
inventions to extend market coverage
for companies and may also be available
for licensing.
ADDRESSES: Invention Development and
Marketing Unit, Technology Transfer
Center, National Cancer Institute, 9609
Medical Center Drive, Mail Stop 9702,
Rockville, MD 20850–9702.
FOR FURTHER INFORMATION CONTACT:
Information on licensing, and copies of
the U.S. patent applications listed below
may be obtained by contacting: Attn.
Invention Development and Marketing
Unit, Technology Transfer Center,
National Cancer Institute, 9609 Medical
Center Drive, Mail Stop 9702, Rockville,
MD 20850–9702, Tel. 240–276–5515 or
email ncitechtransfer@mail.nih.gov. A
signed Confidential Disclosure
Agreement may be required to receive
copies of the patent applications.
SUPPLEMENTARY INFORMATION:
Technology description follows.
Title of Invention: Improved Fixative
for Paraffin-Embedded Tissue Samples.
ehiers on DSK5VPTVN1PROD with NOTICES
SUMMARY:
Description of Technology
Tissues samples collected during
medical procedures, such as biopsies,
are used to diagnose a wide variety of
diseases. Before diagnosis, patient
samples are typically processed by
fixation and paraffin embedding. This
fixation/embedding process is used to
preserve tissue morphology and
histology for subsequent evaluation.
Unfortunately, most fixative agents
damage or destroy nucleic acids (RNA
and DNA) and proteins, thereby
potentially impairing diagnostic
assessment of tissue.
Researchers in the National Cancer
Institute’s Laboratory of Pathology have
developed an improved tissue fixative
solution that is formaldehyde-free. This
fixative, BE70, significantly improves
DNA, RNA, and protein biomolecule
integrity in histological samples
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Potential Commercial Applications
• Improves integrity of fixed tissue
samples.
• Improves RNA/DNA quality in
fixed tissue samples.
• Non-cross linking, improves protein
quality.
Value Proposition
• There is substantial interest in new
fixatives to replace neutral buffered
formalin (a carcinogen) as primary
fixative agent for surgical pathology.
• BE70 overcomes several limitations
of other fixatives, including cost and
disposal issues.
• Could be formulated as a
concentrate, and marketed as an
additive (to be added during dilution of
ethanol).
Development Stage
In vivo data: YES.
Inventor(s)
Stephen M. Hewitt (NCI), Joon-Yong
Chung (NCI), Candice D. Perry (Leidos
Biomedical LLC).
Intellectual Property
HHS Reference No. E–139–2015/0–
US–01 US Provisional Patent
Application 62/255,030 (HHS Reference
No. E–139–2015/0–US–01) filed
November 13, 2015, entitled ‘‘Fixative
and Methods of Use’’.
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
National Institute on Aging; Notice of
Closed Meeting
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. App.), notice is
hereby given of the following meeting.
The meeting will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: National Institute on
Aging Special Emphasis Panel; Delirium
Research Networks.
Date: July 29, 2016.
Time: 2:00 p.m. to 5:00 p.m.
Agenda: To review and evaluate grant
applications.
Place: National Institute on Aging,
Gateway Building, Suite 2W200, 7201
Wisconsin Avenue, Bethesda, MD 20892,
(Telephone Conference Call).
Contact Person: Isis S. Mikhail, DRPH, MD,
MPH, National Institute on Aging, Gateway
Building, 7201 Wisconsin Avenue, Suite
2W200, Bethesda, MD 20892, 301–402–7704.
mikhaili@mail.nih.gov.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.866, Aging Research,
National Institutes of Health, HHS)
Dated: June 29, 2016.
Melanie J. Gray,
Program Analyst, Office of Federal Advisory
Committee Policy.
[FR Doc. 2016–15882 Filed 7–5–16; 8:45 am]
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Publications
Perry C, Chung JY, et al. J Histochem
Cytochem. 2016 May 24; E-pub [PMID:
27221702].
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Contact Information
National Institutes of Health
Requests for copies of the patent
application or inquiries about licensing,
research collaborations, and codevelopment opportunities should be
sent to John D. Hewes, Ph.D., email:
john.hewes@nih.gov.
National Institute on Drug Abuse;
Notice of Closed Meeting
Dated: June 28, 2016.
John D. Hewes,
Technology Transfer Specialist, Technology
Transfer Center, National Cancer Institute.
[FR Doc. 2016–15890 Filed 7–5–16; 8:45 am]
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Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. App), notice is
hereby given of the following meeting.
The meeting will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
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Federal Register / Vol. 81, No. 129 / Wednesday, July 6, 2016 / Notices
property such as patentable material,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: National Institute on
Drug Abuse Special Emphasis Panel; R13
Conference Grant Review.
Date: July 21, 2016.
Time: 11:00 a.m. to 3:00 p.m.
Agenda: To review and evaluate grant
applications.
Place: National Institutes of Health,
Neuroscience Center, 6001 Executive
Boulevard, Rockville, MD 20852 (Virtual
Meeting).
Contact Person: Susan O. McGuire, Ph.D.,
Scientific Review Officer, Office of
Extramural Affairs, National Institute on
Drug Abuse, National Institutes of Health,
DHHS, 6001 Executive Blvd., Room 4245,
Rockville, MD 20852, 301–435–1426,
mcguireso@mail.nih.gov.
(Catalogue of Federal Domestic Assistance
Program Nos.: 93.279, Drug Abuse and
Addiction Research Programs, National
Institutes of Health, HHS)
Dated: June 29, 2016.
Natasha M. Copeland,
Program Analyst, Office of Federal Advisory
Committee Policy.
[FR Doc. 2016–15884 Filed 7–5–16; 8:45 am]
BILLING CODE 4140–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
National Institute of Neurological
Disorders and Stroke; Notice of Closed
Meeting
ehiers on DSK5VPTVN1PROD with NOTICES
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. App.), notice is
hereby given of the following meeting.
The meeting will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: National Institute of
Neurological Disorders and Stroke, Special
Emphasis Panel; Recording and Modulation
in the Human CNS.
Date: July 1, 2016.
Time: 8:00 a.m. to 5:00 p.m.
Agenda: To review and evaluate grant
applications.
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Place: Admiral Fell Inn, 888 South
Broadway, Baltimore, MD 21231.
Contact Person: Ernest Lyons, Ph.D.,
Scientific Review Administrator, Scientific
Review Branch, NINDS/NIH/DHHS,
Neuroscience Center, 6001 Executive Blvd.,
Suite 3204, MSC 9529, Bethesda, MD 20892–
9529, 301–496–4056, lyonse@ninds.nih.gov.
This notice is being published less than 15
days prior to the meeting due to the timing
limitations imposed by the review and
funding cycle.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.853, Clinical Research
Related to Neurological Disorders; 93.854,
Biological Basis Research in the
Neurosciences, National Institutes of Health,
HHS)
Dated: June 29, 2016.
Sylvia L. Neal,
Program Analyst, Office of Federal Advisory
Committee Policy.
[FR Doc. 2016–15885 Filed 7–5–16; 8:45 am]
BILLING CODE 4140–01–P
National Institutes of Health
National Institute on Aging; Notice of
Closed Meeting
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. App.), notice is
hereby given of the following meeting.
The meeting will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: National Institute on
Aging Special Emphasis Panel; Epigenomics
of Aging.
Date: July 26, 2016.
Time: 10:00 a.m. to 1:00 p.m.
Agenda: To review and evaluate grant
applications.
Place: National Institute on Aging,
Gateway Building, Suite 2W200, 7201
Wisconsin Avenue, Bethesda, MD 20892
(Telephone Conference Call).
Contact Person: Kimberly Firth, Ph.D.,
National Institutes of Health National
Institute on Aging Gateway Building, 7201
Wisconsin Avenue, Suite 2C212, Bethesda,
MD 20892, 301–402–7702, firthkm@
mail.nih.gov.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.866, Aging Research,
National Institutes of Health, HHS)
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Dated: June 29, 2016.
Melanie J. Gray,
Program Analyst, Office of Federal Advisory
Committee Policy.
[FR Doc. 2016–15879 Filed 7–5–16; 8:45 am]
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DEPARTMENT OF HOMELAND
SECURITY
Coast Guard
[Docket No. USCG–2016–0106]
Collection of Information Under
Review by Office of Management and
Budget; OMB Control Number: 1625–
0104
Coast Guard, DHS.
Thirty-day notice requesting
comments.
AGENCY:
ACTION:
In compliance with the
Paperwork Reduction Act of 1995 the
U.S. Coast Guard is forwarding an
Information Collection Request (ICR),
abstracted below, to the Office of
Management and Budget (OMB), Office
of Information and Regulatory Affairs
(OIRA), requesting approval of a
revision to the following collection of
information: 1625–0104, Barges
Carrying Bulk Hazardous Materials. Our
ICR describes the information we seek
to collect from the public. Review and
comments by OIRA ensure we only
impose paperwork burdens
commensurate with our performance of
duties.
DATES: Comments must reach the Coast
Guard and OIRA on or before August 5,
2016.
ADDRESSES: You may submit comments
identified by Coast Guard docket
number [USCG–2016–0106] to the Coast
Guard using the Federal eRulemaking
Portal at https://www.regulations.gov.
Alternatively, you may submit
comments to OIRA using one of the
following means:
(1) Email: OIRAsubmission@omb.eop.gov.
(2) Mail: OIRA, 725 17th Street NW.,
Washington, DC 20503, attention Desk
Officer for the Coast Guard.
(3) Fax: 202–395–6566. To ensure
your comments are received in a timely
manner, mark the fax, attention Desk
Officer for the Coast Guard.
A copy of the ICR is available through
the docket on the Internet at https://
www.regulations.gov. Additionally,
copies are available from: Commandant
(CG–612), Attn: Paperwork Reduction
Act Manager, U.S. Coast Guard, 2703
Martin Luther King Jr Ave. SE., Stop
7710, Washington, DC 20593–7710.
SUMMARY:
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
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Agencies
[Federal Register Volume 81, Number 129 (Wednesday, July 6, 2016)]
[Notices]
[Pages 44034-44035]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2016-15884]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health
National Institute on Drug Abuse; Notice of Closed Meeting
Pursuant to section 10(d) of the Federal Advisory Committee Act, as
amended (5 U.S.C. App), notice is hereby given of the following
meeting.
The meeting will be closed to the public in accordance with the
provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5
U.S.C., as amended. The grant applications and the discussions could
disclose confidential trade secrets or commercial
[[Page 44035]]
property such as patentable material, and personal information
concerning individuals associated with the grant applications, the
disclosure of which would constitute a clearly unwarranted invasion of
personal privacy.
Name of Committee: National Institute on Drug Abuse Special
Emphasis Panel; R13 Conference Grant Review.
Date: July 21, 2016.
Time: 11:00 a.m. to 3:00 p.m.
Agenda: To review and evaluate grant applications.
Place: National Institutes of Health, Neuroscience Center, 6001
Executive Boulevard, Rockville, MD 20852 (Virtual Meeting).
Contact Person: Susan O. McGuire, Ph.D., Scientific Review
Officer, Office of Extramural Affairs, National Institute on Drug
Abuse, National Institutes of Health, DHHS, 6001 Executive Blvd.,
Room 4245, Rockville, MD 20852, 301-435-1426,
mcguireso@mail.nih.gov.
(Catalogue of Federal Domestic Assistance Program Nos.: 93.279, Drug
Abuse and Addiction Research Programs, National Institutes of
Health, HHS)
Dated: June 29, 2016.
Natasha M. Copeland,
Program Analyst, Office of Federal Advisory Committee Policy.
[FR Doc. 2016-15884 Filed 7-5-16; 8:45 am]
BILLING CODE 4140-01-P