Government-Owned Inventions; Availability for Licensing, 41585-41586 [2016-15059]

Download as PDF Federal Register / Vol. 81, No. 123 / Monday, June 27, 2016 / Notices Dated: June 21, 2016. Michelle Trout, Program Analyst, Office of Federal Advisory Committee Policy. [FR Doc. 2016–15064 Filed 6–24–16; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings mstockstill on DSK3G9T082PROD with NOTICES Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is hereby given of the following meetings. The meetings will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: Center for Scientific Review Special Emphasis Panel; Implementation and Dissemination Science for HIV/AIDS. Date: July 8, 2016. Time: 10:00 a.m. to 6:30 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892 (Virtual Meeting). Contact Person: Shalanda A Bynum, Ph.D., MPH, Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 3206, Bethesda, MD 20892; 301–755–4355; bynumsa@csr.nih.gov. This notice is being published less than 15 days prior to the meeting due to the timing limitations imposed by the review and funding cycle. Name of Committee: Center for Scientific Review Special Emphasis Panel; Member Conflict: Cardiovascular Sciences. Date: July 13–14, 2016. Time: 9:00 a.m. to 5:00 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892 (Virtual Meeting). Contact Person: Kimm Hamann, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 4118A, MSC 7814, Bethesda, MD 20892; 301–435– 5575; hamannkj@csr.nih.gov. This notice is being published less than 15 days prior to the meeting due to the timing VerDate Sep<11>2014 18:52 Jun 24, 2016 Jkt 238001 limitations imposed by the review and funding cycle. Name of Committee: AIDS and Related Research Integrated Review Group; Behavioral and Social Consequences of HIV/ AIDS Study Section. Date: July 18–19, 2016. Time: 8:00 a.m. to 5:00 p.m. Agenda: To review and evaluate grant applications. Place: Westin Grand, 2350 M Street NW., Washington, DC 20037. Contact Person: Mark P. Rubert, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 5218, MSC 7852, Bethesda, MD 20892; 301–806– 6596; rubertm@csr.nih.gov. Name of Committee: Center for Scientific Review Special Emphasis Panel; Member Conflict: Topics in Bacterial Pathogenesis and Host Interactions. Date: July 18, 2016. Time: 10:00 a.m. to 6:00 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892. Contact Person:Soheyla Saadi, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 3211, MSC 7808, Bethesda, MD 20892; 301–435– 0903; saadisoh@csr.nih.gov. Name of Committee: Center for Scientific Review Special Emphasis Panel; Member Conflict: Gastrointestinal and Liver Pathophysiology and Toxicology. Date: July 20–21, 2016. Time: 9:00 a.m. to 6:00 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892 (Virtual Meeting). Contact Person: Atul Sahai, Ph.D., Scientific Review Officer, Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Room 2188, MSC 7818, Bethesda, MD 20892; 301–435– 1198; sahaia@csr.nih.gov. (Catalogue of Federal Domestic Assistance Program Nos. 93.306, Comparative Medicine; 93.333, Clinical Research, 93.306, 93.333, 93.337, 93.393–93.396, 93.837–93.844, 93.846–93.878, 93.892, 93.893, National Institutes of Health, HHS) Dated: June 21, 2016. Sylvia L. Neal, Program Analyst, Office of Federal Advisory Committee Policy. [FR Doc. 2016–15054 Filed 6–24–16; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Government-Owned Inventions; Availability for Licensing AGENCY: PO 00000 National Institutes of Health. Frm 00078 Fmt 4703 Sfmt 4703 ACTION: 41585 Notice. The invention listed below is owned by an agency of the U.S. Government and is available for licensing and/or co-development in the U.S. in accordance with 35 U.S.C. 209 and 37 CFR part 404 to achieve expeditious commercialization of results of federally-funded research and development. Foreign patent applications are filed on selected inventions to extend market coverage for companies and may also be available for licensing and/or co-development. ADDRESSES: Invention Development and Marketing Unit, Technology Transfer Center, National Cancer Institute, 9609 Medical Center Drive, Mail Stop 9702, Rockville, MD 20850–9702. FOR FURTHER INFORMATION CONTACT: Information on licensing and codevelopment research collaborations, and copies of the U.S. patent applications listed below may be obtained by contacting: Attn. Invention Development and Marketing Unit, Technology Transfer Center, National Cancer Institute, 9609 Medical Center Drive, Mail Stop 9702, Rockville, MD 20850–9702, Tel. 240–276–5515 or email ncitechtransfer@mail.nih.gov. A signed Confidential Disclosure Agreement may be required to receive copies of the patent applications. SUPPLEMENTARY INFORMATION: Technology description follows. Title of invention: Biomarker signature development: microRNAs as biodosimetry markers. Description of Technology: Alterations in microRNAs (miRNAs), a type of small non-coding RNAs, have been reported in cells/tumors subjected to radiation exposure, implying that miRNAs play an important role in cellular stress response to radiation. Researchers at the National Cancer Institute evaluated small non-coding RNAs, long non-coding RNAs (lncRNA), and mRNA as potential non-invasive biomarkers for radiation biodosimetry. While the use of miRNAs as radiation biomarkers has been reported, the integrated use of miRNAs, mRNAs and lncRNAs to accurately determine radiation doses is novel and has not been published. The researchers characterized a unique method of examining miRNA levels along with levels of its target mRNA and lncRNA to determine radiation exposure using whole blood samples from mice exposed to 2, 4, 8, 12 and 15 Gy irradiation. In doing so, they discovered distinct miRNA, mRNA and lncRNA biomarker signatures that inform degree of radiation exposure. SUMMARY: E:\FR\FM\27JNN1.SGM 27JNN1 41586 Federal Register / Vol. 81, No. 123 / Monday, June 27, 2016 / Notices mstockstill on DSK3G9T082PROD with NOTICES Integrated analysis of miRNA, mRNAs, and lncRNAs to assess radiation exposure after mass-casualty incidents could provide a valuable tool in identifying biomarkers, and in the development and appropriate implementation of effective medical countermeasures. This application could potentially also be used to immediately detect, and therefore circumvent or mitigate non-specific injury from cancer radiotherapy treatments. Potential Commercial Applications: • Diagnostic for radiation exposure, including for therapeutic procedures. Value Proposition: • Blood-based biomarker assay for circulating miRNAs. • Could be developed as part of point-of-care and high-throughput screening platforms. • Immediate medical care based on amount of radiation exposure is critical for giving appropriate care to affected individuals. Development Stage: In-vivo testing. Inventor(s): Molykutty Aryankalayil (NCI), Norman Coleman (NCI), Adeola Makinde (NCI). Intellectual Property: HHS Reference No. E–066–2015/0– US–01 US Provisional Application 62/ 244,044 (HHS Reference No. E–066– 2016/0–US–01) filed October 20, 2015 entitled ‘‘Biomarker signature development: microRNAs as biodosimetry markers’’ Collaboration Opportunity: Researchers at the NCI seek parties interested in licensing or codevelopment for microRNA biomarker signatures as biodosimetry markers. Contact Information: Requests for copies of the patent application or inquiries about licensing, research collaborations, and codevelopment opportunities should be sent to John D. Hewes, Ph.D., email: john.hewes@nih.gov or phone: 240–276– 5515. Dated: June 20, 2016. John D. Hewes, Technology Transfer Specialist, Technology Transfer Center, National Cancer Institute. [FR Doc. 2016–15059 Filed 6–24–16; 8:45 am] BILLING CODE 4140–01–P VerDate Sep<11>2014 20:12 Jun 24, 2016 Jkt 238001 DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Neurological Disorders and Stroke; Notice of Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is hereby given of a meeting of the National Advisory Neurological Disorders and Stroke Council. The meeting will be open to the public as indicated below, with attendance limited to space available. Individuals who plan to attend and need special assistance, such as sign language interpretation or other reasonable accommodations, should notify the Contact Person listed below in advance of the meeting. The meeting will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable materials, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: National Advisory Neurological Disorders and Stroke Council. Date: September 15–16, 2016. Open: September 15, 2016, 8:00 a.m. to 2:30 p.m. Agenda: Report by the Director, NINDS; Report by the Associate Director for Extramural Research; Administrative and Program Developments; and an Overview of the NINDS Intramural Program. Place: National Institutes of Health, Building 31, 31 Center Drive, 6th Floor, Conference Room 10, Bethesda, MD 20892. Closed: September 15, 2016, 2:30 p.m. to 4:45 p.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, Building 31, 31 Center Drive, 6th Floor, Conference Room 10, Bethesda, MD 20892. Closed: September 15, 2016, 4:45 p.m. to 5:15 p.m. Agenda: To review and evaluate the Division of Intramural Research Board of Scientific Counselors’ Reports. Place: National Institutes of Health, Building 31, 31 Center Drive, 6th Floor, Conference Room 10, Bethesda, MD 20892. Closed: September 16, 2016, 8:00 a.m. to 11:00 a.m. Agenda: To review and evaluate grant applications. Place: National Institutes of Health, Building 31, 31 Center Drive, 6th Floor, Conference Room 10, Bethesda, MD 20892. PO 00000 Frm 00079 Fmt 4703 Sfmt 4703 Contact Person: Robert Finkelstein, Ph.D., Director of Extramural Research, National Institute of Neurological Disorders and Stroke, NIH, 6001 Executive Blvd., Suite 3309, MSC 9531, Bethesda, MD 20892, (301) 496–9248. Any interested person may file written comments with the committee by forwarding the statement to the Contact Person listed on this notice. The statement should include the name, address, telephone number and when applicable, the business or professional affiliation of the interested person. In the interest of security, NIH has instituted stringent procedures for entrance onto the NIH campus. All visitor vehicles, including taxicabs, hotel, and airport shuttles will be inspected before being allowed on campus. Visitors will be asked to show one form of identification (for example, a government-issued photo ID, driver’s license, or passport) and to state the purpose of their visit. Information is also available on the Institute’s/Center’s home page: https:// www.ninds.nih.gov, where an agenda and any additional information for the meeting will be posted when available. (Catalogue of Federal Domestic Assistance Program Nos. 93.853, Clinical Research Related to Neurological Disorders; 93.854, Biological Basis Research in the Neurosciences, National Institutes of Health, HHS). Dated: June 21, 2016. Sylvia L. Neal, Program Analyst, Office of Federal Advisory Committee Policy. [FR Doc. 2016–15068 Filed 6–24–16; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is hereby given of the following meetings. The meetings will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: AIDS and Related Research Integrated Review Group; AIDS Molecular and Cellular Biology Study Section. Date: July 18, 2016. E:\FR\FM\27JNN1.SGM 27JNN1

Agencies

[Federal Register Volume 81, Number 123 (Monday, June 27, 2016)]
[Notices]
[Pages 41585-41586]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2016-15059]


-----------------------------------------------------------------------

DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Government-Owned Inventions; Availability for Licensing

AGENCY: National Institutes of Health.

ACTION: Notice.

-----------------------------------------------------------------------

SUMMARY: The invention listed below is owned by an agency of the U.S. 
Government and is available for licensing and/or co-development in the 
U.S. in accordance with 35 U.S.C. 209 and 37 CFR part 404 to achieve 
expeditious commercialization of results of federally-funded research 
and development. Foreign patent applications are filed on selected 
inventions to extend market coverage for companies and may also be 
available for licensing and/or co-development.

ADDRESSES: Invention Development and Marketing Unit, Technology 
Transfer Center, National Cancer Institute, 9609 Medical Center Drive, 
Mail Stop 9702, Rockville, MD 20850-9702.

FOR FURTHER INFORMATION CONTACT: Information on licensing and co-
development research collaborations, and copies of the U.S. patent 
applications listed below may be obtained by contacting: Attn. 
Invention Development and Marketing Unit, Technology Transfer Center, 
National Cancer Institute, 9609 Medical Center Drive, Mail Stop 9702, 
Rockville, MD 20850-9702, Tel. 240-276-5515 or email 
ncitechtransfer@mail.nih.gov. A signed Confidential Disclosure 
Agreement may be required to receive copies of the patent applications.

SUPPLEMENTARY INFORMATION: Technology description follows.
    Title of invention: Biomarker signature development: microRNAs as 
biodosimetry markers.
    Description of Technology:
    Alterations in microRNAs (miRNAs), a type of small non-coding RNAs, 
have been reported in cells/tumors subjected to radiation exposure, 
implying that miRNAs play an important role in cellular stress response 
to radiation.
    Researchers at the National Cancer Institute evaluated small non-
coding RNAs, long non-coding RNAs (lncRNA), and mRNA as potential non-
invasive biomarkers for radiation biodosimetry. While the use of miRNAs 
as radiation biomarkers has been reported, the integrated use of 
miRNAs, mRNAs and lncRNAs to accurately determine radiation doses is 
novel and has not been published. The researchers characterized a 
unique method of examining miRNA levels along with levels of its target 
mRNA and lncRNA to determine radiation exposure using whole blood 
samples from mice exposed to 2, 4, 8, 12 and 15 Gy irradiation. In 
doing so, they discovered distinct miRNA, mRNA and lncRNA biomarker 
signatures that inform degree of radiation exposure.

[[Page 41586]]

    Integrated analysis of miRNA, mRNAs, and lncRNAs to assess 
radiation exposure after mass-casualty incidents could provide a 
valuable tool in identifying biomarkers, and in the development and 
appropriate implementation of effective medical countermeasures. This 
application could potentially also be used to immediately detect, and 
therefore circumvent or mitigate non-specific injury from cancer 
radiotherapy treatments.
    Potential Commercial Applications:
     Diagnostic for radiation exposure, including for 
therapeutic procedures.
    Value Proposition:
     Blood-based biomarker assay for circulating miRNAs.
     Could be developed as part of point-of-care and high-
throughput screening platforms.
     Immediate medical care based on amount of radiation 
exposure is critical for giving appropriate care to affected 
individuals.
    Development Stage:
    In-vivo testing.
    Inventor(s):
    Molykutty Aryankalayil (NCI), Norman Coleman (NCI), Adeola Makinde 
(NCI).
    Intellectual Property:
    HHS Reference No. E-066-2015/0-US-01 US Provisional Application 62/
244,044 (HHS Reference No. E-066-2016/0-US-01) filed October 20, 2015 
entitled ``Biomarker signature development: microRNAs as biodosimetry 
markers''
    Collaboration Opportunity: Researchers at the NCI seek parties 
interested in licensing or co-development for microRNA biomarker 
signatures as biodosimetry markers.
    Contact Information:
    Requests for copies of the patent application or inquiries about 
licensing, research collaborations, and co-development opportunities 
should be sent to John D. Hewes, Ph.D., email: john.hewes@nih.gov or 
phone: 240-276-5515.

    Dated: June 20, 2016.
John D. Hewes,
Technology Transfer Specialist, Technology Transfer Center, National 
Cancer Institute.
[FR Doc. 2016-15059 Filed 6-24-16; 8:45 am]
BILLING CODE 4140-01-P
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