Centennial Challenges Vascular Tissue Challenge, 38225 [2016-13795]
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Federal Register / Vol. 81, No. 113 / Monday, June 13, 2016 / Notices
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vascularized organ tissue in an in vitro
environment while maintaining
metabolic functionality similar to their
in vivo functionality throughout a 30day survival period. NASA is providing
the prize purse. The Methuselah
Foundation’s New Organ Alliance is the
Allied Organization managing the
competition.
This is a ‘‘first to demonstrate’’
competition. Teams may submit their
intent to compete beginning June 13,
2016 and the competition will remain
open until the requirements of the rules
are met and a winner is announced or
until the Challenge Deadline of
September 30th, 2019.
DATES:
The Vascular Tissue
Challenge will be conducted and judged
at the laboratory facilities of the
participants.
ADDRESSES:
To
register for or get additional information
regarding the Vascular Tissue
Challenge, please visit: https://
www.neworgan.org/vtc-prize.php.
For general information on the NASA
Centennial Challenges Program please
visit: https://www.nasa.gov/challenges.
General questions and comments
regarding the program should be
addressed to Monsi Roman, Centennial
Challenges Program, NASA Marshall
Space Flight Center Huntsville, AL
35812. Email address: hq-stmdcentennialchallenges@mail.nasa.gov.
FOR FURTHER INFORMATION CONTACT:
Summary
BILLING CODE 4510–24–P
NATIONAL AERONAUTICS AND
SPACE ADMINISTRATION
Centennial Challenges Vascular Tissue
Challenge
National Aeronautics and
Space Administration (NASA).
AGENCY:
(16–041)
Notice.
This notice is issued in
accordance with 51 U.S.C. 20144(c). The
Vascular Tissue Challenge is open and
teams that wish to compete may now
register. Centennial Challenges is a
program of prize competitions to
stimulate innovation in technologies of
interest and value to NASA and the
nation. The Vascular Tissue Challenge
is a prize competition with a $500,000
prize purse for teams that can
successfully create thick, human
srobinson on DSK5SPTVN1PROD with NOTICES
SUMMARY:
VerDate Sep<11>2014
20:48 Jun 10, 2016
Jkt 238001
I. Prize Amounts
The total Vascular Tissue Challenge
prize purse is $500,000 (five hundred
thousand U.S. dollars). First place will
receive $300,000 (three hundred
thousand U.S. dollars). Two runners-up
may be awarded $100,000 (one hundred
thousand U.S. dollars) each. Entries
must meet specific requirements
detailed in the Rules to be eligible for
prize awards.
II. Eligibility
To be eligible to win a prize,
competitors must;
(1) Register and comply with all
requirements in the rules and Team
Agreement;
(2) In the case of a private entity, shall
be incorporated in and maintain a
primary place of business in the United
States, and in the case of an individual,
whether participating singly or in a
group, shall be a citizen or permanent
resident of the United States; and
(3) Not be a Federal entity or Federal
employee acting within the scope of
their employment.
III. Rules
The complete rules for the Vascular
Tissue Challenge can be found at:
https://www.neworgan.org/vtcprize.php.
Cheryl Parker,
NASA Federal Register Liaison Officer.
[FR Doc. 2016–13795 Filed 6–10–16; 8:45 am]
BILLING CODE 7510–13–P
SUPPLEMENTARY INFORMATION:
[FR Doc. 2016–13818 Filed 6–10–16; 8:45 am]
ACTION:
38225
Competitors will be asked to produce
an in-vitro vascularized tissue that is ≥
1 centimeter in thickness in all
dimensions at the launch of the trial and
maintains ≥85% survival of the required
parenchymal cells throughout a 30-day
period. Tissues must provide adequate
blood perfusion without uncontrolled
leakage into the bulk tissue to maintain
metabolic functionality similar to their
in-vivo native cells. Histological
measurement of the quality and amount
of functional performance will be
required to determine survival of
parenchymal tissue. Teams must
demonstrate 3 successful trials with at
least a 75% trial success rate to win an
award. In addition to the in-vitro trials,
teams must also submit a Spaceflight
Experiment Concept that details how
they would further advance some aspect
of their tissue vascularization research
through a microgravity experiment that
could be conducted in the U.S. National
Laboratory (ISS–NL) onboard the
International Space Station.
PO 00000
Frm 00099
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TIME AND DATE:
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[Federal Register Volume 81, Number 113 (Monday, June 13, 2016)]
[Notices]
[Page 38225]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2016-13795]
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NATIONAL AERONAUTICS AND SPACE ADMINISTRATION
Centennial Challenges Vascular Tissue Challenge
AGENCY: National Aeronautics and Space Administration (NASA).
(16-041)
ACTION: Notice.
-----------------------------------------------------------------------
SUMMARY: This notice is issued in accordance with 51 U.S.C. 20144(c).
The Vascular Tissue Challenge is open and teams that wish to compete
may now register. Centennial Challenges is a program of prize
competitions to stimulate innovation in technologies of interest and
value to NASA and the nation. The Vascular Tissue Challenge is a prize
competition with a $500,000 prize purse for teams that can successfully
create thick, human vascularized organ tissue in an in vitro
environment while maintaining metabolic functionality similar to their
in vivo functionality throughout a 30-day survival period. NASA is
providing the prize purse. The Methuselah Foundation's New Organ
Alliance is the Allied Organization managing the competition.
DATES: This is a ``first to demonstrate'' competition. Teams may submit
their intent to compete beginning June 13, 2016 and the competition
will remain open until the requirements of the rules are met and a
winner is announced or until the Challenge Deadline of September 30th,
2019.
ADDRESSES: The Vascular Tissue Challenge will be conducted and judged
at the laboratory facilities of the participants.
FOR FURTHER INFORMATION CONTACT: To register for or get additional
information regarding the Vascular Tissue Challenge, please visit:
https://www.neworgan.org/vtc-prize.php.
For general information on the NASA Centennial Challenges Program
please visit: https://www.nasa.gov/challenges. General questions and
comments regarding the program should be addressed to Monsi Roman,
Centennial Challenges Program, NASA Marshall Space Flight Center
Huntsville, AL 35812. Email address: hq-stmd-centennialchallenges@mail.nasa.gov.
SUPPLEMENTARY INFORMATION:
Summary
Competitors will be asked to produce an in-vitro vascularized
tissue that is = 1 centimeter in thickness in all dimensions
at the launch of the trial and maintains =85% survival of
the required parenchymal cells throughout a 30-day period. Tissues must
provide adequate blood perfusion without uncontrolled leakage into the
bulk tissue to maintain metabolic functionality similar to their in-
vivo native cells. Histological measurement of the quality and amount
of functional performance will be required to determine survival of
parenchymal tissue. Teams must demonstrate 3 successful trials with at
least a 75% trial success rate to win an award. In addition to the in-
vitro trials, teams must also submit a Spaceflight Experiment Concept
that details how they would further advance some aspect of their tissue
vascularization research through a microgravity experiment that could
be conducted in the U.S. National Laboratory (ISS-NL) onboard the
International Space Station.
I. Prize Amounts
The total Vascular Tissue Challenge prize purse is $500,000 (five
hundred thousand U.S. dollars). First place will receive $300,000
(three hundred thousand U.S. dollars). Two runners-up may be awarded
$100,000 (one hundred thousand U.S. dollars) each. Entries must meet
specific requirements detailed in the Rules to be eligible for prize
awards.
II. Eligibility
To be eligible to win a prize, competitors must;
(1) Register and comply with all requirements in the rules and Team
Agreement;
(2) In the case of a private entity, shall be incorporated in and
maintain a primary place of business in the United States, and in the
case of an individual, whether participating singly or in a group,
shall be a citizen or permanent resident of the United States; and
(3) Not be a Federal entity or Federal employee acting within the
scope of their employment.
III. Rules
The complete rules for the Vascular Tissue Challenge can be found
at: https://www.neworgan.org/vtc-prize.php.
Cheryl Parker,
NASA Federal Register Liaison Officer.
[FR Doc. 2016-13795 Filed 6-10-16; 8:45 am]
BILLING CODE 7510-13-P