Request for Nominations for Peer Reviewers for EPA's Draft Biologically Based Dose-Response (BBDR) Model for Perchlorate, Draft Model Support Document and Draft Approach for Deriving a Maximum Contaminant Level Goal (MCLG) for Perchlorate in Drinking Water, 35760-35761 [2016-12724]
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Federal Register / Vol. 81, No. 107 / Friday, June 3, 2016 / Notices
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Dated: May 26, 2016.
Nathaniel J. Davis, Sr.,
Deputy Secretary.
[FR Doc. 2016–13064 Filed 6–2–16; 8:45 am]
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ENVIRONMENTAL PROTECTION
AGENCY
[EPA–HQ–OW–2009–0297; FRL–9947–20–
OW]
Request for Nominations for Peer
Reviewers for EPA’s Draft Biologically
Based Dose-Response (BBDR) Model
for Perchlorate, Draft Model Support
Document and Draft Approach for
Deriving a Maximum Contaminant
Level Goal (MCLG) for Perchlorate in
Drinking Water
Environmental Protection
Agency (EPA).
ACTION: Request for nominations for
peer reviewers.
AGENCY:
The Environmental Protection
Agency (EPA) is expanding the scope of
the request for nominations announced
in the Federal Register on March 1,
2016. Requested nominations are for an
external peer review of the draft
Biologically Based Dose-Response
model and the draft model support
document for perchlorate in drinking
water. The expanded scope will include
the review of the application of the draft
Biologically Based Dose-Response
Model to develop a perchlorate
maximum contaminant level goal. EPA
is combining the two panels to achieve
efficiency and transparency in
evaluating the development and
application of key scientific products for
analyzing perchlorate in drinking water.
EPA invites the public to nominate
scientific experts for the peer review.
Persons nominated during the previous
nomination period requested in the
March 1, 2016, Federal Register notice
do not need to be renominated under
this notice and will be considered for
selection for the interim and final list of
peer reviewers.
DATES: The nomination period for
scientific experts begins on June 3, 2016
and ends on July 5, 2016.
ADDRESSES: Any interested person or
organization may nominate scientific
experts to be considered as peer
reviewers. Nominations should be
submitted in time to arrive no later than
July 5, 2016. Self-nominations will also
be accepted. Nominations should be
submitted to the EPA contractor, Versar,
Inc., using the following email address:
perchlorate@versar.com (the subject line
should read: BBDR Model Peer Review
and Peer Review of Approach for
Deriving a Perchlorate MCLG).
Nominations will also be accepted via
the U.S. Postal Service mail or by an
overnight/priority mail service. Mailed
nominations should be addressed to
Versar, Inc., 6850 Versar Center,
SUMMARY:
PO 00000
Frm 00028
Fmt 4703
Sfmt 4703
Springfield, VA 22151 (Attention: David
Bottimore). Nominations should include
all nominee information outlined in
section II of the SUPPLEMENTARY
INFORMATION section of this document.
FOR FURTHER INFORMATION CONTACT:
Questions concerning the nomination
process should be directed to the EPA
contractor, Versar, Inc., at 6850 Versar
Center, Springfield, VA 22151; by email
to perchlorate@versar.com (the subject
line should read: BBDR Model Peer
Review and Peer Review of Approach
for Deriving a Perchlorate MCLG); or by
phone: (703) 642–6815 (ask for David
Bottimore). For additional information
concerning the draft Biologically Based
Dose-Response Model, the draft Model
Support Document and the draft
approach for deriving a perchlorate
MCLG, please contact Russ Perkinson at
the U.S. Environmental Protection
Agency, Office of Ground Water and
Drinking Water, Standards and Risk
Management Division, (Mail Code
4607M), 1200 Pennsylvania Avenue
NW., Washington, DC 20460; telephone:
202–564–4901; or email:
perkinson.russ@epa.gov.
SUPPLEMENTARY INFORMATION:
I. Information on the Draft Biologically
Based Dose-Response (BBDR) Model,
the Draft Model Support Document for
Perchlorate and the Draft Approach for
Deriving a Perchlorate Maximum
Contaminant Level Goal (MCLG)
EPA has begun the process for
developing a National Primary Drinking
Water Regulation (NPDWR) for
Perchlorate in accordance with the
requirements under the Safe Drinking
Water Act (SDWA). Among these
requirements are that the agency must
request comment from EPA’s Science
Advisory Board (SAB) prior to proposal
of an MCLG and a NPDWR. 42 U.S.C.
1412(e). For additional background
information, refer to the March 1, 2016,
Federal Register notice (81 FR 10617).
Based on the SAB’s
recommendations, EPA, with
contributions from Food and Drug
Administration (FDA) scientists,
developed a draft BBDR model to
determine under what conditions of
iodine nutrition and exposure to
perchlorate across sensitive life stages
low serum free and total thyroxine
would result. The draft BBDR model
integrates physiologically-based
pharmacokinetic models for perchlorate
with iodine models for thyroid
hormones in formula-fed and nursing
infants, as well as lactating women. The
draft model predicts the effects of
perchlorate on serum thyroid hormone
concentrations in infants exposed via
E:\FR\FM\03JNN1.SGM
03JNN1
Federal Register / Vol. 81, No. 107 / Friday, June 3, 2016 / Notices
mstockstill on DSK3G9T082PROD with NOTICES
ingestion of formula mixed with
contaminated drinking water or breast
milk.
EPA is considering deriving a
perchlorate MCLG by linking BBDR
model output to alterations in thyroid
hormone status that result in alterations
in neurodevelopment. The draft
approach for deriving a perchlorate
MCLG outlines an assessment of the
literature linking alterations in thyroid
hormone status to alterations in
neurodevelopment. Based on the results
of this literature review, the report
describes potential approaches to set the
MCLG based on the availability of the
current literature and the output of the
BBDR model, predicting the effects of
perchlorate on serum thyroid hormone
concentrations in infants exposed via
ingestion of formula mixed with
contaminated drinking water or breast
milk (see 81 FR 10617, March 1, 2016).
The draft approach will be
approximately 100 pages in length with
approximately 7–10 figures and 10–15
tables. The draft approach describes
application of the BBDR model to the
development of a perchlorate MCLG and
the appropriateness of the process under
SDWA guidelines.
EPA anticipates releasing the draft
BBDR model, draft model support
document, and draft approach for peer
review and public comment in the near
future (the exact date to be determined).
II. How To Submit Nominations for
Peer Reviewers
Expanded Expertise Sought: EPA is
seeking candidates who are nationally
and/or internationally recognized
scientific experts to serve as external
peer reviewers for the draft BBDR
model, the draft model support
document, and the draft approach to
derive a perchlorate MCLG. Nominees
should possess and demonstrate
background knowledge and experience
in one or more of the following areas of
risk assessment to include: An
understanding of thyroid function
(preferably in the sensitive life stages of
interest), the importance of maternal
thyroid hormone homeostasis in each
stage of gestation, hypothyroxinemia,
neurodevelopmental assessment indices
for young children including the
Bayley’s Scale, the toxicity of
perchlorate, epidemiological assessment
techniques, and statistics.
Expanded Selection Criteria:
Selection criteria for individuals
nominated to serve as external peer
reviewers of the draft BBDR model, draft
model support document, and draft
approach to derive an MCLG for
perchlorate include the following: (1)
Demonstrated expertise through
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21:20 Jun 02, 2016
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relevant peer reviewed publications, (2)
professional accomplishments and
recognition by professional societies, (3)
demonstrated ability to work
constructively and effectively in a
committee setting, (4) absence of
financial conflicts of interest, (5) no
actual conflicts of interest or the
appearance of lack of impartiality, (6)
willingness to commit adequate time for
the thorough review of the draft BBDR
model, the draft model support
document and the draft approach for
deriving a perchlorate MCLG,
commencing approximately during the
summer of 2016 (exact date to be
determined), and (7) availability to
participate in person in a two-day peer
review meeting in the Washington, DC
metro area, projected to occur during
the fall of 2016 (exact date will be
published in the Federal Register at
least 30 days prior to the external peer
review meeting). Further logistical
information regarding the external peer
review meeting will be announced at a
later date in the Federal Register.
Expanded Required Nominee
Information: To receive full
consideration, the following information
should be submitted to Versar
(perchlorate@versar.com) (the subject
line should read: BBDR Model Peer
Review and Peer Review of Approach
for Deriving a Perchlorate MCLG): (1)
Contact information for the person
making the nomination; (2) contact
information for the nominee; (3) the
disciplinary and specific areas of
expertise of the nominee; (4) the
nominee’s curriculum vitae; and (5) a
biographical sketch of the nominee
indicating current position, educational
background, past and current research
activities, recent service on other
advisory committees, peer review
panels, editorial boards or professional
organizations, sources of recent grant
and/or contract support and other
comments on the relevance of the
nominee’s expertise to this peer review
topic. Compensation for non-federal
peer reviewers will be provided by
Versar.
Expanded Selection Process: EPA’s
contractor, Versar, will notify
candidates of selection or non-selection.
Versar may also conduct an
independent search for candidates to
assemble a balanced group representing
the expertise needed to fully evaluate
EPA’s draft BBDR model, draft model
support document for perchlorate, and
draft approach for deriving a perchlorate
MCLG. The contractor will consider and
screen all candidates against the criteria
previously listed. Following the
screening process, the contractor will
narrow the list of potential reviewers to
PO 00000
Frm 00029
Fmt 4703
Sfmt 4703
35761
approximately 12–18 interim
candidates. Prior to selecting the final
peer reviewers, a Federal Register
notice will be published (exact date to
be determined) to solicit comments on
the interim list of candidates. In that
notice, the public will be requested to
provide relevant information or
documentation on the nominees within
30 days of the announcement of the
interim list of candidates. Once the
contractor has considered the public
comments on the interim list of
candidates, the contractor will select the
final list of peer reviewers based on
who, collectively, will best provide
expertise spanning the disciplines listed
above and (to the extent feasible) best
provide a balance of perspectives.
Dated: May 23, 2016.
Joel Beauvais,
Deputy Assistant Administrator.
[FR Doc. 2016–12724 Filed 6–2–16; 8:45 am]
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AGENCY
[ER–FRL–9027–4]
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Notice of Availability
Responsible Agency: Office of Federal
Activities, General Information (202)
564–7146 or https://www.epa.gov/nepa.
Weekly receipt of Environmental Impact
Statements (EISs)
Filed 05/23/2016 Through 05/27/2016
Pursuant to 40 CFR 1506.9.
Notice
Section 309(a) of the Clean Air Act
requires that EPA make public its
comments on EISs issued by other
Federal agencies. EPA’s comment letters
on EISs are available at: https://
www.epa.gov/compliance/nepa/
eisdata.html.
EIS No. 20160112, Draft, USFS, MT,
Galton Vegetation Management,
Comment Period Ends: 07/25/2016,
Contact: Ron Komac 406–296–2536
x7130.
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Flathead National Forest Plan
Revision and Northern Continental
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E:\FR\FM\03JNN1.SGM
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Agencies
[Federal Register Volume 81, Number 107 (Friday, June 3, 2016)]
[Notices]
[Pages 35760-35761]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2016-12724]
=======================================================================
-----------------------------------------------------------------------
ENVIRONMENTAL PROTECTION AGENCY
[EPA-HQ-OW-2009-0297; FRL-9947-20-OW]
Request for Nominations for Peer Reviewers for EPA's Draft
Biologically Based Dose-Response (BBDR) Model for Perchlorate, Draft
Model Support Document and Draft Approach for Deriving a Maximum
Contaminant Level Goal (MCLG) for Perchlorate in Drinking Water
AGENCY: Environmental Protection Agency (EPA).
ACTION: Request for nominations for peer reviewers.
-----------------------------------------------------------------------
SUMMARY: The Environmental Protection Agency (EPA) is expanding the
scope of the request for nominations announced in the Federal Register
on March 1, 2016. Requested nominations are for an external peer review
of the draft Biologically Based Dose-Response model and the draft model
support document for perchlorate in drinking water. The expanded scope
will include the review of the application of the draft Biologically
Based Dose-Response Model to develop a perchlorate maximum contaminant
level goal. EPA is combining the two panels to achieve efficiency and
transparency in evaluating the development and application of key
scientific products for analyzing perchlorate in drinking water. EPA
invites the public to nominate scientific experts for the peer review.
Persons nominated during the previous nomination period requested in
the March 1, 2016, Federal Register notice do not need to be
renominated under this notice and will be considered for selection for
the interim and final list of peer reviewers.
DATES: The nomination period for scientific experts begins on June 3,
2016 and ends on July 5, 2016.
ADDRESSES: Any interested person or organization may nominate
scientific experts to be considered as peer reviewers. Nominations
should be submitted in time to arrive no later than July 5, 2016. Self-
nominations will also be accepted. Nominations should be submitted to
the EPA contractor, Versar, Inc., using the following email address:
perchlorate@versar.com (the subject line should read: BBDR Model Peer
Review and Peer Review of Approach for Deriving a Perchlorate MCLG).
Nominations will also be accepted via the U.S. Postal Service mail or
by an overnight/priority mail service. Mailed nominations should be
addressed to Versar, Inc., 6850 Versar Center, Springfield, VA 22151
(Attention: David Bottimore). Nominations should include all nominee
information outlined in section II of the SUPPLEMENTARY INFORMATION
section of this document.
FOR FURTHER INFORMATION CONTACT: Questions concerning the nomination
process should be directed to the EPA contractor, Versar, Inc., at 6850
Versar Center, Springfield, VA 22151; by email to
perchlorate@versar.com (the subject line should read: BBDR Model Peer
Review and Peer Review of Approach for Deriving a Perchlorate MCLG); or
by phone: (703) 642-6815 (ask for David Bottimore). For additional
information concerning the draft Biologically Based Dose-Response
Model, the draft Model Support Document and the draft approach for
deriving a perchlorate MCLG, please contact Russ Perkinson at the U.S.
Environmental Protection Agency, Office of Ground Water and Drinking
Water, Standards and Risk Management Division, (Mail Code 4607M), 1200
Pennsylvania Avenue NW., Washington, DC 20460; telephone: 202-564-4901;
or email: perkinson.russ@epa.gov.
SUPPLEMENTARY INFORMATION:
I. Information on the Draft Biologically Based Dose-Response (BBDR)
Model, the Draft Model Support Document for Perchlorate and the Draft
Approach for Deriving a Perchlorate Maximum Contaminant Level Goal
(MCLG)
EPA has begun the process for developing a National Primary
Drinking Water Regulation (NPDWR) for Perchlorate in accordance with
the requirements under the Safe Drinking Water Act (SDWA). Among these
requirements are that the agency must request comment from EPA's
Science Advisory Board (SAB) prior to proposal of an MCLG and a NPDWR.
42 U.S.C. 1412(e). For additional background information, refer to the
March 1, 2016, Federal Register notice (81 FR 10617).
Based on the SAB's recommendations, EPA, with contributions from
Food and Drug Administration (FDA) scientists, developed a draft BBDR
model to determine under what conditions of iodine nutrition and
exposure to perchlorate across sensitive life stages low serum free and
total thyroxine would result. The draft BBDR model integrates
physiologically-based pharmacokinetic models for perchlorate with
iodine models for thyroid hormones in formula-fed and nursing infants,
as well as lactating women. The draft model predicts the effects of
perchlorate on serum thyroid hormone concentrations in infants exposed
via
[[Page 35761]]
ingestion of formula mixed with contaminated drinking water or breast
milk.
EPA is considering deriving a perchlorate MCLG by linking BBDR
model output to alterations in thyroid hormone status that result in
alterations in neurodevelopment. The draft approach for deriving a
perchlorate MCLG outlines an assessment of the literature linking
alterations in thyroid hormone status to alterations in
neurodevelopment. Based on the results of this literature review, the
report describes potential approaches to set the MCLG based on the
availability of the current literature and the output of the BBDR
model, predicting the effects of perchlorate on serum thyroid hormone
concentrations in infants exposed via ingestion of formula mixed with
contaminated drinking water or breast milk (see 81 FR 10617, March 1,
2016). The draft approach will be approximately 100 pages in length
with approximately 7-10 figures and 10-15 tables. The draft approach
describes application of the BBDR model to the development of a
perchlorate MCLG and the appropriateness of the process under SDWA
guidelines.
EPA anticipates releasing the draft BBDR model, draft model support
document, and draft approach for peer review and public comment in the
near future (the exact date to be determined).
II. How To Submit Nominations for Peer Reviewers
Expanded Expertise Sought: EPA is seeking candidates who are
nationally and/or internationally recognized scientific experts to
serve as external peer reviewers for the draft BBDR model, the draft
model support document, and the draft approach to derive a perchlorate
MCLG. Nominees should possess and demonstrate background knowledge and
experience in one or more of the following areas of risk assessment to
include: An understanding of thyroid function (preferably in the
sensitive life stages of interest), the importance of maternal thyroid
hormone homeostasis in each stage of gestation, hypothyroxinemia,
neurodevelopmental assessment indices for young children including the
Bayley's Scale, the toxicity of perchlorate, epidemiological assessment
techniques, and statistics.
Expanded Selection Criteria: Selection criteria for individuals
nominated to serve as external peer reviewers of the draft BBDR model,
draft model support document, and draft approach to derive an MCLG for
perchlorate include the following: (1) Demonstrated expertise through
relevant peer reviewed publications, (2) professional accomplishments
and recognition by professional societies, (3) demonstrated ability to
work constructively and effectively in a committee setting, (4) absence
of financial conflicts of interest, (5) no actual conflicts of interest
or the appearance of lack of impartiality, (6) willingness to commit
adequate time for the thorough review of the draft BBDR model, the
draft model support document and the draft approach for deriving a
perchlorate MCLG, commencing approximately during the summer of 2016
(exact date to be determined), and (7) availability to participate in
person in a two-day peer review meeting in the Washington, DC metro
area, projected to occur during the fall of 2016 (exact date will be
published in the Federal Register at least 30 days prior to the
external peer review meeting). Further logistical information regarding
the external peer review meeting will be announced at a later date in
the Federal Register.
Expanded Required Nominee Information: To receive full
consideration, the following information should be submitted to Versar
(perchlorate@versar.com) (the subject line should read: BBDR Model Peer
Review and Peer Review of Approach for Deriving a Perchlorate MCLG):
(1) Contact information for the person making the nomination; (2)
contact information for the nominee; (3) the disciplinary and specific
areas of expertise of the nominee; (4) the nominee's curriculum vitae;
and (5) a biographical sketch of the nominee indicating current
position, educational background, past and current research activities,
recent service on other advisory committees, peer review panels,
editorial boards or professional organizations, sources of recent grant
and/or contract support and other comments on the relevance of the
nominee's expertise to this peer review topic. Compensation for non-
federal peer reviewers will be provided by Versar.
Expanded Selection Process: EPA's contractor, Versar, will notify
candidates of selection or non-selection. Versar may also conduct an
independent search for candidates to assemble a balanced group
representing the expertise needed to fully evaluate EPA's draft BBDR
model, draft model support document for perchlorate, and draft approach
for deriving a perchlorate MCLG. The contractor will consider and
screen all candidates against the criteria previously listed. Following
the screening process, the contractor will narrow the list of potential
reviewers to approximately 12-18 interim candidates. Prior to selecting
the final peer reviewers, a Federal Register notice will be published
(exact date to be determined) to solicit comments on the interim list
of candidates. In that notice, the public will be requested to provide
relevant information or documentation on the nominees within 30 days of
the announcement of the interim list of candidates. Once the contractor
has considered the public comments on the interim list of candidates,
the contractor will select the final list of peer reviewers based on
who, collectively, will best provide expertise spanning the disciplines
listed above and (to the extent feasible) best provide a balance of
perspectives.
Dated: May 23, 2016.
Joel Beauvais,
Deputy Assistant Administrator.
[FR Doc. 2016-12724 Filed 6-2-16; 8:45 am]
BILLING CODE 6560-50-P