Breast Cancer Fund, Center for Environmental Health, Center for Food Safety, Center for Science in the Public Interest, Clean Water Action, Consumer Federation of America, Earthjustice, Environmental Defense Fund, Improving Kids' Environment, Learning Disabilities Association of America, and Natural Resources Defense Council; Filing of Food Additive Petition, 31877-31879 [2016-11866]
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Federal Register / Vol. 81, No. 98 / Friday, May 20, 2016 / Proposed Rules
(ii) For the final results of an
administrative review, new shipper
review, changed circumstances review,
or section 762 review, 30 days after the
date of publication of the preliminary
results of review, unless the Secretary
alters the time limit; or
(iii) For the final results of an
expedited sunset review, expedited
antidumping or countervailing duty
review, Article 8 violation review,
Article 4/Article 7 review, or section
753 review, a date specified by the
Secretary.
(2) The case brief must present all
arguments that continue in the
submitter’s view to be relevant to the
Secretary’s final determination or final
results, including any arguments
presented before the date of publication
of the preliminary determination or
preliminary results. As part of the case
brief, parties are encouraged to provide
a summary of the arguments not to
exceed five pages and a table of statutes,
regulations, and cases cited.
(d) Rebuttal brief. (1) Any interested
party or U.S. Government agency may
submit a ‘‘rebuttal brief’’ within five
days after the time limit for filing the
case brief, unless the Secretary alters
this time limit.
(2) The rebuttal brief may respond
only to arguments raised in case briefs
and should identify the arguments to
which it is responding. As part of the
rebuttal brief, parties are encouraged to
provide a summary of the arguments not
to exceed five pages and a table of
statutes, regulations, and cases cited.
(e) Word limits. (1) Except with the
consent of Enforcement & Compliance
for good cause, each party shall use no
more than 25,000 words total between
its case and rebuttal briefs. The
allocation of the 25,000 words between
case and rebuttal briefs is left to each
party. All attachments to such briefs,
headings, footnotes, endnotes, and
quotations shall be included in the word
limitation. The summary of arguments
and the table of statutes, regulations and
cases cited referenced in paragraphs
(c)(2) and (d)(2) of this section shall not
be included in the word limitation.
(2) The case brief, if any, shall contain
a certification by the party or its
representative indicating the number of
words in the brief and the number of
words available for the rebuttal brief.
The rebuttal brief, if any, shall contain
a certification by the party or its
representative indicating the number of
words in the brief and certifying that the
total word limit of 25,000 has not been
exceeded in the party’s combined case
and rebuttal brief word limit. The party
filing the certification may rely on the
word count of the software program
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used to prepare the brief. Briefs in
excess of the word limitation shall be
rejected and shall be considered
untimely. Challenges to opposing
party’s word count must be filed with
the agency within 48 hours of the filing
of the case or reply brief and
accompanying certifications or the
challenge will not be considered. If a
person has designated an agent to
receive service that is located outside
the United States, and served briefs by
first class airmail in accordance with 19
CFR 351.303(f)(3)(i), the agency will
consider on a case-by-case basis the
time allowed to that person to challenge
a party’s word count.
(f) Comments on adequacy of
response and appropriateness of
expedited sunset review—(1) In general.
Where the Secretary determines that
respondent interested parties provided
inadequate response to a notice of
initiation (see § 351.218(e)(1)(ii)) and
has notified the International Trade
Commission as such under
§ 351.218(e)(1)(ii)(C), interested parties
(and industrial users and consumer
organizations) that submitted a
complete substantive response to the
notice of initiation under § 351.218(d)(3)
may file comments on whether an
expedited sunset review under section
751(c)(3)(B) of the Act and
§ 351.218(e)(1)(ii)(B) or (C) is
appropriate based on the adequacy of
responses to the notice of initiation.
These comments may not include any
new factual information or evidence
(such as supplementation of a
substantive response to the notice of
initiation) and are limited to five pages.
(2) Time limit for filing comments.
Comments on adequacy of response and
appropriateness of expedited sunset
review must be filed not later than 70
days after the date publication in the
Federal Register of the notice of
initiation.
[FR Doc. 2016–11864 Filed 5–19–16; 8:45 am]
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31877
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Food and Drug Administration
21 CFR Parts 175, 176, 177, and 178
[Docket No. FDA–2016–F–1253]
Breast Cancer Fund, Center for
Environmental Health, Center for Food
Safety, Center for Science in the Public
Interest, Clean Water Action,
Consumer Federation of America,
Earthjustice, Environmental Defense
Fund, Improving Kids’ Environment,
Learning Disabilities Association of
America, and Natural Resources
Defense Council; Filing of Food
Additive Petition
AGENCY:
Food and Drug Administration,
HHS.
ACTION:
Notice of petition.
The Food and Drug
Administration (FDA or we) is
announcing that we have filed a
petition, submitted by Breast Cancer
Fund, Center for Environmental Health,
Center for Food Safety, Center for
Science in the Public Interest, Clean
Water Action, Consumer Federation of
America, Earthjustice, Environmental
Defense Fund, Improving Kids’
Environment, Learning Disabilities
Association of America, and Natural
Resources Defense Council proposing
that we amend and/or revoke specified
regulations to no longer provide for the
food contact use of specified orthophthalates.
SUMMARY:
The food additive petition was
filed on April 12, 2016. Submit either
electronic or written comments by July
19, 2016.
ADDRESSES: You may submit comments
as follows:
DATES:
Electronic Submissions
Submit electronic comments in the
following way:
• Federal eRulemaking Portal: https://
www.regulations.gov. Follow the
instructions for submitting comments.
Comments submitted electronically,
including attachments, to https://
www.regulations.gov will be posted to
the docket unchanged. Because your
comment will be made public, you are
solely responsible for ensuring that your
comment does not include any
confidential information that you or a
third party may not wish to be posted,
such as medical information, your or
anyone else’s Social Security number, or
confidential business information, such
as a manufacturing process. Please note
that if you include your name, contact
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information, or other information that
identifies you in the body of your
comments, that information will be
posted on https://www.regulations.gov.
• If you want to submit a comment
with confidential information that you
do not wish to be made available to the
public, submit the comment as a
written/paper submission and in the
manner detailed (see ‘‘Written/Paper
Submissions’’ and ‘‘Instructions’’).
Written/Paper Submissions
Submit written/paper submissions as
follows:
• Mail/Hand delivery/Courier (for
written/paper submissions): Division of
Dockets Management (HFA–305), Food
and Drug Administration, 5630 Fishers
Lane, Rm. 1061, Rockville, MD 20852.
• For written/paper comments
submitted to the Division of Dockets
Management, FDA will post your
comment, as well as any attachments,
except for information submitted,
marked and identified, as confidential,
if submitted as detailed in
‘‘Instructions.’’
Instructions: All submissions received
must include the Docket No. FDA–
2016–F–1253 for ‘‘Breast Cancer Fund,
Center for Environmental Health, Center
for Food Safety, Center for Science In
The Public Interest, Clean Water Action,
Consumer Federation of America,
Earthjustice, Environmental Defense
Fund, Improving Kids’ Environment,
Learning Disabilities Association of
America, and Natural Resources Defense
Council; Filing of Food Additive
Petition.’’ Received comments will be
placed in the docket and, except for
those submitted as ‘‘Confidential
Submissions,’’ publicly viewable at
https://www.regulations.gov or at the
Division of Dockets Management
between 9 a.m. and 4 p.m., Monday
through Friday.
• Confidential Submissions—To
submit a comment with confidential
information that you do not wish to be
made publicly available, submit your
comments only as a written/paper
submission. You should submit two
copies total. One copy will include the
information you claim to be confidential
with a heading or cover note that states
‘‘THIS DOCUMENT CONTAINS
CONFIDENTIAL INFORMATION.’’ The
Agency will review this copy, including
the claimed confidential information, in
its consideration of comments. The
second copy, which will have the
claimed confidential information
redacted/blacked out, will be available
for public viewing and posted on https://
www.regulations.gov. Submit both
copies to the Division of Dockets
Management. If you do not wish your
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name and contact information to be
made publicly available, you can
provide this information on the cover
sheet and not in the body of your
comments and you must identify this
information as ‘‘confidential.’’ Any
information marked as ‘‘confidential’’
will not be disclosed except in
accordance with 21 CFR 10.20 and other
applicable disclosure law. For more
information about FDA’s posting of
comments to public dockets, see 80 FR
56469, September 18, 2015, or access
the information at: https://www.fda.gov/
regulatoryinformation/dockets/
default.htm.
Docket: For access to the docket to
read background documents or the
electronic and written/paper comments
received, go to https://
www.regulations.gov and insert the
docket number, found in brackets in the
heading of this document, into the
‘‘Search’’ box and follow the prompts
and/or go to the Division of Dockets
Management, 5630 Fishers Lane, Rm.
1061, Rockville, MD 20852.
FOR FURTHER INFORMATION CONTACT:
Kelly Randolph, Center for Food Safety
and Applied Nutrition (HFS–275), Food
and Drug Administration, 5100 Paint
Branch Pkwy., College Park, MD 20740–
3835, 240–402–1188.
SUPPLEMENTARY INFORMATION:
I. Background
Under section 409(b)(5) of the Federal
Food, Drug, and Cosmetic Act (the
FD&C Act) (21 U.S.C. 348(b)(5)), we are
giving notice that we have filed a food
additive petition (FAP 6B4815),
submitted by Breast Cancer Fund,
Center for Science in the Public Interest,
Center for Environmental Health, Center
for Food Safety, Clean Water Action,
Consumer Federation of America,
Earthjustice, Environmental Defense
Fund, Improving Kids’ Environment,
Learning Disabilities Association of
America, and Natural Resources Defense
Council, c/o Mr. Thomas Neltner, 1875
Connecticut Ave. NW., Suite 600,
Washington, DC 20009. The submission
proposes that we amend and/or revoke
specified food additive regulations
under 21 CFR parts 175, 176, 177, and
178 to no longer provide for the food
contact use of specified orthophthalates. We have filed this portion of
the submission as a food additive
petition. The submission also requests
that we amend our regulations in 21
CFR part 181 related to prior-sanctioned
uses of specified ortho-phthalates and
issue a new regulation in 21 CFR part
189 prohibiting the use of eight specific
ortho-phthalates. We have declined to
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file these portions of the submission as
a food additive petition.
II. Amendment of 21 CFR Parts 175,
176, 177, and 178
In accordance with the procedures for
amending or revoking a food additive
regulation in § 171.130 (21 CFR
171.130), the petition asks us to amend
parts 175, 176, 177, and 178 to no longer
provide for the food contact use of
certain specified ortho-phthalates. The
specified ortho-phthalates and
corresponding regulations in parts 175,
176, 177, and 178 are as follows:
§ 175.105 Adhesives
Butyl benzyl phthalate (CAS No. 85–
68–7), Butyldecyl phthalate (CAS No.
89–19–0), Butyloctyl phthalate (CAS
No. 84–78–6), Butyl phthalate butyl
glycolate (CAS No. 85–70–1),
Di(butoxyethyl) phthalate (CAS No.117–
83–9), Dibutyl phthalate (CAS No. 84–
74–2), Dicyclohexyl phthalate (CAS No.
84–61–7), Di(2ethylhexyl)hexahydrophthalate, Di(2ethylhexyl)phthalate (CAS No. 117–81–
7), Diethyl phthalate (CAS No. 84–66–
2), Dihexyl phthalate (CAS No. 84–75–
3), Dihydroabietylphthalate (CAS No.
26760–71–4), Diisobutyl phthalate (CAS
No. 84–69–5), Diisodecyl phthalate
(CAS No. 26761–40–0), Diisooctyl
phthalate (CAS No. 27554–26–3),
Dimethyl phthalate (CAS No. 131–11–
3), Dioctyl phthalate (CAS No. 117–84–
0), Diphenyl phthalate (CAS No. 84–62–
8), Ethyl phthalyl ethyl glycolate (CAS
No. 84–72–0), Methyl phthalyl ethyl
glycolate (CAS No. 85–71–2),
Octyldecyl phthalate (CAS No. 119–07–
3), and Diallyl phthalate (CAS No. 131–
17–9).
§ 175.300 Resinous and Polymeric
Coatings
Dibutyl phthalate (CAS No. 84–74–2),
Diethyl phthalate (CAS No. 84–66–2),
Diisooctyl phthalate (CAS No. 27554–
26–3), Di(2-ethylhexyl) phthalate (CAS
No. 117–81–7), and Diisodecyl
phthalate (CAS No. 26761–40–0).
§ 175.320 Resinous and Polymeric
Coatings for Polyolefin Films
Butyl phthalyl butyl glycolate (CAS
No. 85–70–1), Diethyl phthalate (CAS
No. 84–66–2), and Ethyl phthalyl ethyl
glycolate (CAS No. 84–72–0).
§ 176.170 Components of Paper and
Paperboard in Contact With Aqueous
and Fatty Foods
Butylbenzyl phthalate (CAS No. 85–
68–7), Dibutyl phthalate (CAS No. 84–
74–2), Dicyclohexyl phthalate (CAS No.
84–61–7), and Diallyl phthalate (CAS
No. 131–17–9).
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§ 176.180 Components of Paper and
Paperboard in Contact With Dry Food
Butyl benzyl phthalate (CAS No. 85–
68–7) and Diallyl phthalate (CAS No.
131–17–9).
§ 176.210 Defoaming Agents Used in
the Manufacture of Paper and
Paperboard
Di(2-ethylhexyl) phthalate (CAS No.
117–81–7).
§ 176.300
Slimicides
Dibutyl phthalate (CAS No. 84–74–2),
Didecyl phthalate (CAS No. 84–77–5),
and Dodecyl phthalate (CAS No. 21577–
80–0).
§ 177.1010 Acrylic and Modified
Acrylic Plastics, Semirigid and Rigid
Di(2-ethylhexyl) phthalate (CAS No.
117–81–7) and Dimethyl phthalate (CAS
No. 131–11–3).
§ 177.1200
Cellophane
Castor oil phthalate with adipic acid
and fumaric acid diethylene glycol
polyester (CAS No. 68650–73–7), Castor
oil phthalate, hydrogentated (FDA No.
977037–59–4), Dibutylphthalate (CAS
No. 84–74–2), Dicyclohexyl phthalate
(CAS No. 84–61–7), Di(2-ethylhexy)
phthalate (CAS No. 117–81–7),
Diisobutyl phthalate (CAS No. 84–69–
5), and Dimethylcyclohexyl phthalate
(CAS No. 1322–94–7).
§ 177.1210 Closures With Sealing
Gaskets for Food Containers
Diisodecyl phthalate (CAS No. 26761–
40–0).
§ 177.1460 Melamine-Formaldehyde
Resins in Molded Articles
Dioctyl phthalate (CAS No. 117–84–
0).
§ 177.1590
Polyester Elastomers
Dimethyl orthophthalate (CAS No.
131–11–3).
§ 177.2420
Linked
Polyester Resins, Cross-
Butyl benzyl phthalate (CAS No. 85–
68–7), Dibutyl phthalate (CAS No. 84–
74–2), and Dimethyl phthalate (CAS No.
131–11–3).
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§ 177.2600 Rubber Articles Intended
for Repeated Use
Diphenylguanidine phthalate (CAS
No. 17573–13–6), Amyl decyl phthalate
(CAS No. 7493–81–4), Dibutyl phthalate
(CAS No. 84–74–2), Didecyl phthalate
(CAS No. 84–77–5), Diisodecyl
phthalate (CAS No. 26761–40–0),
Dioctyl phthalate (CAS No. 117–84–0),
and Octyl decyl phthalate (CAS No.
119–07–3).
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§ 178.3740 Plasticizers in Polymeric
Substances
Butylbenzyl phthalate (CAS No. 85–
68–7), Dicyclohexyl phthalate (CAS No.
84–61–7), Diisononyl phthalate (CAS
No. 28553–12–0), Dihexyl phthalate
(CAS No. 84–75–3), and Diphenyl
phthalate (CAS No. 84–62–8).
§ 178.3910 Surface Lubricants Used in
the Manufacture of Metallic Articles
Diisodecyl phthalate (CAS No. 26761–
40–0), Di(2-ethylhexyl) phthalate (CAS
No. 117–81–7), and Diethyl phthalate
(CAS No. 84–66–2).
The petitioners request FDA to
consider that ortho-phthalates are a
class of chemically and
pharmacologically related substances,
and state that there is no longer a
reasonable certainty of no harm for the
food contact uses of the specified orthophthalates. If we determine that new
data are available that justify amending
the specified food additive regulations
in parts 175, 176, 177, and 178 so that
they will no longer provide for the use
of the ortho-phthalates, we will publish
such an amendment of these regulations
in the Federal Register, as set forth in
§ 171.130 and § 171.100 (21 CFR
171.100).
III. Amendment of 21 CFR 181.27
A portion of the submission relates to
uses of five ortho-phthalates that are
listed in § 181.27 as prior-sanctioned.
Those five ortho-phthalates are as
follows: Diethyl phthalate (CAS No. 84–
66–2), Ethyl phthalyl ethyl glycolate
(CAS No. 84–72–0), Butyl phthalyl butyl
glycolate (CAS No. 85–70–1), Diisooctyl
phthalate (CAS No. 27554–26–3), and
Di(2-ethylhexyl) phthalate (CAS No.
117–81–7). FDA has not filed as part of
the food additive petition the request to
revoke these prior sanctions. Section
201(s) of the FD&C Act exempts priorsanctioned materials from the definition
of a food additive (21 U.S.C. 321(s)).
Therefore, the request to revoke the
prior-sanction for these substances is
not within the scope of a food additive
petition under section 409(b) of the
FD&C Act (‘‘a petition proposing the
issuance of a regulation prescribing the
conditions under which such [food]
additive may be safety used’’). We have
informed petitioners that they may
submit a citizen petition under 21 CFR
10.30 requesting that FDA take this
action.
IV. New Regulation in 21 CFR Part 189
A portion of the submission requests
that FDA prohibit the food contact use
of the following eight ortho-phthalates:
Diisobutyl phthalate (CAS No. 84–69–
5), Di-n-butyl phthalate (CAS No. 84–
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31879
74–2), Butyl benzyl phthalate (CAS No.
85–68–7), Dicyclohexyl phthalate (CAS
No. 84–61–7), Di-n-hexyl phthalate
(CAS No. 84–75–3), Diisooctyl phthalate
(CAS No. 27554–26–3), Di(2-ethylhexyl)
phthalate (CAS No. 117–81–7), and
Diisononyl phthalate (CAS No. 28553–
12–0). The submission requests that
FDA take this action by issuing a new
regulation in part 189. FDA has not filed
as part of the food additive petition the
request to issue the proposed regulation
in part 189. Such a request is not within
the scope of a food additive petition
under section 409(b) of the FD&C Act
(‘‘a petition proposing the issuance of a
regulation prescribing the conditions
under which such [food] additive may
be safety used’’). We have informed
petitioners that they may submit a
citizen petition under 21 CFR 10.30
requesting that FDA take this action.
We also are reviewing the potential
environmental impact of the petitioners’
requested action. The petitioners have
claimed a categorical exclusion from
preparing an environmental assessment
or environmental impact statement
under 21 CFR 25.32(m). In accordance
with regulations promulgated under the
National Environmental Policy Act (40
CFR 1506.6(b)), we are placing the
environmental document submitted
with the subject petition on public
display at the Division of Dockets
Management (see ADDRESSES) so that
interested persons may review the
document. If we determine that the
petitioners’ claim of categorical
exclusion is warranted and that neither
an environmental assessment nor
environmental impact statement is
required, we will announce our
determination in the Federal Register if
this petition results in an amended
regulation(s). If we determine that the
claim of categorical exclusion is not
warranted we will place the
environmental assessment on public
display at the Division of Dockets
Management and provide notice in the
Federal Register announcing its
availability for review and comment.
Dated: May 13, 2016.
Dennis M. Keefe,
Director, Office of Food Additive Safety,
Center for Food Additive Safety and Applied
Nutrition.
[FR Doc. 2016–11866 Filed 5–19–16; 8:45 am]
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Agencies
[Federal Register Volume 81, Number 98 (Friday, May 20, 2016)]
[Proposed Rules]
[Pages 31877-31879]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2016-11866]
=======================================================================
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
Food and Drug Administration
21 CFR Parts 175, 176, 177, and 178
[Docket No. FDA-2016-F-1253]
Breast Cancer Fund, Center for Environmental Health, Center for
Food Safety, Center for Science in the Public Interest, Clean Water
Action, Consumer Federation of America, Earthjustice, Environmental
Defense Fund, Improving Kids' Environment, Learning Disabilities
Association of America, and Natural Resources Defense Council; Filing
of Food Additive Petition
AGENCY: Food and Drug Administration, HHS.
ACTION: Notice of petition.
-----------------------------------------------------------------------
SUMMARY: The Food and Drug Administration (FDA or we) is announcing
that we have filed a petition, submitted by Breast Cancer Fund, Center
for Environmental Health, Center for Food Safety, Center for Science in
the Public Interest, Clean Water Action, Consumer Federation of
America, Earthjustice, Environmental Defense Fund, Improving Kids'
Environment, Learning Disabilities Association of America, and Natural
Resources Defense Council proposing that we amend and/or revoke
specified regulations to no longer provide for the food contact use of
specified ortho-phthalates.
DATES: The food additive petition was filed on April 12, 2016. Submit
either electronic or written comments by July 19, 2016.
ADDRESSES: You may submit comments as follows:
Electronic Submissions
Submit electronic comments in the following way:
Federal eRulemaking Portal: https://www.regulations.gov.
Follow the instructions for submitting comments. Comments submitted
electronically, including attachments, to https://www.regulations.gov
will be posted to the docket unchanged. Because your comment will be
made public, you are solely responsible for ensuring that your comment
does not include any confidential information that you or a third party
may not wish to be posted, such as medical information, your or anyone
else's Social Security number, or confidential business information,
such as a manufacturing process. Please note that if you include your
name, contact
[[Page 31878]]
information, or other information that identifies you in the body of
your comments, that information will be posted on https://www.regulations.gov.
If you want to submit a comment with confidential
information that you do not wish to be made available to the public,
submit the comment as a written/paper submission and in the manner
detailed (see ``Written/Paper Submissions'' and ``Instructions'').
Written/Paper Submissions
Submit written/paper submissions as follows:
Mail/Hand delivery/Courier (for written/paper
submissions): Division of Dockets Management (HFA-305), Food and Drug
Administration, 5630 Fishers Lane, Rm. 1061, Rockville, MD 20852.
For written/paper comments submitted to the Division of
Dockets Management, FDA will post your comment, as well as any
attachments, except for information submitted, marked and identified,
as confidential, if submitted as detailed in ``Instructions.''
Instructions: All submissions received must include the Docket No.
FDA-2016-F-1253 for ``Breast Cancer Fund, Center for Environmental
Health, Center for Food Safety, Center for Science In The Public
Interest, Clean Water Action, Consumer Federation of America,
Earthjustice, Environmental Defense Fund, Improving Kids' Environment,
Learning Disabilities Association of America, and Natural Resources
Defense Council; Filing of Food Additive Petition.'' Received comments
will be placed in the docket and, except for those submitted as
``Confidential Submissions,'' publicly viewable at https://www.regulations.gov or at the Division of Dockets Management between 9
a.m. and 4 p.m., Monday through Friday.
Confidential Submissions--To submit a comment with
confidential information that you do not wish to be made publicly
available, submit your comments only as a written/paper submission. You
should submit two copies total. One copy will include the information
you claim to be confidential with a heading or cover note that states
``THIS DOCUMENT CONTAINS CONFIDENTIAL INFORMATION.'' The Agency will
review this copy, including the claimed confidential information, in
its consideration of comments. The second copy, which will have the
claimed confidential information redacted/blacked out, will be
available for public viewing and posted on https://www.regulations.gov.
Submit both copies to the Division of Dockets Management. If you do not
wish your name and contact information to be made publicly available,
you can provide this information on the cover sheet and not in the body
of your comments and you must identify this information as
``confidential.'' Any information marked as ``confidential'' will not
be disclosed except in accordance with 21 CFR 10.20 and other
applicable disclosure law. For more information about FDA's posting of
comments to public dockets, see 80 FR 56469, September 18, 2015, or
access the information at: https://www.fda.gov/regulatoryinformation/dockets/default.htm.
Docket: For access to the docket to read background documents or
the electronic and written/paper comments received, go to https://www.regulations.gov and insert the docket number, found in brackets in
the heading of this document, into the ``Search'' box and follow the
prompts and/or go to the Division of Dockets Management, 5630 Fishers
Lane, Rm. 1061, Rockville, MD 20852.
FOR FURTHER INFORMATION CONTACT: Kelly Randolph, Center for Food Safety
and Applied Nutrition (HFS-275), Food and Drug Administration, 5100
Paint Branch Pkwy., College Park, MD 20740-3835, 240-402-1188.
SUPPLEMENTARY INFORMATION:
I. Background
Under section 409(b)(5) of the Federal Food, Drug, and Cosmetic Act
(the FD&C Act) (21 U.S.C. 348(b)(5)), we are giving notice that we have
filed a food additive petition (FAP 6B4815), submitted by Breast Cancer
Fund, Center for Science in the Public Interest, Center for
Environmental Health, Center for Food Safety, Clean Water Action,
Consumer Federation of America, Earthjustice, Environmental Defense
Fund, Improving Kids' Environment, Learning Disabilities Association of
America, and Natural Resources Defense Council, c/o Mr. Thomas Neltner,
1875 Connecticut Ave. NW., Suite 600, Washington, DC 20009. The
submission proposes that we amend and/or revoke specified food additive
regulations under 21 CFR parts 175, 176, 177, and 178 to no longer
provide for the food contact use of specified ortho-phthalates. We have
filed this portion of the submission as a food additive petition. The
submission also requests that we amend our regulations in 21 CFR part
181 related to prior-sanctioned uses of specified ortho-phthalates and
issue a new regulation in 21 CFR part 189 prohibiting the use of eight
specific ortho-phthalates. We have declined to file these portions of
the submission as a food additive petition.
II. Amendment of 21 CFR Parts 175, 176, 177, and 178
In accordance with the procedures for amending or revoking a food
additive regulation in Sec. 171.130 (21 CFR 171.130), the petition
asks us to amend parts 175, 176, 177, and 178 to no longer provide for
the food contact use of certain specified ortho-phthalates. The
specified ortho-phthalates and corresponding regulations in parts 175,
176, 177, and 178 are as follows:
Sec. 175.105 Adhesives
Butyl benzyl phthalate (CAS No. 85-68-7), Butyldecyl phthalate (CAS
No. 89-19-0), Butyloctyl phthalate (CAS No. 84-78-6), Butyl phthalate
butyl glycolate (CAS No. 85-70-1), Di(butoxyethyl) phthalate (CAS
No.117-83-9), Dibutyl phthalate (CAS No. 84-74-2), Dicyclohexyl
phthalate (CAS No. 84-61-7), Di(2-ethylhexyl)hexahydrophthalate, Di(2-
ethylhexyl)phthalate (CAS No. 117-81-7), Diethyl phthalate (CAS No. 84-
66-2), Dihexyl phthalate (CAS No. 84-75-3), Dihydroabietylphthalate
(CAS No. 26760-71-4), Diisobutyl phthalate (CAS No. 84-69-5),
Diisodecyl phthalate (CAS No. 26761-40-0), Diisooctyl phthalate (CAS
No. 27554-26-3), Dimethyl phthalate (CAS No. 131-11-3), Dioctyl
phthalate (CAS No. 117-84-0), Diphenyl phthalate (CAS No. 84-62-8),
Ethyl phthalyl ethyl glycolate (CAS No. 84-72-0), Methyl phthalyl ethyl
glycolate (CAS No. 85-71-2), Octyldecyl phthalate (CAS No. 119-07-3),
and Diallyl phthalate (CAS No. 131-17-9).
Sec. 175.300 Resinous and Polymeric Coatings
Dibutyl phthalate (CAS No. 84-74-2), Diethyl phthalate (CAS No. 84-
66-2), Diisooctyl phthalate (CAS No. 27554-26-3), Di(2-ethylhexyl)
phthalate (CAS No. 117-81-7), and Diisodecyl phthalate (CAS No. 26761-
40-0).
Sec. 175.320 Resinous and Polymeric Coatings for Polyolefin Films
Butyl phthalyl butyl glycolate (CAS No. 85-70-1), Diethyl phthalate
(CAS No. 84-66-2), and Ethyl phthalyl ethyl glycolate (CAS No. 84-72-
0).
Sec. 176.170 Components of Paper and Paperboard in Contact With
Aqueous and Fatty Foods
Butylbenzyl phthalate (CAS No. 85-68-7), Dibutyl phthalate (CAS No.
84-74-2), Dicyclohexyl phthalate (CAS No. 84-61-7), and Diallyl
phthalate (CAS No. 131-17-9).
[[Page 31879]]
Sec. 176.180 Components of Paper and Paperboard in Contact With Dry
Food
Butyl benzyl phthalate (CAS No. 85-68-7) and Diallyl phthalate (CAS
No. 131-17-9).
Sec. 176.210 Defoaming Agents Used in the Manufacture of Paper and
Paperboard
Di(2-ethylhexyl) phthalate (CAS No. 117-81-7).
Sec. 176.300 Slimicides
Dibutyl phthalate (CAS No. 84-74-2), Didecyl phthalate (CAS No. 84-
77-5), and Dodecyl phthalate (CAS No. 21577-80-0).
Sec. 177.1010 Acrylic and Modified Acrylic Plastics, Semirigid and
Rigid
Di(2-ethylhexyl) phthalate (CAS No. 117-81-7) and Dimethyl
phthalate (CAS No. 131-11-3).
Sec. 177.1200 Cellophane
Castor oil phthalate with adipic acid and fumaric acid diethylene
glycol polyester (CAS No. 68650-73-7), Castor oil phthalate,
hydrogentated (FDA No. 977037-59-4), Dibutylphthalate (CAS No. 84-74-
2), Dicyclohexyl phthalate (CAS No. 84-61-7), Di(2-ethylhexy) phthalate
(CAS No. 117-81-7), Diisobutyl phthalate (CAS No. 84-69-5), and
Dimethylcyclohexyl phthalate (CAS No. 1322-94-7).
Sec. 177.1210 Closures With Sealing Gaskets for Food Containers
Diisodecyl phthalate (CAS No. 26761-40-0).
Sec. 177.1460 Melamine-Formaldehyde Resins in Molded Articles
Dioctyl phthalate (CAS No. 117-84-0).
Sec. 177.1590 Polyester Elastomers
Dimethyl orthophthalate (CAS No. 131-11-3).
Sec. 177.2420 Polyester Resins, Cross-Linked
Butyl benzyl phthalate (CAS No. 85-68-7), Dibutyl phthalate (CAS
No. 84-74-2), and Dimethyl phthalate (CAS No. 131-11-3).
Sec. 177.2600 Rubber Articles Intended for Repeated Use
Diphenylguanidine phthalate (CAS No. 17573-13-6), Amyl decyl
phthalate (CAS No. 7493-81-4), Dibutyl phthalate (CAS No. 84-74-2),
Didecyl phthalate (CAS No. 84-77-5), Diisodecyl phthalate (CAS No.
26761-40-0), Dioctyl phthalate (CAS No. 117-84-0), and Octyl decyl
phthalate (CAS No. 119-07-3).
Sec. 178.3740 Plasticizers in Polymeric Substances
Butylbenzyl phthalate (CAS No. 85-68-7), Dicyclohexyl phthalate
(CAS No. 84-61-7), Diisononyl phthalate (CAS No. 28553-12-0), Dihexyl
phthalate (CAS No. 84-75-3), and Diphenyl phthalate (CAS No. 84-62-8).
Sec. 178.3910 Surface Lubricants Used in the Manufacture of Metallic
Articles
Diisodecyl phthalate (CAS No. 26761-40-0), Di(2-ethylhexyl)
phthalate (CAS No. 117-81-7), and Diethyl phthalate (CAS No. 84-66-2).
The petitioners request FDA to consider that ortho-phthalates are a
class of chemically and pharmacologically related substances, and state
that there is no longer a reasonable certainty of no harm for the food
contact uses of the specified ortho-phthalates. If we determine that
new data are available that justify amending the specified food
additive regulations in parts 175, 176, 177, and 178 so that they will
no longer provide for the use of the ortho-phthalates, we will publish
such an amendment of these regulations in the Federal Register, as set
forth in Sec. 171.130 and Sec. 171.100 (21 CFR 171.100).
III. Amendment of 21 CFR 181.27
A portion of the submission relates to uses of five ortho-
phthalates that are listed in Sec. 181.27 as prior-sanctioned. Those
five ortho-phthalates are as follows: Diethyl phthalate (CAS No. 84-66-
2), Ethyl phthalyl ethyl glycolate (CAS No. 84-72-0), Butyl phthalyl
butyl glycolate (CAS No. 85-70-1), Diisooctyl phthalate (CAS No. 27554-
26-3), and Di(2-ethylhexyl) phthalate (CAS No. 117-81-7). FDA has not
filed as part of the food additive petition the request to revoke these
prior sanctions. Section 201(s) of the FD&C Act exempts prior-
sanctioned materials from the definition of a food additive (21 U.S.C.
321(s)). Therefore, the request to revoke the prior-sanction for these
substances is not within the scope of a food additive petition under
section 409(b) of the FD&C Act (``a petition proposing the issuance of
a regulation prescribing the conditions under which such [food]
additive may be safety used''). We have informed petitioners that they
may submit a citizen petition under 21 CFR 10.30 requesting that FDA
take this action.
IV. New Regulation in 21 CFR Part 189
A portion of the submission requests that FDA prohibit the food
contact use of the following eight ortho-phthalates: Diisobutyl
phthalate (CAS No. 84-69-5), Di-n-butyl phthalate (CAS No. 84-74-2),
Butyl benzyl phthalate (CAS No. 85-68-7), Dicyclohexyl phthalate (CAS
No. 84-61-7), Di-n-hexyl phthalate (CAS No. 84-75-3), Diisooctyl
phthalate (CAS No. 27554-26-3), Di(2-ethylhexyl) phthalate (CAS No.
117-81-7), and Diisononyl phthalate (CAS No. 28553-12-0). The
submission requests that FDA take this action by issuing a new
regulation in part 189. FDA has not filed as part of the food additive
petition the request to issue the proposed regulation in part 189. Such
a request is not within the scope of a food additive petition under
section 409(b) of the FD&C Act (``a petition proposing the issuance of
a regulation prescribing the conditions under which such [food]
additive may be safety used''). We have informed petitioners that they
may submit a citizen petition under 21 CFR 10.30 requesting that FDA
take this action.
We also are reviewing the potential environmental impact of the
petitioners' requested action. The petitioners have claimed a
categorical exclusion from preparing an environmental assessment or
environmental impact statement under 21 CFR 25.32(m). In accordance
with regulations promulgated under the National Environmental Policy
Act (40 CFR 1506.6(b)), we are placing the environmental document
submitted with the subject petition on public display at the Division
of Dockets Management (see ADDRESSES) so that interested persons may
review the document. If we determine that the petitioners' claim of
categorical exclusion is warranted and that neither an environmental
assessment nor environmental impact statement is required, we will
announce our determination in the Federal Register if this petition
results in an amended regulation(s). If we determine that the claim of
categorical exclusion is not warranted we will place the environmental
assessment on public display at the Division of Dockets Management and
provide notice in the Federal Register announcing its availability for
review and comment.
Dated: May 13, 2016.
Dennis M. Keefe,
Director, Office of Food Additive Safety, Center for Food Additive
Safety and Applied Nutrition.
[FR Doc. 2016-11866 Filed 5-19-16; 8:45 am]
BILLING CODE 4164-01-P