Labeling for Permanent Hysteroscopically-Placed Tubal Implants Intended for Sterilization, Draft Guidance for Industry and Food and Drug Administration Staff; Availability, 11577-11579 [2016-04790]
Download as PDF
11577
Federal Register / Vol. 81, No. 43 / Friday, March 4, 2016 / Notices
States’’). The evidence required by
MDUFMA is a copy of the most recent
Federal income tax return of the
applicant, and any affiliate, partner, or
parent firm. FDA will review these
materials and decide whether an
applicant is a small business within the
meaning of MDUFMA.
The 2007 Amendments provide an
alternative way for a foreign business to
qualify as a small business eligible to
pay a significantly lower fee when a
medical device user fee must be paid
(Form FDA 3602A, ‘‘FY 2016 MDUFMA
Foreign Small Business Qualification
Certification—For a Business
Headquartered Outside the United
States’’). Before passage of the 2007
Amendments, the only way a business
could qualify as a small business was to
submit a Federal (U.S.) income tax
return showing its gross receipts or sales
that did not exceed a statutory
threshold, currently, $100 million. If a
business could not provide a Federal
income tax return, it did not qualify as
a small business and had to pay the
standard (full) fee. Because many
foreign businesses have not, and cannot,
file a Federal (U.S.) income tax return,
this requirement has effectively
prevented those businesses from
qualifying for the small business fee
rates. Thus, foreign governments,
including the European Union, have
objected. In lieu of a Federal income tax
return, the 2007 Amendments will
allow a foreign business to qualify as a
small business by submitting a
certification from its national taxing
authority, the foreign equivalent of our
Internal Revenue Service. This
certification, referred to as a ‘‘National
Taxing Authority Certification,’’ must:
(1) Be in English; (2) be from the
national taxing authority of the country
in which the business is headquartered;
(3) provide the business’ gross receipts
or sales for the most recent year, in both
the local currency and in U.S. dollars,
and the exchange rate used in
converting local currency to U.S.
dollars; (4) provide the dates during
which the reported receipts or sales
were collected; and (5) bear the official
seal of the national taxing authority.
Both Forms FDA 3602 and FDA
3602A are available in the guidance
document, ‘‘FY 2016 Medical Device
User Fee Small Business Qualification
and Certification; Guidance for Industry,
Food and Drug Administration Staff,
and Foreign Governments’’ available on
the Internet at: https://www.fda.gov/ucm/
groups/fdagov-public/@fdagov-meddevgen/documents/document/
ucm456779.pdf. This guidance
describes the criteria FDA will use to
decide whether an entity qualifies as a
MDUFMA small business and will help
prospective applicants understand what
they need to do to meet the small
business criteria for FY 2016.
The estimated burden is based on the
number of applications received in the
last 3 years and includes time required
to collect the required information.
Based on our experience with Form
FDA 3602, FDA believes it will take
each respondent 1 hour to complete the
form. Based on our experience with
Form FDA 3602A, FDA also believes
that it will take each respondent 1 hour
to complete.
In the Federal Register of September
17, 2015 (80 FR 55854), FDA published
a 60-day notice requesting public
comment on the proposed collection of
information. Although one comment
was received, it was not responsive to
the four collection of information topics
solicited and therefore will not be
discussed in this document.
FDA estimates the burden of this
collection of information as follows:
TABLE 1—ESTIMATED ANNUAL REPORTING BURDEN 1
Number of
respondents
FDA Form No.
FDA 3602—FY 2016 MDUFA Small Business Qualification
and Certification For a Business Headquartered in the
United States ....................................................................
FDA 3602A—FY 2016 MDUFA Foreign Small Business
Qualification and Certification For a Business
Headquartered Outside the United States .......................
Total hours
1
3,600
1
3,600
1,400
1
1,400
1
1,400
........................
........................
........................
........................
5,000
are no capital costs or operating and maintenance costs associated with this collection of information.
Dated: February 29, 2016.
Leslie Kux,
Associate Commissioner for Policy.
[FR Doc. 2016–04704 Filed 3–3–16; 8:45 am]
BILLING CODE 4164–01–P
jstallworth on DSK7TPTVN1PROD with NOTICES
Average
burden per
response
Total annual
responses
3,600
Total ..............................................................................
1 There
Number of
responses per
respondent
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA–2016–D–0435]
Labeling for Permanent
Hysteroscopically-Placed Tubal
Implants Intended for Sterilization,
Draft Guidance for Industry and Food
and Drug Administration Staff;
Availability
AGENCY:
Food and Drug Administration,
HHS.
ACTION:
Notice of availability.
The Food and Drug
Administration (FDA or Agency) is
announcing the availability of the draft
SUMMARY:
VerDate Sep<11>2014
15:22 Mar 03, 2016
Jkt 238001
PO 00000
Frm 00070
Fmt 4703
Sfmt 4703
guidance entitled ‘‘Labeling for
Permanent Hysteroscopically-Placed
Tubal Implants Intended for
Sterilization.’’ This draft guidance
addresses the inclusion of a boxed
warning and a patient decision checklist
in the product labeling for permanent
hysteroscopically-placed tubal implants
intended for female sterilization and as
well as the content and format of those
materials. This draft guidance is being
issued in response to information
provided to FDA, including in
comments made at a 2015 Panel meeting
and in comments submitted to the
associated public docket, that women
are not receiving or understanding
information relating to the risks and
benefits of this type of device. This draft
E:\FR\FM\04MRN1.SGM
04MRN1
11578
Federal Register / Vol. 81, No. 43 / Friday, March 4, 2016 / Notices
guidance is not final nor is it in effect
at this time.
DATES: Although you can comment on
any guidance at any time (see 21 CFR
10.115(g)(5)), to ensure that the Agency
considers your comment of this draft
guidance before it begins work on the
final version of the guidance, submit
either electronic or written comments
on the draft guidance by May 3, 2016.
ADDRESSES: You may submit comments
as follows:
Electronic Submissions
Submit electronic comments in the
following way:
• Federal eRulemaking Portal: https://
www.regulations.gov. Follow the
instructions for submitting comments.
Comments submitted electronically,
including attachments, to https://
www.regulations.gov will be posted to
the docket unchanged. Because your
comment will be made public, you are
solely responsible for ensuring that your
comment does not include any
confidential information that you or a
third party may not wish to be posted,
such as medical information, your or
anyone else’s Social Security number, or
confidential business information, such
as a manufacturing process. Please note
that if you include your name, contact
information, or other information that
identifies you in the body of your
comments, that information will be
posted on https://www.regulations.gov.
• If you want to submit a comment
with confidential information that you
do not wish to be made available to the
public, submit the comment as a
written/paper submission and in the
manner detailed (see ‘‘Written/Paper
Submissions’’ and ‘‘Instructions’’).
jstallworth on DSK7TPTVN1PROD with NOTICES
Written/Paper Submissions
Submit written/paper submissions as
follows:
• Mail/Hand delivery/Courier (for
written/paper submissions): Division of
Dockets Management (HFA–305), Food
and Drug Administration, 5630 Fishers
Lane, Rm. 1061, Rockville, MD 20852.
• For written/paper comments
submitted to the Division of Dockets
Management, FDA will post your
comment, as well as any attachments,
except for information submitted,
marked and identified, as confidential,
if submitted as detailed in
‘‘Instructions.’’
Instructions: All submissions received
must include the Docket No. FDA–
2016–D–0435 for ‘‘Labeling for
Permanent Hysteroscopically-Placed
Tubal Implants Intended for
Sterilization.’’ Received comments will
be placed in the docket and, except for
VerDate Sep<11>2014
15:22 Mar 03, 2016
Jkt 238001
those submitted as ‘‘Confidential
Submissions,’’ publicly viewable at
https://www.regulations.gov or at the
Division of Dockets Management
between 9 a.m. and 4 p.m., Monday
through Friday.
• Confidential Submissions—To
submit a comment with confidential
information that you do not wish to be
made publicly available, submit your
comments only as a written/paper
submission. You should submit two
copies total. One copy will include the
information you claim to be confidential
with a heading or cover note that states
‘‘THIS DOCUMENT CONTAINS
CONFIDENTIAL INFORMATION.’’ The
Agency will review this copy, including
the claimed confidential information, in
its consideration of comments. The
second copy, which will have the
claimed confidential information
redacted/blacked out, will be available
for public viewing and posted on https://
www.regulations.gov. Submit both
copies to the Division of Dockets
Management. If you do not wish your
name and contact information to be
made publicly available, you can
provide this information on the cover
sheet and not in the body of your
comments and you must identify this
information as ‘‘confidential.’’ Any
information marked as ‘‘confidential’’
will not be disclosed except in
accordance with 21 CFR 10.20 and other
applicable disclosure law. For more
information about FDA’s posting of
comments to public dockets, see 80 FR
56469, September 18, 2015, or access
the information at: https://www.fda.gov/
regulatoryinformation/dockets/
default.htm.
Docket: For access to the docket to
read background documents or the
electronic and written/paper comments
received, go to https://
www.regulations.gov and insert the
docket number, found in brackets in the
heading of this document, into the
‘‘Search’’ box and follow the prompts
and/or go to the Division of Dockets
Management, 5630 Fishers Lane, Rm.
1061, Rockville, MD 20852.
Submit written requests for a single
copies of the guidance to the Office of
the Center Director, Guidance and
Policy Development, Center for Devices
and Radiological Health, Food and Drug
Administration, 10903 New Hampshire
Ave., Bldg. 66, Rm. 5431, Silver Spring,
MD 20993–0002. Send one selfaddressed adhesive label to assist that
office in processing your request. See
SUPPLEMENTARY INFORMATION section for
electronic access to the draft guidance
document.
PO 00000
Frm 00071
Fmt 4703
Sfmt 4703
FOR FURTHER INFORMATION CONTACT:
Jason Roberts, Division of Reproductive,
Gastro-Renal, and Urological Devices,
Center for Devices and Radiological
Health, Food and Drug Administration,
10903 New Hampshire Ave., Bldg. 66,
Rm. G218, Silver Spring, MD 20993–
0002, 240–402–6400.
SUPPLEMENTARY INFORMATION:
I. Background
Female sterilization is a commonly
performed surgical procedure that
permanently prevents a woman from
becoming pregnant by occluding her
fallopian tubes. Traditionally, surgery
has been performed by bilateral tubal
ligation (BTL) through a laparotomy, a
mini-laparotomy, transvaginal approach
or at the time of cesarean delivery, and,
more recently, laparoscopy. During BTL,
the fallopian tubes are cut or physically
occluded by using various procedures or
medical instruments, such as
electrosurgical coagulation, implantable
clips, or rings. On November 4, 2002,
FDA approved the Essure System for
Permanent Birth Control, the first
permanent hysteroscopically-placed
tubal implant, as an alternative, nonincisional method of providing female
sterilization. As the number of
hysteroscopic sterilizations with such
devices has increased, additional
information, including reports of
adverse events, has accumulated. Some
of these events have resulted in surgery
and/or removal of the implants.
The Federal Register on July 22, 2015
(80 FR 43440), announced a meeting of
a public advisory committee of the FDA
to seek expert scientific and clinical
opinion on the risks and benefits of the
Essure System for Permanent Birth
Control. On September 24, 2015, FDA
convened its Obstetrics and Gynecology
Devices Panel of the Medical Devices
Advisory Committee to discuss
available data regarding benefits, risks,
and potential mitigation strategies to
prevent or reduce the frequency/severity
of the adverse events reported in
association with this device (Ref. 1).
FDA is issuing this draft guidance
document after considering the input of
the Panel members and other
stakeholders. FDA believes that the
labeling described in this guidance will
help to ensure that women are receiving
and understanding information about
the risks and benefits of these devices so
that they can make informed decisions
regarding use of these devices. In
addition to issuing this guidance, FDA
continues to determine what, if any,
further actions are warranted in
response to these reported adverse
events.
E:\FR\FM\04MRN1.SGM
04MRN1
Federal Register / Vol. 81, No. 43 / Friday, March 4, 2016 / Notices
www.fda.gov/AdvisoryCommittees/
CommitteesMeetingMaterials/
MedicalDevices/MedicalDevices
AdvisoryCommittee/Obstetricsand
GynecologyDevices/
ucm463457.htm.
II. Significance of Guidance
This draft guidance is being issued
consistent with FDA’s good guidance
practices regulation (21 CFR 10.115).
The draft guidance, when finalized, will
represent the current thinking of FDA
on ‘‘Labeling for Permanent
Hysteroscopically-Placed Tubal
Implants Intended for Sterilization.’’ It
does not establish any rights for any
person and is not binding on FDA or the
public. You can use an alternative
approach if it satisfies the requirements
of the applicable statutes and
regulations.
III. Electronic Access
Persons interested in obtaining a copy
of the draft guidance may do so by
downloading an electronic copy from
the Internet. A search capability for all
Center for Devices and Radiological
Health guidance documents is available
at https://www.fda.gov/MedicalDevices/
DeviceRegulationandGuidance/
GuidanceDocuments/default.htm.
Guidance documents are also available
at https://www.regulations.gov. Persons
unable to download an electronic copy
of ‘‘Labeling for Permanent
Hysteroscopically-Placed Tubal
Implants Intended for Sterilization’’
may send an email request to CDRHGuidance@fda.hhs.gov to receive an
electronic copy of the document. Please
use the document number 1500051 to
identify the guidance you are
requesting.
IV. Paperwork Reduction Act of 1995
This draft guidance refers to
previously approved collections of
information found in FDA regulations.
These collections of information are
subject to review by the Office of
Management and Budget (OMB) under
the Paperwork Reduction Act of 1995
(44 U.S.C. 3501–3520). The collections
of information in 21 CFR part 801,
regarding labeling have been approved
under OMB control number 0910–0485.
jstallworth on DSK7TPTVN1PROD with NOTICES
V. Reference
The following reference is on display
in the Division of Dockets Management
(see ADDRESSES) and is available for
viewing by interested persons between
9 a.m. and 4 p.m., Monday through
Friday; it are also available
electronically at https://
www.regulations.gov. FDA has verified
the Web site address, as of the date this
document publishes in the Federal
Register, but Web sites are subject to
change over time.
1. Meeting Materials of the Obstetrics
and Gynecology Devices Panel
(2015), available at https://
VerDate Sep<11>2014
15:22 Mar 03, 2016
Jkt 238001
Dated: February 29, 2016.
Leslie Kux,
Associate Commissioner for Policy.
[FR Doc. 2016–04790 Filed 3–3–16; 8:45 am]
BILLING CODE 4164–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Substance Abuse and Mental Health
Services Administration
Announcement of Requirements and
Registration for the Opioid Overdose
Prevention Challenge
SAMHSA, HHS.
Notice.
AGENCY:
In summarizing the challenge
that will be issued by your agency,
please answer the following four
questions:
(1) What action is being taken?
The Substance Abuse and Mental
Health Services Administration
(SAMHSA) has issued a challenge to
developers to help support patients in
recovery who are receiving medication
assisted treatment for opioid use
disorder with an innovative app that
provides features and information that
support their recovery.
(2) Why is this action necessary?
Addressing the opioid epidemic is a
top priority for the U.S. Department of
Health and Human Services and the
Secretary is committed to evidenceinformed interventions to turn the tide
against opioid drug-related overdose
and misuse. To that end, Substance
Abuse and Mental Health Services
Administration (SAMHSA) is issuing a
three-month challenge to spur
developers to create an app that
provides additional recovery support to
patients receiving outpatient
medication-assisted treatment for opioid
use disorder.
(3) What is the objective of the
challenge?
To provide support to people in
recovery from opioid use disorder
receiving medication assisted-treatment
so that they can maintain treatment and
achieve long-term recovery.
(4) What is the intended effect of this
action?
An increase in the number of
individuals with opioid use disorders
SUMMARY:
PO 00000
Frm 00072
Fmt 4703
Sfmt 4703
maintaining recovery; and a reduction
in the number of deaths from opioid
overdose.
The challenge starts on March 4,
2016 10:00 a.m. ET. The challenge ends
on May 27, 2016 11:59 p.m. ET.
FOR FURTHER INFORMATION CONTACT:
Danielle Tarino Rivkin, Health
Information Technology Team, Center
for Substance Abuse Treatment,
Substance Abuse and Mental Health
Services Administration, U.S.
Department of Health and Human
Services, Public Health Advisor,
SAMHSA/CSAT, 5600 Fishers Lane,
Rockville, MD 20857, Phone:
240.276.2857, Email: Danielle.Tarino@
samhsa.hhs.gov.
DATES:
SUPPLEMENTARY INFORMATION:
Subject of Challenge Competition:
Opioid Recovery Support.
Eligibility Rules for Participating in the
Competition
Authority: 15 U.S.C. 3719.
ACTION:
11579
To satisfy the mandatory provisions of
the COMPETES Act, use the following
language:
A. The Competition is open only to:
(i) Individuals who are at least 18
years of age at the time of entry, and are
citizens or permanent residents of the
United States as of the time of entry;
(ii) teams of eligible individuals
where each team member meets the
eligibility requirements for individual
Contestants; and
(iii) corporations (including not-forprofit corporations and other nonprofit
organizations), limited liability
companies, partnerships, and other legal
entities that, at the time of entry, are
domiciled (or incorporated) in the
United States, have been duly organized
or incorporated and validly exist, and
employ no more than one hundred (100)
people (‘‘Organizations’’).
B. Each team or Organization shall
appoint one individual (the
‘‘Representative’’) to represent and act,
including entering a Submission, on
behalf of said team or Organization. The
Representative must meet the eligibility
requirements for an individual
Contestant and must be duly authorized
to submit on behalf of the team or
Organization. The Representative
represents and warrants that: (i) He/she
is duly authorized to act on behalf of the
team or Organization; and (ii) each
member of the team (or in the case of
Organization, each participating
member) has read the Official Rules and
agrees to abide by these Official Rules.
The Representative will ensure that
each member of the team or
Organization reads, agrees to, and
complies with the Official Rules.
E:\FR\FM\04MRN1.SGM
04MRN1
Agencies
[Federal Register Volume 81, Number 43 (Friday, March 4, 2016)]
[Notices]
[Pages 11577-11579]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2016-04790]
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA-2016-D-0435]
Labeling for Permanent Hysteroscopically-Placed Tubal Implants
Intended for Sterilization, Draft Guidance for Industry and Food and
Drug Administration Staff; Availability
AGENCY: Food and Drug Administration, HHS.
ACTION: Notice of availability.
-----------------------------------------------------------------------
SUMMARY: The Food and Drug Administration (FDA or Agency) is announcing
the availability of the draft guidance entitled ``Labeling for
Permanent Hysteroscopically-Placed Tubal Implants Intended for
Sterilization.'' This draft guidance addresses the inclusion of a boxed
warning and a patient decision checklist in the product labeling for
permanent hysteroscopically-placed tubal implants intended for female
sterilization and as well as the content and format of those materials.
This draft guidance is being issued in response to information provided
to FDA, including in comments made at a 2015 Panel meeting and in
comments submitted to the associated public docket, that women are not
receiving or understanding information relating to the risks and
benefits of this type of device. This draft
[[Page 11578]]
guidance is not final nor is it in effect at this time.
DATES: Although you can comment on any guidance at any time (see 21 CFR
10.115(g)(5)), to ensure that the Agency considers your comment of this
draft guidance before it begins work on the final version of the
guidance, submit either electronic or written comments on the draft
guidance by May 3, 2016.
ADDRESSES: You may submit comments as follows:
Electronic Submissions
Submit electronic comments in the following way:
Federal eRulemaking Portal: https://www.regulations.gov.
Follow the instructions for submitting comments. Comments submitted
electronically, including attachments, to https://www.regulations.gov
will be posted to the docket unchanged. Because your comment will be
made public, you are solely responsible for ensuring that your comment
does not include any confidential information that you or a third party
may not wish to be posted, such as medical information, your or anyone
else's Social Security number, or confidential business information,
such as a manufacturing process. Please note that if you include your
name, contact information, or other information that identifies you in
the body of your comments, that information will be posted on https://www.regulations.gov.
If you want to submit a comment with confidential
information that you do not wish to be made available to the public,
submit the comment as a written/paper submission and in the manner
detailed (see ``Written/Paper Submissions'' and ``Instructions'').
Written/Paper Submissions
Submit written/paper submissions as follows:
Mail/Hand delivery/Courier (for written/paper
submissions): Division of Dockets Management (HFA-305), Food and Drug
Administration, 5630 Fishers Lane, Rm. 1061, Rockville, MD 20852.
For written/paper comments submitted to the Division of
Dockets Management, FDA will post your comment, as well as any
attachments, except for information submitted, marked and identified,
as confidential, if submitted as detailed in ``Instructions.''
Instructions: All submissions received must include the Docket No.
FDA-2016-D-0435 for ``Labeling for Permanent Hysteroscopically-Placed
Tubal Implants Intended for Sterilization.'' Received comments will be
placed in the docket and, except for those submitted as ``Confidential
Submissions,'' publicly viewable at https://www.regulations.gov or at
the Division of Dockets Management between 9 a.m. and 4 p.m., Monday
through Friday.
Confidential Submissions--To submit a comment with
confidential information that you do not wish to be made publicly
available, submit your comments only as a written/paper submission. You
should submit two copies total. One copy will include the information
you claim to be confidential with a heading or cover note that states
``THIS DOCUMENT CONTAINS CONFIDENTIAL INFORMATION.'' The Agency will
review this copy, including the claimed confidential information, in
its consideration of comments. The second copy, which will have the
claimed confidential information redacted/blacked out, will be
available for public viewing and posted on https://www.regulations.gov.
Submit both copies to the Division of Dockets Management. If you do not
wish your name and contact information to be made publicly available,
you can provide this information on the cover sheet and not in the body
of your comments and you must identify this information as
``confidential.'' Any information marked as ``confidential'' will not
be disclosed except in accordance with 21 CFR 10.20 and other
applicable disclosure law. For more information about FDA's posting of
comments to public dockets, see 80 FR 56469, September 18, 2015, or
access the information at: https://www.fda.gov/regulatoryinformation/dockets/default.htm.
Docket: For access to the docket to read background documents or
the electronic and written/paper comments received, go to https://www.regulations.gov and insert the docket number, found in brackets in
the heading of this document, into the ``Search'' box and follow the
prompts and/or go to the Division of Dockets Management, 5630 Fishers
Lane, Rm. 1061, Rockville, MD 20852.
Submit written requests for a single copies of the guidance to the
Office of the Center Director, Guidance and Policy Development, Center
for Devices and Radiological Health, Food and Drug Administration,
10903 New Hampshire Ave., Bldg. 66, Rm. 5431, Silver Spring, MD 20993-
0002. Send one self-addressed adhesive label to assist that office in
processing your request. See SUPPLEMENTARY INFORMATION section for
electronic access to the draft guidance document.
FOR FURTHER INFORMATION CONTACT: Jason Roberts, Division of
Reproductive, Gastro-Renal, and Urological Devices, Center for Devices
and Radiological Health, Food and Drug Administration, 10903 New
Hampshire Ave., Bldg. 66, Rm. G218, Silver Spring, MD 20993-0002, 240-
402-6400.
SUPPLEMENTARY INFORMATION:
I. Background
Female sterilization is a commonly performed surgical procedure
that permanently prevents a woman from becoming pregnant by occluding
her fallopian tubes. Traditionally, surgery has been performed by
bilateral tubal ligation (BTL) through a laparotomy, a mini-laparotomy,
transvaginal approach or at the time of cesarean delivery, and, more
recently, laparoscopy. During BTL, the fallopian tubes are cut or
physically occluded by using various procedures or medical instruments,
such as electrosurgical coagulation, implantable clips, or rings. On
November 4, 2002, FDA approved the Essure System for Permanent Birth
Control, the first permanent hysteroscopically-placed tubal implant, as
an alternative, non-incisional method of providing female
sterilization. As the number of hysteroscopic sterilizations with such
devices has increased, additional information, including reports of
adverse events, has accumulated. Some of these events have resulted in
surgery and/or removal of the implants.
The Federal Register on July 22, 2015 (80 FR 43440), announced a
meeting of a public advisory committee of the FDA to seek expert
scientific and clinical opinion on the risks and benefits of the Essure
System for Permanent Birth Control. On September 24, 2015, FDA convened
its Obstetrics and Gynecology Devices Panel of the Medical Devices
Advisory Committee to discuss available data regarding benefits, risks,
and potential mitigation strategies to prevent or reduce the frequency/
severity of the adverse events reported in association with this device
(Ref. 1). FDA is issuing this draft guidance document after considering
the input of the Panel members and other stakeholders. FDA believes
that the labeling described in this guidance will help to ensure that
women are receiving and understanding information about the risks and
benefits of these devices so that they can make informed decisions
regarding use of these devices. In addition to issuing this guidance,
FDA continues to determine what, if any, further actions are warranted
in response to these reported adverse events.
[[Page 11579]]
II. Significance of Guidance
This draft guidance is being issued consistent with FDA's good
guidance practices regulation (21 CFR 10.115). The draft guidance, when
finalized, will represent the current thinking of FDA on ``Labeling for
Permanent Hysteroscopically-Placed Tubal Implants Intended for
Sterilization.'' It does not establish any rights for any person and is
not binding on FDA or the public. You can use an alternative approach
if it satisfies the requirements of the applicable statutes and
regulations.
III. Electronic Access
Persons interested in obtaining a copy of the draft guidance may do
so by downloading an electronic copy from the Internet. A search
capability for all Center for Devices and Radiological Health guidance
documents is available at https://www.fda.gov/MedicalDevices/DeviceRegulationandGuidance/GuidanceDocuments/default.htm. Guidance
documents are also available at https://www.regulations.gov. Persons
unable to download an electronic copy of ``Labeling for Permanent
Hysteroscopically-Placed Tubal Implants Intended for Sterilization''
may send an email request to CDRH-Guidance@fda.hhs.gov to receive an
electronic copy of the document. Please use the document number 1500051
to identify the guidance you are requesting.
IV. Paperwork Reduction Act of 1995
This draft guidance refers to previously approved collections of
information found in FDA regulations. These collections of information
are subject to review by the Office of Management and Budget (OMB)
under the Paperwork Reduction Act of 1995 (44 U.S.C. 3501-3520). The
collections of information in 21 CFR part 801, regarding labeling have
been approved under OMB control number 0910-0485.
V. Reference
The following reference is on display in the Division of Dockets
Management (see ADDRESSES) and is available for viewing by interested
persons between 9 a.m. and 4 p.m., Monday through Friday; it are also
available electronically at https://www.regulations.gov. FDA has
verified the Web site address, as of the date this document publishes
in the Federal Register, but Web sites are subject to change over time.
1. Meeting Materials of the Obstetrics and Gynecology Devices Panel
(2015), available at https://www.fda.gov/AdvisoryCommittees/CommitteesMeetingMaterials/MedicalDevices/MedicalDevicesAdvisoryCommittee/ObstetricsandGynecologyDevices/ucm463457.htm.
Dated: February 29, 2016.
Leslie Kux,
Associate Commissioner for Policy.
[FR Doc. 2016-04790 Filed 3-3-16; 8:45 am]
BILLING CODE 4164-01-P