Designation of a Class of Employees for Addition to the Special Exposure Cohort, 10633-10634 [2016-04415]
Download as PDF
Federal Register / Vol. 81, No. 40 / Tuesday, March 1, 2016 / Notices
received, go to https://
www.regulations.gov and insert the
docket number, found in brackets in the
heading of this document, into the
‘‘Search’’ box and follow the prompts,
and/or go to the Division of Dockets
Management, 5630 Fishers Lane, Rm.
1061, Rockville, MD 20852.
Submit written requests for single
copies of the draft guidance to the Office
of Communication, Outreach and
Development, Center for Biologics
Evaluation and Research (CBER), Food
and Drug Administration, 10903 New
Hampshire Ave., Bldg. 71, Rm. 3128,
Silver Spring, MD 20993–0002. Send
one self-addressed adhesive label to
assist the office in processing your
requests. The draft guidance may also be
obtained by mail by calling CBER at 1–
800–835–4709 or 240–402–8010. See
the SUPPLEMENTARY INFORMATION section
for electronic access to the draft
guidance document.
FOR FURTHER INFORMATION CONTACT:
Gretchen Opper, Center for Biologics
Evaluation and Research, Food and
Drug Administration, 10903 New
Hampshire Ave., Bldg. 71, Rm. 7301,
Silver Spring, MD 20993–0002, 240–
402–7911.
SUPPLEMENTARY INFORMATION:
asabaliauskas on DSK5VPTVN1PROD with NOTICES
I. Background
FDA is announcing the availability of
a draft document entitled ‘‘Enforcement
Policy Regarding Investigational New
Drug Requirements for Use of Fecal
Microbiota for Transplantation to Treat
Clostridium difficile Infection Not
Responsive to Standard Therapies.’’ The
draft guidance document provides
members of the medical and scientific
community and other interested persons
with notice that, when finalized, we
intend to exercise enforcement
discretion under limited conditions,
regarding the IND requirements for the
use of FMT to treat C. difficile infection
not responding to standard therapies.
FDA intends to exercise this discretion,
provided that: (1) The licensed health
care provider treating the patient
obtains adequate consent from the
patient or his or her legally authorized
representative for the use of FMT
products. The consent should include,
at a minimum, a statement that the use
of FMT products to treat C. difficile is
investigational and a discussion of its
reasonably foreseeable risks; (2) the
FMT product is not obtained from a
stool bank; and (3) the stool donor and
stool are qualified by screening and
testing performed under the direction of
the licensed health care provider for the
purpose of providing the FMT product
for treatment of the patient.
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20:18 Feb 29, 2016
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FDA has developed this policy to
assure that patients with C. difficile
infection not responding to standard
therapies may have access to this
treatment, while addressing and
controlling the risks that centralized
manufacturing in stool banks presents to
subjects. FDA intends for this to be an
interim policy, while the Agency
develops a comprehensive approach for
the study and use of FMT products
under IND.
A stool bank is defined, for the
purpose of this guidance, as an
establishment that collects, prepares,
and stores FMT product for distribution
to other establishments, health care
providers, or other entities for use in
patient therapy or clinical research. An
establishment that collects or prepares
FMT products solely under the
direction of licensed health care
providers for the purpose of treating
their patients (e.g., a hospital laboratory)
is not considered to be a stool bank
under this guidance.
In the draft guidance, FDA provides
that the stool bank sponsor may request
a waiver of certain IND regulations
relating to the obligations of
investigators and subinvestigators (e.g.,
certain sections of the Statement of
Investigator Form FDA 1572 that may
not be applicable to FMT provided to
the health care provider to treat their
patients) (21 CFR 312.10). FDA is
requesting comments on which IND
regulations are appropriate to waive. In
particular, FDA is requesting comments
on the requirement for institutional
review board review of the use of FMT
to treat patients with C. difficile
infection not responding to standard
therapies when the FMT is provided by
a stool bank (21 CFR 312.23(a)(1)(iv)
and 21 CFR 312.66).
In the draft guidance, FDA proposes
a revised policy with regard to patient
access to FMT. The provision that the
donor be known either to the patient or
to the treating licensed health care
provider, a concept that was used in the
March 2014 draft guidance, was subject
to difficulties in interpretation, and the
revised approach more accurately
reflects our intent to mitigate risk, based
on the number of patients exposed to a
particular donor or manufacturing
practice rather than the risk inherent
from any one donor. Although FDA
acknowledges that directed donations
present different risks than stool bank
donations, the number of persons
exposed through a directed donation
will be limited. FDA also requests
comments on this revised policy. The
draft guidance replaces the draft
guidance of the same title, dated March
2014 and, when finalized, is intended to
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10633
supersede the document of the same
title, dated July 2013.
The draft guidance is being issued
consistent with FDA’s good guidance
practices regulation (21 CFR 10.115).
The draft guidance, when finalized, will
represent the current thinking of FDA
on ‘‘Enforcement Policy Regarding
Investigational New Drug Requirements
for Use of Fecal Microbiota for
Transplantation to Treat Clostridium
difficile Infection Not Responsive to
Standard Therapies.’’ It does not
establish any rights for any person and
is not binding on FDA or the public.
You can use an alternative approach if
it satisfies the requirements of the
applicable statutes and regulations.
II. Paperwork Reduction Act of 1995
The draft guidance refers to
previously approved collections of
information found in FDA regulations.
These collections of information are
subject to review by the Office of
Management and Budget (OMB) under
the Paperwork Reduction Act of 1995
(44 U.S.C. 3501–3520). The collections
of information in 21 CFR part 312 have
been approved under OMB control
number 0910–0014. The collections of
information in 21 CFR part 50 have been
approved under OMB control number
0910–0755.
III. Electronic Access
Persons with access to the Internet
may obtain the draft guidance at either
https://www.fda.gov/
BiologicsBloodVaccines/
GuidanceCompliance
RegulatoryInformation/Guidances/
default.htm or https://
www.regulations.gov.
Dated: February 23, 2016.
Leslie Kux,
Associate Commissioner for Policy.
[FR Doc. 2016–04372 Filed 2–29–16; 8:45 am]
BILLING CODE 4164–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Designation of a Class of Employees
for Addition to the Special Exposure
Cohort
National Institute for
Occupational Safety and Health
(NIOSH), Centers for Disease Control
and Prevention, Department of Health
and Human Services (HHS).
ACTION: Notice.
AGENCY:
HHS gives notice of a
decision to designate a class of
employees from the Battelle
Laboratories—King Avenue site in
SUMMARY:
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01MRN1
10634
Federal Register / Vol. 81, No. 40 / Tuesday, March 1, 2016 / Notices
Columbus, Ohio, as an addition to the
Special Exposure Cohort (SEC) under
the Energy Employees Occupational
Illness Compensation Program Act of
2000.
FOR FURTHER INFORMATION CONTACT:
Stuart L. Hinnefeld, Director, Division
of Compensation Analysis and Support,
NIOSH, 1090 Tusculum Avenue, MS C–
46, Cincinnati, OH 45226–1938,
Telephone 1–877–222–7570.
Information requests can also be
submitted by email to DCAS@CDC.GOV.
SUPPLEMENTARY INFORMATION: On
February 18, 2016, as provided for
under 42 U.S.C. 7384l(14)(C),the
Secretary of HHS designated the
following class of employees as an
addition to the SEC:
All Atomic Weapons Employees who
worked at the facility owned by the Battelle
Laboratories at the King Avenue site in
Columbus, Ohio, during the period from July
1, 1956, through December 31, 1970, for a
number of work days aggregating at least 250
work days, occurring either solely under this
employment, or in combination with work
days within the parameters established for
one or more other classes of employees
included in the Special Exposure Cohort.
This designation will become
effective on March 19, 2016, unless
Congress provides otherwise prior to the
effective date. After this effective date,
HHS will publish a notice in the
Federal Register reporting the addition
of this class to the SEC or the result of
any provision by Congress regarding the
decision by HHS to add the class to the
SEC.
Authority: 42 U.S.C. 7384q(b). 42 U.S.C.
7384l(14)(C).
John Howard,
Director, National Institute for Occupational
Safety and Health.
[FR Doc. 2016–04415 Filed 2–29–16; 8:45 am]
BILLING CODE 4163–19–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Office of the Secretary
Request for Information on Updates to
the ONC Voluntary Personal Health
Record Model Privacy Notice
Office of the National
Coordinator for Health Information
Technology, Department of Health and
Human Services.
ACTION: Notice with comment; request
for information.
asabaliauskas on DSK5VPTVN1PROD with NOTICES
AGENCY:
The Office of the National
Coordinator for Health Information
Technology (ONC) seeks comments on
the scope and content of the voluntary
SUMMARY:
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20:18 Feb 29, 2016
Jkt 238001
Personal Health Record Model Privacy
Notice (MPN) developed by ONC and
published in 2011. In response to
stakeholder requests for an electronic
means to inform consumers about how
health technology products store, use,
and share health information (especially
products of health technology
developers not covered by the Health
Insurance Portability and
Accountability Act of 1996, Pub. L. 104–
191), we have initiated a process to
update the MPN to better align with the
current consumer health technology
landscape.
To be assured consideration,
electronic comments must be received
at one of the addresses provided below,
no later than 5 p.m. on April 15, 2016.
ADDRESSES: You may submit comments,
identified by MPN RFI, by either of the
following two methods (please do not
submit duplicate comments).
• ONC Web site: Follow the
instructions for submitting comments.
Attachments should be in Microsoft
Word, Microsoft Excel, or Adobe PDF;
however, we prefer Microsoft Word.
https://www.healthit.gov/policyresearchers-implementers/personalhealth-record-phr-model-privacy-notice.
• Email: ONCMPN@hhs.gov.
FOR FURTHER INFORMATION CONTACT:
Maya Uppaluru or Michael Lipinski,
202–690–7151.
SUPPLEMENTARY INFORMATION: In June
2008, the Office of the National
Coordinator for Health Information
Technology (ONC) began a multi-phase
and iterative project to develop an easyto-understand, voluntary Personal
Health Record (PHR) Model Privacy
Notice (MPN) that any PHR company
could adopt to communicate its
information practices to its users.
Developed in collaboration with the
Federal Trade Commission (FTC), the
project’s goals were two-fold: (1)
Increase consumers’ awareness of PHR
companies’ information practices; and
(2) empower consumers by providing
them with an easy way to compare the
information practices of two or more
PHR companies. The MPN was designed
to enable PHR companies to easily enter
their information practices and produce
a notice to allow consumers to quickly
learn and understand privacy and
security policies and information
practices, compare PHR company
practices, and make informed decisions.
Similar to the Food and Drug
Administration’s Nutrition Facts Label,
this approach did not mandate specific
policies, but rather was meant to
encourage user-friendly transparency of
a company’s existing practices.
DATES:
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The MPN has two sections: (1) The
‘‘Release’’ section; and (2) the ‘‘Secure’’
section. Both sections of the MPN
include model language that informs
consumers about how a PHR company
is using an individual’s health
information. The current MPN can be
found here, but we note that it is no
longer available for use. Additional
background on the MPN can be found
at: https://www.healthit.gov/policyresearchers-implementers/personalhealth-record-phr-model-privacy-notice.
Since the development of the MPN,
the consumer health technology
landscape has greatly evolved. More
consumers are now able to
electronically access their health
information than ever before. Not only
are consumers interacting with their
clinical and claims data (often collected
and maintained by health care providers
and health plans regulated under the
Health Insurance Portability and
Accountability Act of 1996 (HIPAA)
(i.e., ‘‘covered entities’’)), but they are
also interacting with fitness and
wellness data from devices offered by
health technology developers that may
not be regulated by HIPAA. In general,
HIPAA regulations govern how covered
entities and their business associates
maintain, access, use and disclose
individually identifiable health
information and protected health
information, otherwise known as
‘‘PHI’’.1 Specifically, the HIPAA
regulations include requirements for:
keeping information private in the
Privacy Rule,2 which also includes
notifying individuals about how their
PHI can be accessed, used, and
disclosed; 3 adopting administrative,
technical and physical safeguards to
secure electronic PHI; 4 and mandating
notice to affected individuals when a
breach of PHI occurs.5 Health
technology developers that may not be
covered by HIPAA are often called
‘‘non-covered entities’’ or ‘‘NCEs.’’
Health technology developers make
available a diverse array of products,
including mobile apps, wearable
devices, and sensors, and often display
notices of their privacy and information
practices to consumers. These
developers may be subject to other
federal laws, including the FTC Act’s
prohibition on unfair or deceptive acts
or practices,6 and the FTC’s Health
1 45
CFR 160.103.
CFR 164.501 et seq.
3 45 CFR 164.520; see also Office of Civil Rights
Model Notices of Privacy Practices: https://
www.hhs.gov/hipaa/for-professionals/privacy/
guidance/model-notices-privacy-practices/.
4 45 CFR 164.301 et seq.
5 45 CFR 164.400–414.
6 15 U.S.C. 45(a) (Section 5 of the FTC Act).
2 45
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Agencies
[Federal Register Volume 81, Number 40 (Tuesday, March 1, 2016)]
[Notices]
[Pages 10633-10634]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2016-04415]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
Designation of a Class of Employees for Addition to the Special
Exposure Cohort
AGENCY: National Institute for Occupational Safety and Health (NIOSH),
Centers for Disease Control and Prevention, Department of Health and
Human Services (HHS).
ACTION: Notice.
-----------------------------------------------------------------------
SUMMARY: HHS gives notice of a decision to designate a class of
employees from the Battelle Laboratories--King Avenue site in
[[Page 10634]]
Columbus, Ohio, as an addition to the Special Exposure Cohort (SEC)
under the Energy Employees Occupational Illness Compensation Program
Act of 2000.
FOR FURTHER INFORMATION CONTACT: Stuart L. Hinnefeld, Director,
Division of Compensation Analysis and Support, NIOSH, 1090 Tusculum
Avenue, MS C-46, Cincinnati, OH 45226-1938, Telephone 1-877-222-7570.
Information requests can also be submitted by email to DCAS@CDC.GOV.
SUPPLEMENTARY INFORMATION: On February 18, 2016, as provided for under
42 U.S.C. 7384l(14)(C),the Secretary of HHS designated the following
class of employees as an addition to the SEC:
All Atomic Weapons Employees who worked at the facility owned by
the Battelle Laboratories at the King Avenue site in Columbus, Ohio,
during the period from July 1, 1956, through December 31, 1970, for
a number of work days aggregating at least 250 work days, occurring
either solely under this employment, or in combination with work
days within the parameters established for one or more other classes
of employees included in the Special Exposure Cohort.
This designation will become effective on March 19, 2016, unless
Congress provides otherwise prior to the effective date. After this
effective date, HHS will publish a notice in the Federal Register
reporting the addition of this class to the SEC or the result of any
provision by Congress regarding the decision by HHS to add the class to
the SEC.
Authority: 42 U.S.C. 7384q(b). 42 U.S.C. 7384l(14)(C).
John Howard,
Director, National Institute for Occupational Safety and Health.
[FR Doc. 2016-04415 Filed 2-29-16; 8:45 am]
BILLING CODE 4163-19-P