Office of the Director; Amended Notice of Meeting, 81554 [2015-32768]

Download as PDF mstockstill on DSK4VPTVN1PROD with NOTICES 81554 Federal Register / Vol. 80, No. 250 / Wednesday, December 30, 2015 / Notices Center Drive, Mail Stop 9702, Rockville, MD 20850–9702, Tel. 240–276–5515 or email ncitechtransfer@mail.nih.gov. FOR FURTHER INFORMATION CONTACT: Information on licensing and codevelopment research collaborations, and copies of the U.S. patent applications listed below, may be obtained by contacting: Attn. Invention Development and Marketing Unit, Technology Transfer Center, National Cancer Institute, 9609 Medical Center Drive, Mail Stop 9702, Rockville, MD 20850–9702, Tel. 240–276–5515 or email ncitechtransfer@mail.nih.gov. A signed Confidential Disclosure Agreement may be required to receive copies of the patent applications. SUPPLEMENTARY INFORMATION: Title of invention: Thalidomide/ lenolidomide/pomalidomide analogs that inhibit inflammation, angiogenesis. Description of Technology: Thalidomide and its close analogs (lenalidomide and pomalidomide) are widely used to treat a variety of diseases, such as multiple myeloma and other cancers, as well as the symptoms of several inflammatory disorders. However, thalidomide is known for its teratogenic adverse effects when first introduced clinically in the 1950s, and is associated with drowsiness and peripheral neuropathy. Hence, there is intense interest to synthesize, identify and develop safer analogs. Researchers at the National Institute on Aging’s Drug Design and Development Section synthesized novel thalidomide analogs that demonstrate clinical potential without being teratogenic, as initially evaluated in in vivo zebrafish and chicken embryo model systems and in cell culture. These new compounds differentially provide potent antiangiogenesis and/or anti-inflammatory action. The agents have potential for development of new cancer therapies and treatment of a number of neurological and systemic disorders involving chronic inflammation and elevated TNF-alpha levels. Potential Commercial Applications: —Cancer therapeutics —Inflammatory disorders such as Crohn’s disease, sarcoidosis, graftversus-host disease, and rheumatoid arthritis —Neuroinflammatory disorders (acute: Traumatic brain injury and stroke; chronic: Parkinson’s disease, Alzheimer’s disease, multiple sclerosis) Value Proposition: —Non-teratogenic —Potent Development Stage: VerDate Sep<11>2014 17:59 Dec 29, 2015 Jkt 238001 In Vitro/Discovery Inventor(s): Nigel H. Greig (NIA), Weiming Luo (NIA), David Tweedie (NIA), William Douglas Figg, Sr. (NCI), Neil Vargesson (Univ. Aberdeen, Scotland), and Shaunna Beedie (NCI & Univ. Aberdeen, Scotland) Intellectual Property: HHS Reference No. E–208–2015/0–US– 01 U.S. Provisional Patent Application No. 62/235, 105, filed September 30, 2015, entitled ‘‘Thalidomide/ lenolidomide/pomalidomide analogs that inhibit inflammation, angiogenesis’’ Licensing and Collaborative/CoDevelopment Research Opportunity: The National Institute on Aging seeks collaborators to license or co-develop novel thalidomide analogs that demonstrate clinical potential without being teratogenic. Contact Information: Requests for copies of the patent application or inquiries about licensing and/or research collaboration and codevelopment opportunities should be sent to John D. Hewes, Ph.D., email: john.hewes@nih.gov. CFR Citation: 35 U.S.C. 209 and 37 CFR part 404 Dated: December 22, 2015. Thomas M. Stackhouse, Associate Director, Technology Transfer Center, National Cancer Institute. [FR Doc. 2015–32877 Filed 12–29–15; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is hereby given of the following meeting. The meeting will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The contract proposals and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the contract proposals, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Rodent Tissue Bank. PO 00000 Frm 00048 Fmt 4703 Sfmt 4703 Date: January 29, 2016. Time: 12:30 p.m. to 2:00 p.m. Agenda: To review and evaluate contract proposals. Place: National Institute on Aging, Gateway Building, Suite 2C212, 7201 Wisconsin Avenue, Bethesda, MD 20892 (Telephone Conference Call). Contact Person: Kimberly Firth, Ph.D., National Institutes of Health, National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue, Suite 2C212, Bethesda, MD 20892, 301–402–7702 firthkm@ mail.nih.gov. (Catalogue of Federal Domestic Assistance Program Nos. 93.866, Aging Research, National Institutes of Health, HHS) Dated: December 23, 2015. Melanie J. Gray, Program Analyst, Office of Federal Advisory Committee Policy. [FR Doc. 2015–32772 Filed 12–29–15; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Office of the Director; Amended Notice of Meeting Notice is hereby given of a correction in the meeting notice of the Big Data to Knowledge Multi-Council Working Group (BD2K) that was published in the Federal Register on Friday, December 11, 2015, 80 FRN 76996. The date of the meeting is January 11, 2016. The time and meeting access codes remain the same. A portion of the meeting is open to the public, 11 a.m. to 12:00 p.m. and is being held by teleconference only. No physical meeting location is provided for any interested individuals to listen to committee discussions. Any individual interested in listening to the meeting discussions must call: 1–866– 692–3158 and use Passcode 2956317 for access to the meeting. Dated: December 23, 2015. Anna Snouffer, Deputy Director, Office of Federal Advisory Committee Policy. [FR Doc. 2015–32768 Filed 12–29–15; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Biomedical Imaging and Bioengineering; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as E:\FR\FM\30DEN1.SGM 30DEN1

Agencies

[Federal Register Volume 80, Number 250 (Wednesday, December 30, 2015)]
[Notices]
[Page 81554]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2015-32768]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Office of the Director; Amended Notice of Meeting

    Notice is hereby given of a correction in the meeting notice of the 
Big Data to Knowledge Multi-Council Working Group (BD2K) that was 
published in the Federal Register on Friday, December 11, 2015, 80 FRN 
76996.
    The date of the meeting is January 11, 2016. The time and meeting 
access codes remain the same.
    A portion of the meeting is open to the public, 11 a.m. to 12:00 
p.m. and is being held by teleconference only. No physical meeting 
location is provided for any interested individuals to listen to 
committee discussions. Any individual interested in listening to the 
meeting discussions must call: 1-866-692-3158 and use Passcode 2956317 
for access to the meeting.

    Dated: December 23, 2015.
Anna Snouffer,
Deputy Director, Office of Federal Advisory Committee Policy.
[FR Doc. 2015-32768 Filed 12-29-15; 8:45 am]
BILLING CODE 4140-01-P

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