The Twentieth Food and Drug Administration International Separation Science Society Symposium on the Interface of Regulatory and Analytical Sciences for Biotechnology Health Products-WCBP 2016, 78742-78743 [2015-31691]
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Federal Register / Vol. 80, No. 242 / Thursday, December 17, 2015 / Notices
establishment to be removed from
FDA’s routine inspection work plan for
1 year from the last day of the ISO
13485:2003 audit. The voluntary
submitted ISO 13485:2003 audit report
provides FDA some information on the
conformance of the manufacturer with
basic and fundamental quality
management system requirements for
medical devices.
In 2012, FDA started working on the
MDSAP with other global regulators
within the International Medical Device
Regulators Forum (IMDRF) for purposes
of leveraging work performed for other
medical device regulators to meet its
inspection obligations. On November
15, 2013 (78 FR 68853), FDA announced
its participation within the MDSAP
consortium’s pilot program, which is
effective January 1, 2014, through
December 31, 2016.
After review of the MDSAP Mid-Pilot
Report, which published in August 2015
(Ref. 2), FDA announced that it will
participate with the other MDSAP
Consortium regulators from Australia,
Brazil, Canada, and Japan in the
implementation of the operational phase
of the program starting January 1, 2017.
The MDSAP program provides FDA
better assurances than the ISO
13485:2003 Voluntary Audit Report
Submission Pilot because FDA’s
requirements under 21 CFR 820 or other
FDA regulations typically covered
during FDA inspections are
encompassed within the MDSAP audit
model.
On January 1, 2017, MDSAP will
become fully operational to include
opening applications for additional
auditing organizations beyond the
limited eligible auditing organizations
within the pilot phase. Each regulator
within the consortium has committed to
continuing to utilize the MDSAP audits
during the pilot as well as during the
operational phase as described in the
MDSAP public announcements posted
on FDA’s Web page (Ref. 3).
Also, Health Canada in a recent
announcement laid out the timeframe
for which they will terminate their
Canadian Medical Device Conformity
Assessment System (CMDCAS) program
and utilize MDSAP as the means by
which manufacturers will obtain a
medical device license for distribution
of medical devices in Canada (Ref. 4).
As a result of the implementation of the
MDSAP program, FDA will no longer
accept ISO 13485:2003 Voluntary Audit
Report Submissions after March 31,
2016, to assist transitioning
manufacturers over to MDSAP.
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16:53 Dec 16, 2015
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II. References
The following references are on
display in the Division of Dockets
Management (HFA–305), Food and Drug
Administration, 5630 Fishers Lane, Rm.
1061, Rockville, MD 20852 and are
available for viewing by interested
persons between 9 a.m. and 4 p.m.,
Monday through Friday; they are also
available electronically at https://
www.regulations.gov. FDA has verified
the Web site addresses, as of the date
this document publishes in the Federal
Register, but Web sites are subject to
change over time.
1. FDA Guidance, Guidance for Industry,
Third Parties and Food and Drug
Administration Staff: Medical Device ISO
13485:2003 Voluntary Audit Report Pilot
Program, available at https://www.fda.gov/
downloads/MedicalDevices/
DeviceRegulationandGuidance/
GuidanceDocuments/UCM212798.pdf.
2. Medical Device Single Audit Program
(MDSAP) Mid-Pilot Status Report, January
2014–December 2016, available https://
www.fda.gov/downloads/MedicalDevices/
InternationalPrograms/MDSAPPilot/
UCM461661.pdf.
3. Medical Device Single Audit Program
(MDSAP) Pilot, available at https://
www.fda.gov/MedicalDevices/
InternationalPrograms/MDSAPPilot/.
4. Health Canada’s transition strategy from
CMDCAS to MDSAP, available at https://
www.hc-sc.gc.ca/dhp-mps/md-im/activit/int/
index-eng.php.
Dated: December 8, 2015.
Leslie Kux,
Associate Commissioner for Policy.
[FR Doc. 2015–31692 Filed 12–16–15; 8:45 am]
BILLING CODE 4164–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Food and Drug Administration
[Docket No.FDA–2015–N–0001]
The Twentieth Food and Drug
Administration International
Separation Science Society
Symposium on the Interface of
Regulatory and Analytical Sciences for
Biotechnology Health Products—
WCBP 2016
AGENCY:
Food and Drug Administration,
HHS.
ACTION:
I. Background
CASSS is a scientific society
providing forums for the dissemination
of information and discussions among
industry, academic and regulatory
professionals founded on the
development and applications of
separation science. This cosponsored
meeting provides state-of-the-art
presentations on the technologies used
to produce and assess product quality of
biotechnology-derived drug products.
II. Registration and Accommodations
A. Registration
There is a registration fee to attend
this meeting. The registration fee is
charged to help defray the costs of
programming and facilities. Seats are
limited, and registration will be on a
first-come, first-served basis.
To register, please complete
registration online at https://
www.casss.org/?WCBP1600. (FDA has
verified the Web address, but FDA is not
responsible for subsequent changes to
the Web site after this document
publishes in the Federal Register.) The
costs of registration for the different
categories of attendees are as follows:
Category
Industry Representatives.
Academic ...........
Government .......
Notice of meeting.
The Food and Drug
Administration’s (FDA) Center for Drug
Evaluation and Research, in
cosponsorship with the International
Separation Science Society (CASSS), is
announcing a meeting entitled ‘‘The
Twentieth FDA CASSS Symposium on
the Interface of Regulatory and
SUMMARY:
PO 00000
Analytical Sciences for Biotechnology
Health Products—WCBP 2016.’’ The
purpose of the meeting is to discuss
development of biotechnology-derived
drug products and analytic
methodologies for the development of
biotechnology-derived drug products.
DATES: The meeting will be held January
26, 2016, from 8 a.m., until January 28,
2016, at 5 p.m.
ADDRESSES: The meeting will be held at
The Mayflower Hotel, 1127 Connecticut
Ave. NW., Washington, DC
FOR FURTHER INFORMATION CONTACT:
Linda Mansouria, CASSS, 5900 Hollis
St., Suite R3, Emeryville, CA 94608,
510–428–0740, FAX: 510–428–0741,
lmansouria@casss.org.
SUPPLEMENTARY INFORMATION:
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Cost
$1995 (early bird);
$2395 (onsite).
$795 (early bird);
$895 (onsite).
$795 (early bird);
$895 (onsite).
B. Accommodations
Attendees are responsible for their
own hotel accommodations. Attendees
making reservations at the Mayflower
Hotel in Washington DC are eligible for
a reduced rate of $295 USD, not
including applicable taxes. To receive
the reduced rate, contact the Mayflower
E:\FR\FM\17DEN1.SGM
17DEN1
Federal Register / Vol. 80, No. 242 / Thursday, December 17, 2015 / Notices
Hotel (1–877–212–5752) and identify
yourself as an attendee of ‘‘CASSS—
WCBP 2016.’’ If you need special
accommodations due to a disability,
please contact Linda Mansouria (see FOR
FURTHER INFORMATION CONTACT) at least 7
days in advance.
III. Transcripts
We expect that transcripts will be
available approximately 30 days after
the meeting. A transcript will be
available in either hard copy or on CD–
ROM, after submission of a Freedom of
Information request. Send written
requests to the Division of Freedom of
Information (ELEM–1029), Food and
Drug Administration, 12420 Parklawn
Dr., Element Bldg., Rockville, MD
20857. Send faxed requests to 301–827–
9267.
Dated: December 11, 2015.
Leslie Kux,
Associate Commissioner for Policy.
[FR Doc. 2015–31691 Filed 12–16–15; 8:45 am]
BILLING CODE 4164–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA–2015–D–4562]
Safety Assessment for Investigational
New Drug Application Safety
Reporting; Draft Guidance for Industry;
Availability
AGENCY:
Food and Drug Administration,
HHS.
ACTION:
Notice of availability.
The Food and Drug
Administration (FDA, we, or Agency) is
announcing the availability of a draft
guidance for industry entitled ‘‘Safety
Assessment for IND Safety Reporting.’’
The draft guidance provides
recommendations to sponsors on
developing a systematic approach to
investigational new drug application
(IND) safety reporting for human drugs
and biological products developed
under an IND. This draft guidance is a
follow-on to the guidance for industry
and investigators entitled ‘‘Safety
Reporting Requirements for INDs and
BA/BE Studies’’ that provides
recommendations for how sponsors of
INDs can identify and evaluate
important safety information that must
be submitted to FDA and all
participating investigators, including a
recommendation that sponsors develop
a safety assessment committee.
DATES: Although you can comment on
any guidance at any time (see 21 CFR
asabaliauskas on DSK5VPTVN1PROD with NOTICES
SUMMARY:
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16:53 Dec 16, 2015
Jkt 238001
10.115(g)(5)), to ensure that the Agency
considers your comment on this draft
guidance before it begins work on the
final version of the guidance, submit
either electronic or written comments
on the draft guidance by February 16,
2016. Submit comments on the
information collection issues under the
Paperwork Reduction Act of 1995 by
February 16, 2016.
ADDRESSES: You may submit comments
as follows:
Electronic Submissions
Submit electronic comments in the
following way:
• Federal eRulemaking Portal: https://
www.regulations.gov. Follow the
instructions for submitting comments.
Comments submitted electronically,
including attachments, to https://
www.regulations.gov will be posted to
the docket unchanged. Because your
comment will be made public, you are
solely responsible for ensuring that your
comment does not include any
confidential information that you or a
third party may not wish to be posted,
such as medical information, your or
anyone else’s Social Security number, or
confidential business information, such
as a manufacturing process. Please note
that if you include your name, contact
information, or other information that
identifies you in the body of your
comments, that information will be
posted on https://www.regulations.gov.
• If you want to submit a comment
with confidential information that you
do not wish to be made available to the
public, submit the comment as a
written/paper submission and in the
manner detailed (see ‘‘Written/Paper
Submissions’’ and ‘‘Instructions’’).
Written/Paper Submissions
Submit written/paper submissions as
follows:
• Mail/Hand delivery/Courier (for
written/paper submissions): Division of
Dockets Management (HFA–305), Food
and Drug Administration, 5630 Fishers
Lane, Rm. 1061, Rockville, MD 20852.
• For written/paper comments
submitted to the Division of Dockets
Management, FDA will post your
comment, as well as any attachments,
except for information submitted,
marked and identified, as confidential,
if submitted as detailed in
‘‘Instructions.’’
Instructions: All submissions received
must include the Docket No. FDA–
2015–D–4562 for ‘‘Safety Assessment
for Investigational New Drug
Application Safety Reporting; Draft
Guidance for Industry; Availability.’’
Received comments will be placed in
the docket and, except for those
PO 00000
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78743
submitted as ‘‘Confidential
Submissions,’’ publicly viewable at
https://www.regulations.gov or at the
Division of Dockets Management
between 9 a.m. and 4 p.m., Monday
through Friday.
• Confidential Submissions—To
submit a comment with confidential
information that you do not wish to be
made publicly available, submit your
comments only as a written/paper
submission. You should submit two
copies total. One copy will include the
information you claim to be confidential
with a heading or cover note that states
‘‘THIS DOCUMENT CONTAINS
CONFIDENTIAL INFORMATION.’’ The
Agency will review this copy, including
the claimed confidential information, in
its consideration of comments. The
second copy, which will have the
claimed confidential information
redacted/blacked out, will be available
for public viewing and posted on https://
www.regulations.gov. Submit both
copies to the Division of Dockets
Management. If you do not wish your
name and contact information to be
made publicly available, you can
provide this information on the cover
sheet and not in the body of your
comments and you must identify this
information as ‘‘confidential.’’ Any
information marked as ‘‘confidential’’
will not be disclosed except in
accordance with 21 CFR 10.20 and other
applicable disclosure law. For more
information about FDA’s posting of
comments to public dockets, see 80 FR
56469, September 18, 2015, or access
the information at: https://www.fda.gov/
regulatoryinformation/dockets/
default.htm.
Docket: For access to the docket to
read background documents or the
electronic and written/paper comments
received, go to https://
www.regulations.gov and insert the
docket number, found in brackets in the
heading of this document, into the
‘‘Search’’ box and follow the prompts
and/or go to the Division of Dockets
Management, 5630 Fishers Lane, Rm.
1061, Rockville, MD 20852.
Submit comments on information
collection issues to the Office of
Management and Budget in the
following ways:
• Fax to the Office of Information and
Regulatory Affairs, OMB, Attn: FDA
Desk Officer, FAX: 202–395–7285, or
email to oira_submission@omb.eop.gov.
All comments should be identified with
the title ‘‘Safety Assessment for IND
Safety Reporting.’’
Submit written requests for single
copies of the draft guidance to the
Division of Drug Information, Center for
Drug Evaluation and Research, Food
E:\FR\FM\17DEN1.SGM
17DEN1
Agencies
[Federal Register Volume 80, Number 242 (Thursday, December 17, 2015)]
[Notices]
[Pages 78742-78743]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2015-31691]
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
Food and Drug Administration
[Docket No.FDA-2015-N-0001]
The Twentieth Food and Drug Administration International
Separation Science Society Symposium on the Interface of Regulatory and
Analytical Sciences for Biotechnology Health Products--WCBP 2016
AGENCY: Food and Drug Administration, HHS.
ACTION: Notice of meeting.
-----------------------------------------------------------------------
SUMMARY: The Food and Drug Administration's (FDA) Center for Drug
Evaluation and Research, in cosponsorship with the International
Separation Science Society (CASSS), is announcing a meeting entitled
``The Twentieth FDA CASSS Symposium on the Interface of Regulatory and
Analytical Sciences for Biotechnology Health Products--WCBP 2016.'' The
purpose of the meeting is to discuss development of biotechnology-
derived drug products and analytic methodologies for the development of
biotechnology-derived drug products.
DATES: The meeting will be held January 26, 2016, from 8 a.m., until
January 28, 2016, at 5 p.m.
ADDRESSES: The meeting will be held at The Mayflower Hotel, 1127
Connecticut Ave. NW., Washington, DC
FOR FURTHER INFORMATION CONTACT: Linda Mansouria, CASSS, 5900 Hollis
St., Suite R3, Emeryville, CA 94608, 510-428-0740, FAX: 510-428-0741,
lmansouria@casss.org.
SUPPLEMENTARY INFORMATION:
I. Background
CASSS is a scientific society providing forums for the
dissemination of information and discussions among industry, academic
and regulatory professionals founded on the development and
applications of separation science. This cosponsored meeting provides
state-of-the-art presentations on the technologies used to produce and
assess product quality of biotechnology-derived drug products.
II. Registration and Accommodations
A. Registration
There is a registration fee to attend this meeting. The
registration fee is charged to help defray the costs of programming and
facilities. Seats are limited, and registration will be on a first-
come, first-served basis.
To register, please complete registration online at https://www.casss.org/?WCBP1600. (FDA has verified the Web address, but FDA is
not responsible for subsequent changes to the Web site after this
document publishes in the Federal Register.) The costs of registration
for the different categories of attendees are as follows:
------------------------------------------------------------------------
Category Cost
------------------------------------------------------------------------
Industry Representatives.................. $1995 (early bird);
$2395 (onsite).
Academic.................................. $795 (early bird);
$895 (onsite).
Government................................ $795 (early bird);
$895 (onsite).
------------------------------------------------------------------------
B. Accommodations
Attendees are responsible for their own hotel accommodations.
Attendees making reservations at the Mayflower Hotel in Washington DC
are eligible for a reduced rate of $295 USD, not including applicable
taxes. To receive the reduced rate, contact the Mayflower
[[Page 78743]]
Hotel (1-877-212-5752) and identify yourself as an attendee of
``CASSS--WCBP 2016.'' If you need special accommodations due to a
disability, please contact Linda Mansouria (see FOR FURTHER INFORMATION
CONTACT) at least 7 days in advance.
III. Transcripts
We expect that transcripts will be available approximately 30 days
after the meeting. A transcript will be available in either hard copy
or on CD-ROM, after submission of a Freedom of Information request.
Send written requests to the Division of Freedom of Information (ELEM-
1029), Food and Drug Administration, 12420 Parklawn Dr., Element Bldg.,
Rockville, MD 20857. Send faxed requests to 301-827-9267.
Dated: December 11, 2015.
Leslie Kux,
Associate Commissioner for Policy.
[FR Doc. 2015-31691 Filed 12-16-15; 8:45 am]
BILLING CODE 4164-01-P