Workshop on Alternative Approaches for Identifying Acute Systemic Toxicity: Moving From Research to Regulatory Testing; Notice of Public Meeting; Registration Information, 47501 [2015-19379]

Download as PDF Federal Register / Vol. 80, No. 152 / Friday, August 7, 2015 / Notices 93.393, Cancer Cause and Prevention Research; 93.394, Cancer Detection and Diagnosis Research; 93.395, Cancer Treatment Research; 93.396, Cancer Biology Research; 93.397, Cancer Centers Support; 93.398, Cancer Research Manpower; 93.399, Cancer Control, National Institutes of Health, HHS) Dated: August 4, 2015. Melanie J. Gray, Program Analyst, Office of Federal Advisory Committee Policy. [FR Doc. 2015–19438 Filed 8–6–15; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Workshop on Alternative Approaches for Identifying Acute Systemic Toxicity: Moving From Research to Regulatory Testing; Notice of Public Meeting; Registration Information The National Toxicology Program (NTP) Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) announces the workshop ‘‘Alternative Approaches for Identifying Acute Systemic Toxicity: Moving from Research to Regulatory Testing.’’ Workshop attendees will discuss the state of the science of alternative approaches for identifying acute systemic toxicity and explore ways to facilitate their implementation. DATES: Meeting: September 24–25, 2015, from 9:00 a.m. to approximately 5:00 p.m. Eastern Daylight Time (EDT). Meeting Registration: Deadline is September 11, 2015. ADDRESSES: Meeting Location: Porter Neuroscience Conference Center, National Institutes of Health, Bethesda, MD 20892. Meeting Web page: The preliminary agenda, registration, and other meeting materials are at https://ntp.niehs.nih.gov/ go/atwksp-2015. FOR FURTHER INFORMATION CONTACT: Dr. Warren S. Casey, Director, NICEATM; email: warren.casey@nih.gov; telephone: (919) 316–4729. SUPPLEMENTARY INFORMATION: SUMMARY: tkelley on DSK3SPTVN1PROD with NOTICES Background Acute systemic toxicity tests, which evaluate the propensity of a substance to produce lethality when administered orally, dermally, or by inhalation, are the most commonly performed type of safety test worldwide. This workshop will explore and discuss alternative approaches that could replace, reduce, or refine the use of animals for VerDate Sep<11>2014 18:24 Aug 06, 2015 Jkt 235001 identifying chemicals that may cause acute systemic toxicity. During the workshop, participants will (1) review the regulatory guidelines to define when and how acute systemic toxicity data are used; (2) review the science of alternative approaches for identifying acute systemic toxicity, including mechanism-based models, in vitro and in silico approaches, and lower vertebrate and invertebrate models; and (3) identify mechanisms of acute toxicity for promoting development of adverse outcome pathways (AOPs) for acute toxicity. The workshop steering committee is comprised of members from government and nongovernment stakeholder organizations including NICEATM, Physicians Committee for Responsible Medicine, People for the Ethical Treatment of Animals International Science Consortium Ltd., The Dow Chemical Company, U.S. Environmental Protection Agency, and Rutgers University. Preliminary Agenda and Other Meeting Information A preliminary agenda and additional information are available at https:// ntp.niehs.nih.gov/go/atwksp-2015. Meeting and Registration This meeting is open to the public, free of charge, with attendance limited only by available meeting space. Individuals who plan to attend should register at https://ntp.niehs.nih.gov/go/ atwksp-2015 by September 11, 2015, to facilitate planning. Interested individuals are encouraged to visit this Web page to stay abreast of the most current information about the meeting. Visitor and security information for visitors to NIH is available at https:// www.nih.gov/about/visitor/index.htm. Individuals with disabilities who need accommodation to participate in this event should contact Dr. Elizabeth Maull at telephone: (919) 316–4668 or email: maull@niehs.nih.gov. TTY users should contact the Federal TTY Relay Service at (800) 877–8339. Requests should be made at least five business days in advance of the event. Background Information on NICEATM NICEATM conducts data analyses, workshops, independent validation studies, and other activities to assess new, revised, and alternative test methods and strategies. NICEATM also provides support for the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM). The ICCVAM Authorization Act of 2000 (42 U.S.C. 285l–3) provides authority for ICCVAM and NICEATM in PO 00000 Frm 00052 Fmt 4703 Sfmt 4703 47501 the development of alternative test methods. Information about NICEATM and ICCVAM is found at https:// ntp.niehs.nih.gov/go/niceatm and https://ntp.niehs.nih.gov/go/iccvam, respectively. Dated: August 3, 2015. John R. Bucher, Associate Director, National Toxicology Program. [FR Doc. 2015–19379 Filed 8–6–15; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES Substance Abuse and Mental Health Services Administration Center for Substance Abuse Prevention; Notice of Meeting Pursuant to Public Law 92–463, notice is hereby given for the meeting of the Substance Abuse and Mental Health Services Administration’s (SAMHSA) Center for Substance Abuse Prevention National Advisory Council (CSAP NAC) on August 26, 2015. The Council was established to advise the Secretary, Department of Health and Human Services (HHS); the Administrator, SAMHSA; and Center Director, CSAP concerning matters relating to the activities carried out by and through the Center and the policies respecting such activities. The meeting will be open to the public and will include discussion of the alignment of substance abuse and mental illness prevention within the context of overall healthcare, and CSAP program developments. The meeting will be held in Rockville, Maryland. Attendance by the public will be limited to the space available. Interested persons may present data, information, or views, orally or in writing, on issues pending before the Council. Written submissions should be forwarded to the contact person on or before one week prior to the meeting. Oral presentations from the public will be scheduled at the conclusion of the meeting. Individuals interested in making oral presentations are encouraged to notify the contact on or before one week prior to the meeting. Five minutes will be allotted for each presentation. To attend onsite, submit written or brief oral comments, or request special accommodations for persons with disabilities, please register at the SAMHSA Committees’ Web site, https://nac.samhsa.gov/Registration/ meetingsRegistration.aspx, or communicate with the CSAP Council’s E:\FR\FM\07AUN1.SGM 07AUN1

Agencies

[Federal Register Volume 80, Number 152 (Friday, August 7, 2015)]
[Notices]
[Page 47501]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2015-19379]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Workshop on Alternative Approaches for Identifying Acute Systemic 
Toxicity: Moving From Research to Regulatory Testing; Notice of Public 
Meeting; Registration Information

SUMMARY: The National Toxicology Program (NTP) Interagency Center for 
the Evaluation of Alternative Toxicological Methods (NICEATM) announces 
the workshop ``Alternative Approaches for Identifying Acute Systemic 
Toxicity: Moving from Research to Regulatory Testing.'' Workshop 
attendees will discuss the state of the science of alternative 
approaches for identifying acute systemic toxicity and explore ways to 
facilitate their implementation.

DATES: Meeting: September 24-25, 2015, from 9:00 a.m. to approximately 
5:00 p.m. Eastern Daylight Time (EDT).
    Meeting Registration: Deadline is September 11, 2015.

ADDRESSES: Meeting Location: Porter Neuroscience Conference Center, 
National Institutes of Health, Bethesda, MD 20892.
    Meeting Web page: The preliminary agenda, registration, and other 
meeting materials are at https://ntp.niehs.nih.gov/go/atwksp-2015.

FOR FURTHER INFORMATION CONTACT: Dr. Warren S. Casey, Director, 
NICEATM; email: warren.casey@nih.gov; telephone: (919) 316-4729.

SUPPLEMENTARY INFORMATION:

Background

    Acute systemic toxicity tests, which evaluate the propensity of a 
substance to produce lethality when administered orally, dermally, or 
by inhalation, are the most commonly performed type of safety test 
worldwide. This workshop will explore and discuss alternative 
approaches that could replace, reduce, or refine the use of animals for 
identifying chemicals that may cause acute systemic toxicity.
    During the workshop, participants will (1) review the regulatory 
guidelines to define when and how acute systemic toxicity data are 
used; (2) review the science of alternative approaches for identifying 
acute systemic toxicity, including mechanism-based models, in vitro and 
in silico approaches, and lower vertebrate and invertebrate models; and 
(3) identify mechanisms of acute toxicity for promoting development of 
adverse outcome pathways (AOPs) for acute toxicity. The workshop 
steering committee is comprised of members from government and 
nongovernment stakeholder organizations including NICEATM, Physicians 
Committee for Responsible Medicine, People for the Ethical Treatment of 
Animals International Science Consortium Ltd., The Dow Chemical 
Company, U.S. Environmental Protection Agency, and Rutgers University.

Preliminary Agenda and Other Meeting Information

    A preliminary agenda and additional information are available at 
https://ntp.niehs.nih.gov/go/atwksp-2015.

Meeting and Registration

    This meeting is open to the public, free of charge, with attendance 
limited only by available meeting space. Individuals who plan to attend 
should register at https://ntp.niehs.nih.gov/go/atwksp-2015 by September 
11, 2015, to facilitate planning. Interested individuals are encouraged 
to visit this Web page to stay abreast of the most current information 
about the meeting.
    Visitor and security information for visitors to NIH is available 
at https://www.nih.gov/about/visitor/index.htm. Individuals with 
disabilities who need accommodation to participate in this event should 
contact Dr. Elizabeth Maull at telephone: (919) 316-4668 or email: 
maull@niehs.nih.gov. TTY users should contact the Federal TTY Relay 
Service at (800) 877-8339. Requests should be made at least five 
business days in advance of the event.

Background Information on NICEATM

    NICEATM conducts data analyses, workshops, independent validation 
studies, and other activities to assess new, revised, and alternative 
test methods and strategies. NICEATM also provides support for the 
Interagency Coordinating Committee on the Validation of Alternative 
Methods (ICCVAM). The ICCVAM Authorization Act of 2000 (42 U.S.C. 285l-
3) provides authority for ICCVAM and NICEATM in the development of 
alternative test methods. Information about NICEATM and ICCVAM is found 
at https://ntp.niehs.nih.gov/go/niceatm and https://ntp.niehs.nih.gov/go/iccvam, respectively.

    Dated: August 3, 2015.
John R. Bucher,
Associate Director, National Toxicology Program.
[FR Doc. 2015-19379 Filed 8-6-15; 8:45 am]
BILLING CODE 4140-01-P
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