Assessment of Radiofrequency-Induced Heating in the Magnetic Resonance Environment for Multi-Configuration Passive Medical Devices; Draft Guidance for Industry and Food and Drug Administration Staff; Availability, 36996-36997 [2015-15833]
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Federal Register / Vol. 80, No. 124 / Monday, June 29, 2015 / Notices
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1,070
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[FR Doc. 2015–15859 Filed 6–26–15; 8:45 am]
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Jkt 235001
54
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[FR Doc. 2015–15889 Filed 6–26–15; 8:45 am]
BILLING CODE 4184–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA–2015–D–2104]
Assessment of RadiofrequencyInduced Heating in the Magnetic
Resonance Environment for MultiConfiguration Passive Medical
Devices; Draft Guidance for Industry
and Food and Drug Administration
Staff; Availability
AGENCY:
Food and Drug Administration,
HHS.
ACTION:
Notice.
The Food and Drug
Administration (FDA or Agency) is
announcing the availability of the draft
guidance entitled ‘‘Assessment of
Radiofrequency-Induced Heating in the
Magnetic Resonance (MR) Environment
for Multi-Configuration Passive Medical
SUMMARY:
PO 00000
Frm 00036
Fmt 4703
Sfmt 4703
Number of
responses per
respondent
1
1
Average
burden hours
per response
16
16
Total
burden hours
864
5296
Devices.’’ The purpose of this guidance
is to provide an assessment paradigm
for radiofrequency (RF)-induced heating
on, or near, multi-component, or multiconfiguration, passive medical devices
in the magnetic resonance environment.
This draft guidance is not final nor is it
in effect at this time.
DATES: Although you can comment on
any guidance at any time (see 21 CFR
10.115(g)(5)), to ensure that the Agency
considers your comment of this draft
guidance before it begins work on the
final version of the guidance, submit
either electronic or written comments
on the draft guidance by August 28,
2015.
An electronic copy of the
guidance document is available for
download from the Internet. See the
SUPPLEMENTARY INFORMATION section for
information on electronic access to the
guidance. Submit written requests for a
single hard copy of the draft guidance
document entitled ‘‘Assessment of
Radiofrequency-Induced Heating in the
Magnetic Resonance (MR) Environment
for Multi-Configuration Passive Medical
Devices’’ to the Office of the Center
Director, Guidance and Policy
Development, Center for Devices and
Radiological Health, Food and Drug
ADDRESSES:
E:\FR\FM\29JNN1.SGM
29JNN1
Federal Register / Vol. 80, No. 124 / Monday, June 29, 2015 / Notices
Administration, 10903 New Hampshire
Ave., Bldg. 66, Rm. 5431, Silver Spring,
MD 20993–0002. Send one selfaddressed adhesive label to assist that
office in processing your request.
Submit electronic comments on the
draft guidance to https://
www.regulations.gov. Submit written
comments to the Division of Dockets
Management (HFA–305), Food and Drug
Administration, 5630 Fishers Lane, Rm.
1061, Rockville, MD 20852. Identify
comments with the docket number
found in brackets in the heading of this
document.
FOR FURTHER INFORMATION CONTACT:
Wolfgang Kainz, Center for Devices and
Radiological Health, Food and Drug
Administration, 10903 New Hampshire
Ave., Bldg. 62, Rm. 1129, Silver Spring,
MD 20993–0002, 301–661–7595.
SUPPLEMENTARY INFORMATION:
I. Background
FDA is announcing the availability of
a draft guidance to provide an
assessment paradigm for RF-induced
heating on or near multi-component or
multi-configuration passive medical
devices in the MR environment. During
MR scanning, applied RF excitation
pulses induce currents that can cause
heating of electrically conductive
materials. RF-induced heating of
medical devices made with conductive
materials may lead to patient burns. To
minimize the risk of patient burns
during MR scanning, sponsors should
comprehensively assess devices in all
configurations and combinations.
However, multi-component passive
devices, such as orthopedic fixation
devices, may permit a very large number
of possible device configurations and
combinations of individual components.
Testing all possibilities may be
impracticable and unnecessary. This
draft guidance provides an approach to
identify a manageable number of device
configurations or combinations for the
testing of RF-induced heating in the MR
environment. Additionally, this draft
guidance provides recommendations on
how to assess RF-induced device
heating for multi-configuration passive
medical devices.
mstockstill on DSK4VPTVN1PROD with NOTICES
II. Significance of Guidance
This draft guidance is being issued
consistent with FDA’s good guidance
practices regulation (21 CFR 10.115).
The draft guidance, when finalized, will
represent the current thinking of FDA
on the assessment of RF-induced
heating of multi-component, or multiconfiguration, passive medical devices
in the MR environment. It does not
establish any rights for any person and
VerDate Sep<11>2014
17:13 Jun 26, 2015
Jkt 235001
is not binding on FDA or the public.
You can use an alternative approach if
it satisfies the requirements of the
applicable statutes and regulations.
III. Electronic Access
Persons interested in obtaining a copy
of the draft guidance may do so by
downloading an electronic copy from
the Internet. A search capability for all
Center for Devices and Radiological
Health guidance documents is available
at https://www.fda.gov/MedicalDevices/
DeviceRegulationandGuidance/
GuidanceDocuments/default.htm.
Guidance documents are also available
at https://www.regulations.gov. Persons
unable to download an electronic copy
of ‘‘Assessment of RadiofrequencyInduced Heating in the Magnetic
Resonance (MR) Environment for MultiConfiguration Passive Medical Devices’’
may send an email request to CDRHGuidance@fda.hhs.gov to receive an
electronic copy of the document. Please
use the document number 1500001 to
identify the guidance you are
requesting.
IV. Paperwork Reduction Act of 1995
This draft guidance refers to
previously approved collections of
information found in FDA regulations.
These collections of information are
subject to review by the Office of
Management and Budget (OMB) under
the Paperwork Reduction Act of 1995
(44 U.S.C. 3501–3520). The collections
of information in 21 CFR part 814 have
been approved under OMB control
number 0910–0231.
V. Comments
Interested persons may submit either
electronic comments regarding this
document to https://www.regulations.gov
or written comments to the Division of
Dockets Management (see ADDRESSES). It
is only necessary to send one set of
comments. Identify comments with the
docket number found in brackets in the
heading of this document. Received
comments may be seen in the Division
of Dockets Management between 9 a.m.
and 4 p.m., Monday through Friday, and
will be posted to the docket at https://
www.regulations.gov.
Dated: June 23, 2015.
Leslie Kux,
Associate Commissioner for Policy.
[FR Doc. 2015–15833 Filed 6–26–15; 8:45 am]
BILLING CODE 4164–01–P
PO 00000
36997
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Health Resources and Services
Administration
Notice of Publication of the Revised
Guidebook for the National Practitioner
Data Bank (NPDB)
Health Resources and Services
Administration (HRSA), HHS.
AGENCY:
ACTION:
Notice.
The National Practitioner
Data Bank (NPDB) announces the
release of the revised user Guidebook.
The NPDB is a confidential information
clearinghouse created by Congress and
intended to facilitate a comprehensive
review of the professional credentials of
health care practitioners, entities, and
suppliers. The Guidebook is the primary
policy document explaining the statutes
and regulations behind and operation of
the NPDB. It serves as an essential
reference for NPDB users, offering
reporting and querying examples,
explanations, definitions, and
frequently asked questions. The new
Guidebook incorporates legislative and
regulatory changes adopted since its last
edition, including the NPDB’s merger
with the Healthcare Integrity and
Protection Data Bank.
In November 2013, the Health
Resources and Services Administration
(HRSA) released a draft Guidebook to
the public for review and comment by
NPDB stakeholders and other interested
parties. It announced the draft
Guidebook’s availability in the Federal
Register. HRSA received more than 360
separate comments, consisting of
analyses of issues raised by the draft
Guidebook. The NPDB carefully studied
all comments received, and many led to
detailed analyses of how NPDB explains
its policies to its audiences. The final
Guidebook is now available at
www.npdb.hrsa.gov and replaces
previous Guidebooks.
SUMMARY:
FOR FURTHER INFORMATION CONTACT:
Ernia P. Hughes, MBA, Director of the
Division of Practitioner Data Bank,
Bureau of Health Workforce, Health
Resources and Services Administration
at: NPDBPolicy@hrsa.gov or 301–443–
2300.
Dated: June 18, 2015.
James Macrae,
Acting Administrator.
[FR Doc. 2015–15802 Filed 6–26–15; 8:45 am]
BILLING CODE 4165–15–P
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Agencies
[Federal Register Volume 80, Number 124 (Monday, June 29, 2015)]
[Notices]
[Pages 36996-36997]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2015-15833]
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA-2015-D-2104]
Assessment of Radiofrequency-Induced Heating in the Magnetic
Resonance Environment for Multi-Configuration Passive Medical Devices;
Draft Guidance for Industry and Food and Drug Administration Staff;
Availability
AGENCY: Food and Drug Administration, HHS.
ACTION: Notice.
-----------------------------------------------------------------------
SUMMARY: The Food and Drug Administration (FDA or Agency) is announcing
the availability of the draft guidance entitled ``Assessment of
Radiofrequency-Induced Heating in the Magnetic Resonance (MR)
Environment for Multi-Configuration Passive Medical Devices.'' The
purpose of this guidance is to provide an assessment paradigm for
radiofrequency (RF)-induced heating on, or near, multi-component, or
multi-configuration, passive medical devices in the magnetic resonance
environment. This draft guidance is not final nor is it in effect at
this time.
DATES: Although you can comment on any guidance at any time (see 21 CFR
10.115(g)(5)), to ensure that the Agency considers your comment of this
draft guidance before it begins work on the final version of the
guidance, submit either electronic or written comments on the draft
guidance by August 28, 2015.
ADDRESSES: An electronic copy of the guidance document is available for
download from the Internet. See the SUPPLEMENTARY INFORMATION section
for information on electronic access to the guidance. Submit written
requests for a single hard copy of the draft guidance document entitled
``Assessment of Radiofrequency-Induced Heating in the Magnetic
Resonance (MR) Environment for Multi-Configuration Passive Medical
Devices'' to the Office of the Center Director, Guidance and Policy
Development, Center for Devices and Radiological Health, Food and Drug
[[Page 36997]]
Administration, 10903 New Hampshire Ave., Bldg. 66, Rm. 5431, Silver
Spring, MD 20993-0002. Send one self-addressed adhesive label to assist
that office in processing your request.
Submit electronic comments on the draft guidance to https://www.regulations.gov. Submit written comments to the Division of Dockets
Management (HFA-305), Food and Drug Administration, 5630 Fishers Lane,
Rm. 1061, Rockville, MD 20852. Identify comments with the docket number
found in brackets in the heading of this document.
FOR FURTHER INFORMATION CONTACT: Wolfgang Kainz, Center for Devices and
Radiological Health, Food and Drug Administration, 10903 New Hampshire
Ave., Bldg. 62, Rm. 1129, Silver Spring, MD 20993-0002, 301-661-7595.
SUPPLEMENTARY INFORMATION:
I. Background
FDA is announcing the availability of a draft guidance to provide
an assessment paradigm for RF-induced heating on or near multi-
component or multi-configuration passive medical devices in the MR
environment. During MR scanning, applied RF excitation pulses induce
currents that can cause heating of electrically conductive materials.
RF-induced heating of medical devices made with conductive materials
may lead to patient burns. To minimize the risk of patient burns during
MR scanning, sponsors should comprehensively assess devices in all
configurations and combinations. However, multi-component passive
devices, such as orthopedic fixation devices, may permit a very large
number of possible device configurations and combinations of individual
components. Testing all possibilities may be impracticable and
unnecessary. This draft guidance provides an approach to identify a
manageable number of device configurations or combinations for the
testing of RF-induced heating in the MR environment. Additionally, this
draft guidance provides recommendations on how to assess RF-induced
device heating for multi-configuration passive medical devices.
II. Significance of Guidance
This draft guidance is being issued consistent with FDA's good
guidance practices regulation (21 CFR 10.115). The draft guidance, when
finalized, will represent the current thinking of FDA on the assessment
of RF-induced heating of multi-component, or multi-configuration,
passive medical devices in the MR environment. It does not establish
any rights for any person and is not binding on FDA or the public. You
can use an alternative approach if it satisfies the requirements of the
applicable statutes and regulations.
III. Electronic Access
Persons interested in obtaining a copy of the draft guidance may do
so by downloading an electronic copy from the Internet. A search
capability for all Center for Devices and Radiological Health guidance
documents is available at https://www.fda.gov/MedicalDevices/DeviceRegulationandGuidance/GuidanceDocuments/default.htm. Guidance
documents are also available at https://www.regulations.gov. Persons
unable to download an electronic copy of ``Assessment of
Radiofrequency-Induced Heating in the Magnetic Resonance (MR)
Environment for Multi-Configuration Passive Medical Devices'' may send
an email request to CDRH-Guidance@fda.hhs.gov to receive an electronic
copy of the document. Please use the document number 1500001 to
identify the guidance you are requesting.
IV. Paperwork Reduction Act of 1995
This draft guidance refers to previously approved collections of
information found in FDA regulations. These collections of information
are subject to review by the Office of Management and Budget (OMB)
under the Paperwork Reduction Act of 1995 (44 U.S.C. 3501-3520). The
collections of information in 21 CFR part 814 have been approved under
OMB control number 0910-0231.
V. Comments
Interested persons may submit either electronic comments regarding
this document to https://www.regulations.gov or written comments to the
Division of Dockets Management (see ADDRESSES). It is only necessary to
send one set of comments. Identify comments with the docket number
found in brackets in the heading of this document. Received comments
may be seen in the Division of Dockets Management between 9 a.m. and 4
p.m., Monday through Friday, and will be posted to the docket at https://www.regulations.gov.
Dated: June 23, 2015.
Leslie Kux,
Associate Commissioner for Policy.
[FR Doc. 2015-15833 Filed 6-26-15; 8:45 am]
BILLING CODE 4164-01-P