Agency Information Collection Activities; Submission for Office of Management and Budget Review; Comment Request; State Enforcement Notifications, 29012-29013 [2015-12236]
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29012
Federal Register / Vol. 80, No. 97 / Wednesday, May 20, 2015 / Notices
The Agency finds that reviewing such
information is critical to achieving a
productive meeting.
The collection of information
described in the guidance reflects the
current and past practice of sponsors
and applicants to submit meeting
requests as amendments to INDs, NDAs,
and BLAs and to submit background
information prior to a scheduled
meeting. Agency regulations currently
permit such requests and recommend
the submission of an information
package before an end-of-phase 2
meeting (§§ 312.47(b)(1)(ii) and
(b)(1)(iv)) and a pre-NDA meeting
(§ 312.47(b)(2)).
Description of Respondents: A
sponsor or applicant for a drug or
biological product who requests a
formal meeting with the Agency
regarding the development and review
of a PDUFA product.
Burden Estimate: Provided in this
document is an estimate of the annual
reporting burden for the submission of
meeting requests and information
packages under the guidance.
III. Request for a Formal Meeting
Based on data collected from the
review divisions and offices within
CDER and CBER, FDA estimates that
approximately 1,099 sponsors and
applicants (respondents) request
approximately 2,366 formal meetings
with CDER annually and approximately
175 respondents request approximately
264 formal meetings with CBER
annually regarding the development and
review of a PDUFA product. The hours
per response, which is the estimated
number of hours that a respondent
would spend preparing the information
to be submitted with a meeting request
in accordance with the guidance, is
estimated to be approximately 10 hours.
Based on FDA’s experience, the Agency
expects it will take respondents this
amount of time to gather and copy brief
statements about the product and a
description of the purpose and details of
the meeting.
IV. Information Package
Based on data collected from the
review divisions and offices within
CDER and CBER, FDA estimates that
approximately 959 respondents
submitted approximately 1,901
information packages to CDER annually
and approximately 142 respondents
submitted approximately 193
information packages to CBER annually
prior to a formal meeting regarding the
development and review of a PDUFA
product. The hours per response, which
is the estimated number of hours that a
respondent would spend preparing the
information package in accordance with
the guidance, is estimated to be
approximately 18 hours. Based on
FDA’s experience, the Agency expects it
will take respondents this amount of
time to gather and copy brief statements
about the product, a description of the
details for the anticipated meeting, and
data and information that generally
would already have been compiled for
submission to the Agency.
As stated earlier, the guidance
provides information on how the
Agency will interpret and apply section
119(a) of the FDAMA, specific PDUFA
goals for the management of meetings
associated with the review of human
drug applications for PDUFA products,
and provisions of existing regulations
describing certain meetings (§§ 312.47
and 312.82). The information collection
provisions in § 312.47 concerning endof-phase 2 meetings and pre-NDA
meetings have been approved by OMB
control number 0910–0014. However,
the guidance provides additional
recommendations for submitting
information to FDA in support of a
meeting request. As a result, FDA is
submitting for OMB approval these
additional estimates.
TABLE 1—ESTIMATED ANNUAL REPORTING BURDEN 1
Number of
respondents
Meeting requests and information packages
Meeting Requests:
CDER ............................................................................
CBER ............................................................................
Number of
responses per
respondent
Average
burden per
response
Total annual
responses
Total hours
1,099
175
2.15
1.51
2,366
264
10
10
23,660
2,640
Total .......................................................................
Information Packages:
CDER ............................................................................
CBER ............................................................................
........................
........................
........................
........................
26,300
959
142
1.99
1.36
1,901
193
18
18
34,218
3,474
Total .......................................................................
........................
........................
........................
........................
37,692
Grand Total ....................................................
........................
........................
........................
........................
63,992
1 There
are no capital costs or operating and maintenance costs associated with this collection of information.
Dated: May 14, 2015.
Leslie Kux,
Associate Commissioner for Policy.
[FR Doc. 2015–12170 Filed 5–19–15; 8:45 am]
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA–2008–N–0397]
Agency Information Collection
Activities; Submission for Office of
Management and Budget Review;
Comment Request; State Enforcement
Notifications
AGENCY:
Food and Drug Administration,
HHS.
ACTION:
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23:50 May 19, 2015
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Notice.
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The Food and Drug
Administration (FDA) is announcing
that a proposed collection of
information has been submitted to the
Office of Management and Budget
(OMB) for review and clearance under
the Paperwork Reduction Act of 1995.
SUMMARY:
Fax written comments on the
collection of information by June 19,
2015.
DATES:
To ensure that comments on
the information collection are received,
OMB recommends that written
comments be faxed to the Office of
Information and Regulatory Affairs,
ADDRESSES:
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29013
Federal Register / Vol. 80, No. 97 / Wednesday, May 20, 2015 / Notices
OMB, Attn: FDA Desk Officer, FAX:
202–395–7285, or emailed to oira_
submission@omb.eop.gov. All
comments should be identified with the
OMB control number 0910–0275. Also
include the FDA docket number found
in brackets in the heading of this
document.
FDA
PRA Staff, Office of Operations, Food
and Drug Administration, 8455
Colesville Rd.; COLE–14526, Silver
Spring, MD 20993–0002 PRAStaff@
fda.hhs.gov.
FOR FURTHER INFORMATION CONTACT:
In
compliance with 44 U.S.C. 3507, FDA
SUPPLEMENTARY INFORMATION:
has submitted the following proposed
collection of information to OMB for
review and clearance.
State Enforcement Notifications—21
CFR 100.2(d)
OMB Control Number 0910–0275—
Extension
Section 310(b) of the Federal Food,
Drug, and Cosmetic Act (the FD&C Act)
(21 U.S.C. 337(b)) authorizes a State to
enforce certain sections of the FD&C Act
in their own name and within their own
jurisdiction. However, before doing so,
a State must provide notice to FDA
according to 21 CFR 100.2. The
information required in a letter of
notification under § 100.2(d) enables us
to identify the food against which a
State intends to take action and to
advise that State whether Federal
enforcement action against the food has
been taken or is in process. With certain
narrow exceptions, Federal enforcement
action precludes State action under the
FD&C Act.
In the Federal Register of March 13,
2015 (80 FR 13392), FDA published a
60-day notice requesting public
comment on the proposed collection of
information. No comments were
received.
We estimate the burden of this
collection of information as follows:
TABLE 1—ESTIMATED ANNUAL REPORTING BURDEN 1
21 CFR section
Number of
respondents
Number of
responses per
respondents
Total annual
responses
Average
burden per
response
Total hours
100.2(d) ................................................................................
1
1
1
10
10
1 There
are no capital costs or operating and maintenance costs associated with this collection of information.
The estimated reporting burden for
§ 100.2(d) is minimal because
enforcement notifications are seldom
used by States. During the last 3 years,
we have not received any new
enforcement notifications; therefore, we
estimate that one or fewer notifications
will be submitted annually. Although
we have not received any new
enforcement notifications in the last 3
years, we believe these information
collection provisions should be
extended to provide for the potential
future need of a State government to
submit enforcement notifications
informing us when it intends to take
enforcement action under the FD&C Act
against a particular food located in the
State.
Dated: May 15, 2015.
Leslie Kux,
Associate Commissioner for Policy.
[FR Doc. 2015–12236 Filed 5–19–15; 8:45 am]
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
mstockstill on DSK4VPTVN1PROD with NOTICES
National Institutes of Health
National Institute of Neurological
Disorders and Stroke; Notice of Closed
Meetings
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. App.), notice is
hereby given of the following meetings.
The meetings will be closed to the
public in accordance with the
VerDate Sep<11>2014
23:50 May 19, 2015
Jkt 235001
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: National Institute of
Neurological Disorders and Stroke, Initial
Review Group, Neurological Sciences and
Disorders B.
Date: June 25–26, 2015.
Time: 8:00 a.m. to 6:00 p.m.
Agenda: To review and evaluate grant
applications.
Place: Wyndam Grand Chicago Riverfront
Hotel, 71 E. Wacker Drive, Chicago, IL 60601.
Contact Person: Birgit Neuhuber, Ph.D.,
Scientific Review Officer, Scientific Review
Branch, Division of Extramural Research,
NINDS/NIH/DHHS/Neuroscience Center,
6001 Executive Boulevard, Suite 3208, MSC
9529, Bethesda, MD 20892–9529, 301–496–
3562, neuhuber@ninds.nih.gov.
Name of Committee: Neurological Sciences
Training Initial Review Group, NST–2
Subcommittee.
Date: June 29–30, 2015.
Time: 8:00 a.m. to 4:00 p.m.
Agenda: To review and evaluate grant
applications.
Place: The Fairmont Washington, DC, 2401
M Street NW., Washington, DC 20037.
Contact Person: Elizabeth A. Webber,
Ph.D., Scientific Review Officer, Scientific
Review Branch, Division of Extramural
Research, NINDS/NIH/DHHS/Neuroscience
Center, 6001 Executive Boulevard, Suite
3208, MSC 9529, Bethesda, MD 20892–9529,
301–496–1917, webbere@mail.nih.gov.
PO 00000
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(Catalogue of Federal Domestic Assistance
Program Nos. 93.853, Clinical Research
Related to Neurological Disorders; 93.854,
Biological Basis Research in the
Neurosciences, National Institutes of Health,
HHS)
Dated: May 14, 2015.
Carolyn Baum,
Program Analyst, Office of Federal Advisory
Committee Policy.
[FR Doc. 2015–12125 Filed 5–19–15; 8:45 am]
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DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
Center for Scientific Review; Notice of
Closed Meetings
Pursuant to section 10(d) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. App.), notice is
hereby given of the following meetings.
The meetings will be closed to the
public in accordance with the
provisions set forth in sections
552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,
as amended. The grant applications and
the discussions could disclose
confidential trade secrets or commercial
property such as patentable material,
and personal information concerning
individuals associated with the grant
applications, the disclosure of which
would constitute a clearly unwarranted
invasion of personal privacy.
Name of Committee: Oncology 2—
Translational Clinical Integrated Review
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Agencies
[Federal Register Volume 80, Number 97 (Wednesday, May 20, 2015)]
[Notices]
[Pages 29012-29013]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2015-12236]
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA-2008-N-0397]
Agency Information Collection Activities; Submission for Office
of Management and Budget Review; Comment Request; State Enforcement
Notifications
AGENCY: Food and Drug Administration, HHS.
ACTION: Notice.
-----------------------------------------------------------------------
SUMMARY: The Food and Drug Administration (FDA) is announcing that a
proposed collection of information has been submitted to the Office of
Management and Budget (OMB) for review and clearance under the
Paperwork Reduction Act of 1995.
DATES: Fax written comments on the collection of information by June
19, 2015.
ADDRESSES: To ensure that comments on the information collection are
received, OMB recommends that written comments be faxed to the Office
of Information and Regulatory Affairs,
[[Page 29013]]
OMB, Attn: FDA Desk Officer, FAX: 202-395-7285, or emailed to
oira_submission@omb.eop.gov. All comments should be identified with the
OMB control number 0910-0275. Also include the FDA docket number found
in brackets in the heading of this document.
FOR FURTHER INFORMATION CONTACT: FDA PRA Staff, Office of Operations,
Food and Drug Administration, 8455 Colesville Rd.; COLE-14526, Silver
Spring, MD 20993-0002 PRAStaff@fda.hhs.gov.
SUPPLEMENTARY INFORMATION: In compliance with 44 U.S.C. 3507, FDA has
submitted the following proposed collection of information to OMB for
review and clearance.
State Enforcement Notifications--21 CFR 100.2(d)
OMB Control Number 0910-0275--Extension
Section 310(b) of the Federal Food, Drug, and Cosmetic Act (the
FD&C Act) (21 U.S.C. 337(b)) authorizes a State to enforce certain
sections of the FD&C Act in their own name and within their own
jurisdiction. However, before doing so, a State must provide notice to
FDA according to 21 CFR 100.2. The information required in a letter of
notification under Sec. 100.2(d) enables us to identify the food
against which a State intends to take action and to advise that State
whether Federal enforcement action against the food has been taken or
is in process. With certain narrow exceptions, Federal enforcement
action precludes State action under the FD&C Act.
In the Federal Register of March 13, 2015 (80 FR 13392), FDA
published a 60-day notice requesting public comment on the proposed
collection of information. No comments were received.
We estimate the burden of this collection of information as
follows:
Table 1--Estimated Annual Reporting Burden \1\
--------------------------------------------------------------------------------------------------------------------------------------------------------
Number of
21 CFR section Number of responses per Total annual Average burden Total hours
respondents respondents responses per response
--------------------------------------------------------------------------------------------------------------------------------------------------------
100.2(d)........................................................... 1 1 1 10 10
--------------------------------------------------------------------------------------------------------------------------------------------------------
\1\ There are no capital costs or operating and maintenance costs associated with this collection of information.
The estimated reporting burden for Sec. 100.2(d) is minimal
because enforcement notifications are seldom used by States. During the
last 3 years, we have not received any new enforcement notifications;
therefore, we estimate that one or fewer notifications will be
submitted annually. Although we have not received any new enforcement
notifications in the last 3 years, we believe these information
collection provisions should be extended to provide for the potential
future need of a State government to submit enforcement notifications
informing us when it intends to take enforcement action under the FD&C
Act against a particular food located in the State.
Dated: May 15, 2015.
Leslie Kux,
Associate Commissioner for Policy.
[FR Doc. 2015-12236 Filed 5-19-15; 8:45 am]
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