Agency Information Collection Activities; Proposed Collection; Comment Request; Generic Clearance for the Collection of Qualitative Data on Tobacco Products and Communications; Correction, 73079 [2014-28714]
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Federal Register / Vol. 79, No. 236 / Tuesday, December 9, 2014 / Notices
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Food and Drug Administration
Food and Drug Administration
[Docket No. FDA–2013–D–1275]
[Docket No. FDA–2014–N–0987]
Agency Information Collection
Activities; Proposed Collection;
Comment Request; Generic Clearance
for the Collection of Qualitative Data
on Tobacco Products and
Communications; Correction
AGENCY:
Food and Drug Administration,
HHS.
ACTION:
AGENCY:
Food and Drug Administration,
HHS.
ACTION:
Notice; correction.
The Food and Drug
Administration (FDA) is correcting a
document entitled ‘‘Agency Information
Collection Activities; Proposed
Collection; Comment Request; Generic
Clearance for the Collection of
Qualitative Data on Tobacco Products
and Communications’’ that appeared in
the Federal Register of August 1, 2014.
The document announced the generic
clearance for the collection of
qualitative data on tobacco products and
communications. The document was
published with the incorrect docket
number. This document corrects that
error.
FDA
PRA Staff, Office of Operations, Food
and Drug Administration, 8455
Colesville Rd., COLE–14526, Silver
Spring, MD 20993–0002,
PRAStaff@fda.hhs.gov.
FOR FURTHER INFORMATION CONTACT:
In FR Doc.
2014–18195, appearing on page 44779
in the Federal Register of August 1,
2014 (79 FR 44779), FDA is making the
following correction:
1. On page 44779, in the second
column, in the Docket No. heading,
‘‘FDA–2014–N–0005’’ is corrected to
read ‘‘FDA–2014–N–0987.’’
SUPPLEMENTARY INFORMATION:
Dated: December 3, 2014.
Leslie Kux,
Associate Commissioner for Policy.
[FR Doc. 2014–28714 Filed 12–8–14; 8:45 am]
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The Food and Drug
Administration (FDA) is announcing the
availability of a draft guidance for
industry entitled ‘‘General Clinical
Pharmacology Considerations for
Pediatric Studies for Drugs and
Biological Products.’’ The draft
guidance is intended to assist those
sponsors of new drug applications
(NDAs), biologics license applications
(BLAs) for therapeutic biologics, and
supplements to such applications who
are planning to conduct clinical studies
in pediatric populations. Effectiveness,
safety, or dose finding studies in
pediatric patients involve gathering
clinical pharmacology information, such
as information regarding a product’s
pharmacokinetics and
pharmacodynamics pertaining to dose
selection and individualization. This
draft guidance addresses general clinical
pharmacology considerations for
conducting studies so that the dosing
and safety information for drugs and
biologic products can be sufficiently
characterized, leading to well-designed
trials to evaluate effectiveness.
DATES: Although you can comment on
any guidance at any time (see 21 CFR
10.115(g)(5)), to ensure that the Agency
considers your comment on this draft
guidance before it begins work on the
final version of the guidance, submit
either electronic or written comments
on the draft guidance by February 9,
2015.
Submit written requests for
single copies of the draft guidance to the
Division of Drug Information, Center for
Drug Evaluation and Research, Food
and Drug Administration, 10001 New
Hampshire Ave., Hillandale Building,
4th Floor, Silver Spring, MD 20993.
Send one self-addressed adhesive label
to assist those offices in processing your
requests. See the SUPPLEMENTARY
INFORMATION section for electronic
access to the draft guidance document.
Submit electronic comments on the
draft guidance to https://
www.regulations.gov. Submit written
ADDRESSES:
PO 00000
comments to the Division of Dockets
Management (HFA–305), Food and Drug
Administration, 5630 Fishers Lane, Rm.
1061, Rockville, MD 20852.
FOR FURTHER INFORMATION CONTACT:
Gilbert J. Burckart, Center for Drug
Evaluation and Research, Food and
Drug Administration, 10903 New
Hampshire Ave., Bldg. 51, Rm. 3184,
Silver Spring, MD 20993–0002, 301–
796–2065.
SUPPLEMENTARY INFORMATION:
I. Background
Notice.
SUMMARY:
SUMMARY:
rljohnson on DSK3VPTVN1PROD with NOTICES
General Clinical Pharmacology
Considerations for Pediatric Studies
for Drugs and Biological Products;
Draft Guidance for Industry;
Availability
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Fmt 4703
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FDA is announcing the availability of
a draft guidance for industry entitled
‘‘General Clinical Pharmacology
Considerations for Pediatric Studies for
Drugs and Biological Products.’’ During
the past two decades, FDA has worked
to address the problem of inadequate
pediatric testing and inadequate
pediatric use information in drug and
biological product labeling. The Food
and Drug Administration Modernization
Act of 1997 (Pub. L. 105–115) addressed
the need for improved information
about drug use in the pediatric
population (codified at 21 U.S.C. 355a)
by establishing incentives for
conducting pediatric studies on drugs
while exclusivity or patent protection
exists. Congress subsequently passed
the Best Pharmaceuticals for Children
Act (BPCA) in 2002 and the Pediatric
Research Equity Act (PREA) in 2003.
Both BPCA and PREA were
reauthorized in 2007 and were made
permanent under Title V of the Food
and Drug Administration Safety and
Innovation Act of 2012 (Public Law
112–144).
Under BPCA, sponsors of certain
applications and supplements filed
under section 505 of the Federal Food,
Drug, and Cosmetic Act (21 U.S.C. 355)
(the FD&C Act) can obtain an additional
6 months of exclusivity if, in accordance
with the requirements of the statute, the
sponsor submits information responding
to a written request from the Secretary
relating to the use of a drug in the
pediatric population.
Under PREA, sponsors of certain
applications and supplements filed
under section 505 of the FD&C Act or
section 351 of the Public Health Service
Act are required to submit pediatric
assessments, unless they receive an
applicable waiver or deferral of this
requirement. If applicable, sponsors
must submit a request for a deferral or
waiver as part of an initial pediatric
study plan.
This draft guidance focuses on the
clinical pharmacology information (e.g.,
exposure-response, pharmacokinetics,
and pharmacodynamics) needed to
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09DEN1
Agencies
[Federal Register Volume 79, Number 236 (Tuesday, December 9, 2014)]
[Notices]
[Page 73079]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2014-28714]
[[Page 73079]]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA-2014-N-0987]
Agency Information Collection Activities; Proposed Collection;
Comment Request; Generic Clearance for the Collection of Qualitative
Data on Tobacco Products and Communications; Correction
AGENCY: Food and Drug Administration, HHS.
ACTION: Notice; correction.
-----------------------------------------------------------------------
SUMMARY: The Food and Drug Administration (FDA) is correcting a
document entitled ``Agency Information Collection Activities; Proposed
Collection; Comment Request; Generic Clearance for the Collection of
Qualitative Data on Tobacco Products and Communications'' that appeared
in the Federal Register of August 1, 2014. The document announced the
generic clearance for the collection of qualitative data on tobacco
products and communications. The document was published with the
incorrect docket number. This document corrects that error.
FOR FURTHER INFORMATION CONTACT: FDA PRA Staff, Office of Operations,
Food and Drug Administration, 8455 Colesville Rd., COLE-14526, Silver
Spring, MD 20993-0002, PRAStaff@fda.hhs.gov.
SUPPLEMENTARY INFORMATION: In FR Doc. 2014-18195, appearing on page
44779 in the Federal Register of August 1, 2014 (79 FR 44779), FDA is
making the following correction:
1. On page 44779, in the second column, in the Docket No. heading,
``FDA-2014-N-0005'' is corrected to read ``FDA-2014-N-0987.''
Dated: December 3, 2014.
Leslie Kux,
Associate Commissioner for Policy.
[FR Doc. 2014-28714 Filed 12-8-14; 8:45 am]
BILLING CODE 4164-01-P