Notice of NIH Pathways to Prevention Workshop: The Role of Opioids in the Treatment of Chronic Pain, 49332-49333 [2014-19804]

Download as PDF 49332 Federal Register / Vol. 79, No. 161 / Wednesday, August 20, 2014 / Notices To obtain a copy of the data collection plans and instruments or to request more information on the proposed project contact: DPCPSI, OD, NIH, Building 1, Room 260, 1 Center Drive, Bethesda, MD 20892; or call non-tollfree number 301–402–9852; or email the request, including address, to dpcpsi@ od.nih.gov. Requests for plans and instruments must be made in writing. Proposed Collection: Chimpanzee Research Use Form, 0925–NEW, Division of Program Coordination, Planning, and Strategic Initiatives (DPCPSI), Office of the Director (OD), National Institutes of Health (NIH). FOR FURTHER INFORMATION CONTACT: Chimpanzees in Biomedical and Behavioral Research: Assessing the Necessity, and as implemented through agency policy. The NIH, the CRUP, and/ or the Council will consider the information submitted through this form prior to the agency making funding decisions or otherwise allowing the research to begin. Completion of this form is a mandatory step toward receiving NIH support or approval for research involving chimpanzees. OMB approval is requested for 3 years. There are no costs to respondents other than their time. The total estimated annualized burden hours are 40. Need and Use of Information Collection: The purpose of this form is to obtain information needed by the NIH to assess whether proposed research triggers consideration by the Chimpanzee Research Use Panel (CRUP) and the NIH Council of Councils (Council), and if so, whether the research satisfies the agency’s policy for research involving chimpanzees. The CRUP is a working group of the Council that has been charged with considering whether research proposing to use chimpanzees is consistent with principles and criteria for research involving chimpanzees, as discussed in the 2011 Institute of Medicine report, ESTIMATED ANNUALIZED BURDEN HOURS Form name Type of respondent Number of respondents Number of responses per respondent Average time per response (in hours) Total annual burden hour Chimpanzee Research Use Form .... Research Community ....................... 20 1 2 40 Dated: August 14, 2014. Lawrence A. Tabak, Principal Deputy Director, NIH. [FR Doc. 2014–19820 Filed 8–19–14; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Notice of NIH Pathways to Prevention Workshop: The Role of Opioids in the Treatment of Chronic Pain Notice is hereby given of the National Institutes of Health (NIH) ‘‘Pathways to Prevention Workshop: The Role of Opioids in the Treatment of Chronic Pain,’’ which is open to the public. SUMMARY: The workshop will be held September 29–30, 2014. Sessions will begin at 8:30 a.m. on both days of the workshop. ADDRESSES: The workshop will be at the NIH Natcher Conference Center, 45 Center Drive, Bethesda, Maryland 20892. DATES: emcdonald on DSK67QTVN1PROD with NOTICES FOR FURTHER INFORMATION CONTACT: Registration and workshop information is available at the NIH Office of Disease Prevention Web site: https:// prevention.nih.gov/programs-events/ pathways-to-prevention/upcomingworkshops/opioids-chronic-pain; or by sending email to prevention@mail.nih.gov. Chronic pain is a major public health problem SUPPLEMENTARY INFORMATION: VerDate Mar<15>2010 16:44 Aug 19, 2014 Jkt 232001 that is estimated to affect more than 100 million people in the United States and about 20 to 30 percent of the population worldwide. The prevalence of persistent pain is expected to rise in the near future as the incidence of associated diseases (including diabetes, obesity, cardiovascular disorders, arthritis, and cancer) increases in the aging U.S. population. Opioids are powerful analgesics that are commonly used and found to be effective for many types of pain. However, opioids can produce significant side effects, including constipation, nausea, mental clouding, and respiratory depression, which can sometimes lead to death. In addition, long-term opioid use can also result in physical dependence, making it difficult to discontinue use even when the original cause of pain is no longer present. Furthermore, there is mounting evidence that long-term opioid use for pain can actually produce a chronic pain state, whereby patients find themselves in a vicious cycle in which opioids are used to treat pain caused by previous opioid use. Data from the Centers for Disease Control and Prevention indicate that the prescribing of opioids by clinicians has increased threefold in the last 20 years, contributing to the problem of prescription opioid abuse. Today, the number of people who die from prescription opioids exceeds the number of those who die from heroin and cocaine, combined. Health care providers are in a difficult position when treating moderate to severe chronic pain; opioid treatments PO 00000 Frm 00054 Fmt 4703 Sfmt 4703 may lessen the pain, but may also cause harm to patients. Additionally, there has not been adequate testing of opioids in terms of what types of pain they best treat, in what populations of people, and in what manner of administration. With insufficient data, and often inadequate training, many clinicians prescribe too much opioid treatment when lesser amounts of opioids or nonopioids would be effective. Alternatively, some health care providers avoid prescribing opioids altogether for fear of side effects and potential addiction, causing some patients to suffer needlessly. The 2014 ‘‘NIH Pathways to Prevention Workshop: The Role of Opioids in the Treatment of Chronic Pain’’ will seek to clarify: • Long-term effectiveness of opioids for treating chronic pain; • Potential risks of opioid treatment in various patient populations; • Effects of different opioid management strategies on outcomes related to addiction, abuse, misuse, pain, and quality of life; • Effectiveness of risk mitigation strategies for opioid treatment; and • Future research needs and priorities to improve the treatment of pain with opioids. The workshop is sponsored by the NIH Office of Disease Prevention and the NIH Pain Consortium. Initial planning for each Pathways to Prevention workshop is coordinated by a Working Group that nominates panelists and speakers and develops and finalizes questions that frame the workshop. After finalizing the E:\FR\FM\20AUN1.SGM 20AUN1 Federal Register / Vol. 79, No. 161 / Wednesday, August 20, 2014 / Notices questions, an evidence report is prepared by an Evidence-based Practice Center through a contract with the Agency for Healthcare Research and Quality (AHRQ). During the one-andone-half-day workshop, invited experts discuss the body of evidence, and attendees have opportunities to provide comments during open discussion periods. After weighing evidence from the evidence report, expert presentations, and public comments, an unbiased, independent panel will prepare a draft report that identifies research gaps and future research priorities. The draft report is posted on the ODP Web site, and public comments are accepted for two weeks. The final report is then released approximately two weeks later. Please Note: As part of the measures to ensure the safety of NIH employees, patients, visitors, and property, all visitors to the NIH Bethesda campus must be prepared to show a photo ID upon request. Visitors may be required to pass through a metal detector and have bags, backpacks, or purses inspected or x-rayed as they enter the campus. For more information about the security measures at the NIH, please visit the Web site at https:// www.nih.gov/about/visitorsecurity.htm. Dated: August 14, 2014. Lawrence A. Tabak, Principal Deputy Director, National Institutes of Health. [FR Doc. 2014–19804 Filed 8–19–14; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Office of the Director, National Institutes of Health; Notice of Meeting emcdonald on DSK67QTVN1PROD with NOTICES Pursuant to section 10(a) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is hereby given of a meeting of the Advisory Committee on Research on Women’s Health. The meeting will be open to the public, with attendance limited to space available. Individuals who plan to attend and need special assistance, such as sign language interpretation or other reasonable accommodations, should notify the Contact Person listed below in advance of the meeting. Name of Committee: Advisory Committee on Research on Women’s Health. Date: September 24, 2014. Time: 8:00 a.m. to 4:00 p.m. Agenda: The Committee serves to advise and make recommendations to the Director, Office of Research on Women’s Health (ORWH) on a broad range of topics including, the current scope of research on women’s VerDate Mar<15>2010 16:44 Aug 19, 2014 Jkt 232001 health and the influence of sex and gender on human health, efforts to understand the issues related to women in biomedical careers and their needs, and the current status of inclusion of women in clinical trials research. Place: National Institutes of Health, Building 31, Room 6C, 31 Center Drive, Bethesda, MD 20892. Contact Person: Susan E. Maier, Ph.D., Executive Secretary, NIH/OD/ORWH, 6707 Democracy Blvd., Room 400, Bethesda, MD 20852, 301–435–1573, maiers@mail.nih.gov. Any interested person may file written comments for the public record by submitting their comments at the following address: ACRWHComments@ sp10mail.nih.gov. Written comments only for the public record must not exceed two singlespaced, typed pages, using a 12-point typeface and 1 inch margins; it is preferred that the document be prepared in the MS Word® format. There will be an opportunity for public comments at the meeting. Written comments for those that would like to speak must still be presented prior to the meeting date. Each presenter will have a maximum of 5 minutes to present orally. The length of the comment period is restricted to 30 minutes which will allow for no more than 6 speakers. Speaker openings will be granted on a first come, first serve basis. Upon arrival at the meeting those that wish to speak and have previously submitted written comment may sign the special roster for speakers. Speakers on the special roster will speak in the order in which they sign in. There may not be time for all to speak. Public comments will be heard at the end of the meeting. Only testimony submitted to this email address and received in advance of the meeting are part of the official meeting record. Supplementary Information: A draft agenda for this meeting is posted at https:// orwh.od.nih.gov/about/acrwh/index.asp. The meeting will be live-video streamed at https://videocast.nih.gov/. Individuals who plan to attend the meeting in person are reminded that NIH has instituted stringent procedures for entrance onto the NIH campus. All visitor vehicles, including taxicabs, hotel, and airport shuttles will be inspected before being allowed on campus. Visitors will be asked to show one form of identification (for example, a government-issued photo ID, driver’s license, or passport) and to state the purpose of their visit. (Catalogue of Federal Domestic Assistance Program Nos. 93.14, Intramural Research Training Award; 93.22, Clinical Research Loan Repayment Program for Individuals from Disadvantaged Backgrounds; 93.232, Loan Repayment Program for Research Generally; 93.39, Academic Research Enhancement Award; 93.936, NIH Acquired Immunodeficiency Syndrome Research Loan Repayment Program; 93.187, Undergraduate Scholarship Program for Individuals from Disadvantaged Backgrounds, National Institutes of Health, HHS) PO 00000 Frm 00055 Fmt 4703 Sfmt 4703 49333 Dated: August 14, 2014. Carolyn Baum, Program Analyst, Office of Federal Advisory Committee Policy. [FR Doc. 2014–19682 Filed 8–19–14; 8:45 am] BILLING CODE 4140–01–P DEPARTMENT OF THE INTERIOR Fish and Wildlife Service [FWS–R4–R–2014–N169; FXRS12650400000S3–123–FF04R02000] Sam D. Hamilton Noxubee National Wildlife Refuge, Mississippi; Draft Comprehensive Conservation Plan and Environmental Assessment; Correction Fish and Wildlife Service, Interior. ACTION: Withdrawal of notice. AGENCY: On July 30, 2014, we, the U.S. Fish and Wildlife Service, announced the availability for public review and comment of a draft comprehensive conservation plan and environmental assessment (draft CCP/EA) for Sam D. Hamilton Noxubee National Wildlife Refuge in Mississippi. However, edits had not yet been completed on the draft CCP/EA, and the document is not yet ready for public review. We will publish a second Federal Register notice when the draft CCP/EA is ready for review. FOR FURTHER INFORMATION CONTACT: Steve Reagan, (662) 323–5548 x225, or Steve_Reagan@fws.gov. SUPPLEMENTARY INFORMATION: Pursuant to the National Wildlife Refuge System Improvement Act of 1997 (16 U.S.C. 668dd et seq.), U.S. Fish and Wildlife Service (Service) comprehensive conservation plan policy, and NEPA regulations (40 CFR 1506.6), we, the Service, announced the availability of a draft comprehensive conservation plan and environmental assessment (draft CCP/EA) for Sam D. Hamilton Noxubee National Wildlife Refuge in Oktibbeha, Winston, and Noxubee Counties, Mississippi, for public review and comment. This announcement published in the Federal Register on July 30, 2014 (79 FR 44188). However, edits had not yet been completed on the draft CCP/EA; therefore, the draft CCP/ EA is not yet ready for public review. We will publish a second Federal Register notice when the draft CCP/EA is ready for review, and open a comment period. SUMMARY: Authority This notice is published under the authority of the National Wildlife E:\FR\FM\20AUN1.SGM 20AUN1

Agencies

[Federal Register Volume 79, Number 161 (Wednesday, August 20, 2014)]
[Notices]
[Pages 49332-49333]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2014-19804]


-----------------------------------------------------------------------

DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Notice of NIH Pathways to Prevention Workshop: The Role of 
Opioids in the Treatment of Chronic Pain

SUMMARY: Notice is hereby given of the National Institutes of Health 
(NIH) ``Pathways to Prevention Workshop: The Role of Opioids in the 
Treatment of Chronic Pain,'' which is open to the public.

DATES: The workshop will be held September 29-30, 2014. Sessions will 
begin at 8:30 a.m. on both days of the workshop.

ADDRESSES: The workshop will be at the NIH Natcher Conference Center, 
45 Center Drive, Bethesda, Maryland 20892.

FOR FURTHER INFORMATION CONTACT: Registration and workshop information 
is available at the NIH Office of Disease Prevention Web site: https://prevention.nih.gov/programs-events/pathways-to-prevention/upcoming-workshops/opioids-chronic-pain; or by sending email to 
prevention@mail.nih.gov.

SUPPLEMENTARY INFORMATION: Chronic pain is a major public health 
problem that is estimated to affect more than 100 million people in the 
United States and about 20 to 30 percent of the population worldwide. 
The prevalence of persistent pain is expected to rise in the near 
future as the incidence of associated diseases (including diabetes, 
obesity, cardiovascular disorders, arthritis, and cancer) increases in 
the aging U.S. population.
    Opioids are powerful analgesics that are commonly used and found to 
be effective for many types of pain. However, opioids can produce 
significant side effects, including constipation, nausea, mental 
clouding, and respiratory depression, which can sometimes lead to 
death.
    In addition, long-term opioid use can also result in physical 
dependence, making it difficult to discontinue use even when the 
original cause of pain is no longer present. Furthermore, there is 
mounting evidence that long-term opioid use for pain can actually 
produce a chronic pain state, whereby patients find themselves in a 
vicious cycle in which opioids are used to treat pain caused by 
previous opioid use.
    Data from the Centers for Disease Control and Prevention indicate 
that the prescribing of opioids by clinicians has increased threefold 
in the last 20 years, contributing to the problem of prescription 
opioid abuse. Today, the number of people who die from prescription 
opioids exceeds the number of those who die from heroin and cocaine, 
combined.
    Health care providers are in a difficult position when treating 
moderate to severe chronic pain; opioid treatments may lessen the pain, 
but may also cause harm to patients. Additionally, there has not been 
adequate testing of opioids in terms of what types of pain they best 
treat, in what populations of people, and in what manner of 
administration. With insufficient data, and often inadequate training, 
many clinicians prescribe too much opioid treatment when lesser amounts 
of opioids or non-opioids would be effective. Alternatively, some 
health care providers avoid prescribing opioids altogether for fear of 
side effects and potential addiction, causing some patients to suffer 
needlessly.
    The 2014 ``NIH Pathways to Prevention Workshop: The Role of Opioids 
in the Treatment of Chronic Pain'' will seek to clarify:
     Long-term effectiveness of opioids for treating chronic 
pain;
     Potential risks of opioid treatment in various patient 
populations;
     Effects of different opioid management strategies on 
outcomes related to addiction, abuse, misuse, pain, and quality of 
life;
     Effectiveness of risk mitigation strategies for opioid 
treatment; and
     Future research needs and priorities to improve the 
treatment of pain with opioids.
    The workshop is sponsored by the NIH Office of Disease Prevention 
and the NIH Pain Consortium.
    Initial planning for each Pathways to Prevention workshop is 
coordinated by a Working Group that nominates panelists and speakers 
and develops and finalizes questions that frame the workshop. After 
finalizing the

[[Page 49333]]

questions, an evidence report is prepared by an Evidence-based Practice 
Center through a contract with the Agency for Healthcare Research and 
Quality (AHRQ). During the one-and-one-half-day workshop, invited 
experts discuss the body of evidence, and attendees have opportunities 
to provide comments during open discussion periods. After weighing 
evidence from the evidence report, expert presentations, and public 
comments, an unbiased, independent panel will prepare a draft report 
that identifies research gaps and future research priorities. The draft 
report is posted on the ODP Web site, and public comments are accepted 
for two weeks. The final report is then released approximately two 
weeks later.

    Please Note:  As part of the measures to ensure the safety of 
NIH employees, patients, visitors, and property, all visitors to the 
NIH Bethesda campus must be prepared to show a photo ID upon 
request. Visitors may be required to pass through a metal detector 
and have bags, backpacks, or purses inspected or x-rayed as they 
enter the campus. For more information about the security measures 
at the NIH, please visit the Web site at https://www.nih.gov/about/visitorsecurity.htm.


    Dated: August 14, 2014.
Lawrence A. Tabak,
Principal Deputy Director, National Institutes of Health.
[FR Doc. 2014-19804 Filed 8-19-14; 8:45 am]
BILLING CODE 4140-01-P
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