Notice of NIH Pathways to Prevention Workshop: The Role of Opioids in the Treatment of Chronic Pain, 49332-49333 [2014-19804]
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Federal Register / Vol. 79, No. 161 / Wednesday, August 20, 2014 / Notices
To
obtain a copy of the data collection
plans and instruments or to request
more information on the proposed
project contact: DPCPSI, OD, NIH,
Building 1, Room 260, 1 Center Drive,
Bethesda, MD 20892; or call non-tollfree number 301–402–9852; or email the
request, including address, to dpcpsi@
od.nih.gov. Requests for plans and
instruments must be made in writing.
Proposed Collection: Chimpanzee
Research Use Form, 0925–NEW,
Division of Program Coordination,
Planning, and Strategic Initiatives
(DPCPSI), Office of the Director (OD),
National Institutes of Health (NIH).
FOR FURTHER INFORMATION CONTACT:
Chimpanzees in Biomedical and
Behavioral Research: Assessing the
Necessity, and as implemented through
agency policy. The NIH, the CRUP, and/
or the Council will consider the
information submitted through this form
prior to the agency making funding
decisions or otherwise allowing the
research to begin. Completion of this
form is a mandatory step toward
receiving NIH support or approval for
research involving chimpanzees.
OMB approval is requested for 3
years. There are no costs to respondents
other than their time. The total
estimated annualized burden hours are
40.
Need and Use of Information
Collection: The purpose of this form is
to obtain information needed by the NIH
to assess whether proposed research
triggers consideration by the
Chimpanzee Research Use Panel (CRUP)
and the NIH Council of Councils
(Council), and if so, whether the
research satisfies the agency’s policy for
research involving chimpanzees. The
CRUP is a working group of the Council
that has been charged with considering
whether research proposing to use
chimpanzees is consistent with
principles and criteria for research
involving chimpanzees, as discussed in
the 2011 Institute of Medicine report,
ESTIMATED ANNUALIZED BURDEN HOURS
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respondents
Number of
responses per
respondent
Average time
per response
(in hours)
Total annual
burden hour
Chimpanzee Research Use Form ....
Research Community .......................
20
1
2
40
Dated: August 14, 2014.
Lawrence A. Tabak,
Principal Deputy Director, NIH.
[FR Doc. 2014–19820 Filed 8–19–14; 8:45 am]
BILLING CODE 4140–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
Notice of NIH Pathways to Prevention
Workshop: The Role of Opioids in the
Treatment of Chronic Pain
Notice is hereby given of the
National Institutes of Health (NIH)
‘‘Pathways to Prevention Workshop:
The Role of Opioids in the Treatment of
Chronic Pain,’’ which is open to the
public.
SUMMARY:
The workshop will be held
September 29–30, 2014. Sessions will
begin at 8:30 a.m. on both days of the
workshop.
ADDRESSES: The workshop will be at the
NIH Natcher Conference Center, 45
Center Drive, Bethesda, Maryland
20892.
DATES:
emcdonald on DSK67QTVN1PROD with NOTICES
FOR FURTHER INFORMATION CONTACT:
Registration and workshop information
is available at the NIH Office of Disease
Prevention Web site: https://
prevention.nih.gov/programs-events/
pathways-to-prevention/upcomingworkshops/opioids-chronic-pain; or by
sending email to
prevention@mail.nih.gov.
Chronic
pain is a major public health problem
SUPPLEMENTARY INFORMATION:
VerDate Mar<15>2010
16:44 Aug 19, 2014
Jkt 232001
that is estimated to affect more than 100
million people in the United States and
about 20 to 30 percent of the population
worldwide. The prevalence of persistent
pain is expected to rise in the near
future as the incidence of associated
diseases (including diabetes, obesity,
cardiovascular disorders, arthritis, and
cancer) increases in the aging U.S.
population.
Opioids are powerful analgesics that
are commonly used and found to be
effective for many types of pain.
However, opioids can produce
significant side effects, including
constipation, nausea, mental clouding,
and respiratory depression, which can
sometimes lead to death.
In addition, long-term opioid use can
also result in physical dependence,
making it difficult to discontinue use
even when the original cause of pain is
no longer present. Furthermore, there is
mounting evidence that long-term
opioid use for pain can actually produce
a chronic pain state, whereby patients
find themselves in a vicious cycle in
which opioids are used to treat pain
caused by previous opioid use.
Data from the Centers for Disease
Control and Prevention indicate that the
prescribing of opioids by clinicians has
increased threefold in the last 20 years,
contributing to the problem of
prescription opioid abuse. Today, the
number of people who die from
prescription opioids exceeds the
number of those who die from heroin
and cocaine, combined.
Health care providers are in a difficult
position when treating moderate to
severe chronic pain; opioid treatments
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Fmt 4703
Sfmt 4703
may lessen the pain, but may also cause
harm to patients. Additionally, there has
not been adequate testing of opioids in
terms of what types of pain they best
treat, in what populations of people,
and in what manner of administration.
With insufficient data, and often
inadequate training, many clinicians
prescribe too much opioid treatment
when lesser amounts of opioids or nonopioids would be effective.
Alternatively, some health care
providers avoid prescribing opioids
altogether for fear of side effects and
potential addiction, causing some
patients to suffer needlessly.
The 2014 ‘‘NIH Pathways to
Prevention Workshop: The Role of
Opioids in the Treatment of Chronic
Pain’’ will seek to clarify:
• Long-term effectiveness of opioids
for treating chronic pain;
• Potential risks of opioid treatment
in various patient populations;
• Effects of different opioid
management strategies on outcomes
related to addiction, abuse, misuse,
pain, and quality of life;
• Effectiveness of risk mitigation
strategies for opioid treatment; and
• Future research needs and priorities
to improve the treatment of pain with
opioids.
The workshop is sponsored by the
NIH Office of Disease Prevention and
the NIH Pain Consortium.
Initial planning for each Pathways to
Prevention workshop is coordinated by
a Working Group that nominates
panelists and speakers and develops
and finalizes questions that frame the
workshop. After finalizing the
E:\FR\FM\20AUN1.SGM
20AUN1
Federal Register / Vol. 79, No. 161 / Wednesday, August 20, 2014 / Notices
questions, an evidence report is
prepared by an Evidence-based Practice
Center through a contract with the
Agency for Healthcare Research and
Quality (AHRQ). During the one-andone-half-day workshop, invited experts
discuss the body of evidence, and
attendees have opportunities to provide
comments during open discussion
periods. After weighing evidence from
the evidence report, expert
presentations, and public comments, an
unbiased, independent panel will
prepare a draft report that identifies
research gaps and future research
priorities. The draft report is posted on
the ODP Web site, and public comments
are accepted for two weeks. The final
report is then released approximately
two weeks later.
Please Note: As part of the measures to
ensure the safety of NIH employees, patients,
visitors, and property, all visitors to the NIH
Bethesda campus must be prepared to show
a photo ID upon request. Visitors may be
required to pass through a metal detector and
have bags, backpacks, or purses inspected or
x-rayed as they enter the campus. For more
information about the security measures at
the NIH, please visit the Web site at https://
www.nih.gov/about/visitorsecurity.htm.
Dated: August 14, 2014.
Lawrence A. Tabak,
Principal Deputy Director, National Institutes
of Health.
[FR Doc. 2014–19804 Filed 8–19–14; 8:45 am]
BILLING CODE 4140–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
Office of the Director, National
Institutes of Health; Notice of Meeting
emcdonald on DSK67QTVN1PROD with NOTICES
Pursuant to section 10(a) of the
Federal Advisory Committee Act, as
amended (5 U.S.C. App.), notice is
hereby given of a meeting of the
Advisory Committee on Research on
Women’s Health.
The meeting will be open to the
public, with attendance limited to space
available. Individuals who plan to
attend and need special assistance, such
as sign language interpretation or other
reasonable accommodations, should
notify the Contact Person listed below
in advance of the meeting.
Name of Committee: Advisory Committee
on Research on Women’s Health.
Date: September 24, 2014.
Time: 8:00 a.m. to 4:00 p.m.
Agenda: The Committee serves to advise
and make recommendations to the Director,
Office of Research on Women’s Health
(ORWH) on a broad range of topics including,
the current scope of research on women’s
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16:44 Aug 19, 2014
Jkt 232001
health and the influence of sex and gender
on human health, efforts to understand the
issues related to women in biomedical
careers and their needs, and the current
status of inclusion of women in clinical trials
research.
Place: National Institutes of Health,
Building 31, Room 6C, 31 Center Drive,
Bethesda, MD 20892.
Contact Person: Susan E. Maier, Ph.D.,
Executive Secretary, NIH/OD/ORWH, 6707
Democracy Blvd., Room 400, Bethesda, MD
20852, 301–435–1573, maiers@mail.nih.gov.
Any interested person may file written
comments for the public record by
submitting their comments at the following
address: ACRWHComments@
sp10mail.nih.gov. Written comments only for
the public record must not exceed two singlespaced, typed pages, using a 12-point
typeface and 1 inch margins; it is preferred
that the document be prepared in the MS
Word® format. There will be an opportunity
for public comments at the meeting. Written
comments for those that would like to speak
must still be presented prior to the meeting
date. Each presenter will have a maximum of
5 minutes to present orally. The length of the
comment period is restricted to 30 minutes
which will allow for no more than 6
speakers. Speaker openings will be granted
on a first come, first serve basis. Upon arrival
at the meeting those that wish to speak and
have previously submitted written comment
may sign the special roster for speakers.
Speakers on the special roster will speak in
the order in which they sign in. There may
not be time for all to speak. Public comments
will be heard at the end of the meeting. Only
testimony submitted to this email address
and received in advance of the meeting are
part of the official meeting record.
Supplementary Information: A draft
agenda for this meeting is posted at https://
orwh.od.nih.gov/about/acrwh/index.asp. The
meeting will be live-video streamed at
https://videocast.nih.gov/.
Individuals who plan to attend the meeting
in person are reminded that NIH has
instituted stringent procedures for entrance
onto the NIH campus. All visitor vehicles,
including taxicabs, hotel, and airport shuttles
will be inspected before being allowed on
campus. Visitors will be asked to show one
form of identification (for example, a
government-issued photo ID, driver’s license,
or passport) and to state the purpose of their
visit.
(Catalogue of Federal Domestic Assistance
Program Nos. 93.14, Intramural Research
Training Award; 93.22, Clinical Research
Loan Repayment Program for Individuals
from Disadvantaged Backgrounds; 93.232,
Loan Repayment Program for Research
Generally; 93.39, Academic Research
Enhancement Award; 93.936, NIH Acquired
Immunodeficiency Syndrome Research Loan
Repayment Program; 93.187, Undergraduate
Scholarship Program for Individuals from
Disadvantaged Backgrounds, National
Institutes of Health, HHS)
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49333
Dated: August 14, 2014.
Carolyn Baum,
Program Analyst, Office of Federal Advisory
Committee Policy.
[FR Doc. 2014–19682 Filed 8–19–14; 8:45 am]
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DEPARTMENT OF THE INTERIOR
Fish and Wildlife Service
[FWS–R4–R–2014–N169;
FXRS12650400000S3–123–FF04R02000]
Sam D. Hamilton Noxubee National
Wildlife Refuge, Mississippi; Draft
Comprehensive Conservation Plan and
Environmental Assessment;
Correction
Fish and Wildlife Service,
Interior.
ACTION: Withdrawal of notice.
AGENCY:
On July 30, 2014, we, the U.S.
Fish and Wildlife Service, announced
the availability for public review and
comment of a draft comprehensive
conservation plan and environmental
assessment (draft CCP/EA) for Sam D.
Hamilton Noxubee National Wildlife
Refuge in Mississippi. However, edits
had not yet been completed on the draft
CCP/EA, and the document is not yet
ready for public review. We will publish
a second Federal Register notice when
the draft CCP/EA is ready for review.
FOR FURTHER INFORMATION CONTACT:
Steve Reagan, (662) 323–5548 x225, or
Steve_Reagan@fws.gov.
SUPPLEMENTARY INFORMATION: Pursuant
to the National Wildlife Refuge System
Improvement Act of 1997 (16 U.S.C.
668dd et seq.), U.S. Fish and Wildlife
Service (Service) comprehensive
conservation plan policy, and NEPA
regulations (40 CFR 1506.6), we, the
Service, announced the availability of a
draft comprehensive conservation plan
and environmental assessment (draft
CCP/EA) for Sam D. Hamilton Noxubee
National Wildlife Refuge in Oktibbeha,
Winston, and Noxubee Counties,
Mississippi, for public review and
comment. This announcement
published in the Federal Register on
July 30, 2014 (79 FR 44188). However,
edits had not yet been completed on the
draft CCP/EA; therefore, the draft CCP/
EA is not yet ready for public review.
We will publish a second Federal
Register notice when the draft CCP/EA
is ready for review, and open a
comment period.
SUMMARY:
Authority
This notice is published under the
authority of the National Wildlife
E:\FR\FM\20AUN1.SGM
20AUN1
Agencies
[Federal Register Volume 79, Number 161 (Wednesday, August 20, 2014)]
[Notices]
[Pages 49332-49333]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2014-19804]
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health
Notice of NIH Pathways to Prevention Workshop: The Role of
Opioids in the Treatment of Chronic Pain
SUMMARY: Notice is hereby given of the National Institutes of Health
(NIH) ``Pathways to Prevention Workshop: The Role of Opioids in the
Treatment of Chronic Pain,'' which is open to the public.
DATES: The workshop will be held September 29-30, 2014. Sessions will
begin at 8:30 a.m. on both days of the workshop.
ADDRESSES: The workshop will be at the NIH Natcher Conference Center,
45 Center Drive, Bethesda, Maryland 20892.
FOR FURTHER INFORMATION CONTACT: Registration and workshop information
is available at the NIH Office of Disease Prevention Web site: https://prevention.nih.gov/programs-events/pathways-to-prevention/upcoming-workshops/opioids-chronic-pain; or by sending email to
prevention@mail.nih.gov.
SUPPLEMENTARY INFORMATION: Chronic pain is a major public health
problem that is estimated to affect more than 100 million people in the
United States and about 20 to 30 percent of the population worldwide.
The prevalence of persistent pain is expected to rise in the near
future as the incidence of associated diseases (including diabetes,
obesity, cardiovascular disorders, arthritis, and cancer) increases in
the aging U.S. population.
Opioids are powerful analgesics that are commonly used and found to
be effective for many types of pain. However, opioids can produce
significant side effects, including constipation, nausea, mental
clouding, and respiratory depression, which can sometimes lead to
death.
In addition, long-term opioid use can also result in physical
dependence, making it difficult to discontinue use even when the
original cause of pain is no longer present. Furthermore, there is
mounting evidence that long-term opioid use for pain can actually
produce a chronic pain state, whereby patients find themselves in a
vicious cycle in which opioids are used to treat pain caused by
previous opioid use.
Data from the Centers for Disease Control and Prevention indicate
that the prescribing of opioids by clinicians has increased threefold
in the last 20 years, contributing to the problem of prescription
opioid abuse. Today, the number of people who die from prescription
opioids exceeds the number of those who die from heroin and cocaine,
combined.
Health care providers are in a difficult position when treating
moderate to severe chronic pain; opioid treatments may lessen the pain,
but may also cause harm to patients. Additionally, there has not been
adequate testing of opioids in terms of what types of pain they best
treat, in what populations of people, and in what manner of
administration. With insufficient data, and often inadequate training,
many clinicians prescribe too much opioid treatment when lesser amounts
of opioids or non-opioids would be effective. Alternatively, some
health care providers avoid prescribing opioids altogether for fear of
side effects and potential addiction, causing some patients to suffer
needlessly.
The 2014 ``NIH Pathways to Prevention Workshop: The Role of Opioids
in the Treatment of Chronic Pain'' will seek to clarify:
Long-term effectiveness of opioids for treating chronic
pain;
Potential risks of opioid treatment in various patient
populations;
Effects of different opioid management strategies on
outcomes related to addiction, abuse, misuse, pain, and quality of
life;
Effectiveness of risk mitigation strategies for opioid
treatment; and
Future research needs and priorities to improve the
treatment of pain with opioids.
The workshop is sponsored by the NIH Office of Disease Prevention
and the NIH Pain Consortium.
Initial planning for each Pathways to Prevention workshop is
coordinated by a Working Group that nominates panelists and speakers
and develops and finalizes questions that frame the workshop. After
finalizing the
[[Page 49333]]
questions, an evidence report is prepared by an Evidence-based Practice
Center through a contract with the Agency for Healthcare Research and
Quality (AHRQ). During the one-and-one-half-day workshop, invited
experts discuss the body of evidence, and attendees have opportunities
to provide comments during open discussion periods. After weighing
evidence from the evidence report, expert presentations, and public
comments, an unbiased, independent panel will prepare a draft report
that identifies research gaps and future research priorities. The draft
report is posted on the ODP Web site, and public comments are accepted
for two weeks. The final report is then released approximately two
weeks later.
Please Note: As part of the measures to ensure the safety of
NIH employees, patients, visitors, and property, all visitors to the
NIH Bethesda campus must be prepared to show a photo ID upon
request. Visitors may be required to pass through a metal detector
and have bags, backpacks, or purses inspected or x-rayed as they
enter the campus. For more information about the security measures
at the NIH, please visit the Web site at https://www.nih.gov/about/visitorsecurity.htm.
Dated: August 14, 2014.
Lawrence A. Tabak,
Principal Deputy Director, National Institutes of Health.
[FR Doc. 2014-19804 Filed 8-19-14; 8:45 am]
BILLING CODE 4140-01-P