Kidney Health Initiative (R18), 33201-33203 [2014-13443]
Download as PDF
Federal Register / Vol. 79, No. 111 / Tuesday, June 10, 2014 / Notices
Division of Drug Information, Center for
Drug Evaluation and Research, Food
and Drug Administration, 10903 New
Hampshire Ave., Bldg. 51, Rm. 2201,
Silver Spring, MD 20993–0002, or to the
Office of Communication, Outreach and
Development, Center for Biologics
Evaluation and Research (CBER), Food
and Drug Administration, 10903 New
Hampshire Ave., Bldg. 71, Rm. 3128,
Silver Spring, MD 20993. The draft
guidance may also be obtained by mail
by calling CBER at 1–800–835–4709 or
240–402–7800. Send one self-addressed
adhesive label to assist that office in
processing your requests. See the
SUPPLEMENTARY INFORMATION section for
electronic access to the draft guidance
document.
Submit electronic comments on the
draft guidance to https://
www.regulations.gov. Submit written
comments to the Division of Dockets
Management (HFA–305), Food and Drug
Administration, 5630 Fishers Lane, Rm.
1061, Rockville, MD 20852.
FOR FURTHER INFORMATION CONTACT:
For information concerning human
drug products: Jean Chung, Center for
Drug Evaluation and Research, Food
and Drug Administration, 10903 New
Hampshire Ave., Bldg. 22, Rm. 4466,
Silver Spring, MD, 20993–0002, 301–
796–1874.
For information concerning human
biological products: Stephen Ripley,
Center for Biologics Evaluation and
Research (HFM–17), Food and Drug
Administration, 10903 New Hampshire
Ave., Bldg. 71, Rm. 7268, Silver Spring,
MD, 20993–0002, 240–402–7911.
SUPPLEMENTARY INFORMATION:
emcdonald on DSK67QTVN1PROD with NOTICES
I. Background
FDA is announcing the availability of
a draft guidance for industry entitled
‘‘Providing Submissions in Electronic
Format—Postmarketing Safety Reports.’’
This draft guidance provides general
information pertaining to electronic
submission of postmarketing safety
reports (ICSRs, ICSR attachments, and
other postmarketing safety reports) for
the following products:
• Drug products marketed for human
use with approved new drug
applications (NDAs) and abbreviated
new drug applications (ANDAs);
• Prescription drug products
marketed for human use without an
approved NDA or ANDA;
• Biological products, other than
vaccines, marketed for human use with
approved biologic license applications
(or BLAs);
• Nonprescription (over-the-counter
or OTC) human drug products marketed
without an approved application.
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16:55 Jun 09, 2014
Jkt 232001
This draft guidance does not apply to
vaccines, human cells, tissues, and
cellular and tissue-based products
regulated under section 361 of the
Public Health Service Act, whole blood,
components of whole blood, or lot
distribution reports.
This draft guidance revises and
replaces the draft guidance for industry
entitled ‘‘Providing Regulatory
Submissions in Electronic Format—
Postmarketing Individual Case Safety
Reports,’’ issued on June 12, 2008 (73
FR 33436). Elsewhere in this issue of the
Federal Register, we are publishing a
final rule to require that mandatory
postmarketing safety reports for human
drug and biological products be
submitted to FDA in an electronic
format that the Agency can process,
review, and archive. The revised draft
guidance is intended to help persons
subject to mandatory postmarketing
safety reporting requirements comply
with the final rule. Along with other
information, the revised draft guidance
provides updated information about the
following: (1) Options for submitting
postmarketing safety reports to FDA in
electronic format, (2) the notification
that submitters will receive when FDA
has received the electronic
postmarketing safety report, and (3)
procedures for requesting temporary
waivers from the electronic submission
requirement.
The draft guidance is being issued
consistent with FDA’s good guidance
practices regulation (21 CFR 10.115).
The draft guidance, when finalized, will
represent the Agency’s current thinking
on submission of postmarketing safety
reports in electronic format. It does not
create or confer any rights for or on any
person and does not operate to bind
FDA or the public. An alternative
approach may be used if such approach
satisfies the requirements of the
applicable statutes and regulations.
II. Comments
Interested persons may submit to the
Division of Dockets Management (see
ADDRESSES) either electronic or written
comments regarding this document. It is
only necessary to send one set of
comments. Identify comments with the
docket number found in brackets in the
heading of this document. Received
comments may be seen in the Division
of Dockets Management between 9 a.m.
and 4 p.m., Monday through Friday.
III. Paperwork Reduction Act of 1995
The information collection resulting
from this draft guidance is covered by
the information collection provisions of
the final rule entitled ‘‘Postmarketing
Safety Reports for Human Drug and
PO 00000
Frm 00031
Fmt 4703
Sfmt 4703
33201
Biological Products; Electronic
Submission Requirements,’’ which is
published elsewhere in this issue of the
Federal Register. The information
collection provisions of the final rule
have been submitted to the Office of
Management and Budget (OMB) for
review, as required under section
3507(d) of the Paperwork Reduction
Act. Prior to the effective date of the
final rule, FDA will publish a notice in
the Federal Register announcing OMB’s
decision to approve, modify, or
disapprove the information collection
provisions in the final rule. An Agency
may not conduct or sponsor, and a
person is not required to respond to, a
collection of information unless it
displays a currently valid OMB control
number.
IV. Electronic Access
Persons with access to the Internet
may obtain the document at https://www.
fda.gov/Drugs/GuidanceCompliance
RegulatoryInformation/Guidances/
default.htm, https://www.fda.gov/
BiologicsBloodVaccines/Guidance
ComplianceRegulatoryInformation/
default.htm, or https://www.
regulations.gov.
Dated: June 4, 2014.
Leslie Kux,
Assistant Commissioner for Policy.
[FR Doc. 2014–13479 Filed 6–9–14; 8:45 am]
BILLING CODE 4164–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA–2014–N–0012]
Kidney Health Initiative (R18)
AGENCY:
Food and Drug Administration,
HHS.
ACTION:
Notice.
The Food and Drug
Administration (FDA) is announcing the
availability of grant funds for the
support of the Center for Drug
Evaluation and Research/Office of
Medical Policy’s Kidney Health
Initiative Program. FDA, Center for Drug
Evaluation and Research (CDER), Office
of Medical Policy (OMP) is announcing
its intent to accept and consider a single
source application for the award of a
grant to the American Society of
Nephrology (ASN) to support the
Kidney Health Initiative (KHI).
DATES: The application due date is June
30, 2014, by 11:59 p.m., EST.
ADDRESSES: Submit electronic
applications to: https://www.grants.gov.
SUMMARY:
E:\FR\FM\10JNN1.SGM
10JNN1
33202
Federal Register / Vol. 79, No. 111 / Tuesday, June 10, 2014 / Notices
For more information, see section III of
the SUPPLEMENTARY INFORMATION section
of this notice.
FOR FURTHER INFORMATION CONTACT:
Mark Lauda, Office of Medical Policy,
Center for Drug Evaluation and
Research, Food and Drug
Administration, White Oak, Bldg. 51,
Rm. 2212, Silver Spring, MD 20993,
301–796–0381, email: Mark.Lauda@
fda.hhs.gov; or Lisa Ko, Office of
Acquisition & Grants Services, Food and
Drug Administration, 5630 Fishers
Lane, Rockville, MD, 240–402–7592,
email: Lisa.Ko@fda.hhs.gov.
For more information on this funding
opportunity announcement (FOA) and
to obtain detailed requirements, please
refer to the full FOA located at https://
www.grants.gov. Search by Funding
Opportunity Number: RFA–FD–14–018.
SUPPLEMENTARY INFORMATION:
I. Funding Opportunity Description
and during stakeholder meetings.
Candidate projects that are successfully
developed and receive the endorsement
of the KHI Board of Directors are
conducted on a volunteer basis by work
groups largely (but not exclusively)
staffed by individuals from KHI member
organizations.
The opportunity for meaningful
interaction with a broad set of
stakeholders committed to improving
the evaluation of products that impact
kidney health offers significant value to
FDA and the public. Since its inception,
KHI has undertaken several projects that
have advanced the FDA mission,
including (but not limited to) projects
elucidating endpoints for lupus
nephritis trials and also providing
guidance for generating
pharmacokinetic data for critical drugs
often used in the setting of continuous
renal replacement therapies.
emcdonald on DSK67QTVN1PROD with NOTICES
RFA–FD–14–018
93.103
B. Research Objectives
A. Background
A memorandum of understanding
(MOU) between FDA and ASN signed in
September 2012 served as the basis for
the establishment of KHI. This award
will be made to ASN to enable FDA’s
support of KHI by defraying some of the
direct and indirect costs associated with
KHI and KHI projects. The ASN is a
501(c)(3) non-profit organization whose
mission is to fight against kidney
disease by educating health
professionals, sharing new knowledge,
advancing research, and advocating the
highest quality care for patients.
KHI is a public-private partnership
whose mission is to advance scientific
understanding of the kidney health and
patient safety implications of new and
existing medical products and to foster
development of therapies for disease
that affect the kidney by creating a
collaborative environment in which
FDA and the greater nephrology
community can interact to optimize
evaluation of drugs, devices, biologics,
and food products. KHI membership is
broad and includes stakeholders from
government, patient advocacy groups
and foundations, pharmaceutical and
device companies, professional
societies, dialysis providers, and
research institutions. KHI helps to effect
change through the conduct of projects
that address barriers to innovation,
facilitate critical evidence generation,
and/or elucidate safety concerns. KHI
projects may be submitted for
consideration by any of its member
organizations (including FDA).
Candidate projects are developed and
refined through Web-based interactions
The goals of this program are to
develop and maintain an administrative
and scientific infrastructure to support
the creation and execution of a series of
projects under the auspices of KHI, to
complement the goals of FDA.
The following KHI activities are
supported by this grant:
• Maintaining an adequate
administrative and scientific
infrastructure to implement all related
projects under this collaborative effort.
• Identifying and/or hiring a
sufficient number of qualified personnel
to conduct the necessary research and
project-management of all related
activities, including review of project
milestones for degree of completion,
preparation/reporting of project
findings, periodic and final reports, and
subsequent distribution in the public
domain.
• Developing plans for the conduct of
identified research plans.
• Identifying, securing, and/or
building, and effectively leveraging
other resources for the conduct of
identified projects.
• Upon completion of a given project,
generating project results and
recommendations and proposing related
studies/projects, if needed, to build on
the findings of the project and
continuing to leverage established
resources and personnel.
VerDate Mar<15>2010
16:55 Jun 09, 2014
Jkt 232001
C. Eligibility Information
The following organization is eligible
to apply: American Society of
Nephrology (ASN).
PO 00000
Frm 00032
Fmt 4703
Sfmt 4703
II. Award Information/Funds Available
A. Award Amount
This is a multi-year grant. FDA/CDER
intends to fund up to $500,000 in total
costs (direct and indirect) in fiscal year
(FY) 2014. Awards are contingent upon
the availability of funds.
Subject to the availability of Federal
funds and successful performance of the
FOA’s stated goals and objectives, 4
additional years of support may be
available. Funding beyond the first year
will be noncompetitive and will depend
on: (1) Satisfactory performance during
the preceding year and (2) the
availability of Federal FY funds.
Application budgets need to reflect
the actual needs of the proposed project
and should not exceed the following in
total costs (direct and indirect):
Year 1: $500,000
Year 2: $500,000
Year 3: $500,000
Year 4: $500,000
Year 5: $500,000
B. Length of Support
The scope of the proposed project
should determine the project period.
The maximum project period is 5 years.
III. Electronic Application,
Registration, and Submission
Only electronic applications will be
accepted. To submit an electronic
application in response to this FOA,
applicants should first review the full
announcement located at https://
www.grants.gov. Search by Funding
Opportunity Number: RFA–FD–14–018.
(FDA has verified the Web site
addresses throughout this document,
but FDA is not responsible for any
subsequent changes to the Web sites
after this document publishes in the
Federal Register.) For all electronically
submitted applications, the following
steps are required.
• Step 1: Obtain a Dun and Bradstreet
(DUNS) Number
• Step 2: Register With System for
Award Management (SAM)
• Step 3: Obtain Username & Password
• Step 4: Authorized Organization
Representative (AOR) Authorization
• Step 5: Track AOR Status
• Step 6: Register With Electronic
Research Administration (eRA)
Commons
Steps 1 through 5, in detail, can be
found at https://www07.grants.gov/
applicants/organization_
registration.jsp. Step 6, in detail, can be
found at https://commons.era.nih.gov/
commons/registration/
registrationInstructions.jsp. After you
have followed these steps, submit
E:\FR\FM\10JNN1.SGM
10JNN1
Federal Register / Vol. 79, No. 111 / Tuesday, June 10, 2014 / Notices
electronic applications to: https://
www.grants.gov.
Dated: June 4, 2014.
Leslie Kux,
Assistant Commissioner for Policy.
[FR Doc. 2014–13443 Filed 6–9–14; 8:45 am]
BILLING CODE 4160–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA–2012–P–1107]
OXIPLEX/SP Gel; FzioMed,
Incorporated’s Petition for Review of
the Food and Drug Administration’s
Denial of Premarket Approval; Notice
of Meeting Cancellation
AGENCY:
Food and Drug Administration,
HHS.
ACTION:
Notice.
The meeting of the Medical
Devices Dispute Resolution Panel
scheduled for June 10, 2014, is
cancelled. This meeting was announced
in the Federal Register of May 14, 2014.
FOR FURTHER INFORMATION CONTACT:
Pamela D. Scott, Center for Devices and
Radiological Health, 10903 New
Hampshire Ave., Bldg. 66, Rm. 3611,
Silver Spring, MD 20993–0002, 301–
796–5433, FAX: 301–847–8510, email:
pamelad.scott@fda.hhs.gov.
SUPPLEMENTARY INFORMATION: The
meeting of the Medical Devices Dispute
Resolution Panel (the panel) of the
Medical Devices Advisory Committee
scheduled for June 10, 2014, is
cancelled. On June 10, 2014, the panel
was slated to discuss the Center for
Device and Radiological Health’s
(CDRH’s) denial of a premarket approval
application (PMA) for OXIPLEX
submitted by FzioMed, the sponsor for
OXIPLEX.
On August 21, 2007, FzioMed
submitted a PMA (PMA P070023) for
OXIPLEX. OXIPLEX is an absorbable,
clear, viscoelastic gel designed to be
applied in the lower back during lumbar
spine surgery. The device’s proposed
indication is for use as a surgical
adjuvant in adult patients with primary
leg pain and severe baseline back pain
undergoing first surgical intervention
(i.e., open or endoscopic posterior
lumbar laminectomy, laminotomy, or
discectomy) for diagnosed unilateral
herniation of lumbar intervertebral disc
material associated with radiculopathy.
The proposed intended use is for onetime use, up to 3 milliliters, after
hemostasis during wound closure, as an
adjunct to primary surgical intervention
emcdonald on DSK67QTVN1PROD with NOTICES
SUMMARY:
VerDate Mar<15>2010
16:55 Jun 09, 2014
Jkt 232001
to improve patient outcomes by
reducing leg pain, back pain, and
neurologic symptoms.
On October 9, 2012, CDRH issued a
decision upholding a not approvable
letter in response to the PMA P070023
for OXIPLEX. CDRH determined that
PMA P070023 is not approvable based
on its conclusion that the data and
information offered in support of the
PMA do not provide a reasonable
assurance that the device is safe and
effective under the conditions of use
prescribed, recommended, or suggested
in the proposed labeling, as required by
section 515(d)(2) of the Federal Food,
Drug, and Cosmetic Act (the FD&C Act)
(21 U.S.C. 360e(d)(2)).
On November 5, 2012, FzioMed
requested administrative review of
CDRH’s decision to uphold its not
approvable letter. Submitted in the form
of a petition for reconsideration under
21 CFR 10.33 (see § 814.44(f)(2) (21 CFR
814.44(f)(2)), FzioMed’s petition for
review (petition) stated that, in
accordance with § 814.44(f), FzioMed
considered the decision to uphold the
not approvable letter to be a denial of
approval of PMA P070023 under
§ 814.45). Under section 515(d)(4) of the
FD&C Act, FzioMed requested review of
this denial under section 515(g)(2) of the
FD&C Act.
Accordingly, as required by
§ 814.45(e)(3), CDRH issued an order
denying approval of the PMA for
OXIPLEX on October 21, 2013. Under
section 515(g)(2) of the FD&C Act, on
October 25, 2013, FDA granted
FzioMed’s petition for review of the
order denying PMA P070023. In the
Federal Register of May 14, 2014 (79 FR
27623), the Office of the Commissioner
referred PMA P070023 and the basis for
the order denying its approval to the
Medical Devices Dispute Resolution
Panel, and announced that the panel
was scheduled to meet to discuss the
clinical and scientific issues raised by
CDRH’s Denial Order on June 10, 2014.
Since the panel meeting
announcement on May 14, 2014, the
parties have agreed that the panel
meeting should not go forward on June
10, 2014. The Agency is thereby
cancelling the June 10, 2014, meeting.
Dated: June 5, 2014.
Leslie Kux,
Assistant Commissioner for Policy.
[FR Doc. 2014–13565 Filed 6–6–14; 11:15 am]
BILLING CODE 4164–01–P
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Fmt 4703
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33203
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
Draft Report on Carcinogens
Monograph on Trichloroethylene;
Availability of Documents; Request for
Comments; Notice of Meeting
The notice announces a
meeting to peer review the Draft Report
on Carcinogens (RoC) Monograph on
Trichloroethylene (TCE). This document
was prepared by the Office of the Report
on Carcinogens (ORoC), Division of the
National Toxicology Program (DNTP),
National Institute of Environmental
Health Sciences (NIEHS). The peerreview meeting is open to the public.
Registration is requested for both public
attendance and oral comment and
required to access the webcast.
Information about the meeting and
registration are available at https://
ntp.niehs.nih.gov/go/38853.
DATES:
Meeting: August 12, 2014, 8:30 a.m.
Eastern Daylight Time (EDT) to
adjournment. Document Availability:
Draft monograph will be available by
June 30, 2014, at https://
ntp.niehs.nih.gov/go/38853.
Written Public Comments
Submissions: Deadline is July 30, 2014.
Registration for Meeting, Oral
Comments, and/or to View Webcast:
Deadline is August 5, 2014. Registration
to view the meeting via the webcast is
required.
ADDRESSES:
Meeting Location: Rodbell
Auditorium, Rall Building, NIEHS, 111
T.W. Alexander Drive, Research
Triangle Park, NC 27709.
Agency Meeting Web page: The draft
monographs, draft agenda, registration,
and other meeting materials will be
posted at https://ntp.niehs.nih.gov/go/
38853.
Webcast: The URL for viewing the
webcast will be provided to those who
register.
FOR FURTHER INFORMATION CONTACT: Dr.
Lori White, NTP Designated Federal
Official, Office of Liaison, Policy and
Review, DNTP, NIEHS, P.O. Box 12233,
MD K2–03, Research Triangle Park, NC
27709. Phone: (919) 541–9834, Fax:
(301) 480–3272, Email: whiteld@
niehs.nih.gov. Hand Delivery/Courier:
530 Davis Drive, Room 2136,
Morrisville, NC 27560.
SUPPLEMENTARY INFORMATION:
SUMMARY:
Background
The RoC is a congressionally
mandated, science-based, public health
report that identifies agents, substances,
E:\FR\FM\10JNN1.SGM
10JNN1
Agencies
[Federal Register Volume 79, Number 111 (Tuesday, June 10, 2014)]
[Notices]
[Pages 33201-33203]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2014-13443]
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA-2014-N-0012]
Kidney Health Initiative (R18)
AGENCY: Food and Drug Administration, HHS.
ACTION: Notice.
-----------------------------------------------------------------------
SUMMARY: The Food and Drug Administration (FDA) is announcing the
availability of grant funds for the support of the Center for Drug
Evaluation and Research/Office of Medical Policy's Kidney Health
Initiative Program. FDA, Center for Drug Evaluation and Research
(CDER), Office of Medical Policy (OMP) is announcing its intent to
accept and consider a single source application for the award of a
grant to the American Society of Nephrology (ASN) to support the Kidney
Health Initiative (KHI).
DATES: The application due date is June 30, 2014, by 11:59 p.m., EST.
ADDRESSES: Submit electronic applications to: https://www.grants.gov.
[[Page 33202]]
For more information, see section III of the SUPPLEMENTARY INFORMATION
section of this notice.
FOR FURTHER INFORMATION CONTACT: Mark Lauda, Office of Medical Policy,
Center for Drug Evaluation and Research, Food and Drug Administration,
White Oak, Bldg. 51, Rm. 2212, Silver Spring, MD 20993, 301-796-0381,
email: Mark.Lauda@fda.hhs.gov; or Lisa Ko, Office of Acquisition &
Grants Services, Food and Drug Administration, 5630 Fishers Lane,
Rockville, MD, 240-402-7592, email: Lisa.Ko@fda.hhs.gov.
For more information on this funding opportunity announcement (FOA)
and to obtain detailed requirements, please refer to the full FOA
located at https://www.grants.gov. Search by Funding Opportunity Number:
RFA-FD-14-018.
SUPPLEMENTARY INFORMATION:
I. Funding Opportunity Description
RFA-FD-14-018
93.103
A. Background
A memorandum of understanding (MOU) between FDA and ASN signed in
September 2012 served as the basis for the establishment of KHI. This
award will be made to ASN to enable FDA's support of KHI by defraying
some of the direct and indirect costs associated with KHI and KHI
projects. The ASN is a 501(c)(3) non-profit organization whose mission
is to fight against kidney disease by educating health professionals,
sharing new knowledge, advancing research, and advocating the highest
quality care for patients.
KHI is a public-private partnership whose mission is to advance
scientific understanding of the kidney health and patient safety
implications of new and existing medical products and to foster
development of therapies for disease that affect the kidney by creating
a collaborative environment in which FDA and the greater nephrology
community can interact to optimize evaluation of drugs, devices,
biologics, and food products. KHI membership is broad and includes
stakeholders from government, patient advocacy groups and foundations,
pharmaceutical and device companies, professional societies, dialysis
providers, and research institutions. KHI helps to effect change
through the conduct of projects that address barriers to innovation,
facilitate critical evidence generation, and/or elucidate safety
concerns. KHI projects may be submitted for consideration by any of its
member organizations (including FDA). Candidate projects are developed
and refined through Web-based interactions and during stakeholder
meetings. Candidate projects that are successfully developed and
receive the endorsement of the KHI Board of Directors are conducted on
a volunteer basis by work groups largely (but not exclusively) staffed
by individuals from KHI member organizations.
The opportunity for meaningful interaction with a broad set of
stakeholders committed to improving the evaluation of products that
impact kidney health offers significant value to FDA and the public.
Since its inception, KHI has undertaken several projects that have
advanced the FDA mission, including (but not limited to) projects
elucidating endpoints for lupus nephritis trials and also providing
guidance for generating pharmacokinetic data for critical drugs often
used in the setting of continuous renal replacement therapies.
B. Research Objectives
The goals of this program are to develop and maintain an
administrative and scientific infrastructure to support the creation
and execution of a series of projects under the auspices of KHI, to
complement the goals of FDA.
The following KHI activities are supported by this grant:
Maintaining an adequate administrative and scientific
infrastructure to implement all related projects under this
collaborative effort.
Identifying and/or hiring a sufficient number of qualified
personnel to conduct the necessary research and project-management of
all related activities, including review of project milestones for
degree of completion, preparation/reporting of project findings,
periodic and final reports, and subsequent distribution in the public
domain.
Developing plans for the conduct of identified research
plans.
Identifying, securing, and/or building, and effectively
leveraging other resources for the conduct of identified projects.
Upon completion of a given project, generating project
results and recommendations and proposing related studies/projects, if
needed, to build on the findings of the project and continuing to
leverage established resources and personnel.
C. Eligibility Information
The following organization is eligible to apply: American Society
of Nephrology (ASN).
II. Award Information/Funds Available
A. Award Amount
This is a multi-year grant. FDA/CDER intends to fund up to $500,000
in total costs (direct and indirect) in fiscal year (FY) 2014. Awards
are contingent upon the availability of funds.
Subject to the availability of Federal funds and successful
performance of the FOA's stated goals and objectives, 4 additional
years of support may be available. Funding beyond the first year will
be noncompetitive and will depend on: (1) Satisfactory performance
during the preceding year and (2) the availability of Federal FY funds.
Application budgets need to reflect the actual needs of the
proposed project and should not exceed the following in total costs
(direct and indirect):
Year 1: $500,000
Year 2: $500,000
Year 3: $500,000
Year 4: $500,000
Year 5: $500,000
B. Length of Support
The scope of the proposed project should determine the project
period. The maximum project period is 5 years.
III. Electronic Application, Registration, and Submission
Only electronic applications will be accepted. To submit an
electronic application in response to this FOA, applicants should first
review the full announcement located at https://www.grants.gov. Search
by Funding Opportunity Number: RFA-FD-14-018. (FDA has verified the Web
site addresses throughout this document, but FDA is not responsible for
any subsequent changes to the Web sites after this document publishes
in the Federal Register.) For all electronically submitted
applications, the following steps are required.
Step 1: Obtain a Dun and Bradstreet (DUNS) Number
Step 2: Register With System for Award Management (SAM)
Step 3: Obtain Username & Password
Step 4: Authorized Organization Representative (AOR)
Authorization
Step 5: Track AOR Status
Step 6: Register With Electronic Research Administration (eRA)
Commons
Steps 1 through 5, in detail, can be found at https://www07.grants.gov/applicants/organization_registration.jsp. Step 6, in
detail, can be found at https://commons.era.nih.gov/commons/registration/registrationInstructions.jsp. After you have followed
these steps, submit
[[Page 33203]]
electronic applications to: https://www.grants.gov.
Dated: June 4, 2014.
Leslie Kux,
Assistant Commissioner for Policy.
[FR Doc. 2014-13443 Filed 6-9-14; 8:45 am]
BILLING CODE 4160-01-P