Submission for OMB Review; 30-Day Comment Request; Cardiovascular Health and Needs Assessment in Washington, DC-Development of a Community-Based Behavioral Weight Loss Intervention, 14518-14519 [2014-05698]
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Federal Register / Vol. 79, No. 50 / Friday, March 14, 2014 / Notices
not operate to bind FDA or the public.
An alternative approach may be used if
such approach satisfies the
requirements of the applicable statutes
and regulations.
II. Paperwork Reduction Act of 1995
This draft guidance contains
information collection provisions that
are subject to review by the Office of
Management and Budget (OMB) under
the Paperwork Reduction Act of 1995
(the PRA) (44 U.S.C. 3501–3520). The
collection of information requested in
the draft guidance is covered under FDA
regulations at 21 CFR parts 312 and 314
and is approved under OMB Control
Numbers 0910–0014 and 0910–0001. In
accordance with the PRA, prior to
publication of any final guidance
document, FDA intends to solicit public
comment and obtain OMB approval for
any information collections
recommended in this guidance that are
new or that would represent material
modifications to those previously
approved collections of information
found in FDA regulations or guidances.
III. Comments
Interested persons may submit either
electronic comments regarding this
document to https://www.regulations.gov
or written comments to the Division of
Dockets Management (see ADDRESSES). It
is only necessary to send one set of
comments. Identify comments with the
docket number found in brackets in the
heading of this document. Received
comments may be seen in the Division
of Dockets Management between 9 a.m.
and 4 p.m., Monday through Friday, and
will be posted to the docket at https://
www.regulations.gov.
IV. Electronic Access
Persons with access to the Internet
may obtain the document at https://
www.fda.gov/Drugs/Guidance
ComplianceRegulatoryInformation/
Guidances/default.htm, https://
www.fda.gov/BiologicsBloodVaccines/
GuidanceComplianceRegulatory
Information/default.htm, or https://
www.regulations.gov.
Dated: March 11, 2014.
Peter Lurie,
Acting Associate Commissioner for Policy and
Planning.
[FR Doc. 2014–05700 Filed 3–13–14; 8:45 am]
sroberts on DSK5SPTVN1PROD with NOTICES
BILLING CODE 4160–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
Submission for OMB Review; 30-Day
Comment Request; Cardiovascular
Health and Needs Assessment in
Washington, DC—Development of a
Community-Based Behavioral Weight
Loss Intervention
Under the provisions of
Section 3507(a)(1)(D) of the Paperwork
Reduction Act of 1995, the National
Institutes of Health (NIH) has submitted
to the Office of Management and Budget
(OMB) a request for review and
approval of the information collection
listed below. This proposed information
collection was previously published in
the Federal Register on January 2, 2014,
Volume 79, Issue Number 1, pages 41–
42 and allowed 60-days for public
comment. Public comments were
received during the 60-day period. The
purpose of this notice is to allow an
additional 30 days for public comment.
The National Heart, Lung and Blood
Institute (NHLBI), National Institutes of
Health, may not conduct or sponsor,
and the respondent is not required to
respond to, an information collection
that has been extended, revised, or
implemented on or after October 1,
1995, unless it displays a currently valid
OMB control number.
Direct Comments to OMB: Written
comments and/or suggestions regarding
the item(s) contained in this notice,
especially regarding the estimated
public burden and associated response
time, should be directed to the: Office
of Management and Budget, Office of
Regulatory Affairs,
OIRA_submission@omb.eop.gov or by
fax to 202–395–6974, Attention: NIH
Desk Officer.
Comment Due Date: Comments
regarding this information collection are
best assured of having their full effect if
received within 30-days of the date of
this publication.
FOR FURTHER INFORMATION CONTACT: To
obtain a copy of the data collection
plans and instruments or request more
information on the proposed project
contact either: Eric Shropshire,
Outreach & Research Coordinator, or Dr.
Tiffany Powell-Wiley, Assistant Clinical
Investigator, CPB, DIR, NHLBI, NIH, 10
SUMMARY:
Center Drive, Building 10–CRC, 5–3340,
Bethesda, MD 20892, or call non-tollfree number Eric Shropshire, (301) 827–
4981 or Dr. Powell-Wiley, (301) 594–
3735, or Email your request, including
your address to either
Eric.Shropshire@nih.gov or
Tiffany.Powell-Wiley@nih.gov. Formal
requests for additional plans and
instruments must be requested in
writing.
Proposed Collection: Cardiovascular
Health and Needs Assessment in
Washington, DC—Development of a
Community-Based Behavioral Weight
Loss Intervention, New, National Heart,
Lung and Blood Institute (NHLBI),
National Institutes of Health (NIH).
Need and Use of Information
Collection: The purpose and use of the
information collection for this project is
to determine the prevalence of ideal,
intermediate, and poor cardiovascular
health factors based on American Heart
Association (AHA)-defined goals within
a church-based population in wards 5,
7, and 8 in Washington, DC. The
information collected will also evaluate
data from handheld devices, such as
wearable physical activity monitors or
digital cameras, to objectively measure
physical activity and dietary intake from
selected community members. This
protocol will then identify technology
that may be incorporated into future
interventions. In addition, the collected
information used will be examined for
methods of referral for treatment for
unrecognized hypertension, diabetes,
and hypercholesterolemia in the
community-based population. Social
determinants of obesity, particularly
environmental, cultural, and
psychosocial factors that might help or
hinder weight loss, will be evaluated in
the population. This information from
the screening and needs assessment will
establish a community-based
participatory research (CBPR)
partnership for the future design and
implementation of a church-based,
behavioral weight loss intervention.
OMB approval is requested for 2
years. There are no costs to respondents
other than their time. The total
estimated annualized burden hours are
2,380.
Estimated Annualized Burden Hours
A.12–1—ESTIMATES OF HOUR BURDEN
Type of
respondents
Number of
respondents
Consent Process .............................................................................................
VerDate Mar<15>2010
19:18 Mar 13, 2014
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Frequency of
response
100
E:\FR\FM\14MRN1.SGM
1
14MRN1
Average
time per
response
15/60
Annual hour
burden
25
14519
Federal Register / Vol. 79, No. 50 / Friday, March 14, 2014 / Notices
A.12–1—ESTIMATES OF HOUR BURDEN—Continued
Type of
respondents
Number of
respondents
Clinical Evaluation ...........................................................................................
Survey Instrument ............................................................................................
Device Training ................................................................................................
Health Data Monitoring ....................................................................................
Device Return ..................................................................................................
Dated: March 3, 2014.
Robert S. Balaban,
Scientific Director, Dir, NHLBI, NIH.
Dated: March 3, 2014.
Lynn Susulske,
NHLBI Project Clearance Liaison, National
Institutes of Health.
[FR Doc. 2014–05698 Filed 3–13–14; 8:45 am]
BILLING CODE 4140–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
National Institutes of Health
Prospective Grant of an Exclusive
Evaluation License Agreement: PreClinical Evaluation and Commercial
Development of Anti-Tyrosine KinaseLike Orphan Receptor 1 Antibody-Drug
Conjugates for the Treatment of
Human Cancers
AGENCY:
National Institutes of Health,
HHS.
ACTION:
Notice.
This is notice, in accordance
with 35 U.S.C. 209 and 37 CFR part 404,
that the National Institutes of Health,
Department of Health and Human
Services, is contemplating the grant of
an exclusive license to practice the
inventions embodied in U.S. Patent
Application 61/172,099 entitled ‘‘Antihuman ROR1 Antibodies’’ [HHS Ref.
E–097–2009/0–US–01], PCT
Application No. PCT/US2010/032208
entitled ‘‘Anti-human ROR1
Antibodies’’ [HHS Ref. E–097–2009/0–
PCT–02], U.S. Patent Application 61/
418,550 entitled, ‘‘Chimeric Rabbit/
Human ROR1 Antibodies’’ [HHS Ref.
No. E–039–2011/0–US–01], and PCT
Application No. PCT/US2011/062670
entitled, ‘‘Chimeric Rabbit/Human
ROR1 Antibodies’’, and all related
continuing and foreign patents/patent
applications for the technology family,
to Ardeagen Corporation. The patent
rights in these inventions have been
assigned to the Government of the
United States of America.
The prospective start-up exclusive
evaluation option license territory may
be worldwide and the field of use may
sroberts on DSK5SPTVN1PROD with NOTICES
SUMMARY:
VerDate Mar<15>2010
19:18 Mar 13, 2014
Jkt 232001
100
100
100
100
15
be limited to pre-clinical evaluation and
commercial development of an
antibody-drug conjugate comprising an
anti-tyrosine protein kinase
transmembrane receptor (ROR1)
antibody for the treatment of human
ROR1 expressing cancers, wherein the
antibody moiety comprises the antiROR1 antibodies designated as 2A2,
2D11, R11, R12, or R31. For avoidance
of doubt, this Agreement explicitly
excludes the development of an
immunotoxin comprising 2A2 and
Pseudomonas exotoxin A targeted
immunotoxins for the treatment of
human ROR1 expressing cancers. Upon
expiration or termination of the start-up
exclusive evaluation option license,
Ardeagen Corporation will have the
right to execute a start-up exclusive
patent commercialization license which
will supersede and replace the start-up
exclusive evaluation option license with
no broader territory than granted in the
start-up exclusive evaluation option
license and the field of use will be
commensurate with the commercial
development plan at the time of
conversion.
Only written comments and/or
applications for a license which are
received by the NIH Office of
Technology Transfer on or before March
31, 2014 will be considered.
ADDRESSES: Requests for copies of the
patent applications, inquiries,
comments, and other materials relating
to the contemplated exclusive
evaluation option license should be
directed to: Jennifer Wong, M.S., Senior
Licensing and Patenting Manager, Office
of Technology Transfer, National
Institutes of Health, 6011 Executive
Boulevard, Suite 325, Rockville, MD
20852–3804; Telephone: (301) 435–
4633; Facsimile: (301) 402–0220; Email:
wongje@od.nih.gov.
SUPPLEMENTARY INFORMATION: Tyrosine
kinase-like orphan receptor 1 (ROR1) is
a signature cell surface antigen for B-cell
malignancies, most notably, B-cell
chronic lymphocytic leukemia (B–CLL)
and mantle cell lymphoma (MCL) cells,
two incurable diseases. The
investigators have developed a portfolio
DATES:
PO 00000
Frm 00049
Fmt 4703
Sfmt 9990
Frequency of
response
Average
time per
response
1
1
2
2
1
Annual hour
burden
30/60
1
1
10
18/60
50
100
200
2,000
5
of chimeric anti-ROR1 monoclonal
antibodies that selectively target ROR1
malignant B-cells but not normal Bcells. These antibodies may be linked to
chemical drugs or biological toxins thus
providing targeted cytotoxic delivery to
malignant B-cells while sparing normal
cells. Moreover, as these antibodies
selectively target ROR1, they can also be
used to diagnose B-cell malignancies.
The prospective start-up exclusive
evaluation option license is being
considered under the small business
initiative launched on October 1, 2011
and will comply with the terms and
conditions of 35 U.S.C. 209 and 37 CFR
part 404. The prospective start-up
exclusive evaluation option license, and
a subsequent start-up exclusive patent
commercialization license, may be
granted unless within fifteen (15) days
from the date of this published notice,
the NIH receives written evidence and
argument that establishes that the grant
of the license would not be consistent
with the requirements of 35 U.S.C. 209
and 37 CFR part 404.
Any additional, properly filed, and
complete applications for a license in
the field of use filed in response to this
notice will be treated as objections to
the grant of the contemplated exclusive
evaluation option license. Comments
and objections submitted to this notice
will not be made available for public
inspection and, to the extent permitted
by law, will not be released under the
Freedom of Information Act, 5 U.S.C.
552.
Dated: March 12, 2014.
Richard U. Rodriguez,
Director, Division of Technology Development
& Transfer, Office of Technology Transfer,
National Institutes of Health.
[FR Doc. 2014–05678 Filed 3–13–14; 8:45 am]
BILLING CODE 4140–01–P
E:\FR\FM\14MRN1.SGM
14MRN1
Agencies
[Federal Register Volume 79, Number 50 (Friday, March 14, 2014)]
[Notices]
[Pages 14518-14519]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2014-05698]
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health
Submission for OMB Review; 30-Day Comment Request; Cardiovascular
Health and Needs Assessment in Washington, DC--Development of a
Community-Based Behavioral Weight Loss Intervention
SUMMARY: Under the provisions of Section 3507(a)(1)(D) of the Paperwork
Reduction Act of 1995, the National Institutes of Health (NIH) has
submitted to the Office of Management and Budget (OMB) a request for
review and approval of the information collection listed below. This
proposed information collection was previously published in the Federal
Register on January 2, 2014, Volume 79, Issue Number 1, pages 41-42 and
allowed 60-days for public comment. Public comments were received
during the 60-day period. The purpose of this notice is to allow an
additional 30 days for public comment. The National Heart, Lung and
Blood Institute (NHLBI), National Institutes of Health, may not conduct
or sponsor, and the respondent is not required to respond to, an
information collection that has been extended, revised, or implemented
on or after October 1, 1995, unless it displays a currently valid OMB
control number.
Direct Comments to OMB: Written comments and/or suggestions
regarding the item(s) contained in this notice, especially regarding
the estimated public burden and associated response time, should be
directed to the: Office of Management and Budget, Office of Regulatory
Affairs, OIRA_submission@omb.eop.gov or by fax to 202-395-6974,
Attention: NIH Desk Officer.
Comment Due Date: Comments regarding this information collection
are best assured of having their full effect if received within 30-days
of the date of this publication.
FOR FURTHER INFORMATION CONTACT: To obtain a copy of the data
collection plans and instruments or request more information on the
proposed project contact either: Eric Shropshire, Outreach & Research
Coordinator, or Dr. Tiffany Powell-Wiley, Assistant Clinical
Investigator, CPB, DIR, NHLBI, NIH, 10 Center Drive, Building 10-CRC,
5-3340, Bethesda, MD 20892, or call non-toll-free number Eric
Shropshire, (301) 827-4981 or Dr. Powell-Wiley, (301) 594-3735, or
Email your request, including your address to either
Eric.Shropshire@nih.gov or Tiffany.Powell-Wiley@nih.gov. Formal
requests for additional plans and instruments must be requested in
writing.
Proposed Collection: Cardiovascular Health and Needs Assessment in
Washington, DC--Development of a Community-Based Behavioral Weight Loss
Intervention, New, National Heart, Lung and Blood Institute (NHLBI),
National Institutes of Health (NIH).
Need and Use of Information Collection: The purpose and use of the
information collection for this project is to determine the prevalence
of ideal, intermediate, and poor cardiovascular health factors based on
American Heart Association (AHA)-defined goals within a church-based
population in wards 5, 7, and 8 in Washington, DC. The information
collected will also evaluate data from handheld devices, such as
wearable physical activity monitors or digital cameras, to objectively
measure physical activity and dietary intake from selected community
members. This protocol will then identify technology that may be
incorporated into future interventions. In addition, the collected
information used will be examined for methods of referral for treatment
for unrecognized hypertension, diabetes, and hypercholesterolemia in
the community-based population. Social determinants of obesity,
particularly environmental, cultural, and psychosocial factors that
might help or hinder weight loss, will be evaluated in the population.
This information from the screening and needs assessment will establish
a community-based participatory research (CBPR) partnership for the
future design and implementation of a church-based, behavioral weight
loss intervention.
OMB approval is requested for 2 years. There are no costs to
respondents other than their time. The total estimated annualized
burden hours are 2,380.
Estimated Annualized Burden Hours
A.12-1--Estimates of Hour Burden
----------------------------------------------------------------------------------------------------------------
Number of Frequency of Average time Annual hour
Type of respondents respondents response per response burden
----------------------------------------------------------------------------------------------------------------
Consent Process................................. 100 1 15/60 25
[[Page 14519]]
Clinical Evaluation............................. 100 1 30/60 50
Survey Instrument............................... 100 1 1 100
Device Training................................. 100 2 1 200
Health Data Monitoring.......................... 100 2 10 2,000
Device Return................................... 15 1 18/60 5
----------------------------------------------------------------------------------------------------------------
Dated: March 3, 2014.
Robert S. Balaban,
Scientific Director, Dir, NHLBI, NIH.
Dated: March 3, 2014.
Lynn Susulske,
NHLBI Project Clearance Liaison, National Institutes of Health.
[FR Doc. 2014-05698 Filed 3-13-14; 8:45 am]
BILLING CODE 4140-01-P