2014 Medical Countermeasures Initiative Regulatory Science Symposium, 9230 [2014-03358]
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9230
Federal Register / Vol. 79, No. 32 / Tuesday, February 18, 2014 / Notices
a first-come, first-served basis. Early
registration is recommended because
seating is limited. If you need special
accommodations due to a disability,
please enter pertinent information in the
‘‘Notes’’ section of the electronic
registration form when you register.
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA–2014–N–0001]
2014 Medical Countermeasures
Initiative Regulatory Science
Symposium
AGENCY:
Food and Drug Administration,
HHS.
ACTION:
Dated: February 11, 2014.
Peter Lurie,
Acting Associate Commissioner for Policy and
Planning.
[FR Doc. 2014–03358 Filed 2–14–14; 8:45 am]
Notice of meeting.
tkelley on DSK3SPTVN1PROD with NOTICES
BILLING CODE 4160–01–P
The Food and Drug Administration
(FDA) is announcing the following
meeting: 2014 Medical Countermeasures
initiative (MCMi) Regulatory Science
Symposium. The symposium is
intended to provide a forum for the
exchange of scientific ideas for medical
countermeasure development and
evaluation, communicate progress on
regulatory science efforts related to the
development and advancement of
medical countermeasures, facilitate
innovative directions, and inform
stakeholders on medical
countermeasure-related scientific
progress and accomplishments.
Date and Time: This symposium will
be held on June 2 and 3, 2014, from 8
a.m. to 5 p.m. Persons interested in
attending the symposium in person or
viewing via Web cast must register by
May 23, 2014, at 5 p.m. EST.
Location: The symposium will be
held at the FDA White Oak Campus,
10903 New Hampshire Ave., Building
31 Conference Center, the Great Room
(Rm. 1503), Silver Spring, MD 20993–
0002. Entrance for the public meeting
participants (non-FDA employees) is
through Building 1 where routine
security check procedures will be
performed. For parking and security
information, please refer to https://
www.fda.gov/AboutFDA/
WorkingatFDA/BuildingsandFacilities/
WhiteOakCampusInformation/
ucm241740.htm.
Contact: Rakesh Raghuwanshi, Office
of Counterterrorism and Emerging
Threats, Food and Drug Administration,
10903 New Hampshire Ave., Bldg. 32,
Rm. 4283, 301–796–4769, FAX: 301–
847–8615, email: AskMCMi@
fda.hhs.gov.
Registration: If you wish to attend the
symposium or view via Web cast, you
must register at https://www.fda.gov/
medicalcountermeasures by May 23,
2014, at 5 p.m. EST. When registering,
you must provide the following
information: (1) Your name, (2) title, (3)
company or organization (if applicable),
and (4) email address.
There is no fee to register for the
symposium and registration will be on
VerDate Mar<15>2010
20:58 Feb 14, 2014
Jkt 232001
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA–2014–N–0006]
Report on the Performance of Drug
and Biologics Firms in Conducting
Postmarketing Requirements and
Commitments; Availability
AGENCY:
Food and Drug Administration,
HHS.
ACTION:
Notice of availability.
Under the Food and Drug
Administration Modernization Act of
1997 (FDAMA), the Food and Drug
Administration (FDA) is required to
report annually in the Federal Register
on the status of postmarketing
requirements and commitments
required of, or agreed upon by, holders
of approved drug and biological
products. This notice is the Agency’s
report on the status of the studies and
clinical trials that applicants have
agreed to, or are required to, conduct.
FOR FURTHER INFORMATION CONTACT:
Cathryn C. Lee, Center for Drug
Evaluation and Research, Food and
Drug Administration, 10903 New
Hampshire Ave., Bldg. 22, Rm. 6484,
Silver Spring, MD 20993–0002, 301–
796–0700; or Stephen Ripley, Center for
Biologics Evaluation and Research
(HFM–17), Food and Drug
Administration, 1401 Rockville Pike,
Suite 200N, Rockville, MD 20852, 301–
827–6210.
SUPPLEMENTARY INFORMATION:
SUMMARY:
I. Background
A. The Food and Drug Administration
Modernization Act
Section 130(a) of FDAMA (Pub. L.
105–115) amended the Federal Food,
Drug, and Cosmetic Act (the FD&C Act)
by adding a new provision requiring
reports of certain postmarketing studies,
including clinical trials, for human drug
and biological products (section 506B of
the FD&C Act (21 U.S.C. 356b)). Section
PO 00000
Frm 00074
Fmt 4703
Sfmt 4703
506B of the FD&C Act provides FDA
with additional authority to monitor the
progress of a postmarketing study or
clinical trial that an applicant has been
required to, or has agreed to, conduct by
requiring the applicant to submit a
report annually providing information
on the status of the postmarketing
study/clinical trial. This report must
also include reasons, if any, for failure
to complete the study/clinical trial.
These studies and clinical trials are
intended to further define the safety,
efficacy, or optimal use of a product,
and therefore play a vital role in fully
characterizing the product.
Under FDAMA, commitments to
conduct postmarketing studies or
clinical trials included both studies/
clinical trials that applicants agreed to
conduct, as well as studies/clinical
trials that applicants were required to
conduct under FDA regulations.1
B. The Food and Drug Administration
Amendments Act of 2007
On September 27, 2007, the President
signed Public Law 110–85, the Food and
Drug Administration Amendments Act
of 2007 (FDAAA). Section 901, in Title
IX of FDAAA, created a new section
505(o) of the FD&C Act authorizing FDA
to require certain studies and clinical
trials for human drug and biological
products approved under section 505 of
the FD&C Act or section 351 of the
Public Health Service Act (42 U.S.C.
262). Under FDAAA, FDA has been
given additional authority to require
applicants to conduct and report on
postmarketing studies and clinical trials
to assess a known serious risk, assess
signals of serious risk, or identify an
unexpected serious risk related to the
use of a product. This new authority
became effective on March 25, 2008.
FDA may now take enforcement action
against applicants who fail to conduct
studies and clinical trials required
under FDAAA, as well as studies and
clinical trials required under FDA
regulations (see sections 505(o)(1),
502(z), and 303(f)(4) of the FD&C Act
(21 U.S.C. 355(o)(1), 352(z), and
333(f)(4))).
Although regulations implementing
FDAMA postmarketing authorities use
1 Before passage of FDAAA, FDA could require
postmarketing studies and clinical trials under the
following circumstances: To verify and describe
clinical benefit for a human drug approved in
accordance with the accelerated approval
provisions in section 506(b)(2)(A) of the FD&C Act
(21 CFR 314.510 and 601.41); for a drug approved
on the basis of animal efficacy data because human
efficacy trials are not ethical or feasible (21 CFR
314.610(b)(1) and 601.91(b)(1)); and for marketed
drugs that are not adequately labeled for children
under section 505B of the FD&C Act (Pediatric
Research Equity Act; Pub. L. 108–155).
E:\FR\FM\18FEN1.SGM
18FEN1
Agencies
[Federal Register Volume 79, Number 32 (Tuesday, February 18, 2014)]
[Notices]
[Page 9230]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2014-03358]
[[Page 9230]]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA-2014-N-0001]
2014 Medical Countermeasures Initiative Regulatory Science
Symposium
AGENCY: Food and Drug Administration, HHS.
ACTION: Notice of meeting.
-----------------------------------------------------------------------
The Food and Drug Administration (FDA) is announcing the following
meeting: 2014 Medical Countermeasures initiative (MCMi) Regulatory
Science Symposium. The symposium is intended to provide a forum for the
exchange of scientific ideas for medical countermeasure development and
evaluation, communicate progress on regulatory science efforts related
to the development and advancement of medical countermeasures,
facilitate innovative directions, and inform stakeholders on medical
countermeasure-related scientific progress and accomplishments.
Date and Time: This symposium will be held on June 2 and 3, 2014,
from 8 a.m. to 5 p.m. Persons interested in attending the symposium in
person or viewing via Web cast must register by May 23, 2014, at 5 p.m.
EST.
Location: The symposium will be held at the FDA White Oak Campus,
10903 New Hampshire Ave., Building 31 Conference Center, the Great Room
(Rm. 1503), Silver Spring, MD 20993-0002. Entrance for the public
meeting participants (non-FDA employees) is through Building 1 where
routine security check procedures will be performed. For parking and
security information, please refer to https://www.fda.gov/AboutFDA/WorkingatFDA/BuildingsandFacilities/WhiteOakCampusInformation/ucm241740.htm.
Contact: Rakesh Raghuwanshi, Office of Counterterrorism and
Emerging Threats, Food and Drug Administration, 10903 New Hampshire
Ave., Bldg. 32, Rm. 4283, 301-796-4769, FAX: 301-847-8615, email:
AskMCMi@fda.hhs.gov.
Registration: If you wish to attend the symposium or view via Web
cast, you must register at https://www.fda.gov/medicalcountermeasures by
May 23, 2014, at 5 p.m. EST. When registering, you must provide the
following information: (1) Your name, (2) title, (3) company or
organization (if applicable), and (4) email address.
There is no fee to register for the symposium and registration will
be on a first-come, first-served basis. Early registration is
recommended because seating is limited. If you need special
accommodations due to a disability, please enter pertinent information
in the ``Notes'' section of the electronic registration form when you
register.
Dated: February 11, 2014.
Peter Lurie,
Acting Associate Commissioner for Policy and Planning.
[FR Doc. 2014-03358 Filed 2-14-14; 8:45 am]
BILLING CODE 4160-01-P