Regulatory Requirements for Hearing Aid Devices and Personal Sound Amplification Products; Draft Guidance for Industry and Food and Drug Administration Staff; Availability, 66940-66941 [2013-26691]
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66940
Federal Register / Vol. 78, No. 216 / Thursday, November 7, 2013 / Notices
information are sponsors that develop
drugs and biological products.
Burden Estimate: This guidance
outlines FDA’s policies and procedures
related to the following expedited
programs for serious conditions: (1) Fast
track designation including rolling
review, (2) breakthrough therapy
designation, (3) accelerated approval,
and (4) priority review designation. In
addition, this guidance describes
threshold criteria generally applicable to
these expedited programs.
This guidance refers to previously
approved collections of information
found in FDA regulations. The
collections of information in 21 CFR
parts 202.1, 314, and 601, and sections
505(a), 506(a)(1), 735, and 736 of the
Federal Food, Drug, and Cosmetic Act
(FD&C Act) (21 U.S.C. 355(a), 356(a)(1),
379(g), and 379(h)) have been approved
under OMB control numbers 0910–
0686, 0910–0001, 0910–0338, 0910–
0014, and 0910–0297.
This guidance proposes the following
new collections of information:
Priority Review Designation Request.
The guidance describes that a sponsor
may expressly request priority review of
an application. Based on information
from FDA’s databases and information
available to FDA, we estimate that
approximately 47 sponsors will prepare
and submit approximately 1 priority
to FDA during the preapproval period.
The regulations further provide that
after 120 days following marketing
approval, unless otherwise informed by
the Agency, the applicant must submit
promotional materials at least 30 days
prior to the intended time of initial
dissemination of the labeling or initial
publication of the advertisement.
Currently, FDA has OMB approval for
the submission of copies of all
promotional materials under part 601
(OMB control number 0910–0338) but
does not have approval for the
submission of copies of all promotional
materials under part 314.
Based on information from FDA’s
databases and information available to
FDA, we estimate that approximately 20
sponsors will submit promotional
materials for accelerated approval 7
times annually in accordance with
§ 314.550 and that the burden for each
submission will be approximately 120
hours (a total of 16,800 hours).
In the Federal Register of June 26,
2013 (78 FR 38349), FDA published a
60-day notice requesting public
comment on the proposed collection of
information. FDA received 26
comments. However, these comments
did not address the information
collection.
FDA estimates the burden of this
collection of information as follows:
review designation submission in
accordance with the guidance and that
the added burden for each submission
will be approximately 30 hours to
develop and submit to FDA as part of
the application (totaling 1,410 hours).
Breakthrough Therapy Designation
Request. The guidance describes the
process for sponsors to request
breakthrough therapy designation in an
application. Based on information
available to FDA, we estimate that
approximately 24 sponsors will prepare
approximately 1 breakthrough therapy
designation submission in accordance
with the guidance and that the added
burden for each submission will be
approximately 70 hours to prepare and
submit (totaling 1,680 hours).
Promotional Materials for Accelerated
Approval Under Part 314. The guidance
describes section 506(b)(2)(B) of the
FD&C Act and FDA’s accelerated
approval regulations (§§ 314.550 and
601.45). These provisions authorize
FDA to require sponsors to submit
copies of all promotional materials to
the Agency for consideration prior to
their dissemination. The regulations
provide that copies of all promotional
materials including promotional
labeling as well as advertisements
intended for dissemination or
publication within 120 days following
marketing approval must be submitted
TABLE 1—ESTIMATED ANNUAL REPORTING BURDEN 1
Number of
respondents
Guidance on expedited programs
Number of
responses per
respondent
Average
burden per
response
Total annual
responses
Total hours
Priority Review Designation Request ..................................
Breakthrough Therapy Designation Request ......................
Promotional Materials for Accelerated Approval Under
§ 314.550 ..........................................................................
47
24
1
1
47
24
30
70
1,410
1,680
20
7
140
120
16,800
Total hours ....................................................................
........................
........................
........................
........................
19,890
1 There
are no capital costs or operating and maintenance costs associated with this collection of information.
Dated: November 1, 2013.
Leslie Kux,
Assistant Commissioner for Policy.
[FR Doc. 2013–26695 Filed 11–6–13; 8:45 am]
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA–2013–D–1295]
BILLING CODE 4160–01–P
tkelley on DSK3SPTVN1PROD with NOTICES
Regulatory Requirements for Hearing
Aid Devices and Personal Sound
Amplification Products; Draft
Guidance for Industry and Food and
Drug Administration Staff; Availability
AGENCY:
Food and Drug Administration,
HHS.
ACTION:
Notice.
The Food and Drug
Administration (FDA) is announcing the
availability of the draft guidance
SUMMARY:
VerDate Mar<15>2010
16:24 Nov 06, 2013
Jkt 232001
PO 00000
Frm 00051
Fmt 4703
Sfmt 4703
entitled ‘‘Regulatory Requirements for
Hearing Aid Devices and Personal
Sound Amplification Products.’’ This
draft guidance clarifies the distinction
between hearing aids and personal
sound amplification products (PSAPs),
as well as the regulatory controls that
apply to each. This draft guidance is not
final nor is it in effect at this time.
Although you can comment on
any guidance at any time (see 21 CFR
10.115(g)(5)), to ensure that the Agency
considers your comment on this draft
guidance before it begins work on the
final version of the guidance, submit
either electronic or written comments
on the draft guidance by February 5,
2014.
DATES:
E:\FR\FM\07NON1.SGM
07NON1
Federal Register / Vol. 78, No. 216 / Thursday, November 7, 2013 / Notices
Submit written requests for
single copies of the draft guidance
document entitled ‘‘Regulatory
Requirements for Hearing Aid Devices
and Personal Sound Amplification
Products’’ to the Division of Small
Manufacturers, International, and
Consumer Assistance, Center for
Devices and Radiological Health, Food
and Drug Administration, 10903 New
Hampshire Ave., Bldg. 66, Rm. 4613,
Silver Spring, MD 20993–0002. Send
one self-addressed adhesive label to
assist that office in processing your
request, or fax your request to 301–847–
8149. See the SUPPLEMENTARY
INFORMATION section for information on
electronic access to the guidance.
Submit electronic comments on the
draft guidance to https://
www.regulations.gov. Submit written
comments to the Division of Dockets
Management (HFA–305), Food and Drug
Administration, 5630 Fishers Lane, Rm.
1061, Rockville, MD 20852. Identify
comments with the docket number
found in brackets in the heading of this
document.
ADDRESSES:
Eric
A. Mann, Center for Devices and
Radiological Health, Food and Drug
Administration, 10903 New Hampshire
Ave., Bldg. 66, Rm. 2438, Silver Spring,
MD 20993–0002, 301–796–5620.
FOR FURTHER INFORMATION CONTACT:
SUPPLEMENTARY INFORMATION:
II. Significance of Guidance
This draft guidance is being issued
consistent with FDA’s good guidance
practices regulation (21 CFR 10.115).
The draft guidance, when finalized, will
represent the Agency’s current thinking
on the definitions and regulatory
requirements for hearing aids and
PSAPs. It does not create or confer any
rights for or on any person and does not
operate to bind FDA or the public. An
alternative approach may be used if
such approach satisfies the
requirements of the applicable statute
and regulations.
III. Electronic Access
Persons interested in obtaining a copy
of the draft guidance may do so by using
the Internet. A search capability for all
CDRH guidance documents is available
at https://www.fda.gov/MedicalDevices/
DeviceRegulationandGuidance/
GuidanceDocuments/default.htm.
Guidance documents are also available
at https://www.regulations.gov. To
receive ‘‘Regulatory Requirements for
Hearing Aid Devices and Personal
Sound Amplification Products’’ you
may either send an email request to
dsmica@fda.hhs.gov to receive an
electronic copy of the document or send
a fax request to 301–847–8149 to receive
a hard copy. Please use the document
number 1832 to identify the guidance
you are requesting.
tkelley on DSK3SPTVN1PROD with NOTICES
I. Background
IV. Paperwork Reduction Act of 1995
Since issuance of the February 25,
2009 guidance entitled, ‘‘Regulatory
Requirements for Hearing Aid Devices
and Personal Sound Amplification
Products’’ FDA has become aware of a
lack of clarity regarding how the Agency
defines a hearing aid versus a personal
sound amplification product (PSAP),
which has also led, in some cases, to
inappropriate application of regulatory
requirements for such products. These
inconsistent interpretations of the
definitions may inadvertently result in
hearing-impaired consumers bypassing
safeguards that were implemented to
promote the prompt diagnosis of
treatable medical conditions causing
hearing loss. To ensure consistent
interpretation, consistent application of
relevant regulatory requirements, and
adequate protection of the public health,
FDA seeks to further clarify the
definitions of hearing aids and PSAPs.
This draft guidance, when finalized,
will supersede the guidance entitled
‘‘Guidance for Industry and FDA Staff:
Regulatory Requirements for Hearing
Aid Devices and Personal Sound
Amplification Products,’’ dated
February 25, 2009.
This draft guidance refers to
previously approved collections of
information found in FDA regulations.
These collections of information are
subject to review by the Office of
Management and Budget (OMB) under
the Paperwork Reduction Act of 1995
(44 U.S.C. 3501–3520). The collections
of information in 21 CFR part 801 have
been approved under OMB control
number 0910–0485; and the collections
of information in 21 CFR part 807
subpart E have been approved under
OMB control number 0910–0120.
VerDate Mar<15>2010
16:24 Nov 06, 2013
Jkt 232001
V. Comments
Interested persons may submit either
electronic comments regarding this
document to https://www.regulations.gov
or written comments to the Division of
Dockets Management (see ADDRESSES). It
is only necessary to send one set of
comments. Identify comments with the
docket number found in brackets in the
heading of this document. Received
comments may be seen in the Division
of Dockets Management between 9 a.m.
and 4 p.m., Monday through Friday, and
will be posted to the docket at https://
www.regulations.gov.
PO 00000
Frm 00052
Fmt 4703
Sfmt 4703
66941
Dated: November 1, 2013.
Leslie Kux,
Assistant Commissioner for Policy.
[FR Doc. 2013–26691 Filed 11–6–13; 8:45 am]
BILLING CODE 4160–01–P
DEPARTMENT OF HEALTH AND
HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA–2011–D–0567]
Design Considerations for Pivotal
Clinical Investigations for Medical
Devices; Guidance for Industry,
Clinical Investigators, Institutional
Review Boards and Food and Drug
Administration Staff; Availability
AGENCY:
Food and Drug Administration,
HHS.
ACTION:
Notice.
The Food and Drug
Administration (FDA) is announcing the
availability of the guidance entitled
‘‘Design Considerations for Pivotal
Clinical Investigations for Medical
Devices.’’ This document is intended to
provide guidance to those involved in
designing clinical studies intended to
support premarket submissions for
medical devices and for FDA staff who
review those submissions. This
guidance document describes different
study design principles relevant to the
development of medical device clinical
studies that can be used to fulfill
premarket clinical data requirements.
DATES: Submit either electronic or
written comments on this guidance at
any time. General comments on agency
guidance documents are welcome at any
time.
ADDRESSES: Submit written requests for
single copies of the guidance document
entitled ‘‘Design Considerations for
Pivotal Clinical Investigations for
Medical Devices’’ to the Division of
Small Manufacturers, International, and
Consumer Assistance, Center for
Devices and Radiological Health
(CDRH), Food and Drug Administration,
10903 New Hampshire Ave., Bldg. 66,
rm. 4613, Silver Spring, MD 20993–
0002; or the Office of Communication,
Outreach and Development (HFM–40),
Center for Biologics Evaluation and
Research (CBER), Food and Drug
Administration, 1401 Rockville Pike,
suite 200N, Rockville, MD 20852–1448.
Send one self-addressed adhesive label
to assist that office in processing your
request, or fax your request to CDRH at
301–847–8149. See the SUPPLEMENTARY
INFORMATION section for information on
electronic access to the guidance.
SUMMARY:
E:\FR\FM\07NON1.SGM
07NON1
Agencies
[Federal Register Volume 78, Number 216 (Thursday, November 7, 2013)]
[Notices]
[Pages 66940-66941]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2013-26691]
-----------------------------------------------------------------------
DEPARTMENT OF HEALTH AND HUMAN SERVICES
Food and Drug Administration
[Docket No. FDA-2013-D-1295]
Regulatory Requirements for Hearing Aid Devices and Personal
Sound Amplification Products; Draft Guidance for Industry and Food and
Drug Administration Staff; Availability
AGENCY: Food and Drug Administration, HHS.
ACTION: Notice.
-----------------------------------------------------------------------
SUMMARY: The Food and Drug Administration (FDA) is announcing the
availability of the draft guidance entitled ``Regulatory Requirements
for Hearing Aid Devices and Personal Sound Amplification Products.''
This draft guidance clarifies the distinction between hearing aids and
personal sound amplification products (PSAPs), as well as the
regulatory controls that apply to each. This draft guidance is not
final nor is it in effect at this time.
DATES: Although you can comment on any guidance at any time (see 21 CFR
10.115(g)(5)), to ensure that the Agency considers your comment on this
draft guidance before it begins work on the final version of the
guidance, submit either electronic or written comments on the draft
guidance by February 5, 2014.
[[Page 66941]]
ADDRESSES: Submit written requests for single copies of the draft
guidance document entitled ``Regulatory Requirements for Hearing Aid
Devices and Personal Sound Amplification Products'' to the Division of
Small Manufacturers, International, and Consumer Assistance, Center for
Devices and Radiological Health, Food and Drug Administration, 10903
New Hampshire Ave., Bldg. 66, Rm. 4613, Silver Spring, MD 20993-0002.
Send one self-addressed adhesive label to assist that office in
processing your request, or fax your request to 301-847-8149. See the
SUPPLEMENTARY INFORMATION section for information on electronic access
to the guidance.
Submit electronic comments on the draft guidance to https://www.regulations.gov. Submit written comments to the Division of Dockets
Management (HFA-305), Food and Drug Administration, 5630 Fishers Lane,
Rm. 1061, Rockville, MD 20852. Identify comments with the docket number
found in brackets in the heading of this document.
FOR FURTHER INFORMATION CONTACT: Eric A. Mann, Center for Devices and
Radiological Health, Food and Drug Administration, 10903 New Hampshire
Ave., Bldg. 66, Rm. 2438, Silver Spring, MD 20993-0002, 301-796-5620.
SUPPLEMENTARY INFORMATION:
I. Background
Since issuance of the February 25, 2009 guidance entitled,
``Regulatory Requirements for Hearing Aid Devices and Personal Sound
Amplification Products'' FDA has become aware of a lack of clarity
regarding how the Agency defines a hearing aid versus a personal sound
amplification product (PSAP), which has also led, in some cases, to
inappropriate application of regulatory requirements for such products.
These inconsistent interpretations of the definitions may inadvertently
result in hearing-impaired consumers bypassing safeguards that were
implemented to promote the prompt diagnosis of treatable medical
conditions causing hearing loss. To ensure consistent interpretation,
consistent application of relevant regulatory requirements, and
adequate protection of the public health, FDA seeks to further clarify
the definitions of hearing aids and PSAPs.
This draft guidance, when finalized, will supersede the guidance
entitled ``Guidance for Industry and FDA Staff: Regulatory Requirements
for Hearing Aid Devices and Personal Sound Amplification Products,''
dated February 25, 2009.
II. Significance of Guidance
This draft guidance is being issued consistent with FDA's good
guidance practices regulation (21 CFR 10.115). The draft guidance, when
finalized, will represent the Agency's current thinking on the
definitions and regulatory requirements for hearing aids and PSAPs. It
does not create or confer any rights for or on any person and does not
operate to bind FDA or the public. An alternative approach may be used
if such approach satisfies the requirements of the applicable statute
and regulations.
III. Electronic Access
Persons interested in obtaining a copy of the draft guidance may do
so by using the Internet. A search capability for all CDRH guidance
documents is available at https://www.fda.gov/MedicalDevices/DeviceRegulationandGuidance/GuidanceDocuments/default.htm. Guidance
documents are also available at https://www.regulations.gov. To receive
``Regulatory Requirements for Hearing Aid Devices and Personal Sound
Amplification Products'' you may either send an email request to
dsmica@fda.hhs.gov to receive an electronic copy of the document or
send a fax request to 301-847-8149 to receive a hard copy. Please use
the document number 1832 to identify the guidance you are requesting.
IV. Paperwork Reduction Act of 1995
This draft guidance refers to previously approved collections of
information found in FDA regulations. These collections of information
are subject to review by the Office of Management and Budget (OMB)
under the Paperwork Reduction Act of 1995 (44 U.S.C. 3501-3520). The
collections of information in 21 CFR part 801 have been approved under
OMB control number 0910-0485; and the collections of information in 21
CFR part 807 subpart E have been approved under OMB control number
0910-0120.
V. Comments
Interested persons may submit either electronic comments regarding
this document to https://www.regulations.gov or written comments to the
Division of Dockets Management (see ADDRESSES). It is only necessary to
send one set of comments. Identify comments with the docket number
found in brackets in the heading of this document. Received comments
may be seen in the Division of Dockets Management between 9 a.m. and 4
p.m., Monday through Friday, and will be posted to the docket at https://www.regulations.gov.
Dated: November 1, 2013.
Leslie Kux,
Assistant Commissioner for Policy.
[FR Doc. 2013-26691 Filed 11-6-13; 8:45 am]
BILLING CODE 4160-01-P